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Search results 1 to 100 out of 928 for Prkca

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rabbit, European
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
GXD Expression
Probe: MGI:6450091
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6450188
Age: postnatal month 2-3
Image: 3P
Note: Prkca labels rod bipolar cells. Prkca does not co-label with Irx6: b-gal positive bipolar cells.
Specimen Label: 3P
Detected: true
Specimen Num: 1
Publication
First Author: Cataisson C
Year: 2003
Journal: J Immunol
Title: Activation of cutaneous protein kinase C alpha induces keratinocyte apoptosis and intraepidermal inflammation by independent signaling pathways.
Volume: 171
Issue: 5
Pages: 2703-13
Publication
First Author: Hambleton M
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Inducible and myocyte-specific inhibition of PKCalpha enhances cardiac contractility and protects against infarction-induced heart failure.
Volume: 293
Issue: 6
Pages: H3768-71
Publication
First Author: Braz JC
Year: 2004
Journal: Nat Med
Title: PKC-alpha regulates cardiac contractility and propensity toward heart failure.
Volume: 10
Issue: 3
Pages: 248-54
Publication
First Author: Jakubcakova V
Year: 2007
Journal: Neuron
Title: Light entrainment of the mammalian circadian clock by a PRKCA-dependent posttranslational mechanism.
Volume: 54
Issue: 5
Pages: 831-43
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Publication
First Author: Cataisson C
Year: 2005
Journal: J Immunol
Title: Protein kinase C alpha-mediated chemotaxis of neutrophils requires NF-kappa B activity but is independent of TNF alpha signaling in mouse skin in vivo.
Volume: 174
Issue: 3
Pages: 1686-92
Publication
First Author: Alfonso SI
Year: 2016
Journal: Sci Signal
Title: Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer's disease.
Volume: 9
Issue: 427
Pages: ra47
Publication
First Author: Hara T
Year: 2002
Journal: Gene
Title: Genomic organization and chromosomal localization of the mouse protein kinase C alpha gene.
Volume: 291
Issue: 1-2
Pages: 11-6
Publication
First Author: Nicod J
Year: 2016
Journal: Nat Genet
Title: Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing.
Volume: 48
Issue: 8
Pages: 912-8
Publication  
First Author: Wang F
Year: 2017
Journal: Nat Commun
Title: Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancy.
Volume: 8
Pages: 15182
Publication
First Author: Jansen AP
Year: 2001
Journal: Int J Cancer
Title: Relation of the induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C alpha, -delta and -epsilon transgenic mice.
Volume: 93
Issue: 5
Pages: 635-43
Publication
First Author: Staudinger J
Year: 1995
Journal: J Cell Biol
Title: PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system.
Volume: 128
Issue: 3
Pages: 263-71
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Rose-John S
Year: 1988
Journal: Gene
Title: Molecular cloning of mouse protein kinase C (PKC) cDNA from Swiss 3T3 fibroblasts.
Volume: 74
Issue: 2
Pages: 465-71
Publication
First Author: Megidish T
Year: 1989
Journal: Nature
Title: A mutant protein kinase C that can transform fibroblasts.
Volume: 342
Issue: 6251
Pages: 807-11
Publication
First Author: Pierce A
Year: 1998
Journal: J Cell Biol
Title: An activated protein kinase C alpha gives a differentiation signal for hematopoietic progenitor cells and mimicks macrophage colony-stimulating factor-stimulated signaling events.
Volume: 140
Issue: 6
Pages: 1511-8
Publication
First Author: Konopatskaya O
Year: 2009
Journal: J Clin Invest
Title: PKCalpha regulates platelet granule secretion and thrombus formation in mice.
Volume: 119
Issue: 2
Pages: 399-407
Publication
First Author: Dwyer-Nield LD
Year: 2000
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Quantitative trait locus mapping of genes regulating pulmonary PKC activity and PKC-alpha content.
Volume: 279
Issue: 2
Pages: L326-32
Publication
First Author: Bao HF
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: ENaC activity is increased in isolated, split-open cortical collecting ducts from protein kinase Cα knockout mice.
Volume: 306
Issue: 3
Pages: F309-20
Publication
First Author: Wynne BM
Year: 2018
Journal: J Hypertens
Title: Protein kinase Cα deletion causes hypotension and decreased vascular contractility.
Volume: 36
Issue: 3
Pages: 510-519
Publication
First Author: Nieves-Cintrón M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension.
Volume: 105
Issue: 40
Pages: 15623-8
Publication
First Author: Thai TL
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Lack of protein kinase C-α leads to impaired urine concentrating ability and decreased aquaporin-2 in angiotensin II-induced hypertension.
Volume: 303
Issue: 1
Pages: F37-44
Publication
First Author: Eaton AF
Year: 2014
Journal: Am J Physiol Lung Cell Mol Physiol
Title: ENaC activity and expression is decreased in the lungs of protein kinase C-α knockout mice.
Volume: 307
Issue: 5
Pages: L374-85
Publication
First Author: Nowak G
Year: 2020
Journal: FEBS J
Title: Protein kinase Cα mediates recovery of renal and mitochondrial functions following acute injury.
Volume: 287
Issue: 9
Pages: 1830-1849
Publication
First Author: Sim JH
Year: 2014
Journal: PLoS One
Title: Absence of PKC-alpha attenuates lithium-induced nephrogenic diabetes insipidus.
Volume: 9
Issue: 7
Pages: e101753
Publication
First Author: Wang Y
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Role of protein kinase C-α in hypertonicity-stimulated urea permeability in mouse inner medullary collecting ducts.
Volume: 304
Issue: 2
Pages: F233-8
Publication
First Author: Klein JD
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Protein kinase C-α mediates hypertonicity-stimulated increase in urea transporter phosphorylation in the inner medullary collecting duct.
Volume: 302
Issue: 9
Pages: F1098-103
Publication
First Author: Navedo MF
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: Elevated Ca2+ sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells.
Volume: 298
Issue: 2
Pages: C211-20
Publication
First Author: Galea GL
Year: 2014
Journal: J Biol Chem
Title: Protein kinase Cα (PKCα) regulates bone architecture and osteoblast activity.
Volume: 289
Issue: 37
Pages: 25509-22
Publication
First Author: Nowak G
Year: 2015
Journal: J Biol Chem
Title: Protein kinase C-α interaction with F0F1-ATPase promotes F0F1-ATPase activity and reduces energy deficits in injured renal cells.
Volume: 290
Issue: 11
Pages: 7054-66
Publication
First Author: Leitges M
Year: 2002
Journal: Mol Endocrinol
Title: Knockout of PKC alpha enhances insulin signaling through PI3K.
Volume: 16
Issue: 4
Pages: 847-58
Publication
First Author: Chen Z
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Altered morphology and function of the lacrimal functional unit in protein kinase C{alpha} knockout mice.
Volume: 51
Issue: 11
Pages: 5592-600
Publication
First Author: Yao L
Year: 2004
Journal: Am J Physiol Renal Physiol
Title: Evidence for a role of protein kinase C-alpha in urine concentration.
Volume: 287
Issue: 2
Pages: F299-304
Publication
First Author: Ruether K
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: PKC{alpha} is essential for the proper activation and termination of rod bipolar cell response.
Volume: 51
Issue: 11
Pages: 6051-8
Publication
First Author: Thomason HA
Year: 2012
Journal: J Pathol
Title: Direct evidence that PKCα positively regulates wound re-epithelialization: correlation with changes in desmosomal adhesiveness.
Volume: 227
Issue: 3
Pages: 346-56
Publication
First Author: Jensen TE
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Knockout of the predominant conventional PKC isoform, PKCalpha, in mouse skeletal muscle does not affect contraction-stimulated glucose uptake.
Volume: 297
Issue: 2
Pages: E340-8
Publication
First Author: Pfeifhofer C
Year: 2006
Journal: J Immunol
Title: Defective IgG2a/2b class switching in PKC alpha-/- mice.
Volume: 176
Issue: 10
Pages: 6004-11
Publication
First Author: Menne J
Year: 2004
Journal: Diabetes
Title: Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice.
Volume: 53
Issue: 8
Pages: 2101-9
Publication
First Author: Cooper NH
Year: 2015
Journal: J Invest Dermatol
Title: Global Gene Expression Analysis in PKCα-/- Mouse Skin Reveals Structural Changes in the Dermis and Defective Wound Granulation Tissue.
Volume: 135
Issue: 12
Pages: 3173-3182
Publication
First Author: Hara T
Year: 2005
Journal: Cancer Res
Title: Deficiency of protein kinase Calpha in mice results in impairment of epidermal hyperplasia and enhancement of tumor formation in two-stage skin carcinogenesis.
Volume: 65
Issue: 16
Pages: 7356-62
Publication
First Author: Hara T
Year: 2012
Journal: Anticancer Res
Title: PKCα suppresses 7,12-dimethylbenz[a]anthracene-induced skin tumor formation.
Volume: 32
Issue: 8
Pages: 3097-101
Publication
First Author: Hardy SP
Year: 1995
Journal: EMBO J
Title: Protein kinase C-mediated phosphorylation of the human multidrug resistance P-glycoprotein regulates cell volume-activated chloride channels.
Volume: 14
Issue: 1
Pages: 68-75
Publication
First Author: Passos GF
Year: 2013
Journal: Eur J Pharmacol
Title: The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice.
Volume: 698
Issue: 1-3
Pages: 413-20
Publication
First Author: Yang Y
Year: 2013
Journal: PLoS One
Title: The C-terminal V5 domain of Protein Kinase Cα is intrinsically disordered, with propensity to associate with a membrane mimetic.
Volume: 8
Issue: 6
Pages: e65699
Publication  
First Author: Wang HQ
Year: 1999
Journal: J Cell Sci
Title: Overexpression of protein kinase C-alpha in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-alpha expression but not tumor promotion.
Volume: 112 ( Pt 20)
Pages: 3497-506
Publication
First Author: Dean NM
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides.
Volume: 91
Issue: 24
Pages: 11762-6
Publication
First Author: Dlugosz AA
Year: 1994
Journal: Cancer Res
Title: Alterations in murine keratinocyte differentiation induced by activated rasHa genes are mediated by protein kinase C-alpha.
Volume: 54
Issue: 24
Pages: 6413-20
Publication
First Author: Rutberg SE
Year: 1996
Journal: Oncogene
Title: Differentiation of mouse keratinocytes is accompanied by PKC-dependent changes in AP-1 proteins.
Volume: 13
Issue: 1
Pages: 167-76
Publication
First Author: Shishodia S
Year: 1998
Journal: Immunol Lett
Title: Protein kinase C: a potential pathway of macrophage activation with cisplatin.
Volume: 61
Issue: 2-3
Pages: 179-86
Publication
First Author: Quittau-Prévostel C
Year: 2004
Journal: J Cell Sci
Title: Targeting of PKCalpha and epsilon in the pituitary: a highly regulated mechanism involving a GD(E)E motif of the V3 region.
Volume: 117
Issue: Pt 1
Pages: 63-72
Publication
First Author: Cipok M
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Protein kinase Calpha regulates insulin receptor signaling in skeletal muscle.
Volume: 345
Issue: 2
Pages: 817-24
Publication
First Author: Wang Y
Year: 2006
Journal: Biochem Pharmacol
Title: Modulation of mitochondrial metabolic function by phorbol 12-myristate 13-acetate through increased mitochondrial translocation of protein kinase Calpha in C2C12 myocytes.
Volume: 72
Issue: 7
Pages: 881-92
Publication
First Author: Son H
Year: 2006
Journal: Arch Biochem Biophys
Title: Protein kinase Calpha can undergo membrane localization via an alternative phosphatidylinositol 4,5-bisphosphate-dependent pathway.
Volume: 454
Issue: 1
Pages: 1-6
Publication
First Author: Hambleton M
Year: 2006
Journal: Circulation
Title: Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure.
Volume: 114
Issue: 6
Pages: 574-82
Publication
First Author: Lee B
Year: 2007
Journal: Eur J Neurosci
Title: Protein kinase C modulates the phase-delaying effects of light in the mammalian circadian clock.
Volume: 26
Issue: 2
Pages: 451-62
Publication
First Author: Hahn HS
Year: 2003
Journal: Circ Res
Title: Protein kinase Calpha negatively regulates systolic and diastolic function in pathological hypertrophy.
Volume: 93
Issue: 11
Pages: 1111-9
Publication
First Author: Dong C
Year: 2009
Journal: Neuroscience
Title: Protein kinase Calpha mediates a novel form of plasticity in the accessory olfactory bulb.
Volume: 163
Issue: 3
Pages: 811-24
Publication
First Author: Yang L
Year: 2010
Journal: Biochem Biophys Res Commun
Title: TCR-induced Akt serine 473 phosphorylation is regulated by protein kinase C-alpha.
Volume: 400
Issue: 1
Pages: 16-20
Publication
First Author: Nakura A
Year: 2011
Journal: Bone
Title: PKCα suppresses osteoblastic differentiation.
Volume: 48
Issue: 3
Pages: 476-84
GXD Expression    
Probe: MGI:1204474
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3514028
Stage: TS28
Assay Id: MGI:1204476
Age: postnatal week 6-8
Image: st96_177
Specimen Label: None
Detected: true
Specimen Num: 37
GXD Expression    
Probe: MGI:1205626
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3514028
Stage: TS28
Assay Id: MGI:1205628
Age: postnatal week 6-8
Image: st97_604
Specimen Label: None
Detected: true
Specimen Num: 37
GXD Expression    
Probe: MGI:1204474
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1204476
Age: postnatal week 6-8
Image: st96_177
Specimen Label: None
Detected: true
Specimen Num: 14