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Search results 1 to 100 out of 180 for Ppp1r15a

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Patel V
Year: 2019
Journal: Sci Rep
Title: Inactivation of Ppp1r15a minimises weight gain and insulin resistance during caloric excess in female mice.
Volume: 9
Issue: 1
Pages: 2903
Publication
First Author: Monkley S
Year: 2021
Journal: Sci Rep
Title: Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF.
Volume: 11
Issue: 1
Pages: 21584
Publication      
First Author: Kidwell A
Year: 2022
Journal: J Am Soc Nephrol
Title: Translation Rescue by Targeting Ppp1r15a through Its Upstream Open Reading Frame in Sepsis-Induced Acute Kidney Injury in a Murine Model.
Publication
First Author: Harding HP
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development.
Volume: 106
Issue: 6
Pages: 1832-7
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lord KA
Year: 1990
Journal: Nucleic Acids Res
Title: Sequence of MyD116 cDNA: a novel myeloid differentiation primary response gene induced by IL6.
Volume: 18
Issue: 9
Pages: 2823
Publication
First Author: Novoa I
Year: 2001
Journal: J Cell Biol
Title: Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha.
Volume: 153
Issue: 5
Pages: 1011-22
Publication
First Author: Novoa I
Year: 2003
Journal: EMBO J
Title: Stress-induced gene expression requires programmed recovery from translational repression.
Volume: 22
Issue: 5
Pages: 1180-7
Publication
First Author: Kojima E
Year: 2003
Journal: FASEB J
Title: The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice.
Volume: 17
Issue: 11
Pages: 1573-5
Publication
First Author: Patterson AD
Year: 2006
Journal: Mol Cell Biol
Title: Gadd34 requirement for normal hemoglobin synthesis.
Volume: 26
Issue: 5
Pages: 1644-53
Publication    
First Author: Chen Y
Year: 2021
Journal: Elife
Title: Prolonging the integrated stress response enhances CNS remyelination in an inflammatory environment.
Volume: 10
Publication
First Author: Lin Y
Year: 2012
Journal: PLoS One
Title: Interferon-γ activates nuclear factor-κ B in oligodendrocytes through a process mediated by the unfolded protein response.
Volume: 7
Issue: 5
Pages: e36408
Publication
First Author: Krzyzosiak A
Year: 2018
Journal: Cell
Title: Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B.
Volume: 174
Issue: 5
Pages: 1216-1228.e19
Publication  
First Author: Perego J
Year: 2018
Journal: Sci Signal
Title: Guanabenz inhibits TLR9 signaling through a pathway that is independent of eIF2α dephosphorylation by the GADD34/PP1c complex.
Volume: 11
Issue: 514
Publication  
First Author: Liu L
Year: 2014
Journal: Biomed Res Int
Title: Negative regulation of GADD34 on myofibroblasts during cutaneous wound healing.
Volume: 2014
Pages: 137049
Publication
First Author: Nishio N
Year: 2014
Journal: Immunol Cell Biol
Title: Loss of GADD34 induces early age-dependent deviation to the myeloid lineage.
Volume: 92
Issue: 2
Pages: 170-80
Publication  
First Author: Nishio N
Year: 2015
Journal: Sci Rep
Title: GADD34-deficient mice develop obesity, nonalcoholic fatty liver disease, hepatic carcinoma and insulin resistance.
Volume: 5
Pages: 13519
Publication  
First Author: Ito S
Year: 2015
Journal: Sci Rep
Title: GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy.
Volume: 5
Pages: 8327
Publication  
First Author: Sun Y
Year: 2015
Journal: Oxid Med Cell Longev
Title: Enhancement of the acrolein-induced production of reactive oxygen species and lung injury by GADD34.
Volume: 2015
Pages: 170309
Publication
First Author: Tanaka Y
Year: 2015
Journal: Br J Cancer
Title: Effects of growth arrest and DNA damage-inducible protein 34 (GADD34) on inflammation-induced colon cancer in mice.
Volume: 113
Issue: 4
Pages: 669-79
Publication
First Author: Chen N
Year: 2015
Journal: Cancer Immunol Immunother
Title: Growth arrest and DNA damage-inducible protein (GADD34) enhanced liver inflammation and tumorigenesis in a diethylnitrosamine (DEN)-treated murine model.
Volume: 64
Issue: 6
Pages: 777-89
Publication  
First Author: Ohri SS
Year: 2013
Journal: Neurobiol Dis
Title: Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury.
Volume: 58
Pages: 29-37
Publication  
First Author: Ito S
Year: 2016
Journal: Cell Death Dis
Title: GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation.
Volume: 7
Pages: e2219
Publication
First Author: Ohri SS
Year: 2014
Journal: PLoS One
Title: Inhibition of GADD34, the stress-inducible regulatory subunit of the endoplasmic reticulum stress response, does not enhance functional recovery after spinal cord injury.
Volume: 9
Issue: 11
Pages: e109703
Publication
First Author: Cheng G
Year: 2001
Journal: J Virol
Title: AlaArg motif in the carboxyl terminus of the gamma(1)34.5 protein of herpes simplex virus type 1 is required for the formation of a high-molecular-weight complex that dephosphorylates eIF-2alpha.
Volume: 75
Issue: 8
Pages: 3666-74
Publication
First Author: Hollander MC
Year: 1997
Journal: J Biol Chem
Title: Mammalian GADD34, an apoptosis- and DNA damage-inducible gene.
Volume: 272
Issue: 21
Pages: 13731-7
Publication
First Author: Clavarino G
Year: 2012
Journal: PLoS Pathog
Title: Induction of GADD34 is necessary for dsRNA-dependent interferon-β production and participates in the control of Chikungunya virus infection.
Volume: 8
Issue: 5
Pages: e1002708
Publication  
First Author: Saltykova IV
Year: 2022
Journal: Int J Mol Sci
Title: GADD34 Ablation Exacerbates Retinal Degeneration in P23H RHO Mice.
Volume: 23
Issue: 22
GXD Expression      
Probe: MGI:1927778
Assay Type: Northern blot
Annotation Date: 2000-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:1927786
Age: embryonic day 8.5
Specimen Label: +/-
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1927778
Assay Type: Northern blot
Annotation Date: 2000-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:1927786
Age: embryonic day 8.5
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1927778
Assay Type: Northern blot
Annotation Date: 2000-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:1927786
Age: embryonic day 8.5
Specimen Label: +/-
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1927778
Assay Type: Northern blot
Annotation Date: 2000-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:1927786
Age: embryonic day 8.5
Specimen Label: -/-
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1927778
Assay Type: Northern blot
Annotation Date: 2000-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:1927786
Age: embryonic day 8.5
Specimen Label: +/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1927778
Assay Type: Northern blot
Annotation Date: 2000-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:1927786
Age: embryonic day 8.5
Specimen Label: -/-
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1927778
Assay Type: Northern blot
Annotation Date: 2000-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:1927786
Age: embryonic day 8.5
Specimen Label: +/+
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:1927778
Assay Type: Northern blot
Annotation Date: 2000-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:1927786
Age: embryonic day 8.5
Specimen Label: +/-
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:1927778
Assay Type: Northern blot
Annotation Date: 2000-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:1927786
Age: embryonic day 8.5
Specimen Label: +/-
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:5304183
Age: embryonic day 8.5
Specimen Label: E8.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5304183
Age: embryonic day 9.5
Specimen Label: E9.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5304183
Age: embryonic day 10.5
Specimen Label: E10.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:5304183
Age: embryonic day 11.5
Specimen Label: E11.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:5304183
Age: embryonic day 12.5
Specimen Label: E12.5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5304183
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:5304183
Age: embryonic day 14.5
Specimen Label: E14.5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:5304183
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:5304183
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5304185
Age: postnatal month 2
Specimen Label: brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5304185
Age: postnatal month 2
Specimen Label: heart
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5304185
Age: postnatal month 2
Specimen Label: lung
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5304185
Age: postnatal month 2
Specimen Label: thymus
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5304185
Age: postnatal month 2
Specimen Label: spleen
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5304185
Age: postnatal month 2
Specimen Label: liver
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:5304185
Age: postnatal month 2
Specimen Label: small intestine
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5304185
Age: postnatal month 2
Specimen Label: kidney
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:5304185
Age: postnatal month 2
Specimen Label: muscle
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5304185
Age: postnatal month 2
Specimen Label: testis
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5304185
Age: postnatal month 2
Specimen Label: ovary
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5304182
Assay Type: Northern blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:5304185
Age: embryonic day 12.5
Specimen Label: embryo 12.5 d
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5304279
Assay Type: Western blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5304280
Age: postnatal month 2
Specimen Label: UT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5304279
Assay Type: Western blot
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5304280
Age: postnatal month 2
Specimen Label: UT
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5304279
Assay Type: Western blot
Annotation Date: 2012-01-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5304280
Age: postnatal month 2
Specimen Label: UT
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:6423167
Assay Type: RT-PCR
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423453
Age: postnatal month 1
Image: S7
Specimen Label: Con
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6423167
Assay Type: RT-PCR
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423453
Age: postnatal month 1
Image: S7
Specimen Label: CKO
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7506355
Assay Type: RT-PCR
Annotation Date: 2023-07-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3263528
Stage: TS28
Assay Id: MGI:7506363
Age: postnatal month 1
Specimen Label: Control
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7506355
Assay Type: RT-PCR
Annotation Date: 2023-07-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3263528
Stage: TS28
Assay Id: MGI:7506363
Age: postnatal month 1
Specimen Label: CHOP-/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7616339
Age: embryonic day 13.5
Specimen Label: 13.5 dpc
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7616339
Age: embryonic day 13.5
Specimen Label: 13.5 dpc
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7616339
Age: embryonic day 13.5
Specimen Label: 13.5 dpc
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7616339
Age: embryonic day 16.5
Specimen Label: 16.5 dpc
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7616339
Age: embryonic day 16.5
Specimen Label: 16.5 dpc
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:7616339
Age: embryonic day 16.5
Specimen Label: 16.5 dpc
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7616339
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7616339
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7616339
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 9