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Search results 1 to 99 out of 99 for Prtn3

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
5657 | PRTN3
Type: gene
Organism: human
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Gene
749895 | PRTN3
Type: gene
Organism: chimpanzee
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Gene
100298591 | PRTN3
Type: gene
Organism: cattle
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Gene
721131 | PRTN3
Type: gene
Organism: macaque, rhesus
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Gene
448597 | prtn3
Type: gene
Organism: frog, western clawed
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Gene
314615 | Prtn3
Type: gene
Organism: rat
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Protein Coding Gene
MGI:893580 | Prtn3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
9925946 | J:53137
First Author: Sturrock A
Year: 1998
Journal: Cytogenet Cell Genet
Title: Characterization and localization of the genes for mouse proteinase-3 (Prtn3) and neutrophil elastase (Ela2).
Volume: 83
Issue: 1-2
Pages: 104-8
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Publication
18568075 | J:137674
First Author: Kessenbrock K
Year: 2008
Journal: J Clin Invest
Title: Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin.
Volume: 118
Issue: 7
Pages: 2438-47
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Publication
22213227 | J:187789
First Author: Mankan AK
Year: 2012
Journal: Eur J Immunol
Title: The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.
Volume: 42
Issue: 3
Pages: 710-5
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Publication
32002713 | J:296047
First Author: Mirea AM
Year: 2020
Journal: Inflammation
Title: Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD.
Volume: 43
Issue: 3
Pages: 1054-1064
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Publication
21160041 | J:168769
First Author: Croker BA
Year: 2011
Journal: J Immunol
Title: Neutrophils require SHP1 to regulate IL-1β production and prevent inflammatory skin disease.
Volume: 186
Issue: 2
Pages: 1131-9
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Publication
37463581 | J:341387
First Author: Ugur M
Year: 2023
Journal: Immunity
Title: Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks.
Volume: 56
Issue: 8
Pages: 1778-1793.e10
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Publication
21464320 | J:171365
First Author: Mankan AK
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: TNF-alpha-dependent loss of IKKbeta-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis.
Volume: 108
Issue: 16
Pages: 6567-72
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Protein Coding Gene
MGP_CAROLIEiJ_G0015547 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017465 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017443 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017404 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017405 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017228 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_893580 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017200 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017306 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017377 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017326 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017900 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016576 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016855 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030960 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016365 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9187364 | J:40592
First Author: Jenne DE
Year: 1997
Journal: FEBS Lett
Title: Cloning and functional expression of the murine homologue of proteinase 3: implications for the design of murine models of vasculitis.
Volume: 408
Issue: 2
Pages: 187-90
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Publication
30392974 | J:310680
First Author: Karatepe K
Year: 2018
Journal: Stem Cell Reports
Title: Proteinase 3 Limits the Number of Hematopoietic Stem and Progenitor Cells in Murine Bone Marrow.
Volume: 11
Issue: 5
Pages: 1092-1105
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Publication
11290610 | J:68804
First Author: Lutz PG
Year: 2001
Journal: Blood
Title: Myeloblastin is an Myb target gene: mechanisms of regulation in myeloid leukemia cells growth-arrested by retinoic acid.
Volume: 97
Issue: 8
Pages: 2449-56
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Publication
15150076 | J:92697
First Author: Pfister H
Year: 2004
Journal: Blood
Title: Antineutrophil cytoplasmic autoantibodies against the murine homolog of proteinase 3 (Wegener autoantigen) are pathogenic in vivo.
Volume: 104
Issue: 5
Pages: 1411-8
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Publication
20015271 | J:158412
First Author: Primo VC
Year: 2010
Journal: Clin Exp Immunol
Title: Anti-PR3 immune responses induce segmental and necrotizing glomerulonephritis.
Volume: 159
Issue: 3
Pages: 327-37
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Publication
26436651 | J:227486
First Author: Millet A
Year: 2015
Journal: J Clin Invest
Title: Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis.
Volume: 125
Issue: 11
Pages: 4107-21
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GXD Expression
GXD Expression
     
Probe: MGI:2657299
Assay Type: Northern blot
Annotation Date: 2003-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:2658760
Age: embryonic day 19.0
Specimen Label: C/EBPa+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2657299
Assay Type: Northern blot
Annotation Date: 2003-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:2658760
Age: embryonic day 19.0
Specimen Label: C/EBPa-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2657299
Assay Type: Northern blot
Annotation Date: 2003-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:2658760
Age: embryonic day 19.0
Specimen Label: PU.1+/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2657299
Assay Type: Northern blot
Annotation Date: 2003-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:2658760
Age: embryonic day 19.0
Specimen Label: PU.1-/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3603591
Assay Type: RT-PCR
Annotation Date: 2005-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3603610
Age: embryonic day 1.0
Specimen Label: 2-cell
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3603591
Assay Type: RT-PCR
Annotation Date: 2005-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3603610
Age: embryonic day 2.5
Specimen Label: 8-cell
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3603591
Assay Type: RT-PCR
Annotation Date: 2005-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3603610
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3603591
Assay Type: RT-PCR
Annotation Date: 2005-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3603610
Age: embryonic day 3.5
Specimen Label: Pre-hatch Blastocyst
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3603591
Assay Type: RT-PCR
Annotation Date: 2005-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3603610
Age: embryonic day 4.0
Specimen Label: Hatch Blastocyst
Detected: true
Specimen Num: 5
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Publication
9211743 | J:41758
First Author: Aveskogh M
Year: 1997
Journal: Immunogenetics
Title: Characterization of cDNA clones encoding mouse proteinase 3 (myeloblastine) and cathepsin G.
Volume: 46
Issue: 3
Pages: 181-91
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Publication
19494315 | J:149285
First Author: Kahn R
Year: 2009
Journal: J Immunol
Title: Neutrophil-derived proteinase 3 induces kallikrein-independent release of a novel vasoactive kinin.
Volume: 182
Issue: 12
Pages: 7906-15
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Publication
10051312 | J:53809
First Author: Belaaouaj A
Year: 1999
Journal: Mamm Genome
Title: Genomic organization and chromosomal localization of mouse proteinase 3 (Myeloblastin).
Volume: 10
Issue: 3
Pages: 210-2
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Publication
16182289 | J:102392
First Author: Wiesner O
Year: 2005
Journal: FEBS Lett
Title: Differences between human proteinase 3 and neutrophil elastase and their murine homologues are relevant for murine model experiments.
Volume: 579
Issue: 24
Pages: 5305-12
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Publication
18023421 | J:127732
First Author: Hajjar E
Year: 2007
Journal: FEBS Lett
Title: Differences in the substrate binding sites of murine and human proteinase 3 and neutrophil elastase.
Volume: 581
Issue: 29
Pages: 5685-90
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Publication
26185250 | J:225899
First Author: Warnatsch A
Year: 2015
Journal: Science
Title: Inflammation. Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis.
Volume: 349
Issue: 6245
Pages: 316-20
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Publication
25180606 | J:217636
First Author: Loison F
Year: 2014
Journal: J Clin Invest
Title: Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation.
Volume: 124
Issue: 10
Pages: 4445-58
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Publication
19833730 | J:157797
First Author: Kalupov T
Year: 2009
Journal: J Biol Chem
Title: Structural characterization of mouse neutrophil serine proteases and identification of their substrate specificities: relevance to mouse models of human inflammatory diseases.
Volume: 284
Issue: 49
Pages: 34084-91
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Publication
10037495 | J:53127
First Author: Keshet GI
Year: 1999
Journal: J Neurochem
Title: Scrapie-infected mice and PrP knockout mice share abnormal localization and activity of neuronal nitric oxide synthase.
Volume: 72
Issue: 3
Pages: 1224-31
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Publication
12189154 | J:79876
First Author: Benarafa C
Year: 2002
Journal: J Biol Chem
Title: Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1).
Volume: 277
Issue: 44
Pages: 42028-33
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Publication
8996238 | J:37575
First Author: Lützelschwab C
Year: 1997
Journal: J Exp Med
Title: Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations.
Volume: 185
Issue: 1
Pages: 13-29
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Publication
18166659 | J:131056
First Author: Sevilla LM
Year: 2007
Journal: J Cell Biol
Title: Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier.
Volume: 179
Issue: 7
Pages: 1599-612
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Publication
25331958 | J:218799
First Author: Yoon J
Year: 2014
Journal: J Biol Chem
Title: Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR.
Volume: 289
Issue: 49
Pages: 34250-7
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Publication
9611252 | J:48250
First Author: Iwama A
Year: 1998
Journal: Nucleic Acids Res
Title: Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.
Volume: 26
Issue: 12
Pages: 3034-43
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Publication
15919778 | J:100438
First Author: Chen HW
Year: 2005
Journal: Hum Reprod
Title: Transcriptome analysis in blastocyst hatching by cDNA microarray.
Volume: 20
Issue: 9
Pages: 2492-501
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Publication
- | J:72400
       
First Author: Mouse Genome Sequence and Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Mouse Genome Sequence Project Annotation
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Allele
Prtn3<em2Smoc> | MGI:7291858
Name: proteinase 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Prtn3<em1Smoc> | MGI:7291857
Name: proteinase 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Del(10Prtn3-Elane)1Deje | MGI:3803339
Name: Deletion, Chr 10, Dieter E Jenne 1
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Prtn3<tm1.1(cre/ERT2,CD4*)Wkas> | MGI:7539266
Name: proteinase 3; targeted mutation 1.1, Wolfgang Kastenmuller
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence, Recombinase
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Genotype
Genotype
Symbol: Del(10Prtn3-Elane)1Deje/Del(10Prtn3-Elane)1Deje
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prtn3/Prtn3<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Prtn3/Prtn3<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Publication
24929239 | J:213567
First Author: Guyot N
Year: 2014
Journal: Am J Pathol
Title: Unopposed cathepsin G, neutrophil elastase, and proteinase 3 cause severe lung damage and emphysema.
Volume: 184
Issue: 8
Pages: 2197-210
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Publication
25274309 | J:217490
First Author: Lukens JR
Year: 2014
Journal: Nature
Title: Dietary modulation of the microbiome affects autoinflammatory disease.
Volume: 516
Issue: 7530
Pages: 246-9
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Publication
27551156 | J:237236
First Author: Qi X
Year: 2016
Journal: J Exp Med
Title: Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection.
Volume: 213
Issue: 10
Pages: 2081-97
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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