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Search results 1 to 100 out of 364 for Ptpro

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Hits by Strain

Type Details Score
Gene
5800 | PTPRO
Type: gene
Organism: human
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Gene
100135074 | ptpro
Type: gene
Organism: frog, western clawed
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Gene
key_48594 | PTPRO
Type: gene
Organism: rabbit, European
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Gene
50677 | Ptpro
Type: gene
Organism: rat
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Gene
486664 | PTPRO
Type: gene
Organism: dog, domestic
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Gene
465314 | PTPRO
Type: gene
Organism: chimpanzee
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Gene
541043 | PTPRO
Type: gene
Organism: cattle
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Gene
373911 | PTPRO
Type: gene
Organism: chicken
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Gene
407676 | ptpro
Type: gene
Organism: zebrafish
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Gene
700811 | PTPRO
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR042996 | PTPRO
Type: Family
Description: PTPRO, also known as GLEPP1, is a receptor protein-tyrosine phosphatase containing an extracellular region that contains eight fibronectin FN III repeats and a single intracellular catalytic domain. GLEPP1 plays a role in axonal guidance [], promotes osteoclastic bone resorption [], mediates chemotaxis []and can act as a tumour suppressor []. Besides "full-length"GLEPP1, which is expressed in kidney and brain, a shorter variant exists that lacks the eight FN III repeats in the extracellular domain, called PTPROt, PTPphi, or PTP-oc, and is expressed in the hematopoietic lineage only, including osteoclasts [].
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Protein Coding Gene
MGI:1097152 | Ptpro
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
     
Probe: MGI:3618800
Assay Type: RT-PCR
Annotation Date: 2006-04-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Stage: TS28
Assay Id: MGI:3618811
Age: postnatal adult
Specimen Label: Ptpro
Detected: true
Specimen Num: 1
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Publication
19233845 | J:149775
First Author: Gobert RP
Year: 2009
Journal: J Biol Chem
Title: GLEPP1/protein-tyrosine phosphatase phi inhibitors block chemotaxis in vitro and in vivo and improve murine ulcerative colitis.
Volume: 284
Issue: 17
Pages: 11385-95
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Publication
37331584 | J:337827
 
First Author: Dong H
Year: 2023
Journal: Cancer Lett
Title: PTPRO suppresses lymph node metastasis of esophageal carcinoma by dephosphorylating MET.
Volume: 567
Pages: 216283
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Publication
19573017 | J:152241
First Author: Hower AE
Year: 2009
Journal: J Neurochem
Title: Dimerization of tyrosine phosphatase PTPRO decreases its activity and ability to inactivate TrkC.
Volume: 110
Issue: 5
Pages: 1635-47
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Publication
19924828 | J:162838
First Author: Kotani T
Year: 2010
Journal: J Comp Neurol
Title: Expression of PTPRO in the interneurons of adult mouse olfactory bulb.
Volume: 518
Issue: 2
Pages: 119-36
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Publication
35246496 | J:322726
First Author: Li Y
Year: 2022
Journal: J Immunol
Title: Protein Tyrosine Phosphatase PTPRO Signaling Couples Metabolic States to Control the Development of Granulocyte Progenitor Cells.
Volume: 208
Issue: 6
Pages: 1434-1444
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Publication
15673668 | J:98111
First Author: Chen B
Year: 2005
Journal: J Neurosci
Title: A novel substrate of receptor tyrosine phosphatase PTPRO is required for nerve growth factor-induced process outgrowth.
Volume: 25
Issue: 4
Pages: 880-8
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Publication
20804755 | J:164374
First Author: Kim M
Year: 2010
Journal: FEBS Lett
Title: Identification of ptpro as a novel target gene of Wnt signaling and its potential role as a receptor for Wnt.
Volume: 584
Issue: 18
Pages: 3923-8
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Publication
36535401 | J:334684
 
First Author: Shintani T
Year: 2023
Journal: Life Sci
Title: Deletion or inhibition of PTPRO prevents ectopic fat accumulation and induces healthy obesity with markedly reduced systemic inflammation.
Volume: 313
Pages: 121292
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Publication
12532410 | J:81473
First Author: Beltran PJ
Year: 2003
Journal: J Comp Neurol
Title: Expression of PTPRO during mouse development suggests involvement in axonogenesis and differentiation of NT-3 and NGF-dependent neurons.
Volume: 456
Issue: 4
Pages: 384-95
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Protein
E9Q612
Organism: Mus musculus/domesticus
Length: 1226  
Fragment?: false
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Protein
Q64501
Organism: Mus musculus/domesticus
Length: 42  
Fragment?: true
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Protein
Q4U213
Organism: Mus musculus/domesticus
Length: 287  
Fragment?: false
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Protein
Q80UH9
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: true
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Protein
Q9ERM5
Organism: Mus musculus/domesticus
Length: 1226  
Fragment?: false
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Protein
E9PVJ6
Organism: Mus musculus/domesticus
Length: 405  
Fragment?: false
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Protein
Q3UWY6
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: false
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Protein
E9Q4I1
Organism: Mus musculus/domesticus
Length: 1198  
Fragment?: false
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Protein
Q80W11
Organism: Mus musculus/domesticus
Length: 508  
Fragment?: true
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Protein
Q68FL5
Organism: Mus musculus/domesticus
Length: 509  
Fragment?: true
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Protein
Q4U214
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
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Protein
Q6P4T4
Organism: Mus musculus/domesticus
Length: 573  
Fragment?: true
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Protein
Q9JLU0
Organism: Mus musculus/domesticus
Length: 1198  
Fragment?: false
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Protein
Q60998
Organism: Mus musculus/domesticus
Length: 405  
Fragment?: false
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Protein
A0A0N4SUY2
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
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Publication
15519852 | -
First Author: Pixley FJ
Year: 2004
Journal: Trends Cell Biol
Title: CSF-1 regulation of the wandering macrophage: complexity in action.
Volume: 14
Issue: 11
Pages: 628-38
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Publication
14508512 | -
First Author: Motiwala T
Year: 2003
Journal: Oncogene
Title: Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas.
Volume: 22
Issue: 41
Pages: 6319-31
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Publication
15829633 | -
First Author: Stepanek L
Year: 2005
Journal: J Neurosci
Title: Receptor tyrosine phosphatases guide vertebrate motor axons during development.
Volume: 25
Issue: 15
Pages: 3813-23
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Publication
11585343 | -
First Author: Suhr SM
Year: 2001
Journal: J Bone Miner Res
Title: Antisense oligodeoxynucleotide evidence that a unique osteoclastic protein-tyrosine phosphatase is essential for osteoclastic resorption.
Volume: 16
Issue: 10
Pages: 1795-803
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Publication
19800005 | J:180562
First Author: Gonzalez-Brito MR
Year: 2009
Journal: Mol Cell Neurosci
Title: Protein tyrosine phosphatase receptor type O regulates development and function of the sensory nervous system.
Volume: 42
Issue: 4
Pages: 458-65
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Publication
20633639 | J:180550
First Author: Matozaki T
Year: 2010
Journal: Cell Signal
Title: Expression, localization, and biological function of the R3 subtype of receptor-type protein tyrosine phosphatases in mammals.
Volume: 22
Issue: 12
Pages: 1811-7
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Publication
11027578 | J:65083
First Author: Tomemori T
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Isolation and characterization of murine orthologue of PTP-BK.
Volume: 276
Issue: 3
Pages: 974-81
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Publication
25826083 | J:311797
First Author: Zhang W
Year: 2015
Journal: Oncotarget
Title: PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis.
Volume: 6
Issue: 11
Pages: 9420-33
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Publication
28871037 | J:248929
First Author: Jiang W
Year: 2017
Journal: J Neurosci
Title: Identification of Protein Tyrosine Phosphatase Receptor Type O (PTPRO) as a Synaptic Adhesion Molecule that Promotes Synapse Formation.
Volume: 37
Issue: 41
Pages: 9828-9843
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Publication
20398064 | J:169648
First Author: Murata Y
Year: 2010
Journal: Genes Cells
Title: Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn.
Volume: 15
Issue: 5
Pages: 513-24
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Publication
30082414 | J:265569
First Author: Yu Y
Year: 2018
Journal: J Neurosci
Title: Protein Tyrosine Phosphatase Receptor Type J (PTPRJ) Regulates Retinal Axonal Projections by Inhibiting Eph and Abl Kinases in Mice.
Volume: 38
Issue: 39
Pages: 8345-8363
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Publication
23516305 | J:196589
First Author: Gatto G
Year: 2013
Journal: J Neurosci
Title: Protein tyrosine phosphatase receptor type O inhibits trigeminal axon growth and branching by repressing TrkB and Ret signaling.
Volume: 33
Issue: 12
Pages: 5399-410
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Protein Coding Gene
MGP_CAROLIEiJ_G0029008 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031435 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031410 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031338 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031417 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031139 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1097152 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031879 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030507 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031099 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031256 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031207 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031340 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031247 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031911 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030600 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022771 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030058 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
11086029 | J:65903
First Author: Wharram BL
Year: 2000
Journal: J Clin Invest
Title: Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate.
Volume: 106
Issue: 10
Pages: 1281-90
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Publication
7592997 | J:42332
First Author: Pixley FJ
Year: 1995
Journal: J Biol Chem
Title: A heteromorphic protein-tyrosine phosphatase, PTP phi, is regulated by CSF-1 in macrophages.
Volume: 270
Issue: 45
Pages: 27339-47
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Publication
10792603 | J:63367
First Author: Wang R
Year: 2000
Journal: Kidney Int
Title: Molecular cloning, expression, and distribution of glomerular epithelial protein 1 in developing mouse kidney.
Volume: 57
Issue: 5
Pages: 1847-59
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Publication
28166196 | J:243384
First Author: Wakim J
Year: 2017
Journal: Oncogene
Title: The PTPROt tyrosine phosphatase functions as an obligate haploinsufficient tumor suppressor in vivo in B-cell chronic lymphocytic leukemia.
Volume: 36
Issue: 26
Pages: 3686-3694
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Publication
19244239 | J:149771
First Author: Sheng MH
Year: 2009
Journal: J Biol Chem
Title: Targeted transgenic expression of an osteoclastic transmembrane protein-tyrosine phosphatase in cells of osteoclastic lineage increases bone resorption and bone loss in male young adult mice.
Volume: 284
Issue: 17
Pages: 11531-45
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Publication
30622194 | J:284436
 
First Author: Roth L
Year: 2019
Journal: Sci Signal
Title: Phosphorylation of the phosphatase PTPROt at Tyr399 is a molecular switch that controls osteoclast activity and bone mass in vivo.
Volume: 12
Issue: 563
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GXD Expression
GXD Expression
   
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2656446
Age: postnatal adult
Image: 4
Specimen Label: Brain
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2656446
Age: postnatal adult
Image: 4
Specimen Label: Kidney
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:2656446
Age: postnatal adult
Image: 4
Specimen Label: Bone Marrow
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2656446
Age: postnatal adult
Image: 4
Specimen Label: Lung
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2656446
Age: postnatal adult
Image: 4
Specimen Label: Liver
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2656446
Age: postnatal adult
Image: 4
Specimen Label: Spleen
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2656446
Age: postnatal adult
Image: 4
Specimen Label: Thymus
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:2656446
Age: postnatal adult
Image: 4
Specimen Label: Intestine
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2656446
Age: postnatal adult
Image: 4
Specimen Label: Heart
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:2656454
Age: postnatal adult
Specimen Label: None
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2656454
Age: postnatal adult
Specimen Label: None
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:2656454
Age: postnatal adult
Specimen Label: None
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2656442
Assay Type: Northern blot
Annotation Date: 2003-05-06
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2656454
Age: postnatal adult
Specimen Label: None
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2656443
Assay Type: RT-PCR
Annotation Date: 2003-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2656487
Age: postnatal adult
Image: 5
Specimen Label: Brain
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:2656443
Assay Type: RT-PCR
Annotation Date: 2003-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2656487
Age: postnatal adult
Image: 5
Specimen Label: Kidney
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2656443
Assay Type: RT-PCR
Annotation Date: 2003-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:2656487
Age: postnatal adult
Image: 5
Specimen Label: Bone Marrow
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3035973
Assay Type: RT-PCR
Annotation Date: 2004-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647021
Stage: TS21
Assay Id: MGI:3035980
Age: embryonic day 13.0
Specimen Label: Novel PTP (D28)
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3625067
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3625068
Age: postnatal
Specimen Label: brain - total
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3625067
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3625068
Age: postnatal
Specimen Label: cortex
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3625067
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755028
Stage: TS28
Assay Id: MGI:3625068
Age: postnatal
Specimen Label: brain medulla
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3625067
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:3625068
Age: postnatal
Specimen Label: cerebellum
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3625067
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:3625068
Age: postnatal
Specimen Label: brainstem
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3625067
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:3625068
Age: postnatal
Specimen Label: olfactory bulb
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3625067
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3625068
Age: postnatal
Specimen Label: spinal cord
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3625067
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3625068
Age: postnatal
Specimen Label: eye
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3625067
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915328
Stage: TS28
Assay Id: MGI:3625068
Age: postnatal
Specimen Label: harderian gland
Detected: true
Specimen Num: 9
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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