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Search results 1 to 100 out of 1267 for Prkdc

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Type Details Score
Gene
5591 | PRKDC
Type: gene
Organism: human
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Gene
512740 | PRKDC
Type: gene
Organism: cattle
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Gene
395376 | PRKDC
Type: gene
Organism: chicken
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Gene
562283 | prkdc
Type: gene
Organism: zebrafish
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Gene
708029 | PRKDC
Type: gene
Organism: macaque, rhesus
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Gene
100488663 | prkdc
Type: gene
Organism: frog, western clawed
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Gene
key_31098 | PRKDC
Type: gene
Organism: hamster, Chinese
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Gene
key_79388 | PRKDC
Type: gene
Organism: horse
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Gene
360748 | Prkdc
Type: gene
Organism: rat
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Gene
474176 | PRKDC
Type: gene
Organism: dog, domestic
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Gene
464165 | PRKDC
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:104779 | Prkdc
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
21265624 | J:261990
First Author: Fabre KM
Year: 2011
Journal: Radiat Res
Title: Murine Prkdc polymorphisms impact DNA-PKcs function.
Volume: 175
Issue: 4
Pages: 493-500
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Publication
- | J:266856
     
First Author: Peng SY
Year: 2018
Journal: MGI Direct Data Submission
Title: Direct data submission for Prkdc allele.
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Publication
12857942 | J:84988
First Author: Faiola B
Year: 2003
Journal: Toxicol Sci
Title: Variations in Prkdc and susceptibility to benzene-induced toxicity in mice.
Volume: 75
Issue: 2
Pages: 321-32
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Publication
20978358 | J:166909
First Author: Papeta N
Year: 2010
Journal: J Clin Invest
Title: Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice.
Volume: 120
Issue: 11
Pages: 4055-64
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Publication
31950264 | J:310493
First Author: Oliveira CF
Year: 2020
Journal: Cell Tissue Res
Title: Foxn1 and Prkdc genes are important for testis function: evidence from nude and scid adult mice.
Volume: 380
Issue: 3
Pages: 615-625
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Publication
12750252 | J:83496
First Author: Blackburn AC
Year: 2003
Journal: Cancer Res
Title: BALB/c alleles for Prkdc and Cdkn2a interact to modify tumor susceptibility in Trp53+/- mice.
Volume: 63
Issue: 10
Pages: 2364-8
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Publication
11439324 | J:70283
First Author: Mori N
Year: 2001
Journal: Oncogene
Title: Variations in Prkdc encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) and susceptibility to radiation-induced apoptosis and lymphomagenesis.
Volume: 20
Issue: 28
Pages: 3609-19
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Publication
33839407 | J:305297
 
First Author: Watanabe M
Year: 2021
Journal: Biochem Biophys Res Commun
Title: A single amino acid substitution in PRKDC is a determinant of sensitivity to Adriamycin-induced renal injury in mouse.
Volume: 556
Pages: 121-126
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Publication
28686579 | J:269296
First Author: Gurley KE
Year: 2017
Journal: Cell Death Differ
Title: Synergy between Prkdc and Trp53 regulates stem cell proliferation and GI-ARS after irradiation.
Volume: 24
Issue: 11
Pages: 1853-1860
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Publication
11280730 | J:68487
First Author: Yu Y
Year: 2001
Journal: Cancer Res
Title: Elevated breast cancer risk in irradiated BALB/c mice associates with unique functional polymorphism of the Prkdc (DNA-dependent protein kinase catalytic subunit) gene.
Volume: 61
Issue: 5
Pages: 1820-4
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Allele
Prkdc<em5Lutzy> | MGI:6763019
Name: protein kinase, DNA activated, catalytic polypeptide; endonuclease-mediated mutation 5, Cathy Lutz
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
9398856 | J:44390
First Author: Jhappan C
Year: 1997
Journal: Nat Genet
Title: DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus.
Volume: 17
Issue: 4
Pages: 483-6
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Publication
- | J:178522
     
First Author: Beutler B
Year: 2001
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/12/20
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Publication
9861008 | J:108650
First Author: Bogue MA
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation.
Volume: 95
Issue: 26
Pages: 15559-64
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Publication
10805749 | J:108405
First Author: Jhappan C
Year: 2000
Journal: Mol Cell Biol
Title: The p53 response to DNA damage in vivo is independent of DNA-dependent protein kinase.
Volume: 20
Issue: 11
Pages: 4075-83
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Publication
10570295 | J:58652
First Author: Wang C
Year: 1999
Journal: J Immunol
Title: Irradiation-induced rescue of thymocyte differentiation and V(D)J recombination in mice lacking the catalytic subunit of DNA-dependent protein kinase.
Volume: 163
Issue: 11
Pages: 6065-71
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Publication
- | J:224665
     
First Author: Choi JH
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for screamer2
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Publication
24253447 | J:207844
First Author: Sung YH
Year: 2014
Journal: Genome Res
Title: Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
Volume: 24
Issue: 1
Pages: 125-31
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Publication
33273464 | J:299391
First Author: Sun X
Year: 2020
Journal: Nat Commun
Title: DNA-PK deficiency potentiates cGAS-mediated antiviral innate immunity.
Volume: 11
Issue: 1
Pages: 6182
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Publication
37651888 | J:341230
 
First Author: Takagi Y
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Characterization of novel, severely immunodeficient Prkdc(Δex57/Δex57) mice.
Volume: 678
Pages: 193-199
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Publication
- | J:239221
     
First Author: Charles River
Year: 2017
Journal: Scientific info. sheet (http://www.criver.com/files/pdfs/rms/ncg/ncg-mouse-scientific--sheet.aspx)
Title: NOD CRISPR Prkdcil2r Gamma (NCG) Triple-Immunodeficient Mouse Model
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Publication
19664609 | J:157421
 
First Author: Liu J
Year: 2009
Journal: Brain Res
Title: The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation.
Volume: 1296
Pages: 164-75
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Publication
16687486 | J:108789
First Author: Gladdy RA
Year: 2006
Journal: Mol Cancer Res
Title: p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc.
Volume: 4
Issue: 5
Pages: 311-8
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Publication
10337614 | J:54501
First Author: Lund J
Year: 1999
Journal: Mamm Genome
Title: Sequence-ready physical map of the mouse chromosome 16 region with conserved synteny to the human velocardiofacial syndrome region on 22q11.2.
Volume: 10
Issue: 5
Pages: 438-43
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Protein Coding Gene
MGP_CAROLIEiJ_G0020487 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0022552 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0022513 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0022490 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0022518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022285 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_104779 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022254 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022385 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022361 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0022453 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022383 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0022980 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0021554 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021860 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016192 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021382 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15699352 | J:96632
First Author: Zheng Z
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse.
Volume: 102
Issue: 7
Pages: 2502-7
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Publication
9122213 | J:39329
First Author: Araki R
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice.
Volume: 94
Issue: 6
Pages: 2438-43
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Publication
9339376 | J:43493
First Author: Fujimori A
Year: 1997
Journal: Genomics
Title: The murine DNA-PKcs gene consists of 86 exons dispersed in more than 250 kb.
Volume: 45
Issue: 1
Pages: 194-9
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Publication
8881030 | J:37619
First Author: Hamatani K
Year: 1996
Journal: Immunogenetics
Title: Cloning and chromosomal mapping of the mouse DNA-dependent protein kinase gene.
Volume: 45
Issue: 1
Pages: 1-5
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Publication
8816792 | J:35393
First Author: Blunt T
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse.
Volume: 93
Issue: 19
Pages: 10285-90
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Publication
8816463 | J:35350
First Author: Danska JS
Year: 1996
Journal: Mol Cell Biol
Title: Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes.
Volume: 16
Issue: 10
Pages: 5507-17
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Publication
12426399 | J:111398
First Author: Espejel S
Year: 2002
Journal: EMBO J
Title: Functional interaction between DNA-PKcs and telomerase in telomere length maintenance.
Volume: 21
Issue: 22
Pages: 6275-87
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Publication
10910267 | J:93486
First Author: Chen AM
Year: 2000
Journal: Transplantation
Title: Porcine stem cell engraftment and seeding of murine thymus with class II+ cells in mice expressing porcine cytokines: toward tolerance induction across discordant xenogeneic barriers.
Volume: 69
Issue: 12
Pages: 2484-90
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Publication
10809058 | J:94302
First Author: Yang YG
Year: 2000
Journal: Xenotransplantation
Title: Development and analysis of transgenic mice expressing porcine hematopoietic cytokines: a model for achieving durable porcine hematopoietic chimerism across an extensive xenogeneic barrier.
Volume: 7
Issue: 1
Pages: 58-64
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Publication
27777971 | J:290721
First Author: Martin AJ
Year: 2016
Journal: JCI Insight
Title: Anti-coreceptor therapy drives selective T cell egress by suppressing inflammation-dependent chemotactic cues.
Volume: 1
Issue: 17
Pages: e87636
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Publication
9310832 | J:93122
First Author: O'Reilly LA
Year: 1997
Journal: Int Immunol
Title: bcl-2 transgene expression promotes survival and reduces proliferation of CD3-CD4-CD8- T cell progenitors.
Volume: 9
Issue: 9
Pages: 1291-301
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Publication
23747725 | J:204420
First Author: Matsuoka K
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Generation of mouse models for type 1 diabetes by selective depletion of pancreatic beta cells using toxin receptor-mediated cell knockout.
Volume: 436
Issue: 3
Pages: 400-5
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Publication
16861670 | J:112329
First Author: Barthold SW
Year: 2006
Journal: Infect Immun
Title: Antibody-mediated disease remission in the mouse model of lyme borreliosis.
Volume: 74
Issue: 8
Pages: 4817-25
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Publication
10072498 | J:53220
First Author: Livák F
Year: 1999
Journal: J Immunol
Title: Characterization of TCR gene rearrangements during adult murine T cell development.
Volume: 162
Issue: 5
Pages: 2575-80
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Publication
20523894 | J:162921
First Author: Mishra R
Year: 2010
Journal: PLoS Pathog
Title: NK cells and gammadelta T cells mediate resistance to polyomavirus-induced tumors.
Volume: 6
Issue: 5
Pages: e1000924
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Publication
20207228 | J:158983
First Author: Butler JM
Year: 2010
Journal: Cell Stem Cell
Title: Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.
Volume: 6
Issue: 3
Pages: 251-64
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Publication
11869679 | J:132052
First Author: Hugues S
Year: 2002
Journal: Immunity
Title: Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells.
Volume: 16
Issue: 2
Pages: 169-81
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Publication
28238547 | J:256055
First Author: Espuny-Camacho I
Year: 2017
Journal: Neuron
Title: Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Volume: 93
Issue: 5
Pages: 1066-1081.e8
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Publication
16317068 | J:104385
First Author: Turley SJ
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Endocrine self and gut non-self intersect in the pancreatic lymph nodes.
Volume: 102
Issue: 49
Pages: 17729-33
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Publication
11522664 | J:71050
First Author: Serreze DV
Year: 2001
Journal: Diabetes
Title: Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.
Volume: 50
Issue: 9
Pages: 1992-2000
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Publication
15531925 | J:239806
First Author: Zhang YW
Year: 2005
Journal: Oncogene
Title: Enhanced growth of human met-expressing xenografts in a new strain of immunocompromised mice transgenic for human hepatocyte growth factor/scatter factor.
Volume: 24
Issue: 1
Pages: 101-6
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Publication
8094405 | J:111476
First Author: Shores EW
Year: 1993
Journal: J Immunol
Title: Structurally distinct T cell receptor complexes on developmentally distinct T cell populations in severe combined immunodeficiency mice expressing a TCR beta transgene.
Volume: 150
Issue: 4
Pages: 1263-75
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Publication
7751632 | J:25533
First Author: Takahama Y
Year: 1995
Journal: J Immunol
Title: Regulation of early T cell development by the engagement of TCR-beta complex expressed on fetal thymocytes from TCR-beta-transgenic scid mice.
Volume: 154
Issue: 11
Pages: 5862-9
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Publication
12716741 | J:83195
First Author: Pierce MA
Year: 2003
Journal: Diabetes
Title: Adenovirus early region 3 antiapoptotic 10.4K, 14.5K, and 14.7K genes decrease the incidence of autoimmune diabetes in NOD mice.
Volume: 52
Issue: 5
Pages: 1119-27
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Publication
7589844 | J:29951
First Author: Serreze DV
Year: 1995
Journal: Diabetes
Title: Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells.
Volume: 44
Issue: 12
Pages: 1392-8
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Publication
26961115 | J:274578
First Author: Leeth CM
Year: 2016
Journal: Diabetes
Title: B-lymphocytes expressing an Ig specificity recognizing the pancreatic ß-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice.
Volume: 65
Issue: 7
Pages: 1977-1987
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Publication
32938729 | J:300375
First Author: Racine JJ
Year: 2020
Journal: J Immunol
Title: T Cells from NOD-PerIg Mice Target Both Pancreatic and Neuronal Tissue.
Volume: 205
Issue: 8
Pages: 2026-2038
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Publication
15557158 | J:94366
First Author: Alba A
Year: 2004
Journal: J Immunol
Title: IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.
Volume: 173
Issue: 11
Pages: 6667-75
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Publication
9736027 | J:106595
First Author: Stalder AK
Year: 1998
Journal: Am J Pathol
Title: Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor.
Volume: 153
Issue: 3
Pages: 767-83
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Publication
18984741 | J:146982
First Author: Mangada J
Year: 2009
Journal: Diabetes
Title: Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice.
Volume: 58
Issue: 1
Pages: 165-73
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Publication
21169553 | J:168755
First Author: Yang GX
Year: 2011
Journal: J Immunol
Title: CD8 T cells mediate direct biliary ductule damage in nonobese diabetic autoimmune biliary disease.
Volume: 186
Issue: 2
Pages: 1259-67
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Publication
16888083 | J:113033
First Author: Qualls JE
Year: 2006
Journal: J Leukoc Biol
Title: Suppression of experimental colitis by intestinal mononuclear phagocytes.
Volume: 80
Issue: 4
Pages: 802-15
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Publication
9836515 | J:100251
First Author: Bridgett M
Year: 1998
Journal: Diabetes
Title: Differential protection in two transgenic lines of NOD/Lt mice hyperexpressing the autoantigen GAD65 in pancreatic beta-cells.
Volume: 47
Issue: 12
Pages: 1848-56
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Publication
9530156 | J:46553
First Author: Mähler M
Year: 1998
Journal: Am J Physiol
Title: Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis.
Volume: 274
Issue: 3 Pt 1
Pages: G544-51
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Publication
31509739 | J:286169
First Author: Jones RE
Year: 2019
Journal: Cell Rep
Title: Skeletal Stem Cell-Schwann Cell Circuitry in Mandibular Repair.
Volume: 28
Issue: 11
Pages: 2757-2766.e5
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Publication
16622013 | J:131655
First Author: Waldner H
Year: 2006
Journal: J Immunol
Title: The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells.
Volume: 176
Issue: 9
Pages: 5455-62
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Publication
12461083 | J:118010
First Author: Bosma GC
Year: 2002
Journal: J Exp Med
Title: DNA-dependent protein kinase activity is not required for immunoglobulin class switching.
Volume: 196
Issue: 11
Pages: 1483-95
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Publication
18424731 | J:160356
First Author: Kiefer K
Year: 2008
Journal: J Immunol
Title: Antigen receptor editing in anti-DNA transitional B cells deficient for surface IgM.
Volume: 180
Issue: 9
Pages: 6094-106
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Publication
18538732 | J:166360
First Author: Wei J
Year: 2008
Journal: Cancer Cell
Title: Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.
Volume: 13
Issue: 6
Pages: 483-95
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Publication
16885376 | J:112102
First Author: Ambrosino E
Year: 2006
Journal: Cancer Res
Title: Immunosurveillance of Erbb2 carcinogenesis in transgenic mice is concealed by a dominant regulatory T-cell self-tolerance.
Volume: 66
Issue: 15
Pages: 7734-40
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Publication
8281031 | J:113713
First Author: Mamalaki C
Year: 1993
Journal: Dev Immunol
Title: Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen.
Volume: 3
Issue: 3
Pages: 159-74
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Publication
17307871 | J:125908
First Author: Luo X
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells.
Volume: 104
Issue: 8
Pages: 2821-6
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Publication
17148676 | J:116218
First Author: Calderon B
Year: 2006
Journal: Am J Pathol
Title: In CD4+ T-cell-induced diabetes, macrophages are the final effector cells that mediate islet beta-cell killing: studies from an acute model.
Volume: 169
Issue: 6
Pages: 2137-47
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Publication
11714766 | J:119045
First Author: Phillips JM
Year: 2001
Journal: J Immunol
Title: Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes.
Volume: 167
Issue: 11
Pages: 6087-91
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Publication
23426180 | J:196392
First Author: Santidrian AF
Year: 2013
Journal: J Clin Invest
Title: Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression.
Volume: 123
Issue: 3
Pages: 1068-81
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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