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Search results 1 to 100 out of 105 for Primpol

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: PRIMPOL has both DNA polymerase and DNA/RNA primase activities. It is involved in downstream repriming of stalled forks during both nuclear and mitochondrial DNA replication. It pays an important part in DNA damage tolerance []. It is predicted to possess an archaeo-eukaryotic primase and a UL52-like zinc finger domain [, ]. The primase activity of PRIMPOL is essential for many functions in the nucleus. However, the role of PRIMPOL polymerase activity is still unclear, as PRIMPOL synthesizes DNA with limited processivity, rarely incorporating more than four nucleotides on an undamaged template [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Tirman S
Year: 2021
Journal: Crit Rev Biochem Mol Biol
Title: PRIMPOL ready, set, reprime!
Volume: 56
Issue: 1
Pages: 17-30
Publication
First Author: Pilzecker B
Year: 2016
Journal: Nucleic Acids Res
Title: PrimPol prevents APOBEC/AID family mediated DNA mutagenesis.
Volume: 44
Issue: 10
Pages: 4734-44
Publication
First Author: Bianchi J
Year: 2013
Journal: Mol Cell
Title: PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication.
Volume: 52
Issue: 4
Pages: 566-73
Publication
First Author: Torregrosa-Muñumer R
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: PrimPol is required for replication reinitiation after mtDNA damage.
Volume: 114
Issue: 43
Pages: 11398-11403
Protein
Organism: Mus musculus/domesticus
Length: 537  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 265  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 114  
Fragment?: true
Publication
First Author: Rechkoblit O
Year: 2016
Journal: Sci Adv
Title: Structure and mechanism of human PrimPol, a DNA polymerase with primase activity.
Volume: 2
Issue: 10
Pages: e1601317
Publication
First Author: Keen BA
Year: 2014
Journal: Nucleic Acids Res
Title: Molecular dissection of the domain architecture and catalytic activities of human PrimPol.
Volume: 42
Issue: 9
Pages: 5830-45
Publication
First Author: Quinet A
Year: 2021
Journal: Mol Cell
Title: To skip or not to skip: choosing repriming to tolerate DNA damage.
Volume: 81
Issue: 4
Pages: 649-658
Publication
First Author: GarcĂ­a-GĂłmez S
Year: 2013
Journal: Mol Cell
Title: PrimPol, an archaic primase/polymerase operating in human cells.
Volume: 52
Issue: 4
Pages: 541-53
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218641
Specimen Label: MRC Harwell_218641
Detected: true
Specimen Num: 7
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218649
Note: kidney
Specimen Label: MRC Harwell_218649
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1666528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218653
Specimen Label: MRC Harwell_218653
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218641
Specimen Label: MRC Harwell_218641
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218641
Specimen Label: MRC Harwell_218641
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218643
Specimen Label: MRC Harwell_218643
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1898428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218651
Specimen Label: MRC Harwell_218651
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1753628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218641
Specimen Label: MRC Harwell_218641
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218641
Specimen Label: MRC Harwell_218641
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218641
Specimen Label: MRC Harwell_218641
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218643
Specimen Label: MRC Harwell_218643
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3278228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218657
Specimen Label: MRC Harwell_218657
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218641
Specimen Label: MRC Harwell_218641
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218643
Specimen Label: MRC Harwell_218643
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218645
Specimen Label: MRC Harwell_218645
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1860128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218645
Specimen Label: MRC Harwell_218645
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1842628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218647
Specimen Label: MRC Harwell_218647
Detected: true
Specimen Num: 10
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218655
Specimen Label: MRC Harwell_218655
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218635
Specimen Label: MRC Harwell_218635
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218653
Specimen Label: MRC Harwell_218653
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218659
Specimen Label: MRC Harwell_218659
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218655
Specimen Label: MRC Harwell_218655
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218657
Specimen Label: MRC Harwell_218657
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218655
Specimen Label: MRC Harwell_218655
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218651
Specimen Label: MRC Harwell_218651
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218641
Specimen Label: MRC Harwell_218641
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218643
Specimen Label: MRC Harwell_218643
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692917
Age: postnatal adult
Image: MRC Harwell_218651
Specimen Label: MRC Harwell_218651
Detected: true
Specimen Num: 1
Publication
First Author: Probert F
Year: 2015
Journal: J Proteome Res
Title: ÂąH NMR metabolic profiling of plasma reveals additional phenotypes in knockout mouse models.
Volume: 14
Issue: 5
Pages: 2036-45
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference