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Search results 1 to 100 out of 1650 for Prnp

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0.039s
Type Details Score
Gene
Type: gene
Organism: guinea pig
Gene
Type: gene
Organism: pig, domestic
Gene
Type: gene
Organism: deer, mule
Gene
Type: gene
Organism: kudu
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: sheep
Gene
Type: gene
Organism: hamster, Chinese
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Genoud N
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions.
Volume: 101
Issue: 12
Pages: 4198-203
Publication  
First Author: Büdefeld T
Year: 2014
Journal: Behav Brain Res
Title: Deletion of the prion gene Prnp affects offensive aggression in mice.
Volume: 266
Pages: 216-21
Publication
First Author: Lee HP
Year: 2010
Journal: Neuroscience
Title: Altered expression of type 1 inositol 1,4,5-trisphosphate receptor in the Ngsk Prnp deficient mice.
Volume: 167
Issue: 3
Pages: 799-808
Publication  
First Author: Castille J
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Co-invalidation of Prnp and Sprn in FVB/N mice affects reproductive performances and highlight complex biological relationship between PrP and Shadoo.
Volume: 551
Pages: 1-6
GXD Expression    
Probe: MGI:6181350
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191144
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Prnp
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6181350
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191144
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Prnp
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6181350
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191144
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Prnp
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6181350
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191144
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Prnp
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6181350
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191144
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Prnp
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6181350
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191144
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Prnp
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6181350
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191144
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Prnp
Detected: true
Specimen Num: 6
Publication
First Author: Salazar SV
Year: 2017
Journal: J Neurosci
Title: Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease.
Volume: 37
Issue: 38
Pages: 9207-9221
Publication
First Author: Fischer M
Year: 1996
Journal: EMBO J
Title: Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.
Volume: 15
Issue: 6
Pages: 1255-64
Publication
First Author: Flechsig E
Year: 2003
Journal: EMBO J
Title: Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia.
Volume: 22
Issue: 12
Pages: 3095-101
Publication
First Author: Carlson GA
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.
Volume: 91
Issue: 12
Pages: 5690-4
Publication
First Author: Jackson WS
Year: 2014
Journal: PLoS One
Title: Translation of the prion protein mRNA is robust in astrocytes but does not amplify during reactive astrocytosis in the mouse brain.
Volume: 9
Issue: 4
Pages: e95958
Publication
First Author: Urrea L
Year: 2018
Journal: Mol Neurobiol
Title: Involvement of Cellular Prion Protein in α-Synuclein Transport in Neurons.
Volume: 55
Issue: 3
Pages: 1847-1860
Publication
First Author: Asante EA
Year: 2002
Journal: EMBO J
Title: BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein.
Volume: 21
Issue: 23
Pages: 6358-66
Publication
First Author: Hizume M
Year: 2009
Journal: J Biol Chem
Title: Human prion protein (PrP) 219K is converted to PrPSc but shows heterozygous inhibition in variant Creutzfeldt-Jakob disease infection.
Volume: 284
Issue: 6
Pages: 3603-9
Publication
First Author: Moore RC
Year: 1999
Journal: J Mol Biol
Title: Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.
Volume: 292
Issue: 4
Pages: 797-817
Publication  
First Author: Chadi S
Year: 2010
Journal: BMC Genomics
Title: Brain transcriptional stability upon prion protein-encoding gene invalidation in zygotic or adult mouse.
Volume: 11
Pages: 448
Publication
First Author: Martin GR
Year: 2011
Journal: Am J Pathol
Title: Endogenous prion protein attenuates experimentally induced colitis.
Volume: 179
Issue: 5
Pages: 2290-301
Publication
First Author: Albanese V
Year: 2008
Journal: Auton Neurosci
Title: Evidence for prion protein expression in enteroglial cells of the myenteric plexus of mouse intestine.
Volume: 140
Issue: 1-2
Pages: 17-23
Publication
First Author: Shmerling D
Year: 1998
Journal: Cell
Title: Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.
Volume: 93
Issue: 2
Pages: 203-14
Publication
First Author: Tapella L
Year: 2013
Journal: Biochem J
Title: Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases.
Volume: 454
Issue: 3
Pages: 417-25
Publication  
First Author: Striebel JF
Year: 2013
Journal: Neuroscience
Title: Lack of influence of prion protein gene expression on kainate-induced seizures in mice: studies using congenic, coisogenic and transgenic strains.
Volume: 238
Pages: 11-8
Publication
First Author: Takeuchi A
Year: 2013
Journal: J Biol Chem
Title: Characterization of variant Creutzfeldt-Jakob disease prions in prion protein-humanized mice carrying distinct codon 129 genotypes.
Volume: 288
Issue: 30
Pages: 21659-66
Publication
First Author: Rangel A
Year: 2009
Journal: PLoS One
Title: Regulation of GABA(A) and glutamate receptor expression, synaptic facilitation and long-term potentiation in the hippocampus of prion mutant mice.
Volume: 4
Issue: 10
Pages: e7592
Publication
First Author: Kitamoto T
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Humanized prion protein knock-in by Cre-induced site-specific recombination in the mouse.
Volume: 222
Issue: 3
Pages: 742-7
Publication
First Author: Taguchi Y
Year: 2003
Journal: Am J Pathol
Title: Humanized knock-in mice expressing chimeric prion protein showed varied susceptibility to different human prions.
Volume: 163
Issue: 6
Pages: 2585-93
Publication
First Author: Kitamoto T
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Follicular dendritic cell of the knock-in mouse provides a new bioassay for human prions.
Volume: 294
Issue: 2
Pages: 280-6
Publication
First Author: Dias MV
Year: 2016
Journal: Autophagy
Title: PRNP/prion protein regulates the secretion of exosomes modulating CAV1/caveolin-1-suppressed autophagy.
Volume: 12
Issue: 11
Pages: 2113-2128
Publication
First Author: Zabel M
Year: 2009
Journal: Immunology
Title: Perturbation of T-cell development by insertional mutation of a PrP transgene.
Volume: 127
Issue: 2
Pages: 226-36
Publication
First Author: Li A
Year: 2007
Journal: EMBO J
Title: Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice.
Volume: 26
Issue: 11
Pages: 2777-85
Publication
First Author: McCulloch L
Year: 2011
Journal: PLoS Pathog
Title: Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen.
Volume: 7
Issue: 12
Pages: e1002402
Publication
First Author: Le Pichon CE
Year: 2009
Journal: Nat Neurosci
Title: Olfactory behavior and physiology are disrupted in prion protein knockout mice.
Volume: 12
Issue: 1
Pages: 60-9
Publication
First Author: Westaway D
Year: 2011
Journal: PLoS Pathog
Title: Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation.
Volume: 7
Issue: 11
Pages: e1002391
Publication
First Author: Nicolas O
Year: 2007
Journal: FASEB J
Title: Bcl-2 overexpression delays caspase-3 activation and rescues cerebellar degeneration in prion-deficient mice that overexpress amino-terminally truncated prion.
Volume: 21
Issue: 12
Pages: 3107-17
Publication
First Author: Nishida N
Year: 1999
Journal: Lab Invest
Title: A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination.
Volume: 79
Issue: 6
Pages: 689-97
Publication
First Author: Mastrangelo P
Year: 2002
Journal: FEBS Lett
Title: A cluster of familial Creutzfeldt-Jakob disease mutations recapitulate conserved residues in Doppel: a case of molecular mimicry?
Volume: 532
Issue: 1-2
Pages: 21-6
Publication
First Author: Chiesa R
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation.
Volume: 97
Issue: 10
Pages: 5574-9
Publication
First Author: Chiesa R
Year: 2001
Journal: Neurobiol Dis
Title: Primary myopathy and accumulation of PrPSc-like molecules in peripheral tissues of transgenic mice expressing a prion protein insertional mutation.
Volume: 8
Issue: 2
Pages: 279-88
Publication
First Author: Privat N
Year: 2017
Journal: J Biol Chem
Title: Region-specific protein misfolding cyclic amplification reproduces brain tropism of prion strains.
Volume: 292
Issue: 40
Pages: 16688-16696
Publication
First Author: Westaway D
Year: 1991
Journal: Neuron
Title: Paradoxical shortening of scrapie incubation times by expression of prion protein transgenes derived from long incubation period mice.
Volume: 7
Issue: 1
Pages: 59-68
Publication
First Author: Wang X
Year: 2006
Journal: J Biol Chem
Title: The interaction between cytoplasmic prion protein and the hydrophobic lipid core of membrane correlates with neurotoxicity.
Volume: 281
Issue: 19
Pages: 13559-65
Publication
First Author: Chiesa R
Year: 2008
Journal: J Neurosci
Title: Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities.
Volume: 28
Issue: 49
Pages: 13258-67
Publication
First Author: Mata X
Year: 2003
Journal: FEBS Lett
Title: Unexpected high testis-specific transcriptional activity of the cyclin T1 promoter in transgenic mice.
Volume: 549
Issue: 1-3
Pages: 163-6
Publication
First Author: Chiesa R
Year: 2016
Journal: Prion
Title: Transgenic mice recapitulate the phenotypic heterogeneity of genetic prion diseases without developing prion infectivity: Role of intracellular PrP retention in neurotoxicity.
Volume: 10
Issue: 2
Pages: 93-102
Publication
First Author: Bertani I
Year: 2017
Journal: J Neurosci
Title: Inhibition of IL-1β Signaling Normalizes NMDA-Dependent Neurotransmission and Reduces Seizure Susceptibility in a Mouse Model of Creutzfeldt-Jakob Disease.
Volume: 37
Issue: 43
Pages: 10278-10289
Publication
First Author: Watts JC
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein.
Volume: 109
Issue: 9
Pages: 3498-503
Publication
First Author: Giles K
Year: 2015
Journal: J Pharmacol Exp Ther
Title: Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.
Volume: 355
Issue: 1
Pages: 2-12
Publication
First Author: Choi JK
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Amyloid fibrils from the N-terminal prion protein fragment are infectious.
Volume: 113
Issue: 48
Pages: 13851-13856
Publication
First Author: Zanetti F
Year: 2014
Journal: Cardiovasc Res
Title: The cellular prion protein counteracts cardiac oxidative stress.
Volume: 104
Issue: 1
Pages: 93-102
Publication
First Author: De Mario A
Year: 2017
Journal: J Cell Sci
Title: The prion protein regulates glutamate-mediated Ca2+ entry and mitochondrial Ca2+ accumulation in neurons.
Volume: 130
Issue: 16
Pages: 2736-2746
Publication
First Author: Williams SK
Year: 2011
Journal: Am J Pathol
Title: Neuroprotective effects of the cellular prion protein in autoimmune optic neuritis.
Volume: 178
Issue: 6
Pages: 2823-31
Publication
First Author: Masone A
Year: 2023
Journal: iScience
Title: A tetracationic porphyrin with dual anti-prion activity.
Volume: 26
Issue: 9
Pages: 107480
Publication
First Author: Tremblay P
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Doxycycline control of prion protein transgene expression modulates prion disease in mice.
Volume: 95
Issue: 21
Pages: 12580-5
Publication
First Author: Ferreira DG
Year: 2017
Journal: Nat Neurosci
Title: α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B.
Volume: 20
Issue: 11
Pages: 1569-1579
Publication
First Author: Sakudo A
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Tissue- and cell type-specific modification of prion protein (PrP)-like protein Doppel, which affects PrP endoproteolysis.
Volume: 404
Issue: 1
Pages: 523-7
Publication
First Author: Brun A
Year: 2007
Journal: J Gen Virol
Title: Reduced susceptibility to bovine spongiform encephalopathy prions in transgenic mice expressing a bovine PrP with five octapeptide repeats.
Volume: 88
Issue: Pt 6
Pages: 1842-9
Publication
First Author: Yamaguchi N
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Doppel-induced Purkinje cell death is stoichiometrically abrogated by prion protein.
Volume: 319
Issue: 4
Pages: 1247-52
Publication
First Author: Wang M
Year: 2014
Journal: PLoS One
Title: The cellular prion protein negatively regulates phagocytosis and cytokine expression in murine bone marrow-derived macrophages.
Volume: 9
Issue: 7
Pages: e102785
Publication
First Author: Bravard A
Year: 2015
Journal: Nucleic Acids Res
Title: The prion protein is critical for DNA repair and cell survival after genotoxic stress.
Volume: 43
Issue: 2
Pages: 904-16
Publication
First Author: Nazor KE
Year: 2007
Journal: Biochim Biophys Acta
Title: Motor behavioral and neuropathological deficits in mice deficient for normal prion protein expression.
Volume: 1772
Issue: 6
Pages: 645-53
Publication
First Author: Ratté S
Year: 2008
Journal: Neurobiol Dis
Title: Hippocampal bursts caused by changes in NMDA receptor-dependent excitation in a mouse model of variant CJD.
Volume: 32
Issue: 1
Pages: 96-104
Publication
First Author: Hachiya NS
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Microtubules-associated intracellular localization of the NH2-terminal cellular prion protein fragment.
Volume: 313
Issue: 3
Pages: 818-23
Publication
First Author: Amin L
Year: 2016
Journal: J Cell Sci
Title: Characterization of prion protein function by focal neurite stimulation.
Volume: 129
Issue: 20
Pages: 3878-3891
Publication
First Author: Moore RC
Year: 1998
Journal: Nat Genet
Title: Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent.
Volume: 18
Issue: 2
Pages: 118-25
Publication
First Author: Michel B
Year: 2012
Journal: J Immunol
Title: Genetic depletion of complement receptors CD21/35 prevents terminal prion disease in a mouse model of chronic wasting disease.
Volume: 189
Issue: 9
Pages: 4520-7
Publication
First Author: Khalifé M
Year: 2011
Journal: PLoS One
Title: Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesis.
Volume: 6
Issue: 8
Pages: e23253
Publication
First Author: Jouvin-Marche E
Year: 2006
Journal: J Immunol
Title: Overexpression of cellular prion protein induces an antioxidant environment altering T cell development in the thymus.
Volume: 176
Issue: 6
Pages: 3490-7
Publication
First Author: Mallucci GR
Year: 2007
Journal: Neuron
Title: Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice.
Volume: 53
Issue: 3
Pages: 325-35
Publication
First Author: Brandner S
Year: 1996
Journal: Nature
Title: Normal host prion protein necessary for scrapie-induced neurotoxicity.
Volume: 379
Issue: 6563
Pages: 339-43
Publication
First Author: Turnbaugh JA
Year: 2011
Journal: PLoS One
Title: The N-terminal, polybasic region is critical for prion protein neuroprotective activity.
Volume: 6
Issue: 9
Pages: e25675
Publication
First Author: Rial D
Year: 2009
Journal: Neuroscience
Title: Cellular prion protein modulates age-related behavioral and neurochemical alterations in mice.
Volume: 164
Issue: 3
Pages: 896-907
Publication
First Author: Campeau JL
Year: 2013
Journal: PLoS One
Title: Early increase and late decrease of purkinje cell dendritic spine density in prion-infected organotypic mouse cerebellar cultures.
Volume: 8
Issue: 12
Pages: e81776
Publication
First Author: Coulpier M
Year: 2006
Journal: Neuroscience
Title: Axotomy-induced motoneuron death is delayed in mice overexpressing PrPc.
Volume: 141
Issue: 4
Pages: 1827-34
Publication
First Author: Yeh YH
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: A prokaryotic viral sequence is expressed and conserved in mammalian brain.
Volume: 114
Issue: 27
Pages: 7118-7123
Publication
First Author: Hartmann CA
Year: 2013
Journal: FEBS Lett
Title: High levels of cellular prion protein improve astrocyte development.
Volume: 587
Issue: 2
Pages: 238-44
Publication  
First Author: Rial D
Year: 2012
Journal: Neuroscience
Title: Overexpression of cellular prion protein (PrP(C)) prevents cognitive dysfunction and apoptotic neuronal cell death induced by amyloid-β (Aβ₁₋₄₀) administration in mice.
Volume: 215
Pages: 79-89
Publication
First Author: Yun SW
Year: 2007
Journal: Biochem Biophys Res Commun
Title: beta-Amyloid deposition and prion infection in adult primary brain cell long-term culture model.
Volume: 360
Issue: 3
Pages: 520-4
Publication
First Author: Herrmann US
Year: 2015
Journal: PLoS Pathog
Title: Prion infections and anti-PrP antibodies trigger converging neurotoxic pathways.
Volume: 11
Issue: 2
Pages: e1004662
Publication
First Author: Barmada SJ
Year: 2005
Journal: J Neurosci
Title: Visualization of prion infection in transgenic mice expressing green fluorescent protein-tagged prion protein.
Volume: 25
Issue: 24
Pages: 5824-32
Publication
First Author: Biasini E
Year: 2012
Journal: PLoS One
Title: The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells.
Volume: 7
Issue: 3
Pages: e33472