| Type |
Details |
Score |
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
180
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Regadas I |
| Year: |
2014 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Dual role of Tlx3 as modulator of Prrxl1 transcription and phosphorylation. |
| Volume: |
1839 |
| Issue: |
11 |
| Pages: |
1121-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Soares-Dos-Reis R |
| Year: |
2017 |
| Journal: |
Biochem J |
| Title: |
A role for prolyl isomerase PIN1 in the phosphorylation-dependent modulation of PRRXL1 function. |
| Volume: |
474 |
| Issue: |
5 |
| Pages: |
683-697 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rebelo S |
| Year: |
2009 |
| Journal: |
Int J Dev Biol |
| Title: |
Expression of a Prrxl1 alternative splice variant during the development of the mouse nociceptive system. |
| Volume: |
53 |
| Issue: |
7 |
| Pages: |
1089-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rebelo S |
| Year: |
2010 |
| Journal: |
Dev Dyn |
| Title: |
Prrxl1 is required for the generation of a subset of nociceptive glutamatergic superficial spinal dorsal horn neurons. |
| Volume: |
239 |
| Issue: |
6 |
| Pages: |
1684-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Regadas I |
| Year: |
2013 |
| Journal: |
J Biol Chem |
| Title: |
Several cis-regulatory elements control mRNA stability, translation efficiency, and expression pattern of Prrxl1 (paired related homeobox protein-like 1). |
| Volume: |
288 |
| Issue: |
51 |
| Pages: |
36285-301 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baltar J |
| Year: |
2024 |
| Journal: |
Neural Dev |
| Title: |
Neph1 is required for neurite branching and is negatively regulated by the PRRXL1 homeodomain factor in the developing spinal cord dorsal horn. |
| Volume: |
19 |
| Issue: |
1 |
| Pages: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181422 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689419 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:6191152 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table S2 - E11.5 - Prrxl1 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181422 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689421 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:6191152 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
Table S2 - E13.5 - Prrxl1 |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181422 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689424 |
|
| Stage: |
TS24 |
| Assay Id: |
MGI:6191152 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
Table S2 - E15.5 - Prrxl1 |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181422 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689426 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:6191152 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
Table S2 - E18.5 - Prrxl1 |
| Detected: |
false |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181422 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6191152 |
| Age: |
postnatal day 4 |
|
|
| Specimen Label: |
Table S2 - P4 - Prrxl1 |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181422 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6191152 |
| Age: |
postnatal day 14 |
|
|
| Specimen Label: |
Table S2 - P14 - Prrxl1 |
| Detected: |
false |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181422 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6191152 |
| Age: |
postnatal day 28 |
|
|
| Specimen Label: |
Table S2 - P28 - Prrxl1 |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7766941 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1666822 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7767882 |
| Age: |
embryonic day 14.5 |
| Image: |
2Db |
| Note: |
No difference was observed in the dorsal root ganglion of the Prrxl1 knockout compared with wild-type. |
| Specimen Label: |
2Db |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7766941 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1666824 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:7767882 |
| Age: |
embryonic day 16.5 |
| Image: |
2Dd |
| Note: |
Expression did not change in the Prrxl1 knockout as compared with wild-type embryos at E16.5. |
| Specimen Label: |
2Dd |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7766941 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3579024 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:7767882 |
| Age: |
embryonic day 16.5 |
| Image: |
2Dd |
| Note: |
Expression did not change in the Prrxl1 knockout as compared with wild-type embryos at E16.5. |
| Specimen Label: |
2Dd |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
263
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
220
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7766941 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-11-06 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3579022 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:7767882 |
| Age: |
embryonic day 14.5 |
| Image: |
1Bc |
| Note: |
Less colocalization (arrows) with Prrxl1 in glutamatergic neurons was observed. Cells that did not co-localize expression were marked with asterisks. |
| Specimen Label: |
1Bc |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5583039 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3579022 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7767885 |
| Age: |
embryonic day 14.5 |
| Image: |
1Bc2 |
| Note: |
Prrxl1 (Drgx) is a marker for dILB glutamatergic neuronal cell population. Some co-localization was observed with Kirrel1. |
| Specimen Label: |
1Bc2 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6286144 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-05 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3579026 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6286215 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Authors report a dramatic reduction in expression of the Prrxl1-b isoform compared to Prrxl1 mRNA in the spinal cord at E18.5. |
| Specimen Label: |
3D |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Yu-Qiang Ding |
| Allele Type: |
Transgenic |
| Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Prrxl1-cre/ERT2)1Yqd/? |
| Background: |
involves: FVB/N |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Y |
| Year: |
2018 |
| Journal: |
Nat Commun |
| Title: |
TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
1529 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao X |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
PKCε SUMOylation Is Required for Mediating the Nociceptive Signaling of Inflammatory Pain. |
| Volume: |
33 |
| Issue: |
1 |
| Pages: |
108191 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Monteiro CB |
| Year: |
2014 |
| Journal: |
FEBS Lett |
| Title: |
Paired related homeobox protein-like 1 (Prrxl1) controls its own expression by a transcriptional autorepression mechanism. |
| Volume: |
588 |
| Issue: |
18 |
| Pages: |
3475-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hu ZL |
| Year: |
2012 |
| Journal: |
Genesis |
| Title: |
Inducible Prrxl1-CreER(T2) recombination activity in the somatosensory afferent pathway. |
| Volume: |
50 |
| Issue: |
7 |
| Pages: |
552-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Q |
| Year: |
2023 |
| Journal: |
Cell Rep |
| Title: |
hnRNPA1 SUMOylation promotes cold hypersensitivity in chronic inflammatory pain by stabilizing TRPA1 mRNA. |
| Volume: |
42 |
| Issue: |
11 |
| Pages: |
113401 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hu L |
| Year: |
2014 |
| Journal: |
Mol Brain |
| Title: |
A mouse line for inducible and reversible silencing of specific neurons. |
| Volume: |
7 |
|
| Pages: |
68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Soares-dos-Reis R |
| Year: |
2014 |
| Journal: |
Biochem J |
| Title: |
Ser¹¹⁹ phosphorylation modulates the activity and conformation of PRRXL1, a homeodomain transcription factor. |
| Volume: |
459 |
| Issue: |
3 |
| Pages: |
441-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerhard DS |
| Year: |
2004 |
| Journal: |
Genome Res |
| Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| Volume: |
14 |
| Issue: |
10B |
| Pages: |
2121-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Church DM |
| Year: |
2009 |
| Journal: |
PLoS Biol |
| Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
| Volume: |
7 |
| Issue: |
5 |
| Pages: |
e1000112 |
|
•
•
•
•
•
|