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Search results 1 to 100 out of 135 for Prm2

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Hits by Category

Hits by Strain

Type Details Score
Gene
5620 | PRM2
Type: gene
Organism: human
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Gene
key_33444 | PRM2
Type: gene
Organism: pig, domestic
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Gene
25345 | Prm2
Type: gene
Organism: rat
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Gene
453921 | PRM2
Type: gene
Organism: chimpanzee
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Gene
100686082 | PRM2
Type: gene
Organism: dog, domestic
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Gene
281424 | PRM2
Type: gene
Organism: cattle
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Gene
711424 | PRM2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:97766 | Prm2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR000492 | PRM2
Type: Family
Description: The protamines are a diverse family of small arginine-rich proteins that are synthesized in the late-stage spermatids of many animals and plants. They bind to DNA, condensing the spermatid genome into a genetically inactive state. The two protamines found in mammals, P1 and P2, are the most widely studied. Both P1 and P2 have been shown to be required for normal sperm function in primates and many rodents []. This entry represents protamine 2 (PRM2), which is present in haploid spermatogenic cells of human, mouse and other primates. The protamine P2 gene codes for a P2 precursor, pro-P2 which is later processed by proteolytic cleavages in its N-terminal region to form the mature P2 protamines [].
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Publication
12620939 | J:89324
First Author: Cho C
Year: 2003
Journal: Biol Reprod
Title: Protamine 2 deficiency leads to sperm DNA damage and embryo death in mice.
Volume: 69
Issue: 1
Pages: 211-7
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Publication
11326282 | J:69127
First Author: Cho C
Year: 2001
Journal: Nat Genet
Title: Haploinsufficiency of protamine-1 or -2 causes infertility in mice.
Volume: 28
Issue: 1
Pages: 82-6
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Publication
28743739 | J:248360
First Author: Malla AB
Year: 2017
Journal: J Cell Sci
Title: IP6K1 is essential for chromatoid body formation and temporal regulation of Tnp2 and Prm2 expression in mouse spermatids.
Volume: 130
Issue: 17
Pages: 2854-2866
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Protein
P07978
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: false
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Protein
C3U1S0
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: false
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Protein
C3U1R8
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: false
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Protein
Q545M0
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: false
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Protein
C3U1R7
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: false
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Protein
C3U1R6
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: false
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Publication
17903313 | -
First Author: Balhorn R
Year: 2007
Journal: Genome Biol
Title: The protamine family of sperm nuclear proteins.
Volume: 8
Issue: 9
Pages: 227
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Publication
8513810 | -
First Author: Retief JD
Year: 1993
Journal: Eur J Biochem
Title: Evolution of pro-protamine P2 genes in primates.
Volume: 214
Issue: 2
Pages: 609-15
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Publication
27833122 | J:243626
 
First Author: Schneider S
Year: 2016
Journal: Sci Rep
Title: Re-visiting the Protamine-2 locus: deletion, but not haploinsufficiency, renders male mice infertile.
Volume: 6
Pages: 36764
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Publication
32727081 | J:295027
 
First Author: Schneider S
Year: 2020
Journal: Cells
Title: Protamine-2 Deficiency Initiates a Reactive Oxygen Species (ROS)-Mediated Destruction Cascade during Epididymal Sperm Maturation in Mice.
Volume: 9
Issue: 8
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Publication
35763544 | J:360850
First Author: Arévalo L
Year: 2022
Journal: PLoS Genet
Title: Loss of the cleaved-protamine 2 domain leads to incomplete histone-to-protamine exchange and infertility in mice.
Volume: 18
Issue: 6
Pages: e1010272
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Publication
24146628 | J:203763
First Author: Fukuda N
Year: 2013
Journal: PLoS Genet
Title: The transacting factor CBF-A/Hnrnpab binds to the A2RE/RTS element of protamine 2 mRNA and contributes to its translational regulation during mouse spermatogenesis.
Volume: 9
Issue: 10
Pages: e1003858
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Publication
30914484 | J:278367
 
First Author: Itoh K
Year: 2019
Journal: Sci Signal
Title: Dephosphorylation of protamine 2 at serine 56 is crucial for murine sperm maturation in vivo.
Volume: 12
Issue: 574
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Publication
22086916 | J:178957
First Author: Dai L
Year: 2011
Journal: J Biol Chem
Title: Testis-specific miRNA-469 up-regulated in gonadotropin-regulated testicular RNA helicase (GRTH/DDX25)-null mice silences transition protein 2 and protamine 2 messages at sites within coding region: implications of its role in germ cell development.
Volume: 286
Issue: 52
Pages: 44306-18
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Publication
10369260 | J:55515
First Author: Zhong J
Year: 1999
Journal: Nat Genet
Title: A double-stranded RNA binding protein required for activation of repressed messages in mammalian germ cells.
Volume: 22
Issue: 2
Pages: 171-4
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Publication
15452126 | J:95175
First Author: Martins RP
Year: 2004
Journal: J Biol Chem
Title: Nuclear matrix interactions at the human protamine domain: a working model of potentiation.
Volume: 279
Issue: 50
Pages: 51862-8
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Publication
8720108 | J:30554
First Author: Schlüter G
Year: 1996
Journal: Mol Reprod Dev
Title: Sequence analysis of the conserved protamine gene cluster shows that it contains a fourth expressed gene.
Volume: 43
Issue: 1
Pages: 1-6
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Protein Coding Gene
MGP_CAROLIEiJ_G0020450 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0022514 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0022476 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0022452 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0022480 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022247 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97766 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022929 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021774 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022216 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022347 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022323 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0022415 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022345 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0022942 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0021514 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021822 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016157 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021344 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
3600661 | J:8769
First Author: Yelick PC
Year: 1987
Journal: Mol Cell Biol
Title: Mouse protamine 2 is synthesized as a precursor whereas mouse protamine 1 is not.
Volume: 7
Issue: 6
Pages: 2173-9
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Publication
2015343 | J:11118
First Author: Johnson PA
Year: 1991
Journal: Biol Reprod
Title: Protein binding regions in the mouse and rat protamine-2 genes.
Volume: 44
Issue: 1
Pages: 127-34
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Publication
9015758 | J:38739
First Author: Ha H
Year: 1997
Journal: J Cell Biochem
Title: Tissue-specific protein-DNA interactions of the mouse protamine 2 gene promoter.
Volume: 64
Issue: 1
Pages: 94-105
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Publication
9341127 | J:44577
First Author: Yiu GK
Year: 1997
Journal: J Biol Chem
Title: Novel testis-specific protein-DNA interactions activate transcription of the mouse protamine 2 gene during spermatogenesis.
Volume: 272
Issue: 43
Pages: 26926-33
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GXD Expression
GXD Expression
     
Probe: MGI:3701288
Assay Type: RT-PCR
Annotation Date: 2007-03-28
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3701331
Age: postnatal
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3701288
Assay Type: RT-PCR
Annotation Date: 2007-03-28
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3701331
Age: postnatal
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3701288
Assay Type: RT-PCR
Annotation Date: 2007-03-28
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3701331
Age: postnatal
Specimen Label: -/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4356487
Assay Type: RT-PCR
Annotation Date: 2009-09-14
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4357820
Age: postnatal week 12
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4356487
Assay Type: RT-PCR
Annotation Date: 2009-09-14
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4357820
Age: postnatal week 12
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4356487
Assay Type: RT-PCR
Annotation Date: 2009-09-14
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4357820
Age: postnatal week 12
Specimen Label: -/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5637960
Assay Type: Northern blot
Annotation Date: 2015-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5637972
Age: postnatal day 45
Image: 2
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5637960
Assay Type: Northern blot
Annotation Date: 2015-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5637972
Age: postnatal day 45
Image: 2
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5637960
Assay Type: Northern blot
Annotation Date: 2015-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5637972
Age: postnatal day 45
Image: 2
Specimen Label: -/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7781439
Assay Type: RT-PCR
Annotation Date: 2024-11-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7781525
Age: postnatal
Specimen Label: 1
Detected: true
Specimen Num: 2
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Publication
3676400 | J:8916
First Author: Bower PA
Year: 1987
Journal: Biol Reprod
Title: Both P1 and P2 protamine genes are expressed in mouse, hamster, and rat.
Volume: 37
Issue: 2
Pages: 479-88
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Publication
8185929 | J:17141
First Author: Green GR
Year: 1994
Journal: Mol Reprod Dev
Title: Synthesis and processing of mammalian protamines and transition proteins.
Volume: 37
Issue: 3
Pages: 255-63
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Publication
6688229 | J:7131
First Author: Kleene KC
Year: 1983
Journal: Dev Biol
Title: cDNA clones encoding cytoplasmic poly(A)+ RNAs which first appear at detectable levels in haploid phases of spermatogenesis in the mouse.
Volume: 98
Issue: 2
Pages: 455-64
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Publication
3008352 | J:8254
First Author: Hecht NB
Year: 1986
Journal: Somat Cell Mol Genet
Title: Mapping of haploid expressed genes: genes for both mouse protamines are located on chromosome 16.
Volume: 12
Issue: 2
Pages: 203-8
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Publication
2614060 | J:10267
First Author: Reeves RH
Year: 1989
Journal: J Hered
Title: Mapping of PRM1 to human chromosome 16 and tight linkage of Prm-1 and Prm-2 on mouse chromosome 16.
Volume: 80
Issue: 6
Pages: 442-6
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Publication
7813783 | J:22581
First Author: Fajardo MA
Year: 1994
Journal: Dev Biol
Title: Germ cell-specific proteins interact with the 3' untranslated regions of Prm-1 and Prm-2 mRNA.
Volume: 166
Issue: 2
Pages: 643-53
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Publication
- | J:4261
First Author: Miller RD
Year: 1993
Journal: Mouse Genome
Title: Orientation of mahoganoid relative to Prm-2
Volume: 91
Issue: 1
Pages: 133
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Publication
3358932 | J:9141
First Author: Johnson PA
Year: 1988
Journal: Biochim Biophys Acta
Title: Sequence homologies in the mouse protamine 1 and 2 genes.
Volume: 950
Issue: 1
Pages: 45-53
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Publication
9107674 | J:39621
First Author: Choi YC
Year: 1997
Journal: Mamm Genome
Title: Genomic analysis of the mouse protamine 1, protamine 2, and transition protein 2 gene cluster reveals hypermethylation in expressing cells.
Volume: 8
Issue: 5
Pages: 317-23
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Publication
10369265 | J:55514
First Author: Delpire E
Year: 1999
Journal: Nat Genet
Title: Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter.
Volume: 22
Issue: 2
Pages: 192-5
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Publication
1627265 | J:1524
First Author: Keime S
Year: 1992
Journal: Biol Chem Hoppe Seyler
Title: Characterization of four genes encoding basic proteins of the porcine spermatid nucleus and close linkage of three of them.
Volume: 373
Issue: 5
Pages: 261-70
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Publication
1395729 | J:2900
First Author: Engel W
Year: 1992
Journal: Cytogenet Cell Genet
Title: The genes for protamine 1 and 2 (PRM1 and PRM2) and transition protein 2 (TNP2) are closely linked in the mammalian genome.
Volume: 61
Issue: 2
Pages: 158-9
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Publication
15665108 | J:96105
First Author: Yang J
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: The DNA/RNA-binding protein MSY2 marks specific transcripts for cytoplasmic storage in mouse male germ cells.
Volume: 102
Issue: 5
Pages: 1513-8
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Publication
14680821 | J:86940
First Author: Xing W
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Role of follitropin receptor signaling in nuclear protein transitions and chromatin condensation during spermatogenesis.
Volume: 312
Issue: 3
Pages: 697-701
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Publication
1797230 | J:11631
First Author: Reeves RH
Year: 1991
Journal: Mamm Genome
Title: Comparison of interspecific to intersubspecific backcrosses demonstrates species and sex differences in recombination frequency on mouse chromosome 16.
Volume: 1
Issue: 3
Pages: 158-64
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Publication
8100803 | J:12789
First Author: Miller RD
Year: 1993
Journal: Genomics
Title: The mouse severe combined immune deficiency (scid) mutation is closely linked to the B-cell-specific developmental genes VpreB and lambda 5.
Volume: 16
Issue: 3
Pages: 740-4
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Publication
17261847 | J:119495
First Author: Govin J
Year: 2007
Journal: J Cell Biol
Title: Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis.
Volume: 176
Issue: 3
Pages: 283-94
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Publication
1741163 | J:2300
First Author: Charles CH
Year: 1992
Journal: Oncogene
Title: cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.
Volume: 7
Issue: 1
Pages: 187-90
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Publication
13129914 | J:86720
First Author: Nayernia K
Year: 2003
Journal: J Biol Chem
Title: Inactivation of a testis-specific Lis1 transcript in mice prevents spermatid differentiation and causes male infertility.
Volume: 278
Issue: 48
Pages: 48377-85
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Publication
8358171 | J:12908
First Author: Irving NG
Year: 1993
Journal: Mamm Genome
Title: The positions of 12 simple sequence repeat markers relative to reference loci on mouse chromosome 16.
Volume: 4
Issue: 7
Pages: 364-7
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Publication
7842732 | J:24061
First Author: Doggett NA
Year: 1995
Journal: Cytogenet Cell Genet
Title: Report and abstracts of the third international workshop on human chromosome 16 mapping 1994. Pittsburgh, Pennsylvania, May 7-9, 1994.
Volume: 68
Issue: 3-4
Pages: 165-84
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Publication
17130239 | J:118291
First Author: Kress C
Year: 2007
Journal: Mol Cell Biol
Title: Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice.
Volume: 27
Issue: 3
Pages: 1146-57
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Publication
11702780 | J:102097
First Author: Tay J
Year: 2001
Journal: Dev Cell
Title: Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice.
Volume: 1
Issue: 2
Pages: 201-13
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Publication
12060068 | J:80260
First Author: Son WY
Year: 2002
Journal: Dev Growth Differ
Title: Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice.
Volume: 44
Issue: 3
Pages: 181-90
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Publication
9337410 | J:44022
First Author: Matsui M
Year: 1997
Journal: Mamm Genome
Title: Mapping of six germ-cell-specific genes to mouse chromosomes.
Volume: 8
Issue: 11
Pages: 873-4
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Publication
16458478 | J:114923
First Author: Chan WY
Year: 2006
Journal: Genomics
Title: The complexity of antisense transcription revealed by the study of developing male germ cells.
Volume: 87
Issue: 6
Pages: 681-92
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Publication
16024815 | J:100030
First Author: Urano A
Year: 2005
Journal: Mol Cell Biol
Title: Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia.
Volume: 25
Issue: 15
Pages: 6834-45
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Publication
31932482 | J:292511
 
First Author: Gustafson EA
Year: 2020
Journal: Mol Cell Biol
Title: ZFP628 Is a TAF4b-Interacting Transcription Factor Required for Mouse Spermiogenesis.
Volume: 40
Issue: 7
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Publication
30518625 | J:272573
 
First Author: Shima Y
Year: 2018
Journal: Development
Title: Fetal Leydig cells dedifferentiate and serve as adult Leydig stem cells.
Volume: 145
Issue: 23
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Publication
27040500 | J:234504
First Author: Shum EY
Year: 2016
Journal: Cell
Title: The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay.
Volume: 165
Issue: 2
Pages: 382-95
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Publication
18311137 | J:134477
First Author: Puschendorf M
Year: 2008
Journal: Nat Genet
Title: PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos.
Volume: 40
Issue: 4
Pages: 411-20
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Publication
23637336 | J:198562
First Author: Cantù C
Year: 2013
Journal: Development
Title: The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription.
Volume: 140
Issue: 11
Pages: 2377-86
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Publication
21383078 | J:170319
First Author: Yabuta Y
Year: 2011
Journal: J Cell Biol
Title: TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice.
Volume: 192
Issue: 5
Pages: 781-95
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Publication
9244437 | J:42076
First Author: Reeves RH
Year: 1997
Journal: Genomics
Title: High-resolution recombinational map of mouse chromosome 16.
Volume: 43
Issue: 2
Pages: 202-8
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Publication
34059773 | J:306320
First Author: Ho UY
Year: 2021
Journal: Commun Biol
Title: WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis.
Volume: 4
Issue: 1
Pages: 645
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Publication
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First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
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First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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