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Search results 1 to 100 out of 1504 for Prnp

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0.037s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Genoud N
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions.
Volume: 101
Issue: 12
Pages: 4198-203
Publication
First Author: Lee HP
Year: 2010
Journal: Neuroscience
Title: Altered expression of type 1 inositol 1,4,5-trisphosphate receptor in the Ngsk Prnp deficient mice.
Volume: 167
Issue: 3
Pages: 799-808
Publication  
First Author: Castille J
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Co-invalidation of Prnp and Sprn in FVB/N mice affects reproductive performances and highlight complex biological relationship between PrP and Shadoo.
Volume: 551
Pages: 1-6
Allele
Name: transgene insertion 28.8, Mouse Clinical Institute
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Publication
First Author: Weber P
Year: 2001
Journal: Eur J Neurosci
Title: Temporally controlled targeted somatic mutagenesis in the mouse brain.
Volume: 14
Issue: 11
Pages: 1777-83
Publication
First Author: Weber P
Year: 2003
Journal: Biol Reprod
Title: Temporally controlled site-specific mutagenesis in the germ cell lineage of the mouse testis.
Volume: 68
Issue: 2
Pages: 553-9
Publication
First Author: Brower CS
Year: 2009
Journal: PLoS One
Title: Ablation of arginylation in the mouse N-end rule pathway: loss of fat, higher metabolic rate, damaged spermatogenesis, and neurological perturbations.
Volume: 4
Issue: 11
Pages: e7757
Publication
First Author: Kretzer NM
Year: 2016
Journal: J Exp Med
Title: RAB43 facilitates cross-presentation of cell-associated antigens by CD8α+ dendritic cells.
Volume: 213
Issue: 13
Pages: 2871-2883
Publication
First Author: Mori M
Year: 2012
Journal: Genesis
Title: Temporally controlled targeted somatic mutagenesis in mouse eye pigment epithelium.
Volume: 50
Issue: 11
Pages: 828-32
Publication
First Author: Thiersch M
Year: 2009
Journal: Eur J Neurosci
Title: Retinal neuroprotection by hypoxic preconditioning is independent of hypoxia-inducible factor-1 alpha expression in photoreceptors.
Volume: 29
Issue: 12
Pages: 2291-302
Publication
First Author: Guo X
Year: 2004
Journal: Genes Dev
Title: Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation.
Volume: 18
Issue: 19
Pages: 2404-17
Publication
First Author: Niu W
Year: 2013
Journal: Nat Cell Biol
Title: In vivo reprogramming of astrocytes to neuroblasts in the adult brain.
Volume: 15
Issue: 10
Pages: 1164-75
Publication
First Author: Ruediger R
Year: 2011
Journal: Mol Cell Biol
Title: Human cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice.
Volume: 31
Issue: 18
Pages: 3832-44
Publication
First Author: Stefanovic M
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: An 11-amino acid beta-hairpin loop in the cytoplasmic domain of band 3 is responsible for ankyrin binding in mouse erythrocytes.
Volume: 104
Issue: 35
Pages: 13972-7
Publication
First Author: Samardzija M
Year: 2008
Journal: Hum Mol Genet
Title: R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal.
Volume: 17
Issue: 2
Pages: 281-92
Publication
First Author: Toyo-oka K
Year: 2004
Journal: Hum Mol Genet
Title: Loss of the Max-interacting protein Mnt in mice results in decreased viability, defective embryonic growth and craniofacial defects: relevance to Miller-Dieker syndrome.
Volume: 13
Issue: 10
Pages: 1057-67
Allele
Name: transgene insertion 1, Carrolee Barlow
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: mutant strain, transgenic
Publication
First Author: Scheel JR
Year: 2003
Journal: Nucleic Acids Res
Title: An inbred 129SvEv GFPCre transgenic mouse that deletes loxP-flanked genes in all tissues.
Volume: 31
Issue: 10
Pages: e57
Publication
First Author: Devlin EE
Year: 2010
Journal: Blood
Title: A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia.
Volume: 116
Issue: 15
Pages: 2826-35
Publication
First Author: de Guzman Strong C
Year: 2006
Journal: J Cell Biol
Title: Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3.
Volume: 175
Issue: 4
Pages: 661-70
Publication
First Author: Hawasli AH
Year: 2007
Journal: Nat Neurosci
Title: Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation.
Volume: 10
Issue: 7
Pages: 880-886
Publication
First Author: Plattner F
Year: 2014
Journal: Neuron
Title: Memory enhancement by targeting Cdk5 regulation of NR2B.
Volume: 81
Issue: 5
Pages: 1070-1083
Publication
First Author: Plattner F
Year: 2015
Journal: Nat Neurosci
Title: The role of ventral striatal cAMP signaling in stress-induced behaviors.
Volume: 18
Issue: 8
Pages: 1094-100
Publication  
First Author: Hernandez A
Year: 2016
Journal: Sci Rep
Title: Cdk5 Modulates Long-Term Synaptic Plasticity and Motor Learning in Dorsolateral Striatum.
Volume: 6
Pages: 29812
Publication
First Author: Hawasli AH
Year: 2009
Journal: PLoS One
Title: Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5.
Volume: 4
Issue: 6
Pages: e5808
Publication
First Author: Yousuf MA
Year: 2016
Journal: J Neurochem
Title: Involvement of aberrant cyclin-dependent kinase 5/p25 activity in experimental traumatic brain injury.
Volume: 138
Issue: 2
Pages: 317-27
Publication  
First Author: Liang Z
Year: 2016
Journal: Nat Commun
Title: The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines.
Volume: 7
Pages: 13282
Allele
Name: transgene insertion 28.4, Mouse Clinical Institute
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Prnp-GFP/cre)1Blw/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdk5/Cdk5 Tg(Prnp-cre/ERT)28.4Ics/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ate1/Ate1 Tg(Prnp-cre/ERT)28.8Ics/?
Background: involves: 129S1/Sv * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-RPS19*R62W)#Dmb/? Tg(Prnp-GFP/cre)1Blw/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-GFP/cre)1Blw/Tg(Prnp-GFP/cre)1Blw
Background: involves: 129S6/SvEvTac
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-Bgeo/ALPP)1Lbe/? Tg(Prnp-cre/ERT)28.4Ics/?
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-cre/ERT)28.4Ics/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Prnp-cre/ERT)28.8Ics/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-Bgeo/ALPP)1Lbe/? Tg(Prnp-cre/ERT)28.8Ics/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Salazar SV
Year: 2017
Journal: J Neurosci
Title: Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease.
Volume: 37
Issue: 38
Pages: 9207-9221
Publication
First Author: Fischer M
Year: 1996
Journal: EMBO J
Title: Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.
Volume: 15
Issue: 6
Pages: 1255-64
Publication
First Author: Flechsig E
Year: 2003
Journal: EMBO J
Title: Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia.
Volume: 22
Issue: 12
Pages: 3095-101
Publication
First Author: Shmerling D
Year: 1998
Journal: Cell
Title: Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.
Volume: 93
Issue: 2
Pages: 203-14
Publication
First Author: Asante EA
Year: 2002
Journal: EMBO J
Title: BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein.
Volume: 21
Issue: 23
Pages: 6358-66
Publication
First Author: Carlson GA
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.
Volume: 91
Issue: 12
Pages: 5690-4
Publication
First Author: Takeuchi A
Year: 2013
Journal: J Biol Chem
Title: Characterization of variant Creutzfeldt-Jakob disease prions in prion protein-humanized mice carrying distinct codon 129 genotypes.
Volume: 288
Issue: 30
Pages: 21659-66
Publication
First Author: Hizume M
Year: 2009
Journal: J Biol Chem
Title: Human prion protein (PrP) 219K is converted to PrPSc but shows heterozygous inhibition in variant Creutzfeldt-Jakob disease infection.
Volume: 284
Issue: 6
Pages: 3603-9
Publication
First Author: Jackson WS
Year: 2014
Journal: PLoS One
Title: Translation of the prion protein mRNA is robust in astrocytes but does not amplify during reactive astrocytosis in the mouse brain.
Volume: 9
Issue: 4
Pages: e95958
Publication
First Author: Li A
Year: 2007
Journal: EMBO J
Title: Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice.
Volume: 26
Issue: 11
Pages: 2777-85
Publication
First Author: Le Pichon CE
Year: 2009
Journal: Nat Neurosci
Title: Olfactory behavior and physiology are disrupted in prion protein knockout mice.
Volume: 12
Issue: 1
Pages: 60-9
Publication
First Author: Zabel M
Year: 2009
Journal: Immunology
Title: Perturbation of T-cell development by insertional mutation of a PrP transgene.
Volume: 127
Issue: 2
Pages: 226-36
Publication
First Author: Moore RC
Year: 1999
Journal: J Mol Biol
Title: Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.
Volume: 292
Issue: 4
Pages: 797-817
Publication
First Author: Albanese V
Year: 2008
Journal: Auton Neurosci
Title: Evidence for prion protein expression in enteroglial cells of the myenteric plexus of mouse intestine.
Volume: 140
Issue: 1-2
Pages: 17-23
Publication  
First Author: Chadi S
Year: 2010
Journal: BMC Genomics
Title: Brain transcriptional stability upon prion protein-encoding gene invalidation in zygotic or adult mouse.
Volume: 11
Pages: 448
Publication
First Author: Martin GR
Year: 2011
Journal: Am J Pathol
Title: Endogenous prion protein attenuates experimentally induced colitis.
Volume: 179
Issue: 5
Pages: 2290-301
Publication
First Author: Westaway D
Year: 1991
Journal: Neuron
Title: Paradoxical shortening of scrapie incubation times by expression of prion protein transgenes derived from long incubation period mice.
Volume: 7
Issue: 1
Pages: 59-68
Publication
First Author: Chiesa R
Year: 2008
Journal: J Neurosci
Title: Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities.
Volume: 28
Issue: 49
Pages: 13258-67
Publication
First Author: Chiesa R
Year: 2001
Journal: Neurobiol Dis
Title: Primary myopathy and accumulation of PrPSc-like molecules in peripheral tissues of transgenic mice expressing a prion protein insertional mutation.
Volume: 8
Issue: 2
Pages: 279-88
Publication
First Author: Chiesa R
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation.
Volume: 97
Issue: 10
Pages: 5574-9
Publication
First Author: Telling GC
Year: 1996
Journal: Genes Dev
Title: Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice.
Volume: 10
Issue: 14
Pages: 1736-50
Publication  
First Author: Striebel JF
Year: 2013
Journal: Neuroscience
Title: Lack of influence of prion protein gene expression on kainate-induced seizures in mice: studies using congenic, coisogenic and transgenic strains.
Volume: 238
Pages: 11-8
Publication
First Author: Westaway D
Year: 2011
Journal: PLoS Pathog
Title: Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation.
Volume: 7
Issue: 11
Pages: e1002391
Publication
First Author: Kitamoto T
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Humanized prion protein knock-in by Cre-induced site-specific recombination in the mouse.
Volume: 222
Issue: 3
Pages: 742-7
Publication
First Author: Kitamoto T
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Follicular dendritic cell of the knock-in mouse provides a new bioassay for human prions.
Volume: 294
Issue: 2
Pages: 280-6
Publication
First Author: Taguchi Y
Year: 2003
Journal: Am J Pathol
Title: Humanized knock-in mice expressing chimeric prion protein showed varied susceptibility to different human prions.
Volume: 163
Issue: 6
Pages: 2585-93
Publication
First Author: Rangel A
Year: 2009
Journal: PLoS One
Title: Regulation of GABA(A) and glutamate receptor expression, synaptic facilitation and long-term potentiation in the hippocampus of prion mutant mice.
Volume: 4
Issue: 10
Pages: e7592
Publication
First Author: Tremblay P
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Doxycycline control of prion protein transgene expression modulates prion disease in mice.
Volume: 95
Issue: 21
Pages: 12580-5
Publication
First Author: Williams SK
Year: 2011
Journal: Am J Pathol
Title: Neuroprotective effects of the cellular prion protein in autoimmune optic neuritis.
Volume: 178
Issue: 6
Pages: 2823-31
Publication
First Author: Asano M
Year: 2006
Journal: Biochem Biophys Res Commun
Title: vCJD prion acquires altered virulence through trans-species infection.
Volume: 342
Issue: 1
Pages: 293-9
Publication
First Author: Kobayashi A
Year: 2007
Journal: J Biol Chem
Title: Cross-sequence transmission of sporadic Creutzfeldt-Jakob disease creates a new prion strain.
Volume: 282
Issue: 41
Pages: 30022-8
Publication
First Author: Chiesa R
Year: 1998
Journal: Neuron
Title: Neurological illness in transgenic mice expressing a prion protein with an insertional mutation.
Volume: 21
Issue: 6
Pages: 1339-51
Publication
First Author: Nicolas O
Year: 2007
Journal: FASEB J
Title: Bcl-2 overexpression delays caspase-3 activation and rescues cerebellar degeneration in prion-deficient mice that overexpress amino-terminally truncated prion.
Volume: 21
Issue: 12
Pages: 3107-17
Publication
First Author: Singh A
Year: 2009
Journal: PLoS One
Title: Prion protein (PrP) knock-out mice show altered iron metabolism: a functional role for PrP in iron uptake and transport.
Volume: 4
Issue: 7
Pages: e6115
Publication
First Author: Li A
Year: 2007
Journal: EMBO J
Title: Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.
Volume: 26
Issue: 2
Pages: 548-58
Publication
First Author: Dossena S
Year: 2008
Journal: Neuron
Title: Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model.
Volume: 60
Issue: 4
Pages: 598-609
Publication
First Author: McCulloch L
Year: 2011
Journal: PLoS Pathog
Title: Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen.
Volume: 7
Issue: 12
Pages: e1002402
Publication
First Author: Herms JW
Year: 2001
Journal: Neurobiol Dis
Title: Prion protein affects Ca2+-activated K+ currents in cerebellar purkinje cells.
Volume: 8
Issue: 2
Pages: 324-30
Publication
First Author: Sigurdson CJ
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis.
Volume: 106
Issue: 1
Pages: 304-9
Publication
First Author: Joshi-Barr S
Year: 2014
Journal: J Virol
Title: De novo prion aggregates trigger autophagy in skeletal muscle.
Volume: 88
Issue: 4
Pages: 2071-82
Publication
First Author: Stewart RS
Year: 2005
Journal: J Biol Chem
Title: A transmembrane form of the prion protein is localized in the Golgi apparatus of neurons.
Volume: 280
Issue: 16
Pages: 15855-64
Publication
First Author: Fioriti L
Year: 2005
Journal: Mol Cell Neurosci
Title: The neurotoxicity of prion protein (PrP) peptide 106-126 is independent of the expression level of PrP and is not mediated by abnormal PrP species.
Volume: 28
Issue: 1
Pages: 165-76
Publication
First Author: Medrano AZ
Year: 2008
Journal: Neurobiol Dis
Title: GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice.
Volume: 31
Issue: 1
Pages: 20-32
Publication
First Author: Stewart RS
Year: 2005
Journal: J Neurosci
Title: Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein.
Volume: 25
Issue: 13
Pages: 3469-77
Publication
First Author: Jeffrey M
Year: 2009
Journal: Am J Pathol
Title: Prion protein with an insertional mutation accumulates on axonal and dendritic plasmalemma and is associated with distinctive ultrastructural changes.
Volume: 175
Issue: 3
Pages: 1208-17
Publication
First Author: Alvarez-Laviada A
Year: 2014
Journal: Biochem J
Title: The inhibition of functional expression of calcium channels by prion protein demonstrates competition with α2δ for GPI-anchoring pathways.
Volume: 458
Issue: 2
Pages: 365-74
Publication
First Author: Ward A
Year: 2019
Journal: PLoS One
Title: Altered distribution, aggregation, and protease resistance of cellular prion protein following intracranial inoculation.
Volume: 14
Issue: 7
Pages: e0219457
Publication
First Author: Senatore A
Year: 2012
Journal: Neuron
Title: Mutant PrP suppresses glutamatergic neurotransmission in cerebellar granule neurons by impairing membrane delivery of VGCC α(2)δ-1 Subunit.
Volume: 74
Issue: 2
Pages: 300-13
Publication
First Author: Wang X
Year: 2006
Journal: J Biol Chem
Title: The interaction between cytoplasmic prion protein and the hydrophobic lipid core of membrane correlates with neurotoxicity.
Volume: 281
Issue: 19
Pages: 13559-65
Publication
First Author: Privat N
Year: 2017
Journal: J Biol Chem
Title: Region-specific protein misfolding cyclic amplification reproduces brain tropism of prion strains.
Volume: 292
Issue: 40
Pages: 16688-16696
Publication
First Author: Flechsig E
Year: 2000
Journal: Neuron
Title: Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice.
Volume: 27
Issue: 2
Pages: 399-408
Publication
First Author: Nishida N
Year: 1999
Journal: Lab Invest
Title: A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination.
Volume: 79
Issue: 6
Pages: 689-97
Publication
First Author: Mastrangelo P
Year: 2002
Journal: FEBS Lett
Title: A cluster of familial Creutzfeldt-Jakob disease mutations recapitulate conserved residues in Doppel: a case of molecular mimicry?
Volume: 532
Issue: 1-2
Pages: 21-6
Publication
First Author: Mata X
Year: 2003
Journal: FEBS Lett
Title: Unexpected high testis-specific transcriptional activity of the cyclin T1 promoter in transgenic mice.
Volume: 549
Issue: 1-3
Pages: 163-6
Publication
First Author: Rutishauser D
Year: 2009
Journal: PLoS One
Title: The comprehensive native interactome of a fully functional tagged prion protein.
Volume: 4
Issue: 2
Pages: e4446
Publication
First Author: Christensen HM
Year: 2010
Journal: Am J Pathol
Title: A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death.
Volume: 176
Issue: 6
Pages: 2695-706
Publication
First Author: Boy J
Year: 2009
Journal: Hum Mol Genet
Title: Reversibility of symptoms in a conditional mouse model of spinocerebellar ataxia type 3.
Volume: 18
Issue: 22
Pages: 4282-95
Publication
First Author: Ma J
Year: 2002
Journal: Science
Title: Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol.
Volume: 298
Issue: 5599
Pages: 1781-5
Publication
First Author: Seelig DM
Year: 2010
Journal: Am J Pathol
Title: Pathogenesis of chronic wasting disease in cervidized transgenic mice.
Volume: 176
Issue: 6
Pages: 2785-97