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Search results 1 to 100 out of 627 for Prkcd

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
5580 | PRKCD
Type: gene
Organism: human
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Gene
733756 | prkcd
Type: gene
Organism: frog, western clawed
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Gene
170538 | Prkcd
Type: gene
Organism: rat
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Gene
494005 | PRKCD
Type: gene
Organism: dog, domestic
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Gene
460442 | PRKCD
Type: gene
Organism: chimpanzee
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Gene
505708 | PRKCD
Type: gene
Organism: cattle
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Gene
415905 | PRKCD
Type: gene
Organism: chicken
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Gene
694656 | PRKCD
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:97598 | Prkcd
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:6181283
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191142
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Prkcd
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6181283
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191142
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Prkcd
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6181283
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191142
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Prkcd
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6181283
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191142
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Prkcd
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6181283
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191142
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Prkcd
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6181283
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191142
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Prkcd
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6181283
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191142
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Prkcd
Detected: true
Specimen Num: 6
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Protein
Q80UN7
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
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Publication
- | J:265145
     
First Author: Turer E
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Rigged.
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Publication
- | J:265146
     
First Author: Turer E
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for rigged2.
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Publication
10582689 | J:58557
First Author: Reddig PJ
Year: 1999
Journal: Cancer Res
Title: Transgenic mice overexpressing protein kinase Cdelta in the epidermis are resistant to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Volume: 59
Issue: 22
Pages: 5710-8
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Publication
36961448 | J:353352
First Author: Moreews M
Year: 2023
Journal: J Immunol
Title: mTOR Activation Underlies Enhanced B Cell Proliferation and Autoimmunity in PrkcdG510S/G510S Mice.
Volume: 210
Issue: 9
Pages: 1209-1221
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Publication
12032864 | J:76748
First Author: Wheeler DL
Year: 2002
Journal: Oncogene
Title: Protein kinase Cdelta-mediated signal to ornithine decarboxylase induction is independent of skin tumor suppression.
Volume: 21
Issue: 22
Pages: 3620-30
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Publication
21103982 | J:166437
First Author: Cantley J
Year: 2011
Journal: Diabetologia
Title: Deletion of protein kinase Cδ in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo.
Volume: 54
Issue: 2
Pages: 380-9
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Publication
37890601 | J:342376
 
First Author: Singh G
Year: 2024
Journal: Gene
Title: Loss of PKCδ/Prkcd prevents cartilage degeneration in joints but exacerbates hyperalgesia in an experimental osteoarthritis mouse model.
Volume: 893
Pages: 147920
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Publication
21576825 | J:173902
First Author: Bezy O
Year: 2011
Journal: J Clin Invest
Title: PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans.
Volume: 121
Issue: 6
Pages: 2504-17
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Publication
25253077 | J:230185
First Author: Szilagyi K
Year: 2014
Journal: Cardiovasc Res
Title: PKCδ is dispensible for oxLDL uptake and foam cell formation by human and murine macrophages.
Volume: 104
Issue: 3
Pages: 467-76
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Publication
22885697 | J:189256
First Author: Qu Y
Year: 2012
Journal: Nature
Title: Phosphorylation of NLRC4 is critical for inflammasome activation.
Volume: 490
Issue: 7421
Pages: 539-42
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Publication
16424000 | J:106470
First Author: Aziz MH
Year: 2006
Journal: Cancer Res
Title: Protein kinase C delta overexpressing transgenic mice are resistant to chemically but not to UV radiation-induced development of squamous cell carcinomas: a possible link to specific cytokines and cyclooxygenase-2.
Volume: 66
Issue: 2
Pages: 713-22
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Protein Coding Gene
MGP_CAROLIEiJ_G0019052 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021053 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021030 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021057 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020840 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97598 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021489 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020365 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020807 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020929 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020913 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020998 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020939 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021522 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020420 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030069 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019937 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1868068 | J:11370
First Author: Mischak H
Year: 1991
Journal: Biochemistry
Title: Mouse protein kinase C-delta, the major isoform expressed in mouse hemopoietic cells: sequence of the cDNA, expression patterns, and characterization of the protein.
Volume: 30
Issue: 32
Pages: 7925-31
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Publication
1765103 | J:2328
First Author: Mizuno K
Year: 1991
Journal: Eur J Biochem
Title: Structure and properties of a ubiquitously expressed protein kinase C, nPKC delta.
Volume: 202
Issue: 3
Pages: 931-40
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Publication
11976686 | J:76134
First Author: Mecklenbräuker I
Year: 2002
Journal: Nature
Title: Protein kinase Cdelta controls self-antigen-induced B-cell tolerance.
Volume: 416
Issue: 6883
Pages: 860-5
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Publication
18025218 | J:155211
First Author: Cheng N
Year: 2007
Journal: J Immunol
Title: A critical role of protein kinase C delta activation loop phosphorylation in formyl-methionyl-leucyl-phenylalanine-induced phosphorylation of p47(phox) and rapid activation of nicotinamide adenine dinucleotide phosphate oxidase.
Volume: 179
Issue: 11
Pages: 7720-8
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Publication
16638571 | J:108430
First Author: Kawaguchi T
Year: 2006
Journal: FEBS Lett
Title: New PKCdelta family members, PKCdeltaIV, deltaV, deltaVI, and deltaVII are specifically expressed in mouse testis.
Volume: 580
Issue: 10
Pages: 2458-64
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Publication
12826574 | J:86146
First Author: Viveiros MM
Year: 2003
Journal: Biol Reprod
Title: Characterization of protein kinase C-delta in mouse oocytes throughout meiotic maturation and following egg activation.
Volume: 69
Issue: 5
Pages: 1494-9
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Publication
23474764 | J:212377
First Author: Allen-Petersen BL
Year: 2014
Journal: Oncogene
Title: Protein kinase Cδ is required for ErbB2-driven mammary gland tumorigenesis and negatively correlates with prognosis in human breast cancer.
Volume: 33
Issue: 10
Pages: 1306-15
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Publication
24357731 | J:208697
First Author: Zheng Y
Year: 2014
Journal: Blood
Title: B-cell tolerance regulates production of antibodies causing heparin-induced thrombocytopenia.
Volume: 123
Issue: 6
Pages: 931-4
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Publication
26708502 | J:230581
 
First Author: Ganesan S
Year: 2016
Journal: Toxicol Appl Pharmacol
Title: The ovarian DNA damage repair response is induced prior to phosphoramide mustard-induced follicle depletion, and ataxia telangiectasia mutated inhibition prevents PM-induced follicle depletion.
Volume: 292
Pages: 65-74
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Publication
19808702 | J:172551
First Author: Yamanouchi D
Year: 2010
Journal: Cardiovasc Res
Title: Protein kinase C delta mediates arterial injury responses through regulation of vascular smooth muscle cell apoptosis.
Volume: 85
Issue: 3
Pages: 434-43
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Publication
30679314 | J:276809
First Author: Ohm AM
Year: 2019
Journal: J Biol Chem
Title: EGF receptor and PKCδ kinase activate DNA damage-induced pro-survival and pro-apoptotic signaling via biphasic activation of ERK and MSK1 kinases.
Volume: 294
Issue: 12
Pages: 4488-4497
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Publication
25342743 | J:315831
First Author: Jin H
Year: 2014
Journal: J Biol Chem
Title: Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease.
Volume: 289
Issue: 50
Pages: 34743-67
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Publication
23951014 | J:205893
First Author: Khor EC
Year: 2013
Journal: PLoS One
Title: Loss of protein kinase C-δ protects against LPS-induced osteolysis owing to an intrinsic defect in osteoclastic bone resorption.
Volume: 8
Issue: 8
Pages: e70815
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Publication
32142354 | J:291275
First Author: Joseph LC
Year: 2020
Journal: Am J Physiol Heart Circ Physiol
Title: PKCδ causes sepsis-induced cardiomyopathy by inducing mitochondrial dysfunction.
Volume: 318
Issue: 4
Pages: H778-H786
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Publication
17200189 | J:117054
First Author: Shukla A
Year: 2007
Journal: Am J Pathol
Title: Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice.
Volume: 170
Issue: 1
Pages: 140-51
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Publication
17135234 | J:120293
First Author: Uchida T
Year: 2007
Journal: J Biol Chem
Title: Protein kinase Cdelta plays a non-redundant role in insulin secretion in pancreatic beta cells.
Volume: 282
Issue: 4
Pages: 2707-16
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Publication
21732361 | J:347212
First Author: Grinnell K
Year: 2012
Journal: J Cell Physiol
Title: Heterogeneity in apoptotic responses of microvascular endothelial cells to oxidative stress.
Volume: 227
Issue: 5
Pages: 1899-910
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Publication
22463764 | J:208248
First Author: Cao Y
Year: 2012
Journal: J Matern Fetal Neonatal Med
Title: The essential role of protein kinase Cδ in diabetes-induced neural tube defects.
Volume: 25
Issue: 10
Pages: 2020-4
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Publication
19213940 | J:161833
First Author: Chari R
Year: 2009
Journal: Arterioscler Thromb Vasc Biol
Title: Protein kinase C[delta] differentially regulates platelet functional responses.
Volume: 29
Issue: 5
Pages: 699-705
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Publication
26202826 | J:325872
First Author: Ma W
Year: 2015
Journal: Mol Reprod Dev
Title: Lack of protein kinase C-delta (PKCδ) disrupts fertilization and embryonic development.
Volume: 82
Issue: 10
Pages: 797-808
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Publication
19116364 | J:144200
First Author: Buder-Hoffmann SA
Year: 2009
Journal: Am J Pathol
Title: A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos.
Volume: 174
Issue: 2
Pages: 449-59
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Publication
22983354 | J:193660
First Author: Chichger H
Year: 2012
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Genetic disruption of protein kinase Cδ reduces endotoxin-induced lung injury.
Volume: 303
Issue: 10
Pages: L880-8
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Publication
16452485 | J:111584
First Author: Humphries MJ
Year: 2006
Journal: J Biol Chem
Title: Suppression of apoptosis in the protein kinase Cdelta null mouse in vivo.
Volume: 281
Issue: 14
Pages: 9728-37
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Publication
27151770 | J:240848
 
First Author: Gordon R
Year: 2016
Journal: Neurobiol Dis
Title: Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.
Volume: 93
Pages: 96-114
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Publication
26307588 | J:246936
First Author: Li M
Year: 2015
Journal: Diabetes
Title: Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism.
Volume: 64
Issue: 12
Pages: 4023-32
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Publication
11714742 | J:78680
First Author: Leitges M
Year: 2001
Journal: J Clin Invest
Title: Exacerbated vein graft arteriosclerosis in protein kinase Cdelta-null mice.
Volume: 108
Issue: 10
Pages: 1505-12
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Publication
15277209 | J:95583
First Author: Mayr M
Year: 2004
Journal: Am J Physiol Heart Circ Physiol
Title: Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice.
Volume: 287
Issue: 2
Pages: H946-56
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Publication
23557702 | J:208971
First Author: Lizotte F
Year: 2013
Journal: Diabetes
Title: PKCδ impaired vessel formation and angiogenic factor expression in diabetic ischemic limbs.
Volume: 62
Issue: 8
Pages: 2948-57
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Publication
15277208 | J:95584
First Author: Mayr M
Year: 2004
Journal: Am J Physiol Heart Circ Physiol
Title: Loss of PKC-delta alters cardiac metabolism.
Volume: 287
Issue: 2
Pages: H937-45
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Publication
15131007 | J:99169
First Author: Mayr M
Year: 2004
Journal: Circ Res
Title: Proteomic and metabolomic analysis of vascular smooth muscle cells: role of PKCdelta.
Volume: 94
Issue: 10
Pages: e87-96
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Publication
15585335 | J:105091
First Author: Gruber T
Year: 2005
Journal: Immunol Lett
Title: PKCdelta is involved in signal attenuation in CD3+ T cells.
Volume: 96
Issue: 2
Pages: 291-3
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Publication
26671999 | J:230890
First Author: Shabrova E
Year: 2016
Journal: FASEB J
Title: Retinol as a cofactor for PKCδ-mediated impairment of insulin sensitivity in a mouse model of diet-induced obesity.
Volume: 30
Issue: 3
Pages: 1339-55
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Publication
19027023 | J:149182
First Author: Mayr M
Year: 2009
Journal: J Mol Cell Cardiol
Title: Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts.
Volume: 46
Issue: 2
Pages: 268-77
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Publication
28832027 | J:330321
First Author: Parihar SP
Year: 2018
Journal: Mucosal Immunol
Title: Protein kinase C-delta (PKCδ), a marker of inflammation and tuberculosis disease progression in humans, is important for optimal macrophage killing effector functions and survival in mice.
Volume: 11
Issue: 2
Pages: 496-511
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Publication
23305608 | J:193248
 
First Author: Carracedo S
Year: 2013
Journal: BMC Dev Biol
Title: Expression pattern of protein kinase Cδ during mouse embryogenesis.
Volume: 13
Pages: 2
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Publication
39312649 | J:360153
First Author: Lajiness JD
Year: 2024
Journal: J Leukoc Biol
Title: Dendritic cell-specific deletion of PKCδ in offspring of allergic mothers prevents the predisposition for development of allergic lung inflammation in offspring.
Volume: 116
Issue: 6
Pages: 1432-1445
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Publication
15232611 | J:91377
First Author: Chou WH
Year: 2004
Journal: J Clin Invest
Title: Neutrophil protein kinase Cdelta as a mediator of stroke-reperfusion injury.
Volume: 114
Issue: 1
Pages: 49-56
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Publication
19005054 | J:142404
First Author: Choi DS
Year: 2008
Journal: J Neurosci
Title: Protein kinase Cdelta regulates ethanol intoxication and enhancement of GABA-stimulated tonic current.
Volume: 28
Issue: 46
Pages: 11890-9
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Publication
38134280 | J:343766
First Author: Chaib M
Year: 2023
Journal: Sci Adv
Title: Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer.
Volume: 9
Issue: 51
Pages: eadd3231
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Publication
21633170 | J:175662
First Author: Pabla N
Year: 2011
Journal: J Clin Invest
Title: Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer.
Volume: 121
Issue: 7
Pages: 2709-22
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Publication
24454937 | J:212187
First Author: Greene MW
Year: 2014
Journal: PLoS One
Title: Lipid metabolism, oxidative stress and cell death are regulated by PKC delta in a dietary model of nonalcoholic steatohepatitis.
Volume: 9
Issue: 1
Pages: e85848
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Publication
27348590 | J:237130
First Author: He Y
Year: 2016
Journal: J Clin Invest
Title: PKCδ-targeted intervention relieves chronic pain in a murine sickle cell disease model.
Volume: 126
Issue: 8
Pages: 3053-7
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Publication
20395372 | J:185937
First Author: Li X
Year: 2010
Journal: J Am Soc Nephrol
Title: PKC-delta promotes renal tubular cell apoptosis associated with proteinuria.
Volume: 21
Issue: 7
Pages: 1115-24
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Publication
25505183 | J:217880
First Author: Kumar V
Year: 2015
Journal: J Biol Chem
Title: Generation and characterization of ATP analog-specific protein kinase Cδ.
Volume: 290
Issue: 4
Pages: 1936-51
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Publication
34197550 | J:307392
First Author: Niino YS
Year: 2021
Journal: PLoS One
Title: PKCδ deficiency inhibits fetal development and is associated with heart elastic fiber hyperplasia and lung inflammation in adult PKCδ knockout mice.
Volume: 16
Issue: 7
Pages: e0253912
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Publication
14583092 | J:148072
First Author: Greene MW
Year: 2004
Journal: Biochem J
Title: Modulation of human insulin receptor substrate-1 tyrosine phosphorylation by protein kinase Cdelta.
Volume: 378
Issue: Pt 1
Pages: 105-16
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Publication
1477958 | J:3421
First Author: Kim HM
Year: 1992
Journal: Brain Res Dev Brain Res
Title: Localization and developmental expression of a novel protein kinase C delta gene.
Volume: 70
Issue: 2
Pages: 239-44
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Publication
7637094 | J:28857
First Author: Um JY
Year: 1995
Journal: J Urol
Title: Expression of protein kinase C delta gene in germ cells.
Volume: 154
Issue: 3
Pages: 1237-40
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Publication
8526869 | J:30141
 
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Title: Antisense oligodeoxynucleotide inhibition of delta protein kinase C expression accelerates induced differentiation of murine erythroleukaemia cells.
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First Author: Shih NY
Year: 1996
Journal: J Biol Chem
Title: Protein kinase C-delta mRNA is down-regulated transcriptionally and post-transcriptionally by 12-O-tetradecanoylphorbol-13-acetate.
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First Author: Wang QJ
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Journal: J Biol Chem
Title: The catalytic domain of protein kinase C-delta in reciprocal delta and epsilon chimeras mediates phorbol ester-induced macrophage differentiation of mouse promyelocytes.
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First Author: Jackson DN
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Year: 2005
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Title: Diminished PKC activity and decreased binding of transcription factors are involved in the impaired production of nitric oxide by macrophages from tumor-bearing mice.
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