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Search results 1 to 100 out of 196 for Ptpn2

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0.037s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication  
First Author: Wiede F
Year: 2014
Journal: Nat Commun
Title: PTPN2 attenuates T-cell lymphopenia-induced proliferation.
Volume: 5
Pages: 3073
Publication  
First Author: Hsieh WC
Year: 2020
Journal: JCI Insight
Title: PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis.
Volume: 5
Issue: 20
Publication
First Author: Wiede F
Year: 2017
Journal: J Exp Med
Title: PTPN2 regulates T cell lineage commitment and αβ versus γδ specification.
Volume: 214
Issue: 9
Pages: 2733-2758
Publication
First Author: LaFleur MW
Year: 2019
Journal: Nat Immunol
Title: PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity.
Volume: 20
Issue: 10
Pages: 1335-1347
Publication
First Author: Kleppe M
Year: 2010
Journal: Nat Genet
Title: Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia.
Volume: 42
Issue: 6
Pages: 530-5
Publication
First Author: Spalinger MR
Year: 2018
Journal: Cell Rep
Title: PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer.
Volume: 22
Issue: 7
Pages: 1835-1848
Publication
First Author: Spalinger MR
Year: 2015
Journal: Mucosal Immunol
Title: PTPN2 controls differentiation of CD4⁺ T cells and limits intestinal inflammation and intestinal dysbiosis.
Volume: 8
Issue: 4
Pages: 918-29
Publication
First Author: Flosbach M
Year: 2020
Journal: Cell Rep
Title: PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells.
Volume: 32
Issue: 4
Pages: 107957
Publication
First Author: Wiede F
Year: 2019
Journal: Diabetes
Title: T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities.
Volume: 68
Issue: 6
Pages: 1251-1266
Publication
First Author: Svensson MN
Year: 2019
Journal: J Clin Invest
Title: Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity.
Volume: 129
Issue: 3
Pages: 1193-1210
Publication
First Author: Li Y
Year: 2019
Journal: J Cell Mol Med
Title: PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy.
Volume: 23
Issue: 6
Pages: 4179-4195
Publication
First Author: Canale V
Year: 2023
Journal: Cell Mol Gastroenterol Hepatol
Title: PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice.
Volume: 16
Issue: 1
Pages: 39-62
Publication
First Author: Goh PK
Year: 2022
Journal: Sci Adv
Title: PTPN2 elicits cell autonomous and non-cell autonomous effects on antitumor immunity in triple-negative breast cancer.
Volume: 8
Issue: 8
Pages: eabk3338
Publication  
First Author: Hochheiser K
Year: 2021
Journal: J Exp Med
Title: Ptpn2 and KLRG1 regulate the generation and function of tissue-resident memory CD8+ T cells in skin.
Volume: 218
Issue: 6
Publication
First Author: Wiede F
Year: 2020
Journal: EMBO J
Title: PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours.
Volume: 39
Issue: 2
Pages: e103637
Publication
First Author: Spalinger MR
Year: 2020
Journal: Gastroenterology
Title: PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function.
Volume: 159
Issue: 5
Pages: 1763-1777.e14
Publication
First Author: Li Y
Year: 2018
Journal: Cell Physiol Biochem
Title: Overexpression of PTPN2 in Visceral Adipose Tissue Ameliorated Atherosclerosis via T Cells Polarization Shift in Diabetic Apoe-/- Mice.
Volume: 46
Issue: 1
Pages: 118-132
Publication      
First Author: Spalinger MR
Year: 2020
Journal: bioRxiv
Title: Identification of a Novel Susceptibility Marker for SARS-CoV-2 Infection in Human Subjects and Risk Mitigation with a Clinically Approved JAK Inhibitor in Human/Mouse Cells.
Publication
First Author: LaFleur MW
Year: 2019
Journal: Nat Commun
Title: A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system.
Volume: 10
Issue: 1
Pages: 1668
Publication
First Author: Wiede F
Year: 2011
Journal: J Clin Invest
Title: T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice.
Volume: 121
Issue: 12
Pages: 4758-74
Publication  
First Author: Marchelletta RR
Year: 2021
Journal: J Clin Invest
Title: T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling.
Volume: 131
Issue: 17
Publication  
First Author: Hering L
Year: 2021
Journal: Int J Mol Sci
Title: Macrophages Compensate for Loss of Protein Tyrosine Phosphatase N2 in Dendritic Cells to Protect from Elevated Colitis.
Volume: 22
Issue: 13
Publication  
First Author: Hering L
Year: 2020
Journal: Front Immunol
Title: Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance.
Volume: 11
Pages: 1856
Publication
First Author: Hassan SW
Year: 2010
Journal: PLoS One
Title: Increased susceptibility to dextran sulfate sodium induced colitis in the T cell protein tyrosine phosphatase heterozygous mouse.
Volume: 5
Issue: 1
Pages: e8868
Publication
First Author: Twohig JP
Year: 2019
Journal: Nat Immunol
Title: Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells.
Volume: 20
Issue: 4
Pages: 458-470
Publication
First Author: Spalinger MR
Year: 2022
Journal: Mucosal Immunol
Title: Loss of protein tyrosine phosphatase non-receptor type 2 reduces IL-4-driven alternative macrophage activation.
Volume: 15
Issue: 1
Pages: 74-83
Publication
First Author: Gurzov EN
Year: 2014
Journal: Cell Metab
Title: Hepatic oxidative stress promotes insulin-STAT-5 signaling and obesity by inactivating protein tyrosine phosphatase N2.
Volume: 20
Issue: 1
Pages: 85-102
Publication  
First Author: Katkeviciute E
Year: 2021
Journal: J Clin Invest
Title: Protein tyrosine phosphatase nonreceptor type 2 controls colorectal cancer development.
Volume: 131
Issue: 1
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Mosinger B Jr
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Cloning and characterization of a mouse cDNA encoding a cytoplasmic protein-tyrosine-phosphatase.
Volume: 89
Issue: 2
Pages: 499-503
Publication
First Author: Miyasaka H
Year: 1992
Journal: Mol Cell Biochem
Title: Molecular cloning, nucleotide sequence and expression of a cDNA encoding an intracellular protein tyrosine phosphatase, PTPase-2, from mouse testis and T-cells.
Volume: 118
Issue: 1
Pages: 91-8
Publication
First Author: You-Ten KE
Year: 1997
Journal: J Exp Med
Title: Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice.
Volume: 186
Issue: 5
Pages: 683-93
Publication
First Author: Simoncic PD
Year: 2002
Journal: Curr Biol
Title: The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3.
Volume: 12
Issue: 6
Pages: 446-53
Publication
First Author: Heinonen KM
Year: 2004
Journal: Blood
Title: T-cell protein tyrosine phosphatase deletion results in progressive systemic inflammatory disease.
Volume: 103
Issue: 9
Pages: 3457-64
Publication
First Author: van Vliet C
Year: 2005
Journal: Nat Immunol
Title: Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase.
Volume: 6
Issue: 3
Pages: 253-60
Publication
First Author: Fukushima A
Year: 2010
Journal: Diabetes
Title: T-cell protein tyrosine phosphatase attenuates STAT3 and insulin signaling in the liver to regulate gluconeogenesis.
Volume: 59
Issue: 8
Pages: 1906-14
Publication
First Author: Loh K
Year: 2012
Journal: Diabetologia
Title: T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice.
Volume: 55
Issue: 2
Pages: 468-78
Publication
First Author: Bourdeau A
Year: 2007
Journal: Blood
Title: TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}.
Volume: 109
Issue: 10
Pages: 4220-8
Publication
First Author: Wiede F
Year: 2012
Journal: PLoS One
Title: Strain-dependent differences in bone development, myeloid hyperplasia, morbidity and mortality in ptpn2-deficient mice.
Volume: 7
Issue: 5
Pages: e36703
Publication
First Author: Dupuis M
Year: 2003
Journal: J Immunol
Title: Gr-1+ myeloid cells lacking T cell protein tyrosine phosphatase inhibit lymphocyte proliferation by an IFN-gamma- and nitric oxide-dependent mechanism.
Volume: 171
Issue: 2
Pages: 726-32
Publication  
First Author: Lee H
Year: 2017
Journal: Sci Rep
Title: Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development.
Volume: 7
Pages: 45077
Publication
First Author: Sakaguchi AY
Year: 1992
Journal: Genomics
Title: Assignment of tyrosine-specific T-cell phosphatase to conserved syntenic groups on human chromosome 18 and mouse chromosome 18.
Volume: 12
Issue: 1
Pages: 151-4
Publication
First Author: Reddy RS
Year: 1995
Journal: DNA Cell Biol
Title: Alternative splicing generates four different forms of a non-transmembrane protein tyrosine phosphatase mRNA.
Volume: 14
Issue: 12
Pages: 1007-15
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:4355073
Age: embryonic day 8.5
Image: 4
Specimen Label: 8.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:4355073
Age: embryonic day 10.0
Image: 4
Specimen Label: 10
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:4355073
Age: embryonic day 11.5
Image: 4
Specimen Label: 11.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4355074
Age: postnatal adult
Image: 4
Specimen Label: TH
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4355074
Age: postnatal adult
Image: 4
Specimen Label: TE
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4355074
Age: postnatal adult
Image: 4
Specimen Label: KI
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:4355074
Age: postnatal adult
Image: 4
Specimen Label: LU
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:4355074
Age: postnatal adult
Image: 4
Specimen Label: MU
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:4355074
Age: postnatal adult
Image: 4
Specimen Label: SP
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4355074
Age: postnatal adult
Image: 4
Specimen Label: BR
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4355074
Age: postnatal adult
Image: 4
Specimen Label: HR
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4355074
Age: postnatal adult
Image: 4
Specimen Label: LI
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:4355199
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4355197
Age: postnatal adult
Image: 5
Specimen Label: KI
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4355199
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4355197
Age: postnatal adult
Image: 5
Specimen Label: TE
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4355199
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4355197
Age: postnatal adult
Image: 5
Specimen Label: OV
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4355200
Age: postnatal adult
Image: 5
Specimen Label: KI
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4355200
Age: postnatal adult
Image: 5
Specimen Label: TE
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4355072
Assay Type: Northern blot
Annotation Date: 2009-08-27
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4355200
Age: postnatal adult
Image: 5
Specimen Label: OV
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5286849
Assay Type: RT-PCR
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286923
Stage: TS23
Assay Id: MGI:5286958
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5286849
Assay Type: RT-PCR
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286926
Stage: TS26
Assay Id: MGI:5286958
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5286849
Assay Type: RT-PCR
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286927
Stage: TS27
Assay Id: MGI:5286958
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5286849
Assay Type: RT-PCR
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286928
Stage: TS28
Assay Id: MGI:5286958
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5286849
Assay Type: RT-PCR
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286928
Stage: TS28
Assay Id: MGI:5286958
Age: postnatal day 12
Specimen Label: P12
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5286849
Assay Type: RT-PCR
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286928
Stage: TS28
Assay Id: MGI:5286958
Age: postnatal day 20
Specimen Label: P20
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5286913
Assay Type: Western blot
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286923
Stage: TS23
Assay Id: MGI:5286964
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5286913
Assay Type: Western blot
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286926
Stage: TS26
Assay Id: MGI:5286964
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5286913
Assay Type: Western blot
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286927
Stage: TS27
Assay Id: MGI:5286964
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5286913
Assay Type: Western blot
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286928
Stage: TS28
Assay Id: MGI:5286964
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 5