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Search results 1 to 100 out of 1104 for Ptn

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:3696054
Assay Type: RNA in situ
Annotation Date: 2007-02-08
Strength: Present
Sex: Male
Emaps: EMAPS:2909821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3696055
Age: embryonic day 13.5
Image: 4 Ptn XY
Specimen Label: 4 Ptn XY
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7423850
Assay Type: RNA in situ
Annotation Date: 2023-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1779724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7424906
Age: embryonic day 16.5
Image: 2 - Ptn
Note: The mucosal OECs show expression.
Specimen Label: 2 - Ptn
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3696054
Assay Type: RNA in situ
Annotation Date: 2007-02-08
Strength: Absent
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:3696055
Age: embryonic day 13.5
Image: 4 Ptn XX
Specimen Label: 4 Ptn XX
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:7423850
Assay Type: RNA in situ
Annotation Date: 2023-01-10
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760624
Pattern: Scattered
Stage: TS24
Assay Id: MGI:7424906
Age: embryonic day 16.5
Image: 2 - Ptn
Specimen Label: 2 - Ptn
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7423850
Assay Type: RNA in situ
Annotation Date: 2023-01-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757624
Stage: TS24
Assay Id: MGI:7424906
Age: embryonic day 16.5
Image: 2 - Ptn
Note: The Schwann cells lack expression.
Specimen Label: 2 - Ptn
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:7423850
Assay Type: RNA in situ
Annotation Date: 2023-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561424
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:7424906
Age: embryonic day 16.5
Image: 2 - Ptn
Note: The inner ONL-OECs show stronger expression than the outer ones.
Specimen Label: 2 - Ptn
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7423850
Assay Type: RNA in situ
Annotation Date: 2023-01-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1609824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7424906
Age: embryonic day 16.5
Image: 2 - Ptn
Note: Expression is seen in a thin layer of mesenchyme surrounding the ONL and olfactory nerve fascicles and in mesenchyme surrounding trigeminal nerve fascicles.
Specimen Label: 2 - Ptn
Detected: true
Specimen Num: 1
Publication
First Author: Hornum L
Year: 1996
Journal: Mamm Genome
Title: Mapping of the rat Ptn gene to chromosome 4.
Volume: 7
Issue: 12
Pages: 923-4
Publication
First Author: O'Hara B
Year: 1995
Journal: Cytogenet Cell Genet
Title: Chromosomal assignment of the heparin-binding cytokine genes MDK and PTN in mouse and man.
Volume: 69
Issue: 1-2
Pages: 40-3
Publication
First Author: Huang JF
Year: 2019
Journal: Oncogene
Title: Genome-wide screening identifies oncofetal lncRNA Ptn-dt promoting the proliferation of hepatocellular carcinoma cells by regulating the Ptn receptor.
Volume: 38
Issue: 18
Pages: 3428-3445
Publication
First Author: Yu HF
Year: 2018
Journal: J Cell Physiol
Title: Ptn functions downstream of C/EBPβ to mediate the effects of cAMP on uterine stromal cell differentiation through targeting Hand2 in response to progesterone.
Volume: 233
Issue: 2
Pages: 1612-1626
Publication
First Author: Tare RS
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Effects of targeted overexpression of pleiotrophin on postnatal bone development.
Volume: 298
Issue: 3
Pages: 324-32
Publication
First Author: Tavella S
Year: 2012
Journal: PLoS One
Title: Bone turnover in wild type and pleiotrophin-transgenic mice housed for three months in the International Space Station (ISS).
Volume: 7
Issue: 3
Pages: e33179
Publication
First Author: Camerino GM
Year: 2013
Journal: PLoS One
Title: Effects of pleiotrophin overexpression on mouse skeletal muscles in normal loading and in actual and simulated microgravity.
Volume: 8
Issue: 8
Pages: e72028
Publication
First Author: Masuda H
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Bone mass loss due to estrogen deficiency is compensated in transgenic mice overexpressing human osteoblast stimulating factor-1.
Volume: 238
Issue: 2
Pages: 528-33
Publication
First Author: McCarville JL
Year: 2013
Journal: PLoS One
Title: Spaceflight influences both mucosal and peripheral cytokine production in PTN-Tg and wild type mice.
Volume: 8
Issue: 7
Pages: e68961
Publication
First Author: Himburg HA
Year: 2012
Journal: Cell Rep
Title: Pleiotrophin regulates the retention and self-renewal of hematopoietic stem cells in the bone marrow vascular niche.
Volume: 2
Issue: 4
Pages: 964-75
Publication
First Author: Himburg HA
Year: 2020
Journal: J Clin Invest
Title: Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling.
Volume: 130
Issue: 1
Pages: 315-328
Publication
First Author: Pavlov I
Year: 2002
Journal: Mol Cell Neurosci
Title: Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice.
Volume: 20
Issue: 2
Pages: 330-42
Publication
First Author: Gu D
Year: 2007
Journal: FEBS Lett
Title: The effect of pleiotrophin signaling on adipogenesis.
Volume: 581
Issue: 3
Pages: 382-8
Publication
First Author: Yi C
Year: 2011
Journal: FEBS Lett
Title: MiR-143 enhances adipogenic differentiation of 3T3-L1 cells through targeting the coding region of mouse pleiotrophin.
Volume: 585
Issue: 20
Pages: 3303-9
Publication
First Author: Li H
Year: 2023
Journal: Cell Rep
Title: Pleiotrophin ameliorates age-induced adult hippocampal neurogenesis decline and cognitive dysfunction.
Volume: 42
Issue: 9
Pages: 113022
Publication  
First Author: Ganguly D
Year: 2023
Journal: J Exp Med
Title: Pleiotrophin drives a prometastatic immune niche in breast cancer.
Volume: 220
Issue: 5
Publication
First Author: Ezquerra L
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Pleiotrophin is a major regulator of the catecholamine biosynthesis pathway in mouse aorta.
Volume: 323
Issue: 2
Pages: 512-7
Publication
First Author: Li YS
Year: 1990
Journal: Science
Title: Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity.
Volume: 250
Issue: 4988
Pages: 1690-4
Publication
First Author: Li YS
Year: 1992
Journal: Biochem Biophys Res Commun
Title: Pleiotrophin gene expression is highly restricted and is regulated by platelet-derived growth factor.
Volume: 184
Issue: 1
Pages: 427-32
Publication
First Author: Zhang N
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: A dominant-negative pleiotrophin mutant introduced by homologous recombination leads to germ-cell apoptosis in male mice.
Volume: 96
Issue: 12
Pages: 6734-8
Publication
First Author: Yanagisawa H
Year: 2010
Journal: Neurosci Res
Title: Pleiotrophin induces neurite outgrowth and up-regulates growth-associated protein (GAP)-43 mRNA through the ALK/GSK3beta/beta-catenin signaling in developing mouse neurons.
Volume: 66
Issue: 1
Pages: 111-6
Publication
First Author: Himburg HA
Year: 2018
Journal: Cell Stem Cell
Title: Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration.
Volume: 23
Issue: 3
Pages: 370-381.e5
Publication
First Author: Zhang L
Year: 2016
Journal: Oncotarget
Title: Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells.
Volume: 7
Issue: 49
Pages: 80382-80390
Publication
First Author: Istvanffy R
Year: 2011
Journal: Blood
Title: Stromal pleiotrophin regulates repopulation behavior of hematopoietic stem cells.
Volume: 118
Issue: 10
Pages: 2712-22
Publication
First Author: Krellman JW
Year: 2014
Journal: PLoS One
Title: Behavioral and neuroanatomical abnormalities in pleiotrophin knockout mice.
Volume: 9
Issue: 7
Pages: e100597
Publication  
First Author: González-Castillo C
Year: 2016
Journal: Mol Cell Neurosci
Title: The absence of pleiotrophin modulates gene expression in the hippocampus in vivo and in cerebellar granule cells in vitro.
Volume: 75
Pages: 113-21
Publication
First Author: Lehmann W
Year: 2004
Journal: Bone
Title: Absence of mouse pleiotrophin does not affect bone formation in vivo.
Volume: 35
Issue: 6
Pages: 1247-55
Publication
First Author: Vicente-Rodríguez M
Year: 2014
Journal: J Neurochem
Title: Pleiotrophin differentially regulates the rewarding and sedative effects of ethanol.
Volume: 131
Issue: 5
Pages: 688-95
Publication  
First Author: Kesavan C
Year: 2008
Journal: BMC Res Notes
Title: Lack of anabolic response to skeletal loading in mice with targeted disruption of the pleiotrophin gene.
Volume: 1
Pages: 124
Publication
First Author: Gramage E
Year: 2010
Journal: Neuroscience
Title: Genetic inactivation of pleiotrophin triggers amphetamine-induced cell loss in the substantia nigra and enhances amphetamine neurotoxicity in the striatum.
Volume: 170
Issue: 1
Pages: 308-16
Publication
First Author: Fernández-Calle R
Year: 2020
Journal: Sci Rep
Title: Role of RPTPβ/ζ in neuroinflammation and microglia-neuron communication.
Volume: 10
Issue: 1
Pages: 20259
Publication
First Author: Gramage E
Year: 2022
Journal: Sci Rep
Title: Metabolomics and biochemical alterations caused by pleiotrophin in the 6-hydroxydopamine mouse model of Parkinson's disease.
Volume: 12
Issue: 1
Pages: 3577
Publication
First Author: Li YS
Year: 1992
Journal: J Biol Chem
Title: Characterization of the human pleiotrophin gene. Promoter region and chromosomal localization.
Volume: 267
Issue: 36
Pages: 26011-6
Publication
First Author: Obama H
Year: 1995
Journal: J Biochem
Title: Midkine (MK) expression in extraembryonic tissues, amniotic fluid, and cerebrospinal fluid during mouse embryogenesis.
Volume: 118
Issue: 1
Pages: 88-93
Publication  
First Author: Gramage E
Year: 2015
Journal: Neurosci Lett
Title: Pleiotrophin modulates morphine withdrawal but has no effects on morphine-conditioned place preference.
Volume: 604
Pages: 75-9
Publication
First Author: Sevillano J
Year: 2019
Journal: Diabetologia
Title: Pleiotrophin deletion alters glucose homeostasis, energy metabolism and brown fat thermogenic function in mice.
Volume: 62
Issue: 1
Pages: 123-135
Publication
First Author: Bao X
Year: 2005
Journal: J Biol Chem
Title: Heparin-binding growth factor, pleiotrophin, mediates neuritogenic activity of embryonic pig brain-derived chondroitin sulfate/dermatan sulfate hybrid chains.
Volume: 280
Issue: 10
Pages: 9180-91
Publication
First Author: Fernández-Calle R
Year: 2017
Journal: J Neuroinflammation
Title: Pleiotrophin regulates microglia-mediated neuroinflammation.
Volume: 14
Issue: 1
Pages: 46
Publication
First Author: Ochiai K
Year: 2004
Journal: Liver Int
Title: The role of midkine and pleiotrophin in liver regeneration.
Volume: 24
Issue: 5
Pages: 484-91
Publication  
First Author: Gramage E
Year: 2013
Journal: Behav Brain Res
Title: Regulation of extinction of cocaine-induced place preference by midkine is related to a differential phosphorylation of peroxiredoxin 6 in dorsal striatum.
Volume: 253
Pages: 223-31
Publication  
First Author: Vicente-Rodríguez M
Year: 2021
Journal: Neurosci Lett
Title: Genetic inactivation of midkine, not pleiotrophin, facilitates extinction of alcohol-induced conditioned place preference.
Volume: 762
Pages: 136156
Publication  
First Author: Vicente-Rodríguez M
Year: 2013
Journal: Pharmacol Biochem Behav
Title: Genetic inactivation of pleiotrophin but not midkine potentiates clonidine-induced alpha-2 adrenergic-mediated analgesia.
Volume: 110
Pages: 185-91
Publication  
First Author: Fernández-Calle R
Year: 2018
Journal: Neurosci Lett
Title: Endogenous pleiotrophin and midkine regulate LPS-induced glial responses.
Volume: 662
Pages: 213-218
Publication
First Author: Ezquerra L
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Midkine, a newly discovered regulator of the renin-angiotensin pathway in mouse aorta: significance of the pleiotrophin/midkine developmental gene family in angiotensin II signaling.
Volume: 333
Issue: 2
Pages: 636-43
Publication
First Author: Herradon G
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Midkine regulates pleiotrophin organ-specific gene expression: evidence for transcriptional regulation and functional redundancy within the pleiotrophin/midkine developmental gene family.
Volume: 333
Issue: 3
Pages: 714-21
Publication
First Author: Himburg HA
Year: 2014
Journal: J Clin Invest
Title: Pleiotrophin mediates hematopoietic regeneration via activation of RAS.
Volume: 124
Issue: 11
Pages: 4753-8
Publication  
First Author: Cui R
Year: 2019
Journal: Gene Expr Patterns
Title: Expression of the heparin-binding growth factors Midkine and pleiotrophin during ocular development.
Volume: 32
Pages: 28-37
GXD Expression  
Probe: MGI:3784198
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7425190
Age: embryonic day 16.5
Note: Expression is seen in mature olfactory receptor neurons.
Specimen Label: Ptn +/+
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3784198
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7425190
Age: embryonic day 16.5
Note: Expression is seen in mature olfactory receptor neurons. There is no significant difference in their number in the heterozygote compared to wild type.
Specimen Label: Ptn +/-
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3784198
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7425190
Age: embryonic day 16.5
Note: Expression is seen in mature olfactory receptor neurons. There is no significant difference in their number in the null compared to wild type.
Specimen Label: Ptn -/-
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7423908
Assay Type: RNA in situ
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689524
Pattern: Single cells
Stage: TS24
Assay Id: MGI:7425191
Age: embryonic day 16.5
Specimen Label: Ptn +/+
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7423908
Assay Type: RNA in situ
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689524
Pattern: Single cells
Stage: TS24
Assay Id: MGI:7425191
Age: embryonic day 16.5
Note: There is no significant difference in the number of GnRH neurons inside the forebrain of the heterozygote compared to wild type.
Specimen Label: Ptn +/-
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:7423908
Assay Type: RNA in situ
Annotation Date: 2023-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689524
Pattern: Single cells
Stage: TS24
Assay Id: MGI:7425191
Age: embryonic day 16.5
Note: There is no significant difference in the number of GnRH neurons inside the forebrain of the null compared to wild type.
Specimen Label: Ptn -/-
Detected: true
Specimen Num: 6
Publication
First Author: Gramage E
Year: 2012
Journal: Pharmacol Biochem Behav
Title: The heparin binding growth factors midkine and pleiotrophin regulate the antinociceptive effects of morphine through α(2)-adrenergic independent mechanisms.
Volume: 101
Issue: 3
Pages: 387-93
Publication
First Author: Kuboyama K
Year: 2016
Journal: J Biol Chem
Title: Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION.
Volume: 291
Issue: 35
Pages: 18117-28
Publication
First Author: Herradon G
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Pleiotrophin is an important regulator of the renin-angiotensin system in mouse aorta.
Volume: 324
Issue: 3
Pages: 1041-7
Publication
First Author: Erlandsen H
Year: 2012
Journal: J Histochem Cytochem
Title: Pleiotrophin expression during odontogenesis.
Volume: 60
Issue: 5
Pages: 366-75
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Tezuka K
Year: 1990
Journal: Biochem Biophys Res Commun
Title: Isolation of mouse and human cDNA clones encoding a protein expressed specifically in osteoblasts and brain tissues.
Volume: 173
Issue: 1
Pages: 246-51
Publication
First Author: Katoh K
Year: 1992
Journal: DNA Cell Biol
Title: Genomic organization of the mouse OSF-1 gene.
Volume: 11
Issue: 10
Pages: 735-43
Publication
First Author: Amet LE
Year: 2001
Journal: Mol Cell Neurosci
Title: Enhanced hippocampal long-term potentiation in mice lacking heparin-binding growth-associated molecule.
Volume: 17
Issue: 6
Pages: 1014-24
Publication
First Author: Hienola A
Year: 2004
Journal: Mol Cell Neurosci
Title: HB-GAM inhibits proliferation and enhances differentiation of neural stem cells.
Volume: 26
Issue: 1
Pages: 75-88
Publication
First Author: Imai S
Year: 2009
Journal: Bone
Title: Osteocyte-derived HB-GAM (pleiotrophin) is associated with bone formation and mechanical loading.
Volume: 44
Issue: 5
Pages: 785-94
Publication
First Author: Yokoi H
Year: 2012
Journal: Kidney Int
Title: Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis.
Volume: 81
Issue: 2
Pages: 160-9
Publication
First Author: Pavlov I
Year: 2006
Journal: Neuroscience
Title: Enhanced hippocampal GABAergic inhibition in mice overexpressing heparin-binding growth-associated molecule.
Volume: 139
Issue: 2
Pages: 505-11