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Search results 1 to 100 out of 121 for Prdm2

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0.046s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Domain
Type: Family
Description: PRDM2 (also known as RIZ) is a transcriptional regulator and tumour suppressor that catalyzes methylation of lysine 9 of histone H3. Its PR domain is responsible for its catalytic activity []. PRDM2 belongs to the PRDM family, whose members are characterised by the presence of an N-terminal PR (PRDI-BF1 and RIZ1 homology) domain followed by multiple zinc fingers which confer DNA binding activity. PR domains are only distantly related to the classical SET methyltransferase domains []. PRDM2 interacts with another tumour suppressor, the retinoblastoma protein (Rb). A short motif, IRCDE, in the acidic region (AR) of RIZ is important for this interaction [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 1670  
Fragment?: false
Publication
First Author: Sun Y
Year: 2015
Journal: Biochemistry
Title: Structural and functional characterization of the acidic region from the RIZ tumor suppressor.
Volume: 54
Issue: 6
Pages: 1390-400
Publication
First Author: Briknarová K
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Structural studies of the SET domain from RIZ1 tumor suppressor.
Volume: 366
Issue: 3
Pages: 807-13
Protein
Organism: Mus musculus/domesticus
Length: 1709  
Fragment?: false
Publication
First Author: Wu H
Year: 2013
Journal: Cell Rep
Title: Molecular basis for the regulation of the H3K4 methyltransferase activity of PRDM9.
Volume: 5
Issue: 1
Pages: 13-20
Publication
First Author: Wada S
Year: 2015
Journal: Histochem Cell Biol
Title: H3K9MTase G9a is essential for the differentiation and growth of tenocytes in vitro.
Volume: 144
Issue: 1
Pages: 13-20
Publication
First Author: Ideno H
Year: 2013
Journal: Gene Expr Patterns
Title: Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development.
Volume: 13
Issue: 3-4
Pages: 84-90
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Carling T
Year: 2004
Journal: Mol Cell Biol
Title: A histone methyltransferase is required for maximal response to female sex hormones.
Volume: 24
Issue: 16
Pages: 7032-42
Publication
First Author: Xie X
Year: 2016
Journal: Obesity (Silver Spring)
Title: Tumor suppressor RIZ1 in obesity and the PI3K/AKT/mTOR pathway.
Volume: 24
Issue: 2
Pages: 389-97
Publication
First Author: Noman AS
Year: 2010
Journal: Cell Immunol
Title: Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation.
Volume: 264
Issue: 2
Pages: 114-8
GXD Expression    
Probe: MGI:6194851
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194882
Age: embryonic day 16.5
Image: 4
Specimen Label: a
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6194851
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194882
Age: embryonic day 16.5
Image: 4
Specimen Label: b
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6194851
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194882
Age: embryonic day 16.5
Image: 4
Specimen Label: c
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6194851
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194882
Age: embryonic day 16.5
Image: 4
Specimen Label: d
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2854023
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1869223
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2853323
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6194780
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3262520
Stage: TS20
Assay Id: MGI:6194863
Age: embryonic day 12.5
Image: 1D
Specimen Label: 1D
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:6194780
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6194863
Age: embryonic day 14.5
Image: 2D
Note: Very weak expression was detected in proliferating chondrocytes. A significant increase in expression was observed in the prehypertrophic and hypertrophic chondrocytes.
Specimen Label: 2D
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6194780
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6194863
Age: embryonic day 16.5
Image: 3D
Note: Expression was detected in the prehypertrophic and hypertrophic chondrocytes and the trabecular bones.
Specimen Label: 3D
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6888188
Assay Type: RNA in situ
Annotation Date: 2022-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6888193
Age: embryonic day 16.5
Note: Expression in cells overlapping with or adjacent to Tnmd-positive tendon cells
Specimen Label: 2G
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6888188
Assay Type: RNA in situ
Annotation Date: 2022-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6888193
Age: embryonic day 16.5
Note: Expression in cells overlapping with or adjacent to Tnmd-positive tendon cells
Specimen Label: 2H
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6888188
Assay Type: RNA in situ
Annotation Date: 2022-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6888193
Age: embryonic day 18.5
Note: Expression in cells overlapping with or adjacent to Tnmd-positive tendon cells
Specimen Label: S3G
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6888188
Assay Type: RNA in situ
Annotation Date: 2022-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6888193
Age: embryonic day 18.5
Note: Expression in cells overlapping with or adjacent to Tnmd-positive tendon cells
Specimen Label: S3H
Detected: true
Specimen Num: 4
Publication
First Author: Zhou W
Year: 2008
Journal: PLoS One
Title: Requirement of RIZ1 for cancer prevention by methyl-balanced diet.
Volume: 3
Issue: 10
Pages: e3390
Publication
First Author: Buyse IM
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein.
Volume: 92
Issue: 10
Pages: 4467-71
Publication
First Author: Steele-Perkins G
Year: 2001
Journal: Genes Dev
Title: Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily.
Volume: 15
Issue: 17
Pages: 2250-62
Publication
First Author: Mock BA
Year: 1996
Journal: Mamm Genome
Title: Riz maps to distal chromosome 4 near genes involved in tumorigenesis and nerve degeneration.
Volume: 7
Issue: 8
Pages: 637
Publication
First Author: Allis CD
Year: 2007
Journal: Cell
Title: New nomenclature for chromatin-modifying enzymes.
Volume: 131
Issue: 4
Pages: 633-6
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer