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Search results 1 to 100 out of 2044 for Prrx1

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0.043s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression  
Probe: MGI:3821239
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2622022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825671
Age: embryonic day 14.5
Image: 5 Prrx1
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3821239
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2622022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825671
Age: embryonic day 14.5
Image: Additional file 4 Prrx1
Detected: true
Specimen Num: 2
Publication
First Author: Wilk K
Year: 2017
Journal: Stem Cell Reports
Title: Postnatal Calvarial Skeletal Stem Cells Expressing PRX1 Reside Exclusively in the Calvarial Sutures and Are Required for Bone Regeneration.
Volume: 8
Issue: 4
Pages: 933-946
Publication
First Author: Akiyama H
Year: 2002
Journal: Genes Dev
Title: The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6.
Volume: 16
Issue: 21
Pages: 2813-28
Publication
First Author: Canalis E
Year: 2010
Journal: Endocrinology
Title: Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice.
Volume: 151
Issue: 8
Pages: 3490-501
Publication
First Author: Vickerman L
Year: 2011
Journal: Dev Biol
Title: Shox2 function couples neural, muscular and skeletal development in the proximal forelimb.
Volume: 350
Issue: 2
Pages: 323-36
Publication
First Author: Itou J
Year: 2012
Journal: Development
Title: Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos.
Volume: 139
Issue: 9
Pages: 1620-9
Publication  
First Author: Soldatov R
Year: 2019
Journal: Science
Title: Spatiotemporal structure of cell fate decisions in murine neural crest.
Volume: 364
Issue: 6444
Publication
First Author: Reichert M
Year: 2013
Journal: Genes Dev
Title: The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis.
Volume: 27
Issue: 3
Pages: 288-300
Publication
First Author: Norris RA
Year: 2000
Journal: Mamm Genome
Title: Human PRRX1 and PRRX2 genes: cloning, expression, genomic localization, and exclusion as disease genes for Nager syndrome.
Volume: 11
Issue: 11
Pages: 1000-5
Publication
First Author: Martin JF
Year: 2000
Journal: Genesis
Title: Identification of a prx1 limb enhancer.
Volume: 26
Issue: 4
Pages: 225-9
Publication  
First Author: Figueroa CA
Year: 2020
Journal: Bone
Title: Deletion of α-Synuclein in Prrx1-positive cells causes partial loss of function in the central nervous system (CNS) but does not affect ovariectomy induced bone loss.
Volume: 137
Pages: 115428
Publication
First Author: Zhang Y
Year: 2020
Journal: Dev Dyn
Title: Cruciate ligament, patellar tendon, and patella formation involves differential cellular sources and dynamics as joint cavitation proceeds.
Volume: 249
Issue: 6
Pages: 711-722
Allele
Name: transgene insertion 1, Clifford J Tabin
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Allele
Name: transgene insertion 1, Shunichi Murakami
Allele Type: Transgenic
Attribute String: Inducible, Recombinase, Reporter
Publication categories: ProxyCollection
Publication
First Author: Araldi E
Year: 2011
Journal: Nat Med
Title: Lack of HIF-2α in limb bud mesenchyme causes a modest and transient delay of endochondral bone development.
Volume: 17
Issue: 1
Pages: 25-6; author reply 27-9
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: transgenic, mutant strain, congenic
Publication
First Author: Cao F
Year: 2017
Journal: Hum Mol Genet
Title: Generalized metabolic bone disease and fracture risk in Rothmund-Thomson syndrome.
Volume: 26
Issue: 16
Pages: 3046-3055
Publication
First Author: Johnson ET
Year: 2008
Journal: Dev Dyn
Title: Role for primary cilia in the regulation of mouse ovarian function.
Volume: 237
Issue: 8
Pages: 2053-60
Publication
First Author: Kobayashi H
Year: 2013
Journal: J Biol Chem
Title: Transcriptional induction of ADAMTS5 protein by nuclear factor-κB (NF-κB) family member RelA/p65 in chondrocytes during osteoarthritis development.
Volume: 288
Issue: 40
Pages: 28620-9
Genotype
Symbol: Bmp2/Bmp2 Tg(Prrx1-cre)1Cjt/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Flt1/Flt1 Tg(Prrx1-cre)1Cjt/?
Background: involves: C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kdr/Kdr Tg(Prrx1-cre)1Cjt/?
Background: involves: C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Wls/Wls Tg(Prrx1-cre)1Cjt/?
Background: involves: C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hivep3/Hivep3 Tg(Prrx1-cre)1Cjt/?
Background: involves: C57BL/6 * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Prrx1-cre)1Cjt/? Usp34/Usp34
Background: involves: C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Prrx1-cre)1Cjt/?
Background: involves: C57BL/6J * C57BL/6NTac * SJL/J
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Leavitt T
Year: 2020
Journal: Cell Rep
Title: Prrx1 Fibroblasts Represent a Pro-fibrotic Lineage in the Mouse Ventral Dermis.
Volume: 33
Issue: 6
Pages: 108356
Publication  
First Author: Li T
Year: 2019
Journal: Sci Transl Med
Title: TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.
Volume: 11
Issue: 491
Publication      
First Author: Tolkachov A
Year: 2018
Journal: Mol Cell Biol
Title: Loss of the hematopoietic stem cell factor GATA2 in the osteogenic lineage impairs trabecularization and mechanical strength of bone.
Publication  
First Author: Chen X
Year: 2018
Journal: Bone Res
Title: RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation.
Volume: 6
Pages: 34
Publication
First Author: Ailixiding M
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Pivotal role of Sirt6 in the crosstalk among ageing, metabolic syndrome and osteoarthritis.
Volume: 466
Issue: 3
Pages: 319-26
Publication
First Author: El Khassawna T
Year: 2012
Journal: Bone
Title: Deterioration of fracture healing in the mouse model of NF1 long bone dysplasia.
Volume: 51
Issue: 4
Pages: 651-60
Publication
First Author: Lapinski PE
Year: 2013
Journal: Dis Model Mech
Title: Deletion of SHP-2 in mesenchymal stem cells causes growth retardation, limb and chest deformity, and calvarial defects in mice.
Volume: 6
Issue: 6
Pages: 1448-58
Publication
First Author: Tsuji K
Year: 2006
Journal: Nat Genet
Title: BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing.
Volume: 38
Issue: 12
Pages: 1424-9
Publication  
First Author: Yu YH
Year: 2018
Journal: Bone
Title: In vivo identification of Bmp2-correlation networks during fracture healing by means of a limb-specific conditional inactivation of Bmp2.
Volume: 116
Pages: 103-110
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Bobick BE
Year: 2012
Journal: J Cell Sci
Title: Shox2 regulates progression through chondrogenesis in the mouse proximal limb.
Volume: 125
Issue: Pt 24
Pages: 6071-83
Publication
First Author: Fan Y
Year: 2016
Journal: FASEB J
Title: Parathyroid hormone 1 receptor is essential to induce FGF23 production and maintain systemic mineral ion homeostasis.
Volume: 30
Issue: 1
Pages: 428-40
Publication
First Author: Schmidt K
Year: 2009
Journal: Mol Cell Biol
Title: Cholesterol metabolism: the main pathway acting downstream of cytochrome P450 oxidoreductase in skeletal development of the limb.
Volume: 29
Issue: 10
Pages: 2716-29
Publication
First Author: Soshnikova N
Year: 2010
Journal: Dev Cell
Title: Functional analysis of CTCF during mammalian limb development.
Volume: 19
Issue: 6
Pages: 819-30
Publication
First Author: Hildebrand L
Year: 2019
Journal: Dev Dyn
Title: Limb specific Acvr1-knockout during embryogenesis in mice exhibits great toe malformation as seen in Fibrodysplasia Ossificans Progressiva (FOP).
Volume: 248
Issue: 5
Pages: 396-403
Publication
First Author: Miyajima D
Year: 2012
Journal: J Biol Chem
Title: Profilin1 regulates sternum development and endochondral bone formation.
Volume: 287
Issue: 40
Pages: 33545-53
Publication  
First Author: Sun W
Year: 2016
Journal: Bone
Title: Rictor is required for optimal bone accrual in response to anti-sclerostin therapy in the mouse.
Volume: 85
Pages: 1-8
Publication
First Author: Chen J
Year: 2015
Journal: J Bone Miner Res
Title: mTORC2 signaling promotes skeletal growth and bone formation in mice.
Volume: 30
Issue: 2
Pages: 369-78
Genotype
Symbol: Sox9/Sox9<+> Tg(Prrx1-cre)1Cjt/?
Background: involves: 129S7/SvEvBrd * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox9/Sox9 Tg(Prrx1-cre)1Cjt/?
Background: involves: 129S7/SvEvBrd * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Vegfa/Vegfa Tg(Prrx1-cre)1Cjt/?
Background: involves: 129/Sv * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Prrx1-cre/ERT2,-EGFP)1Smkm/Tg(Prrx1-cre/ERT2,-EGFP)1Smkm
Background: involves: C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Prrx1-cre)1Cjt/?
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Osr1/Osr1 Tg(Prrx1-cre)1Cjt/?
Background: involves: 129S1/Sv * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Reck/Reck Tg(Prrx1-cre)1Cjt/?
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * FVB/N * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sp7/Sp7 Tg(Prrx1-cre)1Cjt/?
Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nf1/Nf1 Tg(Prrx1-cre)1Cjt/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nf1/Nf1 Tg(Prrx1-cre)1Cjt/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Prrx1-cre)1Cjt/?
Background: involves: 129S1/Sv * C57BL/6J * SJL/J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Smad4/Smad4 Tg(Prrx1-cre)1Cjt/?
Background: involves: C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ctdnep1/Ctdnep1 Tg(Prrx1-cre)1Cjt/?
Background: involves: C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Por/Por Tg(Prrx1-cre)1Cjt/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ctcf/Ctcf Tg(Prrx1-cre)1Cjt/?
Background: involves: 129P2/OlaHsd * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mirc1/Mirc1 Mirc3/Mirc3 Tg(Prrx1-cre)1Cjt/?
Background: involves: 129S4/SvJae * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Shox2/Shox2 Tg(Prrx1-cre)1Cjt/?
Background: involves: 129S2/SvPas * C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Durland JL
Year: 2008
Journal: J Anat
Title: Visualizing the lateral somitic frontier in the Prx1Cre transgenic mouse.
Volume: 212
Issue: 5
Pages: 590-602
Publication
First Author: Mora-Blanco EL
Year: 2014
Journal: Oncogene
Title: Activation of β-catenin/TCF targets following loss of the tumor suppressor SNF5.
Volume: 33
Issue: 7
Pages: 933-8
Publication
First Author: Logan M
Year: 2002
Journal: Genesis
Title: Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer.
Volume: 33
Issue: 2
Pages: 77-80
Publication
First Author: Yang Y
Year: 2020
Journal: Nucleic Acids Res
Title: Phosphorylation of Msx1 promotes cell proliferation through the Fgf9/18-MAPK signaling pathway during embryonic limb development.
Volume: 48
Issue: 20
Pages: 11452-11467
Publication
First Author: Solomon LA
Year: 2013
Journal: Hum Mol Genet
Title: Targeted loss of the ATR-X syndrome protein in the limb mesenchyme of mice causes brachydactyly.
Volume: 22
Issue: 24
Pages: 5015-25
Publication  
First Author: Xu Z
Year: 2017
Journal: Nat Commun
Title: SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts.
Volume: 8
Pages: 14570
Publication
First Author: Wang C
Year: 2016
Journal: J Clin Invest
Title: NOTCH signaling in skeletal progenitors is critical for fracture repair.
Volume: 126
Issue: 4
Pages: 1471-81
Publication
First Author: Valasek P
Year: 2011
Journal: Dev Biol
Title: Cellular and molecular investigations into the development of the pectoral girdle.
Volume: 357
Issue: 1
Pages: 108-16
Publication
First Author: Rallis C
Year: 2003
Journal: Development
Title: Tbx5 is required for forelimb bud formation and continued outgrowth.
Volume: 130
Issue: 12
Pages: 2741-51
Publication
First Author: Minguillon C
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Tbx4/5 gene duplication and the origin of vertebrate paired appendages.
Volume: 106
Issue: 51
Pages: 21726-30
Publication
First Author: Minguillon C
Year: 2005
Journal: Dev Cell
Title: Tbx5 and Tbx4 are not sufficient to determine limb-specific morphologies but have common roles in initiating limb outgrowth.
Volume: 8
Issue: 1
Pages: 75-84
Publication
First Author: Mellis D
Year: 2021
Journal: PLoS Genet
Title: Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis.
Volume: 17
Issue: 4
Pages: e1009275
Publication
First Author: Lee SY
Year: 2018
Journal: J Clin Invest
Title: Notch signaling suppresses glucose metabolism in mesenchymal progenitors to restrict osteoblast differentiation.
Volume: 128
Issue: 12
Pages: 5573-5586
Publication
First Author: Guo L
Year: 2018
Journal: J Cell Biol
Title: Kindlin-2 regulates mesenchymal stem cell differentiation through control of YAP1/TAZ.
Volume: 217
Issue: 4
Pages: 1431-1451
Publication  
First Author: Sutter PA
Year: 2021
Journal: Bone
Title: Mesenchyme-specific loss of Dot1L histone methyltransferase leads to skeletal dysplasia phenotype in mice.
Volume: 142
Pages: 115677
Publication
First Author: Chen Q
Year: 2015
Journal: J Bone Miner Res
Title: Mesenchymal Deletion of Histone Demethylase NO66 in Mice Promotes Bone Formation.
Volume: 30
Issue: 9
Pages: 1608-17
Publication
First Author: Summers MA
Year: 2018
Journal: Hum Mol Genet
Title: Dietary intervention rescues myopathy associated with neurofibromatosis type 1.
Volume: 27
Issue: 4
Pages: 577-588
Publication
First Author: Dudakovic A
Year: 2015
Journal: J Biol Chem
Title: Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2.
Volume: 290
Issue: 46
Pages: 27604-17
Publication      
First Author: Ouyang Z
Year: 2013
Journal: Bone
Title: Prx1 and 3.2kb Col1a1 promoters target distinct bone cell populations in transgenic mice.
Publication
First Author: Shung CY
Year: 2012
Journal: Hum Mol Genet
Title: Disruption of a Sox9-β-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II.
Volume: 21
Issue: 21
Pages: 4628-44
Publication
First Author: Abula K
Year: 2015
Journal: FEBS Lett
Title: Elimination of BMP7 from the developing limb mesenchyme leads to articular cartilage degeneration and synovial inflammation with increased age.
Volume: 589
Issue: 11
Pages: 1240-8
Publication
First Author: Tsuji K
Year: 2010
Journal: J Orthop Res
Title: Conditional deletion of BMP7 from the limb skeleton does not affect bone formation or fracture repair.
Volume: 28
Issue: 3
Pages: 384-9
Publication  
First Author: Intini G
Year: 2015
Journal: Bone
Title: Dkk1 haploinsufficiency requires expression of Bmp2 for bone anabolic activity.
Volume: 75
Pages: 151-60
Strain
Attribute String: congenic, mutant strain, targeted mutation
Publication
First Author: Longobardi L
Year: 2012
Journal: Dev Cell
Title: TGF-β type II receptor/MCP-5 axis: at the crossroad between joint and growth plate development.
Volume: 23
Issue: 1
Pages: 71-81
Publication
First Author: Seo HS
Year: 2009
Journal: Dev Biol
Title: Tgfbr2 is required for development of the skull vault.
Volume: 334
Issue: 2
Pages: 481-90
Publication
First Author: Seo HS
Year: 2007
Journal: Dev Biol
Title: Deletion of Tgfbr2 in Prx1-cre expressing mesenchyme results in defects in development of the long bones and joints.
Volume: 310
Issue: 2
Pages: 304-16
Publication
First Author: Smaldone S
Year: 2016
Journal: J Bone Miner Res
Title: Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche.
Volume: 31
Issue: 1
Pages: 86-97
Publication
First Author: Killian ML
Year: 2016
Journal: FASEB J
Title: Scleraxis is required for the development of a functional tendon enthesis.
Volume: 30
Issue: 1
Pages: 301-11
Publication
First Author: Amarilio R
Year: 2007
Journal: Development
Title: HIF1alpha regulation of Sox9 is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeletogenesis.
Volume: 134
Issue: 21
Pages: 3917-28
Publication
First Author: Chang L
Year: 2018
Journal: Am J Pathol
Title: Lineage-Specific Wnt Reporter Elucidates Mesenchymal Wnt Signaling during Bone Repair.
Volume: 188
Issue: 10
Pages: 2155-2163
Publication
First Author: Wang L
Year: 2018
Journal: PLoS Biol
Title: H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells.
Volume: 16
Issue: 11
Pages: e2006522
Publication
First Author: Dasgupta K
Year: 2019
Journal: Dev Biol
Title: Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling.
Volume: 455
Issue: 2
Pages: 434-448
Publication
First Author: Kaludjerovic J
Year: 2017
Journal: FASEB J
Title: Klotho expression in long bones regulates FGF23 production during renal failure.
Volume: 31
Issue: 5
Pages: 2050-2064