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Search results 1 to 100 out of 1667 for Prkdc

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Hits by Strain

Type Details Score
Gene
5591 | PRKDC
Type: gene
Organism: human
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Gene
100488663 | prkdc
Type: gene
Organism: frog, western clawed
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Gene
key_31098 | PRKDC
Type: gene
Organism: hamster, Chinese
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Gene
key_79388 | PRKDC
Type: gene
Organism: horse
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Gene
360748 | Prkdc
Type: gene
Organism: rat
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Gene
474176 | PRKDC
Type: gene
Organism: dog, domestic
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Gene
464165 | PRKDC
Type: gene
Organism: chimpanzee
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Gene
512740 | PRKDC
Type: gene
Organism: cattle
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Gene
395376 | PRKDC
Type: gene
Organism: chicken
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Gene
562283 | prkdc
Type: gene
Organism: zebrafish
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Gene
708029 | PRKDC
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:104779 | Prkdc
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
21265624 | J:261990
First Author: Fabre KM
Year: 2011
Journal: Radiat Res
Title: Murine Prkdc polymorphisms impact DNA-PKcs function.
Volume: 175
Issue: 4
Pages: 493-500
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Publication
- | J:266856
     
First Author: Peng SY
Year: 2018
Journal: MGI Direct Data Submission
Title: Direct data submission for Prkdc allele.
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Publication
40643795 | J:383195
First Author: Kim YM
Year: 2025
Journal: Transgenic Res
Title: Generation of NOD SCID mice with near-complete deletions of Il2rg and Prkdc for human cancer and HSC engraftment.
Volume: 34
Issue: 1
Pages: 35
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Publication
12857942 | J:84988
First Author: Faiola B
Year: 2003
Journal: Toxicol Sci
Title: Variations in Prkdc and susceptibility to benzene-induced toxicity in mice.
Volume: 75
Issue: 2
Pages: 321-32
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Publication
20978358 | J:166909
First Author: Papeta N
Year: 2010
Journal: J Clin Invest
Title: Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice.
Volume: 120
Issue: 11
Pages: 4055-64
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Publication
12750252 | J:83496
First Author: Blackburn AC
Year: 2003
Journal: Cancer Res
Title: BALB/c alleles for Prkdc and Cdkn2a interact to modify tumor susceptibility in Trp53+/- mice.
Volume: 63
Issue: 10
Pages: 2364-8
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Publication
31950264 | J:310493
First Author: Oliveira CF
Year: 2020
Journal: Cell Tissue Res
Title: Foxn1 and Prkdc genes are important for testis function: evidence from nude and scid adult mice.
Volume: 380
Issue: 3
Pages: 615-625
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Publication
33839407 | J:305297
 
First Author: Watanabe M
Year: 2021
Journal: Biochem Biophys Res Commun
Title: A single amino acid substitution in PRKDC is a determinant of sensitivity to Adriamycin-induced renal injury in mouse.
Volume: 556
Pages: 121-126
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Publication
11439324 | J:70283
First Author: Mori N
Year: 2001
Journal: Oncogene
Title: Variations in Prkdc encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) and susceptibility to radiation-induced apoptosis and lymphomagenesis.
Volume: 20
Issue: 28
Pages: 3609-19
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Publication
28686579 | J:269296
First Author: Gurley KE
Year: 2017
Journal: Cell Death Differ
Title: Synergy between Prkdc and Trp53 regulates stem cell proliferation and GI-ARS after irradiation.
Volume: 24
Issue: 11
Pages: 1853-1860
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Publication
26000857 | J:224779
First Author: Rahman SH
Year: 2015
Journal: PLoS Genet
Title: Rescue of DNA-PK Signaling and T-Cell Differentiation by Targeted Genome Editing in a prkdc Deficient iPSC Disease Model.
Volume: 11
Issue: 5
Pages: e1005239
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Publication
11280730 | J:68487
First Author: Yu Y
Year: 2001
Journal: Cancer Res
Title: Elevated breast cancer risk in irradiated BALB/c mice associates with unique functional polymorphism of the Prkdc (DNA-dependent protein kinase catalytic subunit) gene.
Volume: 61
Issue: 5
Pages: 1820-4
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Allele
Prkdc<em5Lutzy> | MGI:6763019
Name: protein kinase, DNA activated, catalytic polypeptide; endonuclease-mediated mutation 5, Cathy Lutz
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
9398856 | J:44390
First Author: Jhappan C
Year: 1997
Journal: Nat Genet
Title: DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus.
Volume: 17
Issue: 4
Pages: 483-6
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Publication
- | J:178522
     
First Author: Beutler B
Year: 2001
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/12/20
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Publication
10570295 | J:58652
First Author: Wang C
Year: 1999
Journal: J Immunol
Title: Irradiation-induced rescue of thymocyte differentiation and V(D)J recombination in mice lacking the catalytic subunit of DNA-dependent protein kinase.
Volume: 163
Issue: 11
Pages: 6065-71
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Publication
10805749 | J:108405
First Author: Jhappan C
Year: 2000
Journal: Mol Cell Biol
Title: The p53 response to DNA damage in vivo is independent of DNA-dependent protein kinase.
Volume: 20
Issue: 11
Pages: 4075-83
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Publication
9861008 | J:108650
First Author: Bogue MA
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation.
Volume: 95
Issue: 26
Pages: 15559-64
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Publication
- | J:224665
     
First Author: Choi JH
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for screamer2
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Publication
24253447 | J:207844
First Author: Sung YH
Year: 2014
Journal: Genome Res
Title: Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
Volume: 24
Issue: 1
Pages: 125-31
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Publication
33273464 | J:299391
First Author: Sun X
Year: 2020
Journal: Nat Commun
Title: DNA-PK deficiency potentiates cGAS-mediated antiviral innate immunity.
Volume: 11
Issue: 1
Pages: 6182
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Publication
38286241 | J:359504
 
First Author: Oh T
Year: 2024
Journal: Radiother Oncol
Title: DNA-dependent protein kinase regulates cytosolic double-stranded DNA secretion from irradiated macrophages to increase radiosensitivity of tumors.
Volume: 193
Pages: 110111
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Publication
37651888 | J:341230
 
First Author: Takagi Y
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Characterization of novel, severely immunodeficient Prkdc(?ex57/?ex57) mice.
Volume: 678
Pages: 193-199
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Publication
- | J:239221
     
First Author: Charles River
Year: 2017
Journal: Scientific info. sheet (http://www.criver.com/files/pdfs/rms/ncg/ncg-mouse-scientific--sheet.aspx)
Title: NOD CRISPR Prkdcil2r Gamma (NCG) Triple-Immunodeficient Mouse Model
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Publication
19664609 | J:157421
 
First Author: Liu J
Year: 2009
Journal: Brain Res
Title: The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation.
Volume: 1296
Pages: 164-75
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Publication
25448685 | J:217529
First Author: Ganesan S
Year: 2014
Journal: Toxicol Appl Pharmacol
Title: Enhanced susceptibility of ovaries from obese mice to 7,12-dimethylbenz[a]anthracene-induced DNA damage.
Volume: 281
Issue: 2
Pages: 203-10
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Publication
16687486 | J:108789
First Author: Gladdy RA
Year: 2006
Journal: Mol Cancer Res
Title: p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc.
Volume: 4
Issue: 5
Pages: 311-8
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Publication
10337614 | J:54501
First Author: Lund J
Year: 1999
Journal: Mamm Genome
Title: Sequence-ready physical map of the mouse chromosome 16 region with conserved synteny to the human velocardiofacial syndrome region on 22q11.2.
Volume: 10
Issue: 5
Pages: 438-43
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Allele
Prkdc<em1Lutzy> | MGI:6877105
Name: protein kinase, DNA activated, catalytic polypeptide; endonuclease-mediated mutation 1, Cathy Lutz
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready
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Protein Coding Gene
MGP_CAROLIEiJ_G0020487 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0022552 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0022513 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0022490 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0022518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022285 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_104779 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022254 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022385 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022361 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0022453 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022383 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0022980 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0021554 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021860 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016192 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021382 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9122213 | J:39329
First Author: Araki R
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice.
Volume: 94
Issue: 6
Pages: 2438-43
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Publication
9339376 | J:43493
First Author: Fujimori A
Year: 1997
Journal: Genomics
Title: The murine DNA-PKcs gene consists of 86 exons dispersed in more than 250 kb.
Volume: 45
Issue: 1
Pages: 194-9
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Publication
8881030 | J:37619
First Author: Hamatani K
Year: 1996
Journal: Immunogenetics
Title: Cloning and chromosomal mapping of the mouse DNA-dependent protein kinase gene.
Volume: 45
Issue: 1
Pages: 1-5
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Publication
8816792 | J:35393
First Author: Blunt T
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse.
Volume: 93
Issue: 19
Pages: 10285-90
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Publication
8816463 | J:35350
First Author: Danska JS
Year: 1996
Journal: Mol Cell Biol
Title: Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes.
Volume: 16
Issue: 10
Pages: 5507-17
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Publication
12426399 | J:111398
First Author: Espejel S
Year: 2002
Journal: EMBO J
Title: Functional interaction between DNA-PKcs and telomerase in telomere length maintenance.
Volume: 21
Issue: 22
Pages: 6275-87
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Publication
15699352 | J:96632
First Author: Zheng Z
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse.
Volume: 102
Issue: 7
Pages: 2502-7
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Publication
4107291 | J:5237
First Author: Graff RJ
Year: 1970
Journal: Transplant Proc
Title: Polymorphism of histocompatibility genes in the mouse.
Volume: 2
Issue: 1
Pages: 15-23
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Publication
8094405 | J:111476
First Author: Shores EW
Year: 1993
Journal: J Immunol
Title: Structurally distinct T cell receptor complexes on developmentally distinct T cell populations in severe combined immunodeficiency mice expressing a TCR beta transgene.
Volume: 150
Issue: 4
Pages: 1263-75
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Publication
19948826 | J:156380
First Author: Ebrahem Q
Year: 2010
Journal: Am J Pathol
Title: Cross-talk between vascular endothelial growth factor and matrix metalloproteinases in the induction of neovascularization in vivo.
Volume: 176
Issue: 1
Pages: 496-503
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Publication
20485377 | J:162490
First Author: Mizrahi K
Year: 2010
Journal: Leukemia
Title: Regulatory functions of TRAIL in hematopoietic progenitors: human umbilical cord blood and murine bone marrow transplantation.
Volume: 24
Issue: 7
Pages: 1325-34
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Publication
27768891 | J:357922
First Author: Gilchuk I
Year: 2016
Journal: Cell
Title: Cross-Neutralizing and Protective Human Antibody Specificities to Poxvirus Infections.
Volume: 167
Issue: 3
Pages: 684-694.e9
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Publication
22403295 | J:196728
First Author: Yi S
Year: 2012
Journal: Diabetes
Title: Adoptive transfer with in vitro expanded human regulatory T cells protects against porcine islet xenograft rejection via interleukin-10 in humanized mice.
Volume: 61
Issue: 5
Pages: 1180-91
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Publication
16297152 | J:107603
First Author: Katakura T
Year: 2005
Journal: Clin Exp Immunol
Title: Immunological control of methicillin-resistant Staphylococcus aureus (MRSA) infection in an immunodeficient murine model of thermal injuries.
Volume: 142
Issue: 3
Pages: 419-25
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Publication
8281031 | J:113713
First Author: Mamalaki C
Year: 1993
Journal: Dev Immunol
Title: Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen.
Volume: 3
Issue: 3
Pages: 159-74
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Publication
11869679 | J:132052
First Author: Hugues S
Year: 2002
Journal: Immunity
Title: Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells.
Volume: 16
Issue: 2
Pages: 169-81
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Publication
40113953 | J:376637
First Author: Coughlin GM
Year: 2026
Journal: Nat Biotechnol
Title: Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo.
Volume: 44
Issue: 1
Pages: 133-145
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Publication
23825700 | J:204342
First Author: Rauner G
Year: 2013
Journal: PLoS One
Title: Development of Foreign Mammary Epithelial Morphology in the Stroma of Immunodeficient Mice.
Volume: 8
Issue: 6
Pages: e68637
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Publication
7981149 | J:22574
First Author: Maeda K
Year: 1994
Journal: Int Immunol
Title: Split tolerance between spleen and lymph node cells in severe combined immunodeficiency mice grafted with AKR fetal liver cells.
Volume: 6
Issue: 8
Pages: 1213-9
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Publication
8633371 | J:33268
First Author: MacKenzie DA
Year: 1996
Journal: Transplantation
Title: Acute graft rejection of human fetal pancreas allografts using donor-specific human peripheral blood lymphocytes in the SCID mouse.
Volume: 61
Issue: 10
Pages: 1461-4
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Publication
9311846 | J:42952
First Author: Pewe L
Year: 1997
Journal: J Virol
Title: Cytotoxic T-cell-resistant variants arise at early times after infection in C57BL/6 but not in SCID mice infected with a neurotropic coronavirus.
Volume: 71
Issue: 10
Pages: 7640-7
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Publication
15047613 | J:89082
First Author: Pauza ME
Year: 2004
Journal: Diabetes
Title: T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes.
Volume: 53
Issue: 4
Pages: 978-88
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Publication
26851521 | J:287471
 
First Author: Quadros RM
Year: 2016
Journal: J Immunol Methods
Title: Simple and reliable genotyping protocol for mouse Prkdc(SCID) mutation.
Volume: 431
Pages: 60-2
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Publication
20124219 | J:162610
First Author: Banerjee P
Year: 2010
Journal: Blood
Title: Adult T-cell leukemia/lymphoma development in HTLV-1-infected humanized SCID mice.
Volume: 115
Issue: 13
Pages: 2640-8
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Publication
16895987 | J:111775
First Author: Chaparro RJ
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes.
Volume: 103
Issue: 33
Pages: 12475-80
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Publication
23747725 | J:204420
First Author: Matsuoka K
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Generation of mouse models for type 1 diabetes by selective depletion of pancreatic beta cells using toxin receptor-mediated cell knockout.
Volume: 436
Issue: 3
Pages: 400-5
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Publication
17336387 | J:119811
First Author: S?v?re S
Year: 2007
Journal: Mol Immunol
Title: CD8+ T lymphocytes specific for glutamic acid decarboxylase 90-98 epitope mediate diabetes in NOD SCID mouse.
Volume: 44
Issue: 11
Pages: 2950-60
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Publication
26961115 | J:274578
First Author: Leeth CM
Year: 2016
Journal: Diabetes
Title: B-lymphocytes expressing an Ig specificity recognizing the pancreatic ?-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice.
Volume: 65
Issue: 7
Pages: 1977-1987
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Publication
21169553 | J:168755
First Author: Yang GX
Year: 2011
Journal: J Immunol
Title: CD8 T cells mediate direct biliary ductule damage in nonobese diabetic autoimmune biliary disease.
Volume: 186
Issue: 2
Pages: 1259-67
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Publication
15531925 | J:239806
First Author: Zhang YW
Year: 2005
Journal: Oncogene
Title: Enhanced growth of human met-expressing xenografts in a new strain of immunocompromised mice transgenic for human hepatocyte growth factor/scatter factor.
Volume: 24
Issue: 1
Pages: 101-6
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Publication
14635033 | J:87142
First Author: Jaakkola I
Year: 2003
Journal: Eur J Immunol
Title: Diabetogenic T cells are primed both in pancreatic and gut-associated lymph nodes in NOD mice.
Volume: 33
Issue: 12
Pages: 3255-64
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Publication
31509739 | J:286169
First Author: Jones RE
Year: 2019
Journal: Cell Rep
Title: Skeletal Stem Cell-Schwann Cell Circuitry in Mandibular Repair.
Volume: 28
Issue: 11
Pages: 2757-2766.e5
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Publication
10910267 | J:93486
First Author: Chen AM
Year: 2000
Journal: Transplantation
Title: Porcine stem cell engraftment and seeding of murine thymus with class II+ cells in mice expressing porcine cytokines: toward tolerance induction across discordant xenogeneic barriers.
Volume: 69
Issue: 12
Pages: 2484-90
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Publication
20147609 | J:158609
First Author: Crowley SD
Year: 2010
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Lymphocyte responses exacerbate angiotensin II-dependent hypertension.
Volume: 298
Issue: 4
Pages: R1089-97
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Publication
3519770 | J:8299
First Author: Fulop GM
Year: 1986
Journal: J Immunol
Title: Full reconstitution of the immune deficiency in scid mice with normal stem cells requires low-dose irradiation of the recipients.
Volume: 136
Issue: 12
Pages: 4438-43
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Publication
28238547 | J:256055
First Author: Espuny-Camacho I
Year: 2017
Journal: Neuron
Title: Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Volume: 93
Issue: 5
Pages: 1066-1081.e8
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Publication
35924921 | J:331764
First Author: Abdelnabi R
Year: 2022
Journal: J Virol
Title: A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection.
Volume: 96
Issue: 16
Pages: e0075822
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Publication
7983730 | J:21933
First Author: Haller BL
Year: 1995
Journal: J Virol
Title: Genetic mapping of reovirus virulence and organ tropism in severe combined immunodeficient mice: organ-specific virulence genes.
Volume: 69
Issue: 1
Pages: 357-64
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Publication
19808649 | J:154703
First Author: Song X
Year: 2009
Journal: Am J Pathol
Title: A mouse model of inducible liver injury caused by tet-on regulated urokinase for studies of hepatocyte transplantation.
Volume: 175
Issue: 5
Pages: 1975-83
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Publication
19421183 | J:193381
First Author: Bonifazi P
Year: 2009
Journal: Mucosal Immunol
Title: Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans.
Volume: 2
Issue: 4
Pages: 362-74
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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