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Search results 1 to 100 out of 3463 for Ptch1

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Type Details Score
Gene
5727 | PTCH1
Type: gene
Organism: human
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Gene
465254 | PTCH1
Type: gene
Organism: chimpanzee
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Gene
484137 | PTCH1
Type: gene
Organism: dog, domestic
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Gene
520994 | PTCH1
Type: gene
Organism: cattle
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Gene
395806 | PTCH1
Type: gene
Organism: chicken
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Gene
30189 | ptch1
Type: gene
Organism: zebrafish
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Gene
718751 | PTCH1
Type: gene
Organism: macaque, rhesus
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Gene
100492061 | ptch1
Type: gene
Organism: frog, western clawed
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Gene
89830 | Ptch1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:105373 | Ptch1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:6694891
Assay Type: RNA in situ
Annotation Date: 2021-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6694898
Age: embryonic day 11.5
Image: 3C Ptch1 E11.5
Note: Expansion of expression domain from E10.5 to E11.5.
Specimen Label: 3C Ptch1 E11.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6694891
Assay Type: RNA in situ
Annotation Date: 2021-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640615
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6694898
Age: embryonic day 9.5
Image: 3C Ptch1 E9.5
Specimen Label: 3C Ptch1 E9.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6694891
Assay Type: RNA in situ
Annotation Date: 2021-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6694898
Age: embryonic day 10.5
Image: 3C Ptch1 E10.5
Specimen Label: 3C Ptch1 E10.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7576846
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640616
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:7576874
Age: embryonic day 10.0
Image: S3C Ptch1 E10.0 delta/deltac
Note: No significant alteration in spatial distribution of expression compared to control.
Specimen Label: S3C Ptch1 E10.0 delta/deltac
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7576846
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7576874
Age: embryonic day 10.5
Image: S3C Ptch1 E10.5 WT
Specimen Label: S3C Ptch1 E10.5 WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7576846
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640616
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:7576874
Age: embryonic day 10.0
Image: S3C Ptch1 E10.0 WT
Specimen Label: S3C Ptch1 E10.0 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7576846
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7576874
Age: embryonic day 10.5
Image: S3C Ptch1 E10.5 delta/deltac
Note: No significant alteration in spatial distribution of expression compared to control.
Specimen Label: S3C Ptch1 E10.5 delta/deltac
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6436658
Assay Type: RT-PCR
Annotation Date: 2020-06-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3673015
Stage: TS15
Assay Id: MGI:6436683
Age: embryonic day 9.5
Image: 1
Specimen Label: Ptch1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5810999
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5823696
Age: embryonic day 10.5
Image: S1A - Ptch1 - E10.5
Note: This gene exhibits category 1 expression: staining is observed in the posterior/posterior-distal limb bud.
Specimen Label: S1A - Ptch1 - E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5810999
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5823696
Age: embryonic day 11.5
Image: S1A - Ptch1 - E11.5
Note: This gene exhibits category 1 expression: staining is observed in the posterior/posterior-distal limb bud.
Specimen Label: S1A - Ptch1 - E11.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-11-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7380680
Age: embryonic day 9.5
Specimen Label: S2B Ptch1
Detected: true
Specimen Num: 4
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Publication
18347096 | J:132980
First Author: Briggs KJ
Year: 2008
Journal: Genes Dev
Title: Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.
Volume: 22
Issue: 6
Pages: 770-85
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Publication
23223138 | J:197960
First Author: Kang HC
Year: 2013
Journal: J Invest Dermatol
Title: Ptch1 overexpression drives skin carcinogenesis and developmental defects in K14Ptch(FVB) mice.
Volume: 133
Issue: 5
Pages: 1311-20
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Publication
25833741 | J:222741
 
First Author: Cohen M
Year: 2015
Journal: Nat Commun
Title: Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms.
Volume: 6
Pages: 6709
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Publication
19297414 | J:147994
First Author: Moraes RC
Year: 2009
Journal: Development
Title: Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation.
Volume: 136
Issue: 9
Pages: 1423-32
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Publication
24990743 | J:213641
First Author: Lopez-Rios J
Year: 2014
Journal: Nature
Title: Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs.
Volume: 511
Issue: 7507
Pages: 46-51
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Publication
25448692 | J:218166
First Author: Zhulyn O
Year: 2015
Journal: Dev Biol
Title: Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development.
Volume: 397
Issue: 2
Pages: 191-202
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Publication
20616149 | J:163642
First Author: Ishida Y
Year: 2010
Journal: Carcinogenesis
Title: Genomic and gene expression signatures of radiation in medulloblastomas after low-dose irradiation in Ptch1 heterozygous mice.
Volume: 31
Issue: 9
Pages: 1694-701
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Publication
29079783 | J:255552
First Author: Tanno B
Year: 2017
Journal: Sci Rep
Title: Nanog-driven cell-reprogramming and self-renewal maintenance in Ptch1 +/- granule cell precursors after radiation injury.
Volume: 7
Issue: 1
Pages: 14238
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GXD Expression
GXD Expression
   
Probe: MGI:7606840
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3275717
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7606877
Age: embryonic day 10.5
Specimen Label: 4I +/+ Ptch1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7606840
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3275717
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7606877
Age: embryonic day 10.5
Note: Expression significantly increased compared to wild type.
Specimen Label: 4I -/- Ptch1
Detected: true
Specimen Num: 2
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Publication
27690174 | J:346574
First Author: Tsuruoka C
Year: 2016
Journal: Radiat Res
Title: Sensitive Detection of Radiation-Induced Medulloblastomas after Acute or Protracted Gamma-Ray Exposures in Ptch1 Heterozygous Mice Using a Radiation-Specific Molecular Signature.
Volume: 186
Issue: 4
Pages: 407-414
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Publication
30166346 | J:270265
First Author: Fleet AJ
Year: 2018
Journal: J Biol Chem
Title: The protein-specific activities of the transmembrane modules of Ptch1 and Ptch2 are determined by their adjacent protein domains.
Volume: 293
Issue: 43
Pages: 16583-16595
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GXD Expression
GXD Expression
   
Probe: MGI:6181548
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191159
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Ptch1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6181548
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191159
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Ptch1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6181548
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191159
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Ptch1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6181548
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191159
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Ptch1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6181548
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191159
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Ptch1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6181548
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191159
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Ptch1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6181548
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191159
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Ptch1
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7380680
Age: embryonic day 9.5
Note: Expression more widespread compared to bromi,Ptch1/+ embryos, but considerably weaker than Ptch1 single mutants.
Specimen Label: S2B bromi,Ptch1
Detected: true
Specimen Num: 5
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Publication
28275010 | J:240027
First Author: Monkkonen T
Year: 2017
Journal: Development
Title: Epithelial and non-epithelial Ptch1 play opposing roles to regulate proliferation and morphogenesis of the mouse mammary gland.
Volume: 144
Issue: 7
Pages: 1317-1327
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Publication
16203740 | -
First Author: Nagao K
Year: 2005
Journal: Hum Mol Genet
Title: Detecting tissue-specific alternative splicing and disease-associated aberrant splicing of the PTCH gene with exon junction microarrays.
Volume: 14
Issue: 22
Pages: 3379-88
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Protein
Q3LG17
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: true
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Publication
15576403 | J:94269
First Author: Jeong J
Year: 2005
Journal: Development
Title: Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1.
Volume: 132
Issue: 1
Pages: 143-54
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Publication
23900540 | J:199287
First Author: Holtz AM
Year: 2013
Journal: Development
Title: Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning.
Volume: 140
Issue: 16
Pages: 3423-34
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Publication
33350496 | J:332759
     
First Author: La Sala G
Year: 2020
Journal: J Neurosci Res
Title: Gpr37l1/prosaposin receptor regulates Ptch1 trafficking, Shh production, and cell proliferation in cerebellar primary astrocytes.
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Publication
31054872 | J:278143
First Author: Ferent J
Year: 2019
Journal: Neuron
Title: Boc Acts via Numb as a Shh-Dependent Endocytic Platform for Ptch1 Internalization and Shh-Mediated Axon Guidance.
Volume: 102
Issue: 6
Pages: 1157-1171.e5
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Publication
11668681 | J:72500
First Author: Izraeli S
Year: 2001
Journal: Genesis
Title: Genetic evidence that Sil is required for the Sonic Hedgehog response pathway.
Volume: 31
Issue: 2
Pages: 72-7
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Publication
31506465 | J:312496
First Author: Li C
Year: 2019
Journal: Sci Rep
Title: Patched1 haploinsufficiency severely impacts intermediary metabolism in the skin of Ptch1+/-/ODC transgenic mice.
Volume: 9
Issue: 1
Pages: 13072
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Publication
12845631 | J:84283
First Author: Kappler R
Year: 2003
Journal: J Pathol
Title: Molecular characterization of Patched-associated rhabdomyosarcoma.
Volume: 200
Issue: 3
Pages: 348-56
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Publication
17230190 | J:118622
First Author: Wakabayashi Y
Year: 2007
Journal: Nature
Title: Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice.
Volume: 445
Issue: 7129
Pages: 761-5
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Publication
21266456 | J:170123
First Author: Trazzi S
Year: 2011
Journal: Hum Mol Genet
Title: APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
Volume: 20
Issue: 8
Pages: 1560-73
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Publication
10498679 | J:56195
First Author: Milenkovic L
Year: 1999
Journal: Development
Title: Mouse patched1 controls body size determination and limb patterning.
Volume: 126
Issue: 20
Pages: 4431-40
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Publication
31482846 | J:281729
   
First Author: Deng Q
Year: 2019
Journal: Elife
Title: Activation of hedgehog signaling in mesenchymal stem cells induces cartilage and bone tumor formation via Wnt/β-Catenin.
Volume: 8
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Publication
37527037 | J:339299
First Author: Wang Q
Year: 2023
Journal: Cell Rep
Title: Hedgehog receptors exert immune-surveillance roles in the epidermis across species.
Volume: 42
Issue: 8
Pages: 112929
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Publication
18477452 | J:135169
First Author: Ohba S
Year: 2008
Journal: Dev Cell
Title: Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity.
Volume: 14
Issue: 5
Pages: 689-99
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Publication
32112900 | J:286791
 
First Author: Niesen J
Year: 2020
Journal: Cancer Lett
Title: Pik3ca mutations significantly enhance the growth of SHH medulloblastoma and lead to metastatic tumour growth in a novel mouse model.
Volume: 477
Pages: 10-18
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Publication
23897749 | J:204468
First Author: Feng W
Year: 2013
Journal: Genesis
Title: The Ptch1(DL) mouse: a new model to study lambdoid craniosynostosis and basal cell nevus syndrome-associated skeletal defects.
Volume: 51
Issue: 10
Pages: 677-89
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Publication
27626168 | J:268866
First Author: Tanno B
Year: 2016
Journal: Oncotarget
Title: Ex vivo miRNome analysis in Ptch1+/- cerebellum granule cells reveals a subset of miRNAs involved in radiation-induced medulloblastoma.
Volume: 7
Issue: 42
Pages: 68253-68269
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Publication
30833624 | J:276693
First Author: Tam A
Year: 2019
Journal: Sci Rep
Title: Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease.
Volume: 9
Issue: 1
Pages: 3353
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Publication
17287253 | J:118936
First Author: Moraes RC
Year: 2007
Journal: Development
Title: Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia.
Volume: 134
Issue: 6
Pages: 1231-42
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Publication
16273213 | J:104180
First Author: Uhmann A
Year: 2005
Journal: Int J Oncol
Title: A model for PTCH1/Ptch1-associated tumors comprising mutational inactivation and gene silencing.
Volume: 27
Issue: 6
Pages: 1567-75
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Publication
32113901 | J:317024
 
First Author: Jackson TW
Year: 2020
Journal: Neurotoxicol Teratol
Title: Heterozygous mutation of sonic hedgehog receptor (Ptch1) drives cerebellar overgrowth and sex-specifically alters hippocampal and cortical layer structure, activity, and social behavior in female mice.
Volume: 78
Pages: 106866
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Publication
15172986 | J:90301
First Author: Pazzaglia S
Year: 2004
Journal: Cancer Res
Title: Modulation of patched-associated susceptibility to radiation induced tumorigenesis by genetic background.
Volume: 64
Issue: 11
Pages: 3798-806
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Publication
14871823 | J:88072
First Author: Mancuso M
Year: 2004
Journal: Cancer Res
Title: Basal cell carcinoma and its development: insights from radiation-induced tumors in Ptch1-deficient mice.
Volume: 64
Issue: 3
Pages: 934-41
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Publication
35196485 | J:337684
First Author: Xie Y
Year: 2022
Journal: Cell Rep
Title: Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development.
Volume: 38
Issue: 8
Pages: 110416
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Publication
25263791 | J:315075
First Author: Mille F
Year: 2014
Journal: Dev Cell
Title: The Shh receptor Boc promotes progression of early medulloblastoma to advanced tumors.
Volume: 31
Issue: 1
Pages: 34-47
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Publication
26997276 | J:234877
First Author: Tamayo-Orrego L
Year: 2016
Journal: Cell Rep
Title: Evasion of Cell Senescence Leads to Medulloblastoma Progression.
Volume: 14
Issue: 12
Pages: 2925-37
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Publication
29983323 | J:269512
First Author: Furey CG
Year: 2018
Journal: Neuron
Title: De Novo Mutation in Genes Regulating Neural Stem Cell Fate in Human Congenital Hydrocephalus.
Volume: 99
Issue: 2
Pages: 302-314.e4
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Publication
19164512 | J:144617
First Author: Frappart PO
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency.
Volume: 106
Issue: 6
Pages: 1880-5
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Publication
25292199 | J:218093
First Author: Aoto K
Year: 2015
Journal: Hum Mol Genet
Title: Co-ordinated brain and craniofacial development depend upon Patched1/XIAP regulation of cell survival.
Volume: 24
Issue: 3
Pages: 698-713
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Publication
19877269 | J:154373
First Author: Town L
Year: 2009
Journal: Dev Dyn
Title: The metalloendopeptidase gene Pitrm1 is regulated by hedgehog signaling in the developing mouse limb and is expressed in muscle progenitors.
Volume: 238
Issue: 12
Pages: 3175-84
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GXD Expression
GXD Expression
 
Probe: MGI:1889613
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7380665
Age: embryonic day 9.5
Note: Broadly expressed throughout open neural tube.
Specimen Label: 2 Shh Ptch1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:1928077
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7380666
Age: embryonic day 9.5
Note: Broadly expressed throughout open neural tube.
Specimen Label: 2 FoxA2 Ptch1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:1342620
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7380668
Age: embryonic day 9.5
Note: Broadly expressed throughout open neural tube.
Specimen Label: 2 Nkx2.2 Ptch1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7380625
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616415
Stage: TS15
Assay Id: MGI:7380671
Age: embryonic day 9.5
Specimen Label: 2 Pax6 Ptch1
Detected: false
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7380628
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7380673
Age: embryonic day 9.5
Specimen Label: S2A Nkx6.1 Ptch1
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7380629
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616415
Stage: TS15
Assay Id: MGI:7380674
Age: embryonic day 9.5
Specimen Label: S2A Olig2 Ptch1
Detected: false
Specimen Num: 3
•
•
•
•
•
Publication
25834022 | J:221426
First Author: Liu J
Year: 2015
Journal: Development
Title: The loss of Hh responsiveness by a non-ciliary Gli2 variant.
Volume: 142
Issue: 9
Pages: 1651-60
•
•
•
•
•
Publication
24990742 | J:213642
First Author: Cooper KL
Year: 2014
Journal: Nature
Title: Patterning and post-patterning modes of evolutionary digit loss in mammals.
Volume: 511
Issue: 7507
Pages: 41-5
•
•
•
•
•
Publication
25842978 | J:224706
First Author: Peterson SC
Year: 2015
Journal: Cell Stem Cell
Title: Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches.
Volume: 16
Issue: 4
Pages: 400-12
•
•
•
•
•
Publication
16849540 | J:112118
First Author: Lee Y
Year: 2006
Journal: Cancer Res
Title: Patched2 modulates tumorigenesis in patched1 heterozygous mice.
Volume: 66
Issue: 14
Pages: 6964-71
•
•
•
•
•
Publication
32820036 | J:303706
First Author: Kutscher LM
Year: 2020
Journal: Genes Dev
Title: Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation.
Volume: 34
Issue: 17-18
Pages: 1161-1176
•
•
•
•
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Publication
19234491 | J:147583
First Author: Thomas WD
Year: 2009
Journal: Oncogene
Title: Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.
Volume: 28
Issue: 13
Pages: 1605-15
•
•
•
•
•
Publication
22968113 | J:188115
First Author: Chang H
Year: 2012
Journal: Dev Biol
Title: Mammary epithelial-restricted expression of activated c-src rescues the block to mammary gland morphogenesis due to the deletion of the C-terminus of Patched-1.
Volume: 370
Issue: 2
Pages: 187-97
•
•
•
•
•
Publication
28630165 | J:250545
First Author: Katic J
Year: 2017
Journal: J Cell Sci
Title: The cell adhesion molecule CHL1 interacts with patched-1 to regulate apoptosis during postnatal cerebellar development.
Volume: 130
Issue: 15
Pages: 2606-2619
•
•
•
•
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Publication
19483124 | J:151338
First Author: Siggins SL
Year: 2009
Journal: Blood
Title: The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms.
Volume: 114
Issue: 5
Pages: 995-1004
•
•
•
•
•
Publication
23404854 | J:231264
First Author: Villani RM
Year: 2013
Journal: Endocr Relat Cancer
Title: Murine basal cell carcinoma leads to tumor-mediated alterations in endocrine Igf1 signaling.
Volume: 20
Issue: 3
Pages: 273-81
•
•
•
•
•
Publication
19995795 | J:160726
First Author: Davari P
Year: 2010
Journal: Carcinogenesis
Title: Loss of Blm enhances basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Ptch1+/- mice.
Volume: 31
Issue: 6
Pages: 968-73
•
•
•
•
•
Publication
30452905 | J:272049
 
First Author: Di Pietro C
Year: 2019
Journal: Exp Neurol
Title: Genetic ablation of Gpr37l1 delays tumor occurrence in Ptch1+/- mouse models of medulloblastoma.
Volume: 312
Pages: 33-42
•
•
•
•
•
Publication
21447392 | J:177960
First Author: Gavino C
Year: 2011
Journal: Mol Cell Neurosci
Title: Patched1 haploinsufficiency impairs ependymal cilia function of the quaking viable mice, leading to fatal hydrocephalus.
Volume: 47
Issue: 2
Pages: 100-7
•
•
•
•
•
Publication
19252479 | J:147878
First Author: Gao B
Year: 2009
Journal: Nature
Title: A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range.
Volume: 458
Issue: 7242
Pages: 1196-200
•
•
•
•
•
Publication
32332736 | J:291852
First Author: Kim Y
Year: 2020
Journal: Nat Commun
Title: Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.
Volume: 11
Issue: 1
Pages: 1994
•
•
•
•
•
Publication
35472633 | J:324690
 
First Author: Wang H
Year: 2022
Journal: Matrix Biol
Title: Hedgehog signaling orchestrates cartilage-to-bone transition independently of Smoothened.
Volume: 110
Pages: 76-90
•
•
•
•
•
Publication
34752747 | J:314131
First Author: Fujii K
Year: 2021
Journal: Dev Cell
Title: Controlling tissue patterning by translational regulation of signaling transcripts through the core translation factor eIF3c.
Volume: 56
Issue: 21
Pages: 2928-2937.e9
•
•
•
•
•
Publication
25995356 | J:239367
First Author: Stasiulewicz M
Year: 2015
Journal: Development
Title: A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.
Volume: 142
Issue: 13
Pages: 2291-303
•
•
•
•
•
Publication
25458012 | J:315774
First Author: Junker JP
Year: 2014
Journal: Dev Cell
Title: A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning.
Volume: 31
Issue: 4
Pages: 448-60
•
•
•
•
•
Publication
15480423 | J:94710
First Author: Kappler R
Year: 2004
Journal: Oncogene
Title: Profiling the molecular difference between Patched- and p53-dependent rhabdomyosarcoma.
Volume: 23
Issue: 54
Pages: 8785-95
•
•
•
•
•
Publication
30487124 | J:320766
First Author: Rodriguez-Blanco J
Year: 2019
Journal: Clin Cancer Res
Title: A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma.
Volume: 25
Issue: 4
Pages: 1379-1388
•
•
•
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•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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