|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 85 out of 85 for Prcd

0.064s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Protein Domain
Type: Family
Description: PRCD is a secreted protein and a photoreceptor outer segment (OS) disc-specific protein involved in vision [, ]. Defects in the corresponding genes causes autosomal recessive retinal degeneration [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Murphy J
Year: 2016
Journal: J Biol Chem
Title: Palmitoylation of Progressive Rod-Cone Degeneration (PRCD) Regulates Protein Stability and Localization.
Volume: 291
Issue: 44
Pages: 23036-23046
Publication
First Author: Zangerl B
Year: 2006
Journal: Genomics
Title: Identical mutation in a novel retinal gene causes progressive rod-cone degeneration in dogs and retinitis pigmentosa in humans.
Volume: 88
Issue: 5
Pages: 551-63
Protein
Organism: Mus musculus/domesticus
Length: 53  
Fragment?: false
Publication  
First Author: Remez L
Year: 2014
Journal: Exp Eye Res
Title: The progressive rod-cone degeneration (PRCD) protein is secreted through the conventional ER/Golgi-dependent pathway.
Volume: 125
Pages: 217-25
Publication
First Author: Spencer WJ
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: PRCD is essential for high-fidelity photoreceptor disc formation.
Volume: 116
Issue: 26
Pages: 13087-13096
Publication
First Author: Skiba NP
Year: 2013
Journal: J Proteome Res
Title: Proteomic identification of unique photoreceptor disc components reveals the presence of PRCD, a protein linked to retinal degeneration.
Volume: 12
Issue: 6
Pages: 3010-8
Publication
First Author: Sechrest ER
Year: 2020
Journal: Sci Rep
Title: Loss of PRCD alters number and packaging density of rhodopsin in rod photoreceptor disc membranes.
Volume: 10
Issue: 1
Pages: 17885
Publication  
First Author: Remez L
Year: 2020
Journal: Int J Mol Sci
Title: TULP1 and TUB Are Required for Specific Localization of PRCD to Photoreceptor Outer Segments.
Volume: 21
Issue: 22
Publication
First Author: Spencer WJ
Year: 2016
Journal: Biochemistry
Title: Progressive Rod-Cone Degeneration (PRCD) Protein Requires N-Terminal S-Acylation and Rhodopsin Binding for Photoreceptor Outer Segment Localization and Maintaining Intracellular Stability.
Volume: 55
Issue: 36
Pages: 5028-37
Publication
First Author: Allon G
Year: 2019
Journal: Hum Mol Genet
Title: PRCD is concentrated at the base of photoreceptor outer segments and is involved in outer segment disc formation.
Volume: 28
Issue: 24
Pages: 4078-4088
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:6469318
Assay Type: RT-PCR
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716822
Stage: TS22
Assay Id: MGI:6469332
Age: embryonic day 14.0
Specimen Label: E14
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6469318
Assay Type: RT-PCR
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:6469332
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6469318
Assay Type: RT-PCR
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6469332
Age: postnatal day 150
Specimen Label: P150
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6469318
Assay Type: RT-PCR
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6469349
Age: postnatal week 10
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6469318
Assay Type: RT-PCR
Annotation Date: 2020-10-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6469349
Age: postnatal week 10
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6469322
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6469334
Age: postnatal week 10
Specimen Label: 3E wt
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6469322
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3568828
Stage: TS28
Assay Id: MGI:6469334
Age: postnatal week 10
Specimen Label: 3E ko
Detected: false
Specimen Num: 5
GXD Expression  
Probe: MGI:6469322
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6469334
Age: postnatal adult
Note: Expression is seen exclusively in the photoreceptor outer segments; the high background of the rod labeling made it difficult to determine if this included expression in the cones.
Specimen Label: 1E
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6469322
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6469334
Age: postnatal adult
Note: Expression is seen exclusively in the photoreceptor outer segments; double labeling demonstrates this includes expression in the rods.
Specimen Label: 1B
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6469322
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6469334
Age: postnatal adult
Note: Expression is seen in the photoreceptor outer segments; since these mutants lack rods, this demonstrates there is expression in the cones.
Specimen Label: 1H
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6469322
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6469344
Age: postnatal adult
Note: Expression is concentrated in the compartment of disc neogenesis at the outer segment base; it is also seen at the rim of the outer segment in both the disc and plasma membranes. This is a rod cell.
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6469322
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6469344
Age: postnatal adult
Note: Expression is concentrated in the compartment of disc neogenesis at the outer segment base of the rod cell pictured in (A).
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6469322
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6469344
Age: postnatal adult
Note: Expression is seen on the disc rim, in disc membranes and the plasma membrane; this is a rod cell.
Specimen Label: 2C
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6469322
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6469344
Age: postnatal adult
Note: Expression is concentrated in the compartment of disc neogenesis at the outer segment base; this is a rod cell.
Specimen Label: 2D
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6469322
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6469344
Age: postnatal adult
Note: Expression is concentrated in the compartment of disc neogenesis at the outer segment base; this is a cone cell.
Specimen Label: 2E
Detected: true
Specimen Num: 5
Publication
First Author: Lin Q
Year: 2006
Journal: Nucleic Acids Res
Title: Mutagenesis of diploid mammalian genes by gene entrapment.
Volume: 34
Issue: 20
Pages: e139
Publication      
First Author: Mouse Genome Informatics and VEGA Genome Database Project
Year: 2006
Journal: Database Release
Title: Collaboration to Associate VEGA (Vertebrate Genome Annotation) Mouse Gene Models with MGI Markers
Publication  
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
UniProt Feature
Begin: 1
Description: Photoreceptor disk component PRCD
Type: chain
End: 53
Publication
First Author: Gu W
Year: 1999
Journal: Invest Ophthalmol Vis Sci
Title: Evaluation of the APOH gene as a positional candidate for prcd in dogs.
Volume: 40
Issue: 6
Pages: 1229-37
Protein
Organism: Mus musculus/domesticus
Length: 106  
Fragment?: false
Publication
First Author: Ray K
Year: 1996
Journal: Invest Ophthalmol Vis Sci
Title: Nonallelism of erd and prcd and exclusion of the canine RDS/peripherin gene as a candidate for both retinal degeneration loci.
Volume: 37
Issue: 5
Pages: 783-94
DO Term
Publication  
First Author: Cocito C
Year: 2016
Journal: Front Cell Neurosci
Title: Alterations of Cell Proliferation and Apoptosis in the Hypoplastic Reeler Cerebellum.
Volume: 10
Pages: 141
Publication
First Author: Zangerl B
Year: 2002
Journal: Gene
Title: Molecular cloning, characterization and mapping of the canine glucocorticoid receptor DNA binding factor 1 (GRLF1).
Volume: 294
Issue: 1-2
Pages: 167-76
Publication
First Author: Ray K
Year: 1997
Journal: Curr Eye Res
Title: Canine rod transducin alpha-1: cloning of the cDNA and evaluation of the gene as a candidate for progressive retinal atrophy.
Volume: 16
Issue: 1
Pages: 71-7
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112