| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry represents regulatory subunit 8 (gene name PSMC5 or Rpt6) of the 26S proteasome, which is a component of the 19S proteasome cap []. PSMC5 is one of the ATPases that form a heterohexameric ring for unfolding ubiquitinated proteins targeted for degradation by the proteasome. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
306
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schweitzer A |
| Year: |
2016 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Structure of the human 26S proteasome at a resolution of 3.9 Ã…. |
| Volume: |
113 |
| Issue: |
28 |
| Pages: |
7816-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ohnishi YH |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens. |
| Volume: |
10 |
| Issue: |
5 |
| Pages: |
e0126710 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gonzales FR |
| Year: |
2018 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Proteasome phosphorylation regulates cocaine-induced sensitization. |
| Volume: |
88 |
|
| Pages: |
62-69 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Scudder SL |
| Year: |
2021 |
| Journal: |
eNeuro |
| Title: |
Altered Phosphorylation of the Proteasome Subunit Rpt6 Has Minimal Impact on Synaptic Plasticity and Learning. |
| Volume: |
8 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Weeda G |
| Year: |
1997 |
| Journal: |
Nucleic Acids Res |
| Title: |
The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor. |
| Volume: |
25 |
| Issue: |
12 |
| Pages: |
2274-83 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2657194 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2003-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2657195 |
| Age: |
postnatal |
|
|
| Specimen Label: |
thymus |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2657194 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2003-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2657195 |
| Age: |
postnatal |
|
|
| Specimen Label: |
spleen |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2657194 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2003-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2657195 |
| Age: |
postnatal |
|
|
| Specimen Label: |
lung |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2657194 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2003-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2657195 |
| Age: |
postnatal |
|
|
| Specimen Label: |
brain |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2657194 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2003-05-13 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2657195 |
| Age: |
postnatal |
|
|
| Specimen Label: |
testis |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2657194 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2003-05-13 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2657195 |
| Age: |
postnatal |
|
|
| Specimen Label: |
ovaria |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2657194 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2003-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3557728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2657195 |
| Age: |
postnatal |
|
|
| Specimen Label: |
muscle |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2657194 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2003-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2657195 |
| Age: |
postnatal |
|
|
| Specimen Label: |
heart |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2657194 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2003-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2657195 |
| Age: |
postnatal |
|
|
| Specimen Label: |
kidney |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2657194 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2003-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2657195 |
| Age: |
postnatal |
|
|
| Specimen Label: |
liver |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2683933 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2004-01-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2683934 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2683933 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2004-01-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2683934 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2683933 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2004-01-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2683934 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2683933 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2004-01-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2683934 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2683933 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2004-01-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3557728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2683934 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2683933 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2004-01-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2683934 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2683933 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2004-01-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2683934 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2683933 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2004-01-14 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:2683934 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7510202 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-07-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7511447 |
| Age: |
postnatal week 8 |
| Image: |
2 |
|
| Specimen Label: |
Control |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7510202 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-07-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7511447 |
| Age: |
postnatal week 8 |
| Image: |
2 |
|
| Specimen Label: |
Rpn13LKO |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7510202 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-07-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7511454 |
| Age: |
postnatal week 3 |
| Image: |
4 |
|
| Specimen Label: |
Control |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7510202 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-07-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7511454 |
| Age: |
postnatal week 3 |
| Image: |
4 |
|
| Specimen Label: |
Rpn13LKO |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7510202 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-07-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7511457 |
| Age: |
postnatal |
| Image: |
5 |
|
| Specimen Label: |
Input Control |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7510202 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-07-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7511457 |
| Age: |
postnatal |
| Image: |
5 |
|
| Specimen Label: |
Input Rpn10LdeltaUIM |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7510202 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-07-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7511467 |
| Age: |
postnatal |
| Image: |
5 |
|
| Specimen Label: |
Input Control |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7510202 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-07-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7511467 |
| Age: |
postnatal |
| Image: |
5 |
|
| Specimen Label: |
Input Rpn13LKO |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7510202 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-07-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7511477 |
| Age: |
postnatal |
| Image: |
5 |
|
| Specimen Label: |
Input Control |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7510202 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-07-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7511477 |
| Age: |
postnatal |
| Image: |
5 |
|
| Specimen Label: |
Input DKO |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844415 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640515 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4848377 |
| Age: |
embryonic day 9.5 |
|
| Note: |
There is strong staining in the anterior and posterior limb. |
| Specimen Label: |
Table S4 - E9.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844415 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640517 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848377 |
| Age: |
embryonic day 10.5 |
|
| Note: |
There is strong staining in the anterior and posterior limb. |
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844415 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640519 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848377 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Staining is present in the interdigital region of the limb. |
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844415 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270515 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:4848377 |
| Age: |
embryonic day 9.5 |
|
| Note: |
Staining is present in the distal limb. |
| Specimen Label: |
Table S4 - E9.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4844415 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270519 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848377 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Staining is present in the progress zone and middle limb. |
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
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•
•
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Wellcome Trust Sanger Institute |
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2009 |
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MGI Direct Data Submission |
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Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
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Gene Ontology annotation through association of InterPro records with GO terms |
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Mouse Genome Informatics Scientific Curators |
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Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
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Mouse Gene Trap Data Load from dbGSS |
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Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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