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Search results 1 to 100 out of 527 for Prkn

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0.046s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication  
First Author: Edmunds LR
Year: 2020
Journal: Mol Metab
Title: Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance.
Volume: 41
Pages: 101051
Publication
First Author: Lockhart PJ
Year: 2004
Journal: Mov Disord
Title: It's a double knock-out! The quaking mouse is a spontaneous deletion of parkin and parkin co-regulated gene (PACRG).
Volume: 19
Issue: 1
Pages: 101-4
Publication  
First Author: Aksoy Yasar FB
Year: 2022
Journal: Front Cell Dev Biol
Title: Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma.
Volume: 10
Pages: 931387
Publication
First Author: Matheoud D
Year: 2019
Journal: Nature
Title: Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice.
Volume: 571
Issue: 7766
Pages: 565-569
Publication  
First Author: Li J
Year: 2022
Journal: Front Cell Dev Biol
Title: Reciprocal Regulation of Mitofusin 2-Mediated Mitophagy and Mitochondrial Fusion by Different PINK1 Phosphorylation Events.
Volume: 10
Pages: 868465
Publication
First Author: El Kodsi DN
Year: 2023
Journal: Acta Neuropathol Commun
Title: Parkin coregulates glutathione metabolism in adult mammalian brain.
Volume: 11
Issue: 1
Pages: 19
Publication  
First Author: Bhatia D
Year: 2019
Journal: JCI Insight
Title: Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis.
Volume: 4
Issue: 23
Publication
First Author: Sliter DA
Year: 2018
Journal: Nature
Title: Parkin and PINK1 mitigate STING-induced inflammation.
Volume: 561
Issue: 7722
Pages: 258-262
Publication
First Author: Araya J
Year: 2019
Journal: Autophagy
Title: PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis.
Volume: 15
Issue: 3
Pages: 510-526
Publication
First Author: Choong CJ
Year: 2021
Journal: Autophagy
Title: Alternative mitochondrial quality control mediated by extracellular release.
Volume: 17
Issue: 10
Pages: 2962-2974
Publication
First Author: Yamada T
Year: 2019
Journal: Autophagy
Title: SQSTM1/p62 promotes mitochondrial ubiquitination independently of PINK1 and PRKN/parkin in mitophagy.
Volume: 15
Issue: 11
Pages: 2012-2018
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ko HS
Year: 2005
Journal: J Neurosci
Title: Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.
Volume: 25
Issue: 35
Pages: 7968-78
Publication  
First Author: Yun J
Year: 2014
Journal: Elife
Title: MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin.
Volume: 3
Pages: e01958
Publication
First Author: Kuroda Y
Year: 2012
Journal: Hum Mol Genet
Title: Parkin interacts with Klokin1 for mitochondrial import and maintenance of membrane potential.
Volume: 21
Issue: 5
Pages: 991-1003
Publication
First Author: Kitada T
Year: 2000
Journal: Mamm Genome
Title: Molecular cloning, gene expression, and identification of a splicing variant of the mouse parkin gene.
Volume: 11
Issue: 6
Pages: 417-21
Publication
First Author: Huynh DP
Year: 2001
Journal: Brain Res Dev Brain Res
Title: Differential expression and tissue distribution of parkin isoforms during mouse development.
Volume: 130
Issue: 2
Pages: 173-81
Publication
First Author: Moore TM
Year: 2022
Journal: Nat Commun
Title: Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes.
Volume: 13
Issue: 1
Pages: 6661
Publication
First Author: Stevens DA
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration.
Volume: 112
Issue: 37
Pages: 11696-701
Publication
First Author: Ramsey CP
Year: 2010
Journal: J Neurochem
Title: Identification and characterization of a novel endogenous murine parkin mutation.
Volume: 113
Issue: 2
Pages: 402-17
Publication  
First Author: McWilliams TG
Year: 2018
Journal: Open Biol
Title: Phosphorylation of Parkin at serine 65 is essential for its activation in vivo.
Volume: 8
Issue: 11
Publication
First Author: Itier JM
Year: 2003
Journal: Hum Mol Genet
Title: Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse.
Volume: 12
Issue: 18
Pages: 2277-91
Publication
First Author: Perucho J
Year: 2010
Journal: Exp Neurol
Title: The effects of parkin suppression on the behaviour, amyloid processing, and cell survival in APP mutant transgenic mice.
Volume: 221
Issue: 1
Pages: 54-67
Publication  
First Author: Fournier M
Year: 2013
Journal: BMC Neurosci
Title: Parkin depletion delays motor decline dose-dependently without overtly affecting neuropathology in α-synuclein transgenic mice.
Volume: 14
Pages: 135
Publication
First Author: Periquet M
Year: 2005
Journal: J Neurochem
Title: Proteomic analysis of parkin knockout mice: alterations in energy metabolism, protein handling and synaptic function.
Volume: 95
Issue: 5
Pages: 1259-76
Publication
First Author: Rodríguez-Navarro JA
Year: 2008
Journal: Hum Mol Genet
Title: Parkin deletion causes cerebral and systemic amyloidosis in human mutated tau over-expressing mice.
Volume: 17
Issue: 20
Pages: 3128-43
Publication  
First Author: Key J
Year: 2019
Journal: Neurobiol Dis
Title: Ubiquitylome profiling of Parkin-null brain reveals dysregulation of calcium homeostasis factors ATP1A2, Hippocalcin and GNA11, reflected by altered firing of noradrenergic neurons.
Volume: 127
Pages: 114-130
Publication
First Author: Menéndez J
Year: 2006
Journal: Hum Mol Genet
Title: Suppression of Parkin enhances nigrostriatal and motor neuron lesion in mice over-expressing human-mutated tau protein.
Volume: 15
Issue: 13
Pages: 2045-58
Publication
First Author: Rodríguez-Navarro JA
Year: 2007
Journal: J Neurochem
Title: Mortality, oxidative stress and tau accumulation during ageing in parkin null mice.
Volume: 103
Issue: 1
Pages: 98-114
Publication
First Author: Rodríguez-Navarro JA
Year: 2010
Journal: Neurobiol Dis
Title: Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation.
Volume: 39
Issue: 3
Pages: 423-38
Publication
First Author: González S
Year: 2005
Journal: Brain Res
Title: Cannabinoid CB(1) receptors in the basal ganglia and motor response to activation or blockade of these receptors in parkin-null mice.
Volume: 1046
Issue: 1-2
Pages: 195-206
Publication
First Author: Gouspillou G
Year: 2018
Journal: J Physiol
Title: Protective role of Parkin in skeletal muscle contractile and mitochondrial function.
Volume: 596
Issue: 13
Pages: 2565-2579
Publication  
First Author: Rubio I
Year: 2009
Journal: Brain Res
Title: Effects of partial suppression of parkin on huntingtin mutant R6/1 mice.
Volume: 1281
Pages: 91-100
Publication  
First Author: Gaudioso A
Year: 2019
Journal: Front Neurosci
Title: Lipidomic Alterations in the Mitochondria of Aged Parkin Null Mice Relevant to Autophagy.
Volume: 13
Pages: 329
Publication
First Author: Mena MA
Year: 2009
Journal: FEBS Lett
Title: NP7 protects from cell death induced by oxidative stress in neuronal and glial midbrain cultures from parkin null mice.
Volume: 583
Issue: 1
Pages: 168-74
Publication
First Author: Rial D
Year: 2014
Journal: PLoS One
Title: Behavioral phenotyping of Parkin-deficient mice: looking for early preclinical features of Parkinson's disease.
Volume: 9
Issue: 12
Pages: e114216
Publication
First Author: Guerrero R
Year: 2009
Journal: Acta Neuropathol
Title: Hyperphosphorylated tau aggregates in the cortex and hippocampus of transgenic mice with mutant human FTDP-17 Tau and lacking the PARK2 gene.
Volume: 117
Issue: 2
Pages: 159-68
Publication  
First Author: Tourville A
Year: 2022
Journal: Cells
Title: Modelling α-Synuclein Aggregation and Neurodegeneration with Fibril Seeds in Primary Cultures of Mouse Dopaminergic Neurons.
Volume: 11
Issue: 10
Publication
First Author: Damiano M
Year: 2014
Journal: PLoS One
Title: Tissue- and cell-specific mitochondrial defect in Parkin-deficient mice.
Volume: 9
Issue: 6
Pages: e99898
Publication
First Author: Zhu XR
Year: 2007
Journal: Eur J Neurosci
Title: Non-motor behavioural impairments in parkin-deficient mice.
Volume: 26
Issue: 7
Pages: 1902-11
Publication
First Author: Stichel CC
Year: 2007
Journal: Hum Mol Genet
Title: Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage.
Volume: 16
Issue: 20
Pages: 2377-93
Publication
First Author: Um JW
Year: 2010
Journal: J Neurosci
Title: Parkin directly modulates 26S proteasome activity.
Volume: 30
Issue: 35
Pages: 11805-14
Publication
First Author: Schmidt S
Year: 2011
Journal: Hum Mol Genet
Title: Genetic mouse models for Parkinson's disease display severe pathology in glial cell mitochondria.
Volume: 20
Issue: 6
Pages: 1197-211
Publication
First Author: Roth JA
Year: 2010
Journal: J Neurochem
Title: Parkin regulates metal transport via proteasomal degradation of the 1B isoforms of divalent metal transporter 1.
Volume: 113
Issue: 2
Pages: 454-64
Publication
First Author: Von Coelln R
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Loss of locus coeruleus neurons and reduced startle in parkin null mice.
Volume: 101
Issue: 29
Pages: 10744-9
Publication
First Author: Thomas B
Year: 2007
Journal: Neurobiol Dis
Title: MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity.
Volume: 26
Issue: 2
Pages: 312-22
Publication
First Author: Kao SY
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Regulation of DNA repair by parkin.
Volume: 382
Issue: 2
Pages: 321-5
Publication
First Author: Han K
Year: 2017
Journal: Sci Rep
Title: Parkin regulation of CHOP modulates susceptibility to cardiac endoplasmic reticulum stress.
Volume: 7
Issue: 1
Pages: 2093
Publication  
First Author: Esteca MV
Year: 2020
Journal: Int J Mol Sci
Title: Loss of Parkin Results in Altered Muscle Stem Cell Differentiation during Regeneration.
Volume: 21
Issue: 21
Publication
First Author: Stauch KL
Year: 2023
Journal: Sci Rep
Title: Longitudinal in vivo metabolic labeling reveals tissue-specific mitochondrial proteome turnover rates and proteins selectively altered by parkin deficiency.
Volume: 13
Issue: 1
Pages: 11414
Publication  
First Author: Palomo GM
Year: 2018
Journal: EMBO Mol Med
Title: Parkin is a disease modifier in the mutant SOD1 mouse model of ALS.
Volume: 10
Issue: 10
Publication
First Author: Kubli DA
Year: 2013
Journal: J Biol Chem
Title: Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction.
Volume: 288
Issue: 2
Pages: 915-26
Publication
First Author: Chen CCW
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: Parkin is required for exercise-induced mitophagy in muscle: impact of aging.
Volume: 315
Issue: 3
Pages: E404-E415
Publication
First Author: Peker N
Year: 2018
Journal: Am J Physiol Cell Physiol
Title: Loss of Parkin impairs mitochondrial function and leads to muscle atrophy.
Volume: 315
Issue: 2
Pages: C164-C185
Publication
First Author: Lee SB
Year: 2015
Journal: Mol Cell
Title: Parkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1.
Volume: 60
Issue: 1
Pages: 21-34
Publication
First Author: Shires SE
Year: 2020
Journal: Sci Rep
Title: Nuclear Parkin Activates the ERRα Transcriptional Program and Drives Widespread Changes in Gene Expression Following Hypoxia.
Volume: 10
Issue: 1
Pages: 8499
Publication
First Author: Wu NN
Year: 2023
Journal: Exp Mol Med
Title: Site-specific ubiquitination of VDAC1 restricts its oligomerization and mitochondrial DNA release in liver fibrosis.
Volume: 55
Issue: 1
Pages: 269-280
Publication
First Author: Lonskaya I
Year: 2014
Journal: J Mol Med (Berl)
Title: Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance.
Volume: 92
Issue: 4
Pages: 373-86
Publication
First Author: Kitada T
Year: 2009
Journal: J Neurochem
Title: Impaired dopamine release and synaptic plasticity in the striatum of parkin-/- mice.
Volume: 110
Issue: 2
Pages: 613-21
Publication
First Author: Zhang C
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect.
Volume: 108
Issue: 39
Pages: 16259-64
Publication
First Author: Bone NB
Year: 2021
Journal: Sci Rep
Title: AMPK activates Parkin independent autophagy and improves post sepsis immune defense against secondary bacterial lung infections.
Volume: 11
Issue: 1
Pages: 12387
Publication
First Author: Costa DK
Year: 2016
Journal: Am J Physiol Endocrinol Metab
Title: Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice.
Volume: 311
Issue: 1
Pages: E105-16
Publication
First Author: Williams JA
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice.
Volume: 309
Issue: 5
Pages: G324-40
Publication
First Author: Lee SB
Year: 2019
Journal: Nat Cell Biol
Title: The AMPK-Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome.
Volume: 21
Issue: 8
Pages: 940-951
Publication  
First Author: Pickrell AM
Year: 2013
Journal: Mol Cell Neurosci
Title: Mouse models of Parkinson's disease associated with mitochondrial dysfunction.
Volume: 55
Pages: 87-94
Publication
First Author: Singh K
Year: 2018
Journal: Glia
Title: Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation.
Volume: 66
Issue: 11
Pages: 2427-2437
Publication  
First Author: Cartelli D
Year: 2018
Journal: Neurobiol Aging
Title: Parkin absence accelerates microtubule aging in dopaminergic neurons.
Volume: 61
Pages: 66-74
Publication
First Author: Xin D
Year: 2018
Journal: J Biol Chem
Title: Parkin negatively regulates the antiviral signaling pathway by targeting TRAF3 for degradation.
Volume: 293
Issue: 31
Pages: 11996-12010
Publication
First Author: Liu X
Year: 2019
Journal: Hum Mol Genet
Title: Ubiquitin specific protease-13 independently regulates parkin ubiquitination and alpha-synuclein clearance in alpha-synucleinopathies.
Volume: 28
Issue: 4
Pages: 548-560
Publication
First Author: Peng H
Year: 2020
Journal: Acta Biochim Biophys Sin (Shanghai)
Title: Parkin deficiency accentuates chronic alcohol intake-induced tissue injury and autophagy defects in brain, liver and skeletal muscle.
Volume: 52
Issue: 6
Pages: 665-674
Publication  
First Author: Cairó M
Year: 2019
Journal: EMBO Rep
Title: Parkin controls brown adipose tissue plasticity in response to adaptive thermogenesis.
Volume: 20
Issue: 5
Publication  
First Author: Song L
Year: 2017
Journal: Neurobiol Dis
Title: Parkin deficiency accelerates consequences of mitochondrial DNA deletions and Parkinsonism.
Volume: 100
Pages: 30-38
Publication
First Author: Wenqiang C
Year: 2014
Journal: Hum Mol Genet
Title: Parkin-mediated reduction of nuclear and soluble TDP-43 reverses behavioral decline in symptomatic mice.
Volume: 23
Issue: 18
Pages: 4960-9
Publication  
First Author: Mooli RGR
Year: 2020
Journal: Metabolism
Title: Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.
Volume: 107
Pages: 154225