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Search results 1 to 100 out of 586 for Prf1

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Hits by Strain

Hits by Category

Type Details Score
Gene
5551 | PRF1
Type: gene
Organism: human
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Gene
450512 | PRF1
Type: gene
Organism: chimpanzee
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Gene
369025 | PRF1
Type: gene
Organism: cattle
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Gene
710241 | PRF1
Type: gene
Organism: macaque, rhesus
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Gene
101750363 | PRF1
Type: gene
Organism: chicken
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Gene
100491518 | prf1
Type: gene
Organism: frog, western clawed
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Gene
50669 | Prf1
Type: gene
Organism: rat
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Gene
489030 | PRF1
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:97551 | Prf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
1505959 | J:1688
First Author: Fink TM
Year: 1992
Journal: Genomics
Title: Human perforin (PRF1) maps to 10q22, a region that is syntenic with mouse chromosome 10.
Volume: 13
Issue: 4
Pages: 1300-2
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Publication
17088087 | J:116116
First Author: van Dommelen SL
Year: 2006
Journal: Immunity
Title: Perforin and granzymes have distinct roles in defensive immunity and immunopathology.
Volume: 25
Issue: 5
Pages: 835-48
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Publication
31015190 | J:280266
First Author: Albeituni S
Year: 2019
Journal: Blood
Title: Mechanisms of action of ruxolitinib in murine models of hemophagocytic lymphohistiocytosis.
Volume: 134
Issue: 2
Pages: 147-159
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Publication
19720840 | J:153778
First Author: Lee SH
Year: 2009
Journal: J Exp Med
Title: Activating receptors promote NK cell expansion for maintenance, IL-10 production, and CD8 T cell regulation during viral infection.
Volume: 206
Issue: 10
Pages: 2235-51
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Publication
18563383 | J:138005
First Author: Pearson T
Year: 2008
Journal: Diabetologia
Title: A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function.
Volume: 51
Issue: 8
Pages: 1449-56
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Protein Coding Gene
MGP_CAROLIEiJ_G0015364 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017277 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017255 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017215 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017215 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017038 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97551 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017673 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017115 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017109 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017190 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017137 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016673 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030780 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016177 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
2783549 | J:9554
First Author: Kwon BS
Year: 1989
Journal: Biochem Biophys Res Commun
Title: The structure of the mouse lymphocyte pore-forming protein perforin.
Volume: 158
Issue: 1
Pages: 1-10
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Publication
3261391 | J:9295
First Author: Shinkai Y
Year: 1988
Journal: Nature
Title: Homology of perforin to the ninth component of complement (C9).
Volume: 334
Issue: 6182
Pages: 525-7
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Publication
2783486 | J:9549
First Author: Lowrey DM
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Cloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9.
Volume: 86
Issue: 1
Pages: 247-51
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Publication
1401900 | J:2869
First Author: Lichtenheld MG
Year: 1992
Journal: J Immunol
Title: Structure and function of the murine perforin promoter and upstream region. Reciprocal gene activation or silencing in perforin positive and negative cells.
Volume: 149
Issue: 8
Pages: 2619-26
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Publication
8164737 | J:17986
First Author: Kägi D
Year: 1994
Journal: Nature
Title: Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice.
Volume: 369
Issue: 6475
Pages: 31-7
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Publication
7526382 | J:21531
First Author: Walsh CM
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Immune function in mice lacking the perforin gene.
Volume: 91
Issue: 23
Pages: 10854-8
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Publication
21037563 | J:175325
First Author: Law RH
Year: 2010
Journal: Nature
Title: The structural basis for membrane binding and pore formation by lymphocyte perforin.
Volume: 468
Issue: 7322
Pages: 447-51
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Publication
7533086 | J:23268
First Author: Schulz M
Year: 1995
Journal: Eur J Immunol
Title: Acute rejection of vascular heart allografts by perforin-deficient mice.
Volume: 25
Issue: 2
Pages: 474-80
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Publication
15070687 | J:115473
First Author: Dyer CM
Year: 2004
Journal: Blood
Title: Unexpectedly, induction of cytotoxic T lymphocytes enhances the humoral response after DNA immunization.
Volume: 103
Issue: 8
Pages: 3073-5
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Publication
24259502 | J:207103
First Author: Johnson TS
Year: 2014
Journal: J Immunol
Title: Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis.
Volume: 192
Issue: 1
Pages: 84-91
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Publication
31509742 | J:300289
First Author: Freeman AJ
Year: 2019
Journal: Cell Rep
Title: Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion.
Volume: 28
Issue: 11
Pages: 2784-2794.e5
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Publication
23746652 | J:207586
First Author: Olson JA
Year: 2013
Journal: Immunity
Title: Effector-like CD8⁺ T cells in the memory population mediate potent protective immunity.
Volume: 38
Issue: 6
Pages: 1250-60
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Publication
22250087 | J:181169
First Author: Enomoto N
Year: 2012
Journal: J Immunol
Title: Allergen-specific CTL require perforin expression to suppress allergic airway inflammation.
Volume: 188
Issue: 4
Pages: 1734-41
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Publication
19338979 | J:148284
First Author: Brown DM
Year: 2009
Journal: Cell Immunol
Title: IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells.
Volume: 257
Issue: 1-2
Pages: 69-79
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Publication
18413767 | J:133960
First Author: Epardaud M
Year: 2008
Journal: Cancer Res
Title: Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells.
Volume: 68
Issue: 8
Pages: 2972-83
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Publication
26384546 | J:233784
First Author: Zlotnikov-Klionsky Y
Year: 2015
Journal: Immunity
Title: Perforin-Positive Dendritic Cells Exhibit an Immuno-regulatory Role in Metabolic Syndrome and Autoimmunity.
Volume: 43
Issue: 4
Pages: 776-87
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Publication
32286313 | J:287242
First Author: Garofalo S
Year: 2020
Journal: Nat Commun
Title: Natural killer cells modulate motor neuron-immune cell cross talk in models of Amyotrophic Lateral Sclerosis.
Volume: 11
Issue: 1
Pages: 1773
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Publication
17545627 | J:122174
First Author: Street SE
Year: 2007
Journal: Cancer Res
Title: Host perforin reduces tumor number but does not increase survival in oncogene-driven mammary adenocarcinoma.
Volume: 67
Issue: 11
Pages: 5454-60
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Publication
24477907 | J:209821
First Author: Bouwer AL
Year: 2014
Journal: J Immunol
Title: NK cells are required for dendritic cell-based immunotherapy at the time of tumor challenge.
Volume: 192
Issue: 5
Pages: 2514-21
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Publication
9916723 | J:83174
First Author: White DW
Year: 1999
Journal: J Immunol
Title: Perforin-deficient CD8+ T cells: in vivo priming and antigen-specific immunity against Listeria monocytogenes.
Volume: 162
Issue: 2
Pages: 980-8
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Publication
19878357 | J:154771
First Author: Silverio JC
Year: 2010
Journal: Int J Exp Pathol
Title: Perforin-expressing cytotoxic cells contribute to chronic cardiomyopathy in Trypanosoma cruzi infection.
Volume: 91
Issue: 1
Pages: 72-86
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Publication
15899830 | J:98547
First Author: Liu K
Year: 2005
Journal: Cancer Res
Title: Immune selection and emergence of aggressive tumor variants as negative consequences of Fas-mediated cytotoxicity and altered IFN-gamma-regulated gene expression.
Volume: 65
Issue: 10
Pages: 4376-88
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Publication
14530349 | J:120042
First Author: Messingham KA
Year: 2003
Journal: J Immunol
Title: Deficient anti-listerial immunity in the absence of perforin can be restored by increasing memory CD8+ T cell numbers.
Volume: 171
Issue: 8
Pages: 4254-62
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Publication
9506704 | J:114262
First Author: Felzen B
Year: 1998
Journal: Circ Res
Title: Fas (CD95/Apo-1)-mediated damage to ventricular myocytes induced by cytotoxic T lymphocytes from perforin-deficient mice: a major role for inositol 1,4,5-trisphosphate.
Volume: 82
Issue: 4
Pages: 438-50
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Publication
11559824 | J:71576
First Author: Aung S
Year: 2001
Journal: J Virol
Title: Alternative mechanisms of respiratory syncytial virus clearance in perforin knockout mice lead to enhanced disease.
Volume: 75
Issue: 20
Pages: 9918-24
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Publication
29293660 | J:291873
First Author: Schmidt ME
Year: 2018
Journal: PLoS Pathog
Title: Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection.
Volume: 14
Issue: 1
Pages: e1006810
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Publication
28137589 | J:251239
First Author: Peng SP
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Participation of perforin in mediating dopaminergic neuron loss in MPTP-induced Parkinson's disease in mice.
Volume: 484
Issue: 3
Pages: 618-622
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Publication
12705850 | J:83010
First Author: Badovinac VP
Year: 2003
Journal: Immunity
Title: Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice.
Volume: 18
Issue: 4
Pages: 463-74
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Publication
9708802 | J:106615
First Author: Gebhard JR
Year: 1998
Journal: Am J Pathol
Title: Coxsackievirus B3-induced myocarditis: perforin exacerbates disease, but plays no detectable role in virus clearance.
Volume: 153
Issue: 2
Pages: 417-28
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Publication
9551927 | J:45180
First Author: White DW
Year: 1998
Journal: J Immunol
Title: Perforin-deficient CD8+ T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-gamma but requires TNF-alpha.
Volume: 160
Issue: 2
Pages: 898-905
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Publication
12084043 | J:118412
First Author: Henriques-Pons A
Year: 2002
Journal: Int J Exp Pathol
Title: Evidence for a perforin-mediated mechanism controlling cardiac inflammation in Trypanosoma cruzi infection.
Volume: 83
Issue: 2
Pages: 67-79
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Publication
9681998 | J:114193
First Author: Sambhara S
Year: 1998
Journal: Cell Immunol
Title: Enhanced antibody and cytokine responses to influenza viral antigens in perforin-deficient mice.
Volume: 187
Issue: 1
Pages: 13-8
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Publication
31301754 | J:282085
First Author: Tiwari A
Year: 2019
Journal: Am J Pathol
Title: Penetration of CD8+ Cytotoxic T Cells into Large Target, Tissue Cysts of Toxoplasma gondii, Leads to Its Elimination.
Volume: 189
Issue: 8
Pages: 1594-1607
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Publication
7608538 | J:26759
First Author: Liu CC
Year: 1995
Journal: J Immunol
Title: Morphologic and functional characterization of perforin-deficient lymphokine-activated killer cells.
Volume: 155
Issue: 2
Pages: 602-8
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Publication
22678903 | J:187759
First Author: Pham NL
Year: 2012
Journal: Eur J Immunol
Title: Epitope specificity of memory CD8+ T cells dictates vaccination-induced mortality in LCMV-infected perforin-deficient mice.
Volume: 42
Issue: 6
Pages: 1488-99
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Publication
7972104 | J:21731
First Author: Lowin B
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity.
Volume: 91
Issue: 24
Pages: 11571-5
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Publication
16997856 | J:116571
First Author: Joshi PS
Year: 2006
Journal: J Leukoc Biol
Title: Cytokine-induced killer T cells kill immature dendritic cells by TCR-independent and perforin-dependent mechanisms.
Volume: 80
Issue: 6
Pages: 1345-53
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Publication
25337791 | J:223546
First Author: Johnson HL
Year: 2014
Journal: PLoS One
Title: Perforin competent CD8 T cells are sufficient to cause immune-mediated blood-brain barrier disruption.
Volume: 9
Issue: 10
Pages: e111401
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Publication
11433343 | J:134010
First Author: Ciurea A
Year: 2001
Journal: Nat Med
Title: CD4+ T-cell-epitope escape mutant virus selected in vivo.
Volume: 7
Issue: 7
Pages: 795-800
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Publication
22905147 | J:189906
First Author: Ip CW
Year: 2012
Journal: PLoS One
Title: Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse.
Volume: 7
Issue: 8
Pages: e42554
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Publication
- | J:216044
     
First Author: Zhang D
Year: 2014
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for prime. Updated on December 15, 2014.
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Publication
34262436 | J:322580
 
First Author: Pan Y
Year: 2021
Journal: Front Cell Neurosci
Title: Inhibition of Perforin-Mediated Neurotoxicity Attenuates Neurological Deficits After Ischemic Stroke.
Volume: 15
Pages: 664312
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Publication
11160245 | J:67094
First Author: Zhou P
Year: 2001
Journal: J Immunol
Title: Perforin is required for primary immunity to Histoplasma capsulatum.
Volume: 166
Issue: 3
Pages: 1968-74
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Publication
19264954 | J:149764
First Author: Kuhla A
Year: 2009
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Role of the perforin/granzyme cell death pathway in D-Gal/LPS-induced inflammatory liver injury.
Volume: 296
Issue: 5
Pages: G1069-76
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Publication
20008293 | J:159407
First Author: Suidan GL
Year: 2010
Journal: J Immunol
Title: CD8 T cell-initiated vascular endothelial growth factor expression promotes central nervous system vascular permeability under neuroinflammatory conditions.
Volume: 184
Issue: 2
Pages: 1031-40
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Publication
21357263 | J:170697
First Author: Holst PJ
Year: 2011
Journal: J Immunol
Title: Vaccination against lymphocytic choriomeningitis virus infection in MHC class II-deficient mice.
Volume: 186
Issue: 7
Pages: 3997-4007
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Publication
11907109 | J:75575
First Author: Seki N
Year: 2002
Journal: J Immunol
Title: Tumor-specific CTL kill murine renal cancer cells using both perforin and Fas ligand-mediated lysis in vitro, but cause tumor regression in vivo in the absence of perforin.
Volume: 168
Issue: 7
Pages: 3484-92
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Publication
23691028 | J:200853
First Author: Johnson RM
Year: 2013
Journal: PLoS One
Title: Perforin is detrimental to controlling [corrected] C. muridarum replication in vitro, but not in vivo.
Volume: 8
Issue: 5
Pages: e63340
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Publication
9314549 | J:43468
First Author: Kägi D
Year: 1997
Journal: J Exp Med
Title: Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice.
Volume: 186
Issue: 7
Pages: 989-97
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Publication
22237627 | J:181494
First Author: Doloff JC
Year: 2012
Journal: Cancer Res
Title: VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression.
Volume: 72
Issue: 5
Pages: 1103-15
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Publication
9916752 | J:124760
First Author: Spaner D
Year: 1999
Journal: J Immunol
Title: A role for perforin in activation-induced T cell death in vivo: increased expansion of allogeneic perforin-deficient T cells in SCID mice.
Volume: 162
Issue: 2
Pages: 1192-9
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Publication
29420734 | J:261421
First Author: Schulert GS
Year: 2018
Journal: Int Immunol
Title: Convergent pathways of the hyperferritinemic syndromes.
Volume: 30
Issue: 5
Pages: 195-203
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Publication
23660960 | J:200959
First Author: Terrell CE
Year: 2013
Journal: Blood
Title: Perforin deficiency impairs a critical immunoregulatory loop involving murine CD8(+) T cells and dendritic cells.
Volume: 121
Issue: 26
Pages: 5184-91
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Publication
19216020 | J:146840
First Author: Sarcon AK
Year: 2009
Journal: Exp Hematol
Title: Role of perforin-mediated cell apoptosis in murine models of infusion-induced bone marrow failure.
Volume: 37
Issue: 4
Pages: 477-86
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Publication
36124553 | J:329868
   
First Author: Gutwillig A
Year: 2022
Journal: Elife
Title: Transient cell-in-cell formation underlies tumor relapse and resistance to immunotherapy.
Volume: 11
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Publication
22851709 | J:189856
First Author: Zhang T
Year: 2012
Journal: J Immunol
Title: An NKp30-based chimeric antigen receptor promotes T cell effector functions and antitumor efficacy in vivo.
Volume: 189
Issue: 5
Pages: 2290-9
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Publication
26825707 | J:232632
First Author: Das R
Year: 2016
Journal: Blood
Title: Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis.
Volume: 127
Issue: 13
Pages: 1666-75
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Publication
26752517 | J:233152
First Author: Dotiwala F
Year: 2016
Journal: Nat Med
Title: Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites.
Volume: 22
Issue: 2
Pages: 210-6
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Publication
12668139 | J:119311
First Author: Liu B
Year: 2003
Journal: Microb Pathog
Title: Local immune responses to influenza virus infection in mice with a targeted disruption of perforin gene.
Volume: 34
Issue: 4
Pages: 161-7
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Publication
10430631 | J:56787
First Author: Cretney E
Year: 1999
Journal: J Exp Med
Title: m144, a murine cytomegalovirus (MCMV)-encoded major histocompatibility complex class I homologue, confers tumor resistance to natural killer cell-mediated rejection.
Volume: 190
Issue: 3
Pages: 435-44
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Publication
32530039 | J:304774
First Author: Meyer LK
Year: 2020
Journal: Blood
Title: JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation.
Volume: 136
Issue: 6
Pages: 657-668
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Publication
24658838 | J:211842
First Author: Frese-Schaper M
Year: 2014
Journal: Cancer Immunol Immunother
Title: Influence of natural killer cells and perforin‑mediated cytolysis on the development of chemically induced lung cancer in A/J mice.
Volume: 63
Issue: 6
Pages: 571-80
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Publication
24043891 | J:206269
First Author: Jensen S
Year: 2013
Journal: J Immunol
Title: Adenovirus-based vaccine against Listeria monocytogenes: extending the concept of invariant chain linkage.
Volume: 191
Issue: 8
Pages: 4152-64
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Publication
31572388 | J:281848
 
First Author: Cuff AO
Year: 2019
Journal: Front Immunol
Title: The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype.
Volume: 10
Pages: 2180
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Publication
11438167 | J:102966
First Author: Palma JP
Year: 2001
Journal: J Neuroimmunol
Title: Enhanced susceptibility to Theiler's virus-induced demyelinating disease in perforin-deficient mice.
Volume: 116
Issue: 2
Pages: 125-35
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Publication
16373503 | J:104557
First Author: Yang J
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Perforin-dependent elimination of dendritic cells regulates the expansion of antigen-specific CD8+ T cells in vivo.
Volume: 103
Issue: 1
Pages: 147-52
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Publication
22751116 | J:197226
First Author: Sagiv A
Year: 2013
Journal: Oncogene
Title: Granule exocytosis mediates immune surveillance of senescent cells.
Volume: 32
Issue: 15
Pages: 1971-7
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