Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Prospero homeobox protein 1 (Prox1) is transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs [, ]. It is expressed in a subpopulation of endothelial cells that, after budding from veins, gives rise to the mammalian lymphatic system []. Prox1 has been found to be an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Wigle JT |
Year: |
2002 |
Journal: |
EMBO J |
Title: |
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype. |
Volume: |
21 |
Issue: |
7 |
Pages: |
1505-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burke Z |
Year: |
2002 |
Journal: |
Mech Dev |
Title: |
Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm. |
Volume: |
118 |
Issue: |
1-2 |
Pages: |
147-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takeda Y |
Year: |
2013 |
Journal: |
Nucleic Acids Res |
Title: |
Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivation. |
Volume: |
41 |
Issue: |
14 |
Pages: |
6992-7008 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
737
|
Fragment?: |
false |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 12.5 |
Image: |
Prox1 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Prox1 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 14.5 |
Image: |
Prox1 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Prox1 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271124 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 16.5 |
Image: |
Prox1 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Prox1 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271220 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 12.5 |
Image: |
Prox1 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Prox1 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271222 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 14.5 |
Image: |
Prox1 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Prox1 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271224 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 16.5 |
Image: |
Prox1 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Prox1 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754320 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 12.5 |
Image: |
Prox1 - E12.5 |
Note: |
There is strong staining in the ventricular zone of the prethalamus. Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus. |
Specimen Label: |
Prox1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754322 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 14.5 |
Image: |
Prox1 - E14.5 |
Note: |
There is weak staining in the ventricular zone of the prethalamus. Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus. |
Specimen Label: |
Prox1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754324 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 16.5 |
Image: |
Prox1 - E16.5 |
Note: |
There is weak staining in the ventricular zone of the prethalamus. Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus. |
Specimen Label: |
Prox1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753720 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 12.5 |
Image: |
Prox1 - E12.5 |
Note: |
There is strong staining in the mantle zone of the posterior ID. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior ID. |
Specimen Label: |
Prox1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753722 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 14.5 |
Image: |
Prox1 - E14.5 |
Note: |
There is weak staining in the mantle zone of the posterior ID and ARH nucleus. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH and VMH nuclei, the AVH and anterior ID. |
Specimen Label: |
Prox1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753724 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 16.5 |
Image: |
Prox1 - E16.5 |
Note: |
There is moderate staining in the mantle zone of the PH. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH and the DAH. |
Specimen Label: |
Prox1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691319 |
Pattern: |
Non-Uniform |
Stage: |
TS19 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 11.5 |
Image: |
Prox1 - E11.5 |
Note: |
There is moderate staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Prox1 - E11.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271820 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 12.5 |
Image: |
Prox1 - E12.5 |
Note: |
There is strong staining in the mantle zone of the premam zone. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zones and the TT. |
Specimen Label: |
Prox1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271822 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 14.5 |
Image: |
Prox1 - E14.5 |
Note: |
There is strong staining in the mantle zone of the premam zone and weak staining in the TT. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zones. |
Specimen Label: |
Prox1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271824 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 16.5 |
Image: |
Prox1 - E16.5 |
Note: |
There is moderate staining in the mantle zone of the premam zone. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zones. |
Specimen Label: |
Prox1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1690819 |
Pattern: |
Non-Uniform |
Stage: |
TS19 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 11.5 |
Image: |
Prox1 - E11.5 |
Note: |
Staining is strong in the VZ of the TT, moderate in prethalamus, dorsal & ventral POAs, PVH nucleus, posterior ID & premam zone & either absent or ubiquitous in the dorsal thalamus, AVH, anterior ID, VMH & ARH nuclei & mam & supramam zones. |
Specimen Label: |
Prox1 - E11.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753920 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 12.5 |
Image: |
Prox1 - E12.5 |
Note: |
There is strong staining in the ventricular zone of the dorsal and ventral POAs. Staining is either absent or ubiquitous in the ventricular zone of the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Prox1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753922 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 14.5 |
Image: |
Prox1 - E14.5 |
Note: |
There is moderate staining in the ventricular zone of the dorsal and ventral POAs and the posterior ID and weak staining in the AVH. Staining is either absent or ubiquitous in the ventricular zone of the PVH, VMH and ARH nuclei and anterior ID. |
Specimen Label: |
Prox1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753924 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 16.5 |
Image: |
Prox1 - E16.5 |
Note: |
There is moderate staining in the ventricular zone of the dorsal POA and the PH. Staining is either absent or ubiquitous in the ventricular zone of the ventral POA, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH and the DAH. |
Specimen Label: |
Prox1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7414248 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-01-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1906126 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:7414379 |
Age: |
embryonic day 18.5 |
Image: |
1d E18.5 PROX1 |
|
Specimen Label: |
1d E18.5 PROX1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7414248 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-01-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1906126 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:7414379 |
Age: |
embryonic day 18.5 |
Image: |
1d E18.5 PROX1 |
|
Specimen Label: |
1d E18.5 PROX1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691119 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 11.5 |
Image: |
Prox1 - E11.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences. |
Specimen Label: |
Prox1 - E11.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754720 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 12.5 |
Image: |
Prox1 - E12.5 |
Note: |
There is moderate staining in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Prox1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 14.5 |
Image: |
Prox1 - E14.5 |
Note: |
There is weak staining in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Prox1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754724 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 16.5 |
Image: |
Prox1 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Prox1 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271020 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 12.5 |
Image: |
Prox1 - E12.5 |
Note: |
There is strong staining in the ventricular zone of the TT. Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones. |
Specimen Label: |
Prox1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271022 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 14.5 |
Image: |
Prox1 - E14.5 |
Note: |
There is moderate staining in the ventricular zone of the premam zone and the TT. Staining is either absent or ubiquitous in the ventricular zone of the mam and supramam zones. |
Specimen Label: |
Prox1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271024 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 16.5 |
Image: |
Prox1 - E16.5 |
Note: |
There is moderate staining in the ventricular zone of the premam zone. Staining is either absent or ubiquitous in the ventricular zone of the mam and supramam zones. |
Specimen Label: |
Prox1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266520 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 12.5 |
Image: |
Prox1 - E12.5 |
Note: |
There is strong staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences. |
Specimen Label: |
Prox1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266522 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 14.5 |
Image: |
Prox1 - E14.5 |
Note: |
There is moderate staining in the mantle zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the ganglionic eminences. |
Specimen Label: |
Prox1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266524 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 16.5 |
Image: |
Prox1 - E16.5 |
Note: |
There is weak staining in the mantle zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the ganglionic eminences. |
Specimen Label: |
Prox1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1690619 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 11.5 |
Image: |
Prox1 - E11.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus, prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT. |
Specimen Label: |
Prox1 - E11.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 12.5 |
Image: |
Prox1 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Prox1 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Very strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754122 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 14.5 |
Image: |
Prox1 - E14.5 |
Note: |
There is very strong staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus. |
Specimen Label: |
Prox1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442767 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Very strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754124 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450887 |
Age: |
embryonic day 16.5 |
Image: |
Prox1 - E16.5 |
Note: |
There is very strong staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus. |
Specimen Label: |
Prox1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Elsir T |
Year: |
2012 |
Journal: |
Cancer Metastasis Rev |
Title: |
Transcription factor PROX1: its role in development and cancer. |
Volume: |
31 |
Issue: |
3-4 |
Pages: |
793-805 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duncan MK |
Year: |
2002 |
Journal: |
Mech Dev |
Title: |
Prox1 is differentially localized during lens development. |
Volume: |
112 |
Issue: |
1-2 |
Pages: |
195-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tomarev SI |
Year: |
1998 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Characterization of the mouse Prox1 gene. |
Volume: |
248 |
Issue: |
3 |
Pages: |
684-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bermingham-McDonogh O |
Year: |
2006 |
Journal: |
J Comp Neurol |
Title: |
Expression of Prox1 during mouse cochlear development. |
Volume: |
496 |
Issue: |
2 |
Pages: |
172-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaltezioti V |
Year: |
2010 |
Journal: |
PLoS Biol |
Title: |
Prox1 regulates the notch1-mediated inhibition of neurogenesis. |
Volume: |
8 |
Issue: |
12 |
Pages: |
e1000565 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dyer MA |
Year: |
2003 |
Journal: |
Nat Genet |
Title: |
Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. |
Volume: |
34 |
Issue: |
1 |
Pages: |
53-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Harvey NL |
Year: |
2005 |
Journal: |
Nat Genet |
Title: |
Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity. |
Volume: |
37 |
Issue: |
10 |
Pages: |
1072-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kazenwadel J |
Year: |
2023 |
Journal: |
Nature |
Title: |
A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature. |
Volume: |
614 |
Issue: |
7947 |
Pages: |
343-348 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wigle JT |
Year: |
1999 |
Journal: |
Nat Genet |
Title: |
Prox1 function is crucial for mouse lens-fibre elongation. |
Volume: |
21 |
Issue: |
3 |
Pages: |
318-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kazenwadel J |
Year: |
2010 |
Journal: |
Blood |
Title: |
Prox1 expression is negatively regulated by miR-181 in endothelial cells. |
Volume: |
116 |
Issue: |
13 |
Pages: |
2395-401 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lavado A |
Year: |
2007 |
Journal: |
Dev Dyn |
Title: |
Prox1 expression patterns in the developing and adult murine brain. |
Volume: |
236 |
Issue: |
2 |
Pages: |
518-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen X |
Year: |
2008 |
Journal: |
Mol Vis |
Title: |
PCNA interacts with Prox1 and represses its transcriptional activity. |
Volume: |
14 |
|
Pages: |
2076-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Risebro CA |
Year: |
2009 |
Journal: |
Development |
Title: |
Prox1 maintains muscle structure and growth in the developing heart. |
Volume: |
136 |
Issue: |
3 |
Pages: |
495-505 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cho H |
Year: |
2019 |
Journal: |
Circ Res |
Title: |
YAP and TAZ Negatively Regulate Prox1 During Developmental and Pathologic Lymphangiogenesis. |
Volume: |
124 |
Issue: |
2 |
Pages: |
225-242 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goto T |
Year: |
2017 |
Journal: |
FEBS Lett |
Title: |
Liver-specific Prox1 inactivation causes hepatic injury and glucose intolerance in mice. |
Volume: |
591 |
Issue: |
4 |
Pages: |
624-635 |
|
•
•
•
•
•
|
Publication |
First Author: |
Charest-Marcotte A |
Year: |
2010 |
Journal: |
Genes Dev |
Title: |
The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions. |
Volume: |
24 |
Issue: |
6 |
Pages: |
537-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee S |
Year: |
2009 |
Journal: |
Blood |
Title: |
Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate. |
Volume: |
113 |
Issue: |
8 |
Pages: |
1856-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Misra K |
Year: |
2008 |
Journal: |
Dev Dyn |
Title: |
Prox1 regulates a transitory state for interneuron neurogenesis in the spinal cord. |
Volume: |
237 |
Issue: |
2 |
Pages: |
393-402 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wigle JT |
Year: |
1999 |
Journal: |
Cell |
Title: |
Prox1 function is required for the development of the murine lymphatic system. |
Volume: |
98 |
Issue: |
6 |
Pages: |
769-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stachniak TJ |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
Postmitotic Prox1 Expression Controls the Final Specification of Cortical VIP Interneuron Subtypes. |
Volume: |
41 |
Issue: |
39 |
Pages: |
8150-8162 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang J |
Year: |
2005 |
Journal: |
Dev Biol |
Title: |
Prox1 activity controls pancreas morphogenesis and participates in the production of "secondary transition" pancreatic endocrine cells. |
Volume: |
286 |
Issue: |
1 |
Pages: |
182-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kivelä R |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
The transcription factor Prox1 is essential for satellite cell differentiation and muscle fibre-type regulation. |
Volume: |
7 |
|
Pages: |
13124 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johnson NC |
Year: |
2008 |
Journal: |
Genes Dev |
Title: |
Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity. |
Volume: |
22 |
Issue: |
23 |
Pages: |
3282-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seth A |
Year: |
2014 |
Journal: |
Development |
Title: |
Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment. |
Volume: |
141 |
Issue: |
3 |
Pages: |
538-47 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2001-09-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619819 |
|
Stage: |
TS19 |
Assay Id: |
MGI:2149585 |
Age: |
embryonic day 11.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E11.5 +/+ 1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2001-09-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619819 |
|
Stage: |
TS19 |
Assay Id: |
MGI:2149585 |
Age: |
embryonic day 11.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E11.5 -/- 1 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2001-09-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619819 |
|
Stage: |
TS19 |
Assay Id: |
MGI:2149585 |
Age: |
embryonic day 11.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E11.5 +/- 1 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-11-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619825 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5444150 |
Age: |
embryonic day 17.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E17.5 +/+ 1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-11-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619825 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5444150 |
Age: |
embryonic day 17.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E17.5 -/- 1 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2001-09-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619819 |
|
Stage: |
TS19 |
Assay Id: |
MGI:2149585 |
Age: |
embryonic day 11.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E11.5 +/+ 1/10 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2001-09-11 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619819 |
|
Stage: |
TS19 |
Assay Id: |
MGI:2149585 |
Age: |
embryonic day 11.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E11.5 +/+ 1/100 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2001-09-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619819 |
|
Stage: |
TS19 |
Assay Id: |
MGI:2149585 |
Age: |
embryonic day 11.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E11.5 -/- 1/10 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2001-09-11 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619819 |
|
Stage: |
TS19 |
Assay Id: |
MGI:2149585 |
Age: |
embryonic day 11.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E11.5 -/- 1/100 |
|
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2001-09-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619819 |
|
Stage: |
TS19 |
Assay Id: |
MGI:2149585 |
Age: |
embryonic day 11.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E11.5 +/- 1/10 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2001-09-11 |
Strength: |
Not Specified |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619819 |
|
Stage: |
TS19 |
Assay Id: |
MGI:2149585 |
Age: |
embryonic day 11.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E11.5 +/- 1/100 |
|
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-11-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619825 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5444150 |
Age: |
embryonic day 17.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E17.5 +/+ 1/10 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-11-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619825 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5444150 |
Age: |
embryonic day 17.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E17.5 +/+ 1/100 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-11-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619825 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5444150 |
Age: |
embryonic day 17.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E17.5 -/- 1/10 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2149573 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-11-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619825 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5444150 |
Age: |
embryonic day 17.5 |
Image: |
4 |
|
Specimen Label: |
Prox1 E17.5 -/- 1/100 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baxter SA |
Year: |
2011 |
Journal: |
Biochim Biophys Acta |
Title: |
Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein. |
Volume: |
1813 |
Issue: |
1 |
Pages: |
201-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bunk EC |
Year: |
2016 |
Journal: |
Stem Cells |
Title: |
Prox1 Is Required for Oligodendrocyte Cell Identity in Adult Neural Stem Cells of the Subventricular Zone. |
Volume: |
34 |
Issue: |
8 |
Pages: |
2115-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paul L |
Year: |
2016 |
Journal: |
Diabetes |
Title: |
Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-Cells. |
Volume: |
65 |
Issue: |
3 |
Pages: |
687-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Westmoreland JJ |
Year: |
2012 |
Journal: |
Gastroenterology |
Title: |
Pancreas-specific deletion of Prox1 affects development and disrupts homeostasis of the exocrine pancreas. |
Volume: |
142 |
Issue: |
4 |
Pages: |
999-1009.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyoshi G |
Year: |
2015 |
Journal: |
J Neurosci |
Title: |
Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons. |
Volume: |
35 |
Issue: |
37 |
Pages: |
12869-89 |
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Publication |
First Author: |
Mishima K |
Year: |
2007 |
Journal: |
Mol Biol Cell |
Title: |
Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades. |
Volume: |
18 |
Issue: |
4 |
Pages: |
1421-9 |
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Publication |
First Author: |
Srinivasan RS |
Year: |
2010 |
Journal: |
Genes Dev |
Title: |
The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. |
Volume: |
24 |
Issue: |
7 |
Pages: |
696-707 |
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Publication |
First Author: |
Kato K |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Prox1 Inhibits Proliferation and Is Required for Differentiation of the Oligodendrocyte Cell Lineage in the Mouse. |
Volume: |
10 |
Issue: |
12 |
Pages: |
e0145334 |
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Publication |
First Author: |
Audette DS |
Year: |
2016 |
Journal: |
Development |
Title: |
Prox1 and fibroblast growth factor receptors form a novel regulatory loop controlling lens fiber differentiation and gene expression. |
Volume: |
143 |
Issue: |
2 |
Pages: |
318-28 |
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Publication |
First Author: |
Wiener Z |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
Prox1 promotes expansion of the colorectal cancer stem cell population to fuel tumor growth and ischemia resistance. |
Volume: |
8 |
Issue: |
6 |
Pages: |
1943-1956 |
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