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Search results 1 to 100 out of 651 for Prdx6

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Type Details Score
Gene
9588 | PRDX6
Type: gene
Organism: human
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Gene
469589 | PRDX6
Type: gene
Organism: chimpanzee
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Gene
429062 | PRDX6
Type: gene
Organism: chicken
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Gene
393778 | prdx6
Type: gene
Organism: zebrafish
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Gene
706486 | PRDX6
Type: gene
Organism: macaque, rhesus
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Gene
394706 | prdx6
Type: gene
Organism: frog, western clawed
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Gene
282438 | PRDX6
Type: gene
Organism: cattle
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Gene
94167 | Prdx6
Type: gene
Organism: rat
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Gene
480069 | PRDX6
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:894320 | Prdx6
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
101928673 | PRDX6-AS1
Type: gene
Organism: human
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Publication
28199527 | J:294921
First Author: Melhem H
Year: 2017
Journal: J Crohns Colitis
Title: Prdx6 Deficiency Ameliorates DSS Colitis: Relevance of Compensatory Antioxidant Mechanisms.
Volume: 11
Issue: 7
Pages: 871-884
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Publication
30097850 | J:295025
First Author: Yeo IJ
Year: 2019
Journal: Mol Neurobiol
Title: PRDX6 Inhibits Neurogenesis through Downregulation of WDFY1-Mediated TLR4 Signal.
Volume: 56
Issue: 5
Pages: 3132-3144
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Publication
26327204 | J:332071
First Author: Yun HM
Year: 2015
Journal: Oncotarget
Title: PRDX6 controls multiple sclerosis by suppressing inflammation and blood brain barrier disruption.
Volume: 6
Issue: 25
Pages: 20875-84
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Publication
25193021 | J:332073
First Author: Yun HM
Year: 2015
Journal: Mol Neurobiol
Title: PRDX6 Exacerbates Dopaminergic Neurodegeneration in a MPTP Mouse Model of Parkinson's Disease.
Volume: 52
Issue: 1
Pages: 422-31
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Publication
14572613 | J:86528
First Author: Phelan SA
Year: 2003
Journal: Free Radic Biol Med
Title: Overexpression of Prdx6 reduces H2O2 but does not prevent diet-induced atherosclerosis in the aortic root.
Volume: 35
Issue: 9
Pages: 1110-20
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Publication
25582888 | J:220347
 
First Author: Yun HM
Year: 2015
Journal: Free Radic Biol Med
Title: PRDX6 promotes tumor development via the JAK2/STAT3 pathway in a urethane-induced lung tumor model.
Volume: 80
Pages: 136-44
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Publication
21677259 | J:177622
First Author: Fatma N
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis.
Volume: 301
Issue: 4
Pages: C954-67
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Publication
24910119 | J:225859
First Author: Chhunchha B
Year: 2014
Journal: FEBS J
Title: Aberrant sumoylation signaling evoked by reactive oxygen species impairs protective function of Prdx6 by destabilization and repression of its transcription.
Volume: 281
Issue: 15
Pages: 3357-81
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Publication
23771816 | J:332072
First Author: Yun HM
Year: 2013
Journal: Mol Neurobiol
Title: Acceleration of the development of Alzheimer's disease in amyloid beta-infused peroxiredoxin 6 overexpression transgenic mice.
Volume: 48
Issue: 3
Pages: 941-51
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Publication
32171727 | J:295017
 
First Author: Lee DH
Year: 2020
Journal: Redox Biol
Title: Peroxiredoxin 6 mediates acetaminophen-induced hepatocyte death through JNK activation.
Volume: 32
Pages: 101496
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Publication
18260127 | J:294926
First Author: Wang Y
Year: 2008
Journal: J Cell Biochem
Title: Peroxiredoxin 6 as an antioxidant enzyme: protection of lung alveolar epithelial type II cells from H2O2-induced oxidative stress.
Volume: 104
Issue: 4
Pages: 1274-85
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Publication
26265052 | J:294922
 
First Author: Asuni AA
Year: 2015
Journal: Neurochem Int
Title: Antioxidant peroxiredoxin 6 protein rescues toxicity due to oxidative stress and cellular hypoxia in vitro, and attenuates prion-related pathology in vivo.
Volume: 90
Pages: 152-65
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Publication
20939758 | J:294923
First Author: Sundar IK
Year: 2010
Journal: Exp Lung Res
Title: Peroxiredoxin 6 differentially regulates acute and chronic cigarette smoke&#x2013;mediated lung inflammatory response and injury.
Volume: 36
Issue: 8
Pages: 451-62
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Publication
26921317 | J:237406
First Author: Sorokina EM
Year: 2016
Journal: J Biol Chem
Title: Mutation of Serine 32 to Threonine in Peroxiredoxin 6 Preserves Its Structure and Enzymatic Function but Abolishes Its Trafficking to Lamellar Bodies.
Volume: 291
Issue: 17
Pages: 9268-80
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Publication
32907613 | J:295013
First Author: Pankiewicz JE
Year: 2020
Journal: Mol Neurodegener
Title: Peroxiredoxin 6 mediates protective function of astrocytes in Aβ proteostasis.
Volume: 15
Issue: 1
Pages: 50
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Publication
16399955 | J:120623
First Author: Wang Y
Year: 2006
Journal: Am J Respir Cell Mol Biol
Title: Transgenic mice overexpressing peroxiredoxin 6 show increased resistance to lung injury in hyperoxia.
Volume: 34
Issue: 4
Pages: 481-6
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Publication
26211509 | J:295022
First Author: Kim DH
Year: 2015
Journal: Arthritis Rheumatol
Title: Exacerbation of collagen antibody-induced arthritis in transgenic mice overexpressing peroxiredoxin 6.
Volume: 67
Issue: 11
Pages: 3058-69
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Publication
19386791 | J:294925
First Author: Roede JR
Year: 2009
Journal: J Pharmacol Exp Ther
Title: Overexpression of peroxiredoxin 6 does not prevent ethanol-mediated oxidative stress and may play a role in hepatic lipid accumulation.
Volume: 330
Issue: 1
Pages: 79-88
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Publication
18025307 | J:135552
First Author: Kümin A
Year: 2007
Journal: J Cell Biol
Title: Peroxiredoxin 6 is required for blood vessel integrity in wounded skin.
Volume: 179
Issue: 4
Pages: 747-60
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Publication
35705035 | J:332074
First Author: Wagner MP
Year: 2022
Journal: Cell Rep
Title: Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target.
Volume: 39
Issue: 11
Pages: 110923
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Publication
26830860 | J:231458
First Author: Fisher AB
Year: 2016
Journal: J Lipid Res
Title: A novel lysophosphatidylcholine acyl transferase activity is expressed by peroxiredoxin 6.
Volume: 57
Issue: 4
Pages: 587-96
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Publication
26117327 | J:239138
 
First Author: Li H
Year: 2015
Journal: Free Radic Biol Med
Title: Critical role of peroxiredoxin 6 in the repair of peroxidized cell membranes following oxidative stress.
Volume: 87
Pages: 356-65
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Publication
36403738 | J:332076
First Author: Paluchova V
Year: 2022
Journal: Free Radic Biol Med
Title: The role of peroxiredoxin 6 in biosynthesis of FAHFAs.
Volume: 193
Issue: Pt 2
Pages: 787-794
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Publication
12732627 | J:84376
First Author: Wang X
Year: 2003
Journal: J Biol Chem
Title: Mice with targeted mutation of peroxiredoxin 6 develop normally but are susceptible to oxidative stress.
Volume: 278
Issue: 27
Pages: 25179-90
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Publication
15488866 | J:109702
First Author: Wang X
Year: 2004
Journal: Atherosclerosis
Title: Peroxiredoxin 6 deficiency and atherosclerosis susceptibility in mice: significance of genetic background for assessing atherosclerosis.
Volume: 177
Issue: 1
Pages: 61-70
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Publication
33632301 | J:303861
First Author: Phasuk S
Year: 2021
Journal: Mol Brain
Title: Enhanced contextual fear memory in peroxiredoxin 6 knockout mice is associated with hyperactivation of MAPK signaling pathway.
Volume: 14
Issue: 1
Pages: 42
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Publication
15818411 | J:111863
First Author: Fatma N
Year: 2005
Journal: Cell Death Differ
Title: Impaired homeostasis and phenotypic abnormalities in Prdx6-/-mice lens epithelial cells by reactive oxygen species: increased expression and activation of TGFbeta.
Volume: 12
Issue: 7
Pages: 734-50
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Publication
23576553 | J:198347
First Author: Rolfs F
Year: 2013
Journal: Cancer Res
Title: Dual role of the antioxidant enzyme peroxiredoxin 6 in skin carcinogenesis.
Volume: 73
Issue: 11
Pages: 3460-9
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Publication
33874992 | J:304973
First Author: Phasuk S
Year: 2021
Journal: Mol Brain
Title: Lack of the peroxiredoxin 6 gene causes impaired spatial memory and abnormal synaptic plasticity.
Volume: 14
Issue: 1
Pages: 72
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Publication
24947358 | J:230174
First Author: Pacifici F
Year: 2014
Journal: Diabetes
Title: Peroxiredoxin 6, a novel player in the pathogenesis of diabetes.
Volume: 63
Issue: 10
Pages: 3210-20
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Publication
26792942 | J:232441
First Author: Ozkosem B
Year: 2016
Journal: Biol Reprod
Title: Absence of Peroxiredoxin 6 Amplifies the Effect of Oxidant Stress on Mobility and SCSA/CMA3 Defined Chromatin Quality and Impairs Fertilizing Ability of Mouse Spermatozoa.
Volume: 94
Issue: 3
Pages: 68
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Publication
19033532 | J:146328
First Author: Eismann T
Year: 2009
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice.
Volume: 296
Issue: 2
Pages: G266-74
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Publication
16766642 | J:116312
First Author: Nagy N
Year: 2006
Journal: Am J Physiol Heart Circ Physiol
Title: Targeted disruption of peroxiredoxin 6 gene renders the heart vulnerable to ischemia-reperfusion injury.
Volume: 291
Issue: 6
Pages: H2636-40
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Publication
26398495 | J:295004
First Author: Sorrell SL
Year: 2016
Journal: Kidney Int
Title: Renal peroxiredoxin 6 interacts with anion exchanger 1 and plays a novel role in pH homeostasis.
Volume: 89
Issue: 1
Pages: 105-112
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Publication
15772425 | J:105202
First Author: Fisher AB
Year: 2005
Journal: J Lipid Res
Title: Altered lung phospholipid metabolism in mice with targeted deletion of lysosomal-type phospholipase A2.
Volume: 46
Issue: 6
Pages: 1248-56
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Publication
25796034 | J:295007
 
First Author: Ozkosem B
Year: 2015
Journal: Redox Biol
Title: Advancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice.
Volume: 5
Pages: 15-23
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Publication
29021631 | J:256370
First Author: Moawad AR
Year: 2017
Journal: Sci Rep
Title: Deficiency of peroxiredoxin 6 or inhibition of its phospholipase A2 activity impair the in vitro sperm fertilizing competence in mice.
Volume: 7
Issue: 1
Pages: 12994
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Publication
15528033 | J:94787
First Author: Wang Y
Year: 2004
Journal: Free Radic Biol Med
Title: Lung injury and mortality with hyperoxia are increased in peroxiredoxin 6 gene-targeted mice.
Volume: 37
Issue: 11
Pages: 1736-43
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Publication
27884794 | J:294927
 
First Author: Yang D
Year: 2017
Journal: Respir Physiol Neurobiol
Title: Peroxiredoxin 6 suppresses Muc5ac overproduction in LPS-induced airway inflammation through H2O2-EGFR-MAPK signaling pathway.
Volume: 236
Pages: 84-90
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Publication
16321424 | J:105825
First Author: Kubo E
Year: 2006
Journal: Mech Ageing Dev
Title: Development- and age-associated expression pattern of peroxiredoxin 6, and its regulation in murine ocular lens.
Volume: 127
Issue: 3
Pages: 249-56
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Publication
19889963 | J:157517
First Author: Kubo E
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: Protein expression profiling of lens epithelial cells from Prdx6-depleted mice and their vulnerability to UV radiation exposure.
Volume: 298
Issue: 2
Pages: C342-54
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Publication
31949886 | J:292509
 
First Author: Arriga R
Year: 2019
Journal: Oxid Med Cell Longev
Title: Peroxiredoxin 6 Is a Key Antioxidant Enzyme in Modulating the Link between Glycemic and Lipogenic Metabolism.
Volume: 2019
Pages: 9685607
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Publication
30702344 | J:273236
First Author: Vázquez-Medina JP
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Genetic inactivation of the phospholipase A2 activity of peroxiredoxin 6 in mice protects against LPS-induced acute lung injury.
Volume: 316
Issue: 4
Pages: L656-L668
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Publication
20627125 | J:164603
First Author: Liu G
Year: 2010
Journal: Free Radic Biol Med
Title: Comparison of glutathione peroxidase 1 and peroxiredoxin 6 in protection against oxidative stress in the mouse lung.
Volume: 49
Issue: 7
Pages: 1172-81
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Publication
23164639 | J:213113
First Author: Zhou S
Year: 2013
Journal: Int J Biochem Cell Biol
Title: Functional interaction of glutathione S-transferase pi and peroxiredoxin 6 in intact cells.
Volume: 45
Issue: 2
Pages: 401-7
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Publication
29549163 | J:262212
First Author: Kuda O
Year: 2018
Journal: Diabetes
Title: Nrf2-Mediated Antioxidant Defense and Peroxiredoxin 6 Are Linked to Biosynthesis of Palmitic Acid Ester of 9-Hydroxystearic Acid.
Volume: 67
Issue: 6
Pages: 1190-1199
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Publication
19562038 | J:150184
First Author: Trudel S
Year: 2009
Journal: PLoS One
Title: Peroxiredoxin 6 fails to limit phospholipid peroxidation in lung from Cftr-knockout mice subjected to oxidative challenge.
Volume: 4
Issue: 6
Pages: e6075
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Publication
21262967 | J:295024
First Author: Chatterjee S
Year: 2011
Journal: J Biol Chem
Title: Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages.
Volume: 286
Issue: 13
Pages: 11696-706
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Publication
26907692 | J:233718
First Author: Kook S
Year: 2016
Journal: J Biol Chem
Title: Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficient pearl Mice.
Volume: 291
Issue: 16
Pages: 8414-27
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Publication
20713718 | J:163744
First Author: Hirota Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Uterine FK506-binding protein 52 (FKBP52)-peroxiredoxin-6 (PRDX6) signaling protects pregnancy from overt oxidative stress.
Volume: 107
Issue: 35
Pages: 15577-82
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Publication
23401562 | J:197839
First Author: Krishnaiah SY
Year: 2013
Journal: FASEB J
Title: p67(phox) terminates the phospholipase A(2)-derived signal for activation of NADPH oxidase (NOX2).
Volume: 27
Issue: 5
Pages: 2066-73
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Publication
21857934 | J:176505
First Author: Wang JL
Year: 2011
Journal: PLoS One
Title: Calcium prevents tumorigenesis in a mouse model of colorectal cancer.
Volume: 6
Issue: 8
Pages: e22566
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Strain
MGI:6143749 | B6(129S4)-Prdx6<tm5.1Abf>/Mmnc
Attribute String: mutant strain, targeted mutation
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Protein Coding Gene
MGP_CAROLIEiJ_G0014763 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016651 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016632 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016598 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016593 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016417 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_894320 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016498 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016496 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016569 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016521 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017090 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015783 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016059 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027999 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015570 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9291135 | J:54513
 
First Author: Munz B
Year: 1997
Journal: Biochem J
Title: A novel type of glutathione peroxidase: expression and regulation during wound repair.
Volume: 326 ( Pt 2)
Pages: 579-85
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Publication
10395907 | J:56276
First Author: Lee TH
Year: 1999
Journal: Gene
Title: Characterization of the murine gene encoding 1-Cys peroxiredoxin and identification of highly homologous genes.
Volume: 234
Issue: 2
Pages: 337-44
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Publication
30683539 | J:294924
 
First Author: Wang X
Year: 2019
Journal: Int Immunopharmacol
Title: Peroxiredoxin 6 knockout aggravates cecal ligation and puncture-induced acute lung injury.
Volume: 68
Pages: 252-258
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Publication
21200322 | J:295015
First Author: Yang D
Year: 2011
Journal: Crit Care Med
Title: Deletion of peroxiredoxin 6 potentiates lipopolysaccharide-induced acute lung injury in mice.
Volume: 39
Issue: 4
Pages: 756-64
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Publication
4041781 | J:8013
First Author: Goldman D
Year: 1985
Journal: Brain Res
Title: Genetic brain polypeptide variants in inbred mice and in mouse strains with high and low sensitivity to alcohol.
Volume: 341
Issue: 1
Pages: 130-8
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Publication
9612290 | J:47772
First Author: Kim TS
Year: 1998
Journal: Am J Physiol
Title: Cloning and expression of rat lung acidic Ca(2+)-independent PLA2 and its organ distribution.
Volume: 274
Issue: 5 Pt 1
Pages: L750-61
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Publication
12547829 | J:82781
First Author: Smani T
Year: 2003
Journal: J Biol Chem
Title: Ca2+-independent phospholipase A2 is a novel determinant of store-operated Ca2+ entry.
Volume: 278
Issue: 14
Pages: 11909-15
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Publication
17003478 | J:113375
First Author: Kümin A
Year: 2006
Journal: Am J Pathol
Title: Peroxiredoxin 6 is a potent cytoprotective enzyme in the epidermis.
Volume: 169
Issue: 4
Pages: 1194-205
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GXD Expression
GXD Expression
     
Probe: MGI:1344599
Assay Type: Northern blot
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2669383
Age: postnatal adult
Specimen Label: B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1344599
Assay Type: Northern blot
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2669383
Age: postnatal adult
Specimen Label: L
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1344599
Assay Type: Northern blot
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2669383
Age: postnatal adult
Specimen Label: S
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1344599
Assay Type: Northern blot
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2669383
Age: postnatal adult
Specimen Label: K
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1344599
Assay Type: Northern blot
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2669383
Age: postnatal adult
Specimen Label: Li
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:1344599
Assay Type: Northern blot
Annotation Date: 2003-08-18
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2669383
Age: postnatal adult
Specimen Label: T
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:1344599
Assay Type: Northern blot
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:2669385
Age: embryonic day 7.5
Specimen Label: 7.5dpc F
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:1344599
Assay Type: Northern blot
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:2669385
Age: embryonic day 7.5
Specimen Label: 7.5dpc E
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:1344599
Assay Type: Northern blot
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:2669385
Age: embryonic day 8.5
Specimen Label: 8.5dpc F
Detected: true
Specimen Num: 3
•
•
•
•
•




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