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Search results 1 to 100 out of 4330 for Pten

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Hits by Category

Type Details Score
Gene
5728 | PTEN
Type: gene
Organism: human
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Gene
540786 | PTEN
Type: gene
Organism: cattle
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Gene
423675 | PTEN
Type: gene
Organism: chicken
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Gene
705121 | PTEN
Type: gene
Organism: macaque, rhesus
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Gene
100144716 | pten
Type: gene
Organism: frog, western clawed
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Gene
50557 | Pten
Type: gene
Organism: rat
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Gene
403832 | PTEN
Type: gene
Organism: dog, domestic
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Gene
466142 | PTEN
Type: gene
Organism: chimpanzee
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Protein
A0A6G7SEK5
Organism: Mus musculus/domesticus
Length: 403  
Fragment?: true
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Protein
A0A6G7SF19
Organism: Mus musculus/domesticus
Length: 403  
Fragment?: true
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Protein Coding Gene
MGI:109583 | Pten
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:7341820
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160398
Stage: TS08
Assay Id: MGI:7343549
Age: embryonic day 5.5
Image: 1A Pten (-)
Specimen Label: 1A Pten (-)
Detected: false
Specimen Num: 2
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Gene
65018 | PINK1
Type: gene
Organism: human
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Protein
A0A1V0DNR6
Organism: Mus musculus/domesticus
Length: 549  
Fragment?: false
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Protein
A0A024QYR9
Organism: Mus musculus/domesticus
Length: 572  
Fragment?: false
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GXD Expression
GXD Expression
 
Probe: MGI:3584409
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1657821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6363485
Age: embryonic day 13.5
Image: 3B Pten KO
Specimen Label: 3B Pten KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6363456
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1657821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6363496
Age: embryonic day 13.5
Image: 3B beta-catenin Pten KO
Note: Expression localized in plasma membrane and cytoplasm, not in the nucleus.
Specimen Label: 3B beta-catenin Pten KO
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:3617793
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:7343555
Age: embryonic day 5.5
Image: 1A Pten (-)
Note: Expression in this mutant is the same as in wild-type.
Specimen Label: 1A Pten (-)
Detected: true
Specimen Num: 2
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Publication
20940307 | J:178436
First Author: Xu D
Year: 2010
Journal: J Biol Chem
Title: Regulation of PTEN stability and activity by Plk3.
Volume: 285
Issue: 51
Pages: 39935-42
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Publication
10339565 | J:71874
First Author: Sun H
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway.
Volume: 96
Issue: 11
Pages: 6199-204
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Publication
26399523 | J:227225
 
First Author: Shnitsar I
Year: 2015
Journal: Nat Commun
Title: PTEN regulates cilia through Dishevelled.
Volume: 6
Pages: 8388
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Publication
20554973 | J:165893
First Author: Weng Z
Year: 2010
Journal: Blood
Title: PTEN regulates collagen-induced platelet activation.
Volume: 116
Issue: 14
Pages: 2579-81
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Publication
20008297 | J:157776
First Author: Vemula S
Year: 2010
Journal: Blood
Title: ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability.
Volume: 115
Issue: 9
Pages: 1785-96
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Publication
21524277 | J:329567
First Author: Huang Y
Year: 2011
Journal: Cell Biol Int
Title: Dispensable role of PTEN in mouse spermatogenesis.
Volume: 35
Issue: 9
Pages: 905-8
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Publication
19473982 | J:153190
First Author: Van Themsche C
Year: 2009
Journal: J Biol Chem
Title: X-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalization.
Volume: 284
Issue: 31
Pages: 20462-6
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Publication
20807812 | J:164210
First Author: Hill R
Year: 2010
Journal: Cancer Res
Title: PTEN loss accelerates KrasG12D-induced pancreatic cancer development.
Volume: 70
Issue: 18
Pages: 7114-24
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GXD Expression
GXD Expression
   
Probe: MGI:666662
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354755
Age: embryonic day 14.5
Specimen Label: Table S5 - Pten
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:666662
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354755
Age: embryonic day 14.5
Note: Expression is present in the upper and lower cortical plate.
Specimen Label: Table S5 - Pten
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:666662
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354755
Age: embryonic day 14.5
Specimen Label: Table S5 - Pten
Detected: true
Specimen Num: 1
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Publication
17921358 | J:146355
First Author: Davé V
Year: 2008
Journal: Am J Respir Cell Mol Biol
Title: Conditional deletion of Pten causes bronchiolar hyperplasia.
Volume: 38
Issue: 3
Pages: 337-45
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Publication
26076167 | J:233809
First Author: Lokody IB
Year: 2015
Journal: PLoS One
Title: Pten Regulates Epithelial Cytodifferentiation during Prostate Development.
Volume: 10
Issue: 6
Pages: e0129470
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Publication
16598206 | J:109085
First Author: Yilmaz OH
Year: 2006
Journal: Nature
Title: Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells.
Volume: 441
Issue: 7092
Pages: 475-82
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Publication
26477312 | J:226088
First Author: Manda KR
Year: 2016
Journal: Oncogene
Title: NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence.
Volume: 35
Issue: 25
Pages: 3282-92
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Publication
22405073 | J:182671
First Author: Ortega-Molina A
Year: 2012
Journal: Cell Metab
Title: Pten positively regulates brown adipose function, energy expenditure, and longevity.
Volume: 15
Issue: 3
Pages: 382-94
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Publication
21771908 | J:174190
First Author: Ming M
Year: 2011
Journal: Cancer Res
Title: PTEN positively regulates UVB-induced DNA damage repair.
Volume: 71
Issue: 15
Pages: 5287-95
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Publication
32673396 | J:313432
 
First Author: Qi Y
Year: 2020
Journal: J Cell Biol
Title: PTEN dephosphorylates Abi1 to promote epithelial morphogenesis.
Volume: 219
Issue: 9
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Publication
22401813 | J:186096
First Author: Garcia-Cao I
Year: 2012
Journal: Cell
Title: Systemic elevation of PTEN induces a tumor-suppressive metabolic state.
Volume: 149
Issue: 1
Pages: 49-62
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Publication
16489020 | J:106650
First Author: Zhong C
Year: 2006
Journal: Cancer Res
Title: Cooperation between FGF8b overexpression and PTEN deficiency in prostate tumorigenesis.
Volume: 66
Issue: 4
Pages: 2188-94
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Publication
25641678 | J:220713
First Author: Lin J
Year: 2015
Journal: J Pathol
Title: Loss of PTEN promotes podocyte cytoskeletal rearrangement, aggravating diabetic nephropathy.
Volume: 236
Issue: 1
Pages: 30-40
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Publication
19211894 | J:146630
First Author: Gregorian C
Year: 2009
Journal: J Neurosci
Title: Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.
Volume: 29
Issue: 6
Pages: 1874-86
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Publication
19261747 | J:146760
First Author: Puzio-Kuter AM
Year: 2009
Journal: Genes Dev
Title: Inactivation of p53 and Pten promotes invasive bladder cancer.
Volume: 23
Issue: 6
Pages: 675-80
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Publication
26460096 | J:228517
First Author: Xing Y
Year: 2015
Journal: Dev Biol
Title: PTEN regulates lung endodermal morphogenesis through MEK/ERK pathway.
Volume: 408
Issue: 1
Pages: 56-65
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Publication
24582960 | J:211713
First Author: Hertzler-Schaefer K
Year: 2014
Journal: Cell Rep
Title: Pten loss induces autocrine FGF signaling to promote skin tumorigenesis.
Volume: 6
Issue: 5
Pages: 818-26
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Publication
28323888 | J:247150
First Author: Yu EJ
Year: 2017
Journal: PLoS One
Title: LZTS2 and PTEN collaboratively regulate ß-catenin in prostatic tumorigenesis.
Volume: 12
Issue: 3
Pages: e0174357
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Publication
21654839 | J:182199
First Author: Parapuram SK
Year: 2011
Journal: J Invest Dermatol
Title: Loss of PTEN expression by dermal fibroblasts causes skin fibrosis.
Volume: 131
Issue: 10
Pages: 1996-2003
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Publication
19470765 | J:149666
First Author: Guha M
Year: 2009
Journal: Cancer Res
Title: Endogenous tumor suppression mediated by PTEN involves survivin gene silencing.
Volume: 69
Issue: 12
Pages: 4954-8
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Publication
29018045 | J:251492
First Author: Kim HS
Year: 2017
Journal: J Exp Med
Title: PTEN drives Th17 cell differentiation by preventing IL-2 production.
Volume: 214
Issue: 11
Pages: 3381-3398
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Publication
19038262 | J:149180
First Author: Ruan H
Year: 2009
Journal: J Mol Cell Cardiol
Title: Inducible and cardiac specific PTEN inactivation protects ischemia/reperfusion injury.
Volume: 46
Issue: 2
Pages: 193-200
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Publication
30814515 | J:293994
First Author: Huang H
Year: 2019
Journal: Cell Death Dis
Title: AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration.
Volume: 10
Issue: 3
Pages: 203
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Publication
24482365 | J:209151
First Author: Cui M
Year: 2014
Journal: Mol Cancer Res
Title: PTEN is a potent suppressor of small cell lung cancer.
Volume: 12
Issue: 5
Pages: 654-9
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Publication
37225693 | J:335810
First Author: van Ree JH
Year: 2023
Journal: Nat Commun
Title: Hyperphosphorylated PTEN exerts oncogenic properties.
Volume: 14
Issue: 1
Pages: 2983
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GO Term
GO:1990455 | PTEN phosphatase complex
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Publication
25646418 | J:220011
First Author: Leong JW
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: PTEN regulates natural killer cell trafficking in vivo.
Volume: 112
Issue: 7
Pages: E700-9
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Publication
33214645 | J:300231
First Author: de Mello NP
Year: 2020
Journal: Sci Rep
Title: Inverse sex-based expression profiles of PTEN and Klotho in mice.
Volume: 10
Issue: 1
Pages: 20189
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Publication
18451155 | J:134611
First Author: Kwon CH
Year: 2008
Journal: Cancer Res
Title: Pten haploinsufficiency accelerates formation of high-grade astrocytomas.
Volume: 68
Issue: 9
Pages: 3286-94
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Publication
29056325 | J:251968
First Author: Malek M
Year: 2017
Journal: Mol Cell
Title: PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.
Volume: 68
Issue: 3
Pages: 566-580.e10
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Publication
20694004 | J:165283
First Author: Liu K
Year: 2010
Journal: Nat Neurosci
Title: PTEN deletion enhances the regenerative ability of adult corticospinal neurons.
Volume: 13
Issue: 9
Pages: 1075-81
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Publication
22900024 | J:189934
First Author: Napoli E
Year: 2012
Journal: PLoS One
Title: Mitochondrial dysfunction in Pten haplo-insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53.
Volume: 7
Issue: 8
Pages: e42504
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Publication
21836055 | J:178019
First Author: Byun DS
Year: 2011
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Intestinal epithelial-specific PTEN inactivation results in tumor formation.
Volume: 301
Issue: 5
Pages: G856-64
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Publication
19846776 | J:154673
First Author: Gregorian C
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: PTEN dosage is essential for neurofibroma development and malignant transformation.
Volume: 106
Issue: 46
Pages: 19479-84
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Publication
12563260 | J:83213
First Author: Anzelon AN
Year: 2003
Journal: Nat Immunol
Title: Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function.
Volume: 4
Issue: 3
Pages: 287-94
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Publication
32728066 | J:308615
First Author: Qi Y
Year: 2020
Journal: Sci Rep
Title: PTEN suppresses epithelial-mesenchymal transition and cancer stem cell activity by downregulating Abi1.
Volume: 10
Issue: 1
Pages: 12685
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Publication
14691534 | J:86212
First Author: Trotman LC
Year: 2003
Journal: PLoS Biol
Title: Pten dose dictates cancer progression in the prostate.
Volume: 1
Issue: 3
Pages: E59
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Publication
18928559 | J:241768
 
First Author: Ohtoshi A
Year: 2008
Journal: Cerebrospinal Fluid Res
Title: Hydrocephalus caused by conditional ablation of the Pten or beta-catenin gene.
Volume: 5
Pages: 16
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Publication
19057511 | J:144234
First Author: Yu J
Year: 2009
Journal: EMBO J
Title: PTEN regulation by Akt-EGR1-ARF-PTEN axis.
Volume: 28
Issue: 1
Pages: 21-33
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Publication
20200318 | J:169364
First Author: Hu Z
Year: 2010
Journal: Diabetes
Title: PTEN inhibition improves muscle regeneration in mice fed a high-fat diet.
Volume: 59
Issue: 6
Pages: 1312-20
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Publication
36171333 | J:329202
First Author: Arai N
Year: 2022
Journal: Sci Rep
Title: Probiotics suppress nonalcoholic steatohepatitis and carcinogenesis progression in hepatocyte-specific PTEN knockout mice.
Volume: 12
Issue: 1
Pages: 16206
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Publication
16633340 | J:109084
First Author: Zhang J
Year: 2006
Journal: Nature
Title: PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention.
Volume: 441
Issue: 7092
Pages: 518-22
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Publication
25609613 | J:218890
First Author: Williams MR
Year: 2015
Journal: J Neurosci
Title: Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive.
Volume: 35
Issue: 3
Pages: 943-59
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Publication
22209699 | J:181962
First Author: Conley-LaComb MK
Year: 2012
Journal: Am J Pathol
Title: PTEN regulates PDGF ligand switch for β-PDGFR signaling in prostate cancer.
Volume: 180
Issue: 3
Pages: 1017-27
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Publication
24632614 | J:219257
First Author: Miyagawa S
Year: 2015
Journal: Oncogene
Title: Unique roles of estrogen-dependent Pten control in epithelial cell homeostasis of mouse vagina.
Volume: 34
Issue: 8
Pages: 1035-43
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Publication
18239123 | J:131827
First Author: Reddy P
Year: 2008
Journal: Science
Title: Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool.
Volume: 319
Issue: 5863
Pages: 611-3
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Publication
26307673 | J:224977
 
First Author: Conde-Perez A
Year: 2015
Journal: Nat Commun
Title: A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity.
Volume: 6
Pages: 8093
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Publication
26692175 | J:260236
First Author: Li S
Year: 2016
Journal: Nat Immunol
Title: The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Volume: 17
Issue: 3
Pages: 241-9
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Publication
36339257 | J:330731
First Author: Geoffroy CG
Year: 2022
Journal: iScience
Title: Targeting PTEN but not SOCS3 resists an age-dependent decline in promoting axon sprouting.
Volume: 25
Issue: 11
Pages: 105383
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Publication
16488991 | J:106662
First Author: Yoo LI
Year: 2006
Journal: Cancer Res
Title: Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner.
Volume: 66
Issue: 4
Pages: 1929-39
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Publication
14522255 | J:93902
First Author: Wang S
Year: 2003
Journal: Cancer Cell
Title: Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer.
Volume: 4
Issue: 3
Pages: 209-21
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Publication
16432235 | J:105995
First Author: Wang S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation.
Volume: 103
Issue: 5
Pages: 1480-5
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Publication
11691952 | J:73255
First Author: Groszer M
Year: 2001
Journal: Science
Title: Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.
Volume: 294
Issue: 5549
Pages: 2186-9
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Publication
19454716 | J:148853
First Author: Sarraj B
Year: 2009
Journal: J Immunol
Title: Myeloid-specific deletion of tumor suppressor PTEN augments neutrophil transendothelial migration during inflammation.
Volume: 182
Issue: 11
Pages: 7190-200
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Publication
17202315 | J:145331
First Author: Subramanian KK
Year: 2007
Journal: Blood
Title: Tumor suppressor PTEN is a physiologic suppressor of chemoattractant-mediated neutrophil functions.
Volume: 109
Issue: 9
Pages: 4028-37
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Publication
33771972 | J:319431
First Author: Wang XQ
Year: 2021
Journal: Transl Psychiatry
Title: PTEN in prefrontal cortex is essential in regulating depression-like behaviors in mice.
Volume: 11
Issue: 1
Pages: 185
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Publication
25829446 | J:260282
First Author: Mense SM
Year: 2015
Journal: Sci Signal
Title: PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion.
Volume: 8
Issue: 370
Pages: ra32
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Publication
24561254 | J:211716
First Author: Sun Z
Year: 2014
Journal: Cell Rep
Title: PTEN C-terminal deletion causes genomic instability and tumor development.
Volume: 6
Issue: 5
Pages: 844-54
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Publication
22056987 | J:179396
First Author: Sun F
Year: 2011
Journal: Nature
Title: Sustained axon regeneration induced by co-deletion of PTEN and SOCS3.
Volume: 480
Issue: 7377
Pages: 372-5
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Publication
26992888 | J:259025
 
First Author: Getz SA
Year: 2016
Journal: Neurobiol Dis
Title: Rapamycin prevents, but does not reverse, aberrant migration in Pten knockout neurons.
Volume: 93
Pages: 12-20
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Publication
35394871 | J:336695
First Author: Sathyanarayana SH
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Pten heterozygosity restores neuronal morphology in fragile X syndrome mice.
Volume: 119
Issue: 15
Pages: e2109448119
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Publication
26233892 | J:316240
First Author: Sun X
Year: 2015
Journal: J Genet Genomics
Title: Additive Effect of Zfhx3/Atbf1 and Pten Deletion on Mouse Prostatic Tumorigenesis.
Volume: 42
Issue: 7
Pages: 373-82
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Publication
26914657 | J:249209
First Author: Garfin PM
Year: 2016
Journal: PLoS One
Title: Loss of Pten Disrupts the Thymic Epithelium and Alters Thymic Function.
Volume: 11
Issue: 2
Pages: e0149430
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Publication
24127490 | J:206536
First Author: Tesio M
Year: 2013
Journal: J Exp Med
Title: Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization.
Volume: 210
Issue: 11
Pages: 2337-49
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Publication
26974310 | J:234820
First Author: Shojaee S
Year: 2016
Journal: Nat Med
Title: PTEN opposes negative selection and enables oncogenic transformation of pre-B cells.
Volume: 22
Issue: 4
Pages: 379-87
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Publication
27597527 | J:259321
 
First Author: LaSarge CL
Year: 2016
Journal: Neurobiol Dis
Title: Disrupted hippocampal network physiology following PTEN deletion from newborn dentate granule cells.
Volume: 96
Pages: 105-114
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Publication
14769918 | J:88441
First Author: Stiles B
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected].
Volume: 101
Issue: 7
Pages: 2082-7
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Publication
31512783 | J:306130
First Author: Fan X
Year: 2019
Journal: Mol Carcinog
Title: A basal-enriched microRNA is required for prostate tumorigenesis in a Pten knockout mouse model.
Volume: 58
Issue: 12
Pages: 2241-2253
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Publication
28137614 | J:249259
 
First Author: Lan ZJ
Year: 2017
Journal: Mol Cell Endocrinol
Title: Selective deletion of Pten in theca-interstitial cells leads to androgen excess and ovarian dysfunction in mice.
Volume: 444
Pages: 26-37
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Publication
24875179 | J:213269
 
First Author: Li W
Year: 2014
Journal: Neuroscience
Title: PTEN degradation after ischemic stroke: a double-edged sword.
Volume: 274
Pages: 153-61
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Publication
37084991 | J:335597
 
First Author: Pearson A
Year: 2023
Journal: Mol Cell Neurosci
Title: Deletion of PTEN in microglia ameliorates chronic neuroinflammation following repetitive mTBI.
Volume: 125
Pages: 103855
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Publication
28855130 | J:258149
 
First Author: Santos VR
Year: 2017
Journal: Neurobiol Dis
Title: PTEN deletion increases hippocampal granule cell excitability in male and female mice.
Volume: 108
Pages: 339-351
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Publication
25377472 | J:218222
First Author: Kim TH
Year: 2014
Journal: Cancer Res
Title: Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation.
Volume: 74
Issue: 24
Pages: 7371-82
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Publication
20956547 | J:166155
First Author: Miletic AV
Year: 2010
Journal: J Exp Med
Title: Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases.
Volume: 207
Issue: 11
Pages: 2407-20
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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