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Search results 1 to 88 out of 88 for Purb

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Hits by Category

Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Maamar H
Year: 2013
Journal: Genes Dev
Title: linc-HOXA1 is a noncoding RNA that represses Hoxa1 transcription in cis.
Volume: 27
Issue: 11
Pages: 1260-71
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Knapp AM
Year: 2007
Journal: J Biol Chem
Title: Structure-function analysis of mouse Pur beta II. Conformation altering mutations disrupt single-stranded DNA and protein interactions crucial to smooth muscle alpha-actin gene repression.
Volume: 282
Issue: 49
Pages: 35899-909
GXD Expression      
Probe: MGI:6491307
Assay Type: Western blot
Annotation Date: 2021-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6491532
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6491307
Assay Type: Western blot
Annotation Date: 2021-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6491532
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6491307
Assay Type: Western blot
Annotation Date: 2021-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6491532
Age: postnatal adult
Specimen Label: KO
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6491307
Assay Type: Western blot
Annotation Date: 2021-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6491532
Age: postnatal adult
Specimen Label: KO
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6491290
Assay Type: RT-PCR
Annotation Date: 2021-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604828
Stage: TS28
Assay Id: MGI:6491545
Age: postnatal
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6491290
Assay Type: RT-PCR
Annotation Date: 2021-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604828
Stage: TS28
Assay Id: MGI:6491545
Age: postnatal
Specimen Label: dKO
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6491290
Assay Type: RT-PCR
Annotation Date: 2021-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604828
Stage: TS28
Assay Id: MGI:6491545
Age: postnatal
Specimen Label: WT
Detected: true
Specimen Num: 3
Publication
First Author: Kelm RJ Jr
Year: 1997
Journal: J Biol Chem
Title: Sequence of cDNAs encoding components of vascular actin single-stranded DNA-binding factor 2 establish identity to Puralpha and Purbeta.
Volume: 272
Issue: 42
Pages: 26727-33
Publication
First Author: Gupta M
Year: 2003
Journal: J Biol Chem
Title: Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure.
Volume: 278
Issue: 45
Pages: 44935-48
Publication  
First Author: Jia L
Year: 2020
Journal: Mol Metab
Title: Purβ promotes hepatic glucose production by increasing Adcy6 transcription.
Volume: 31
Pages: 85-97
Publication
First Author: Yano H
Year: 1999
Journal: Exp Cell Res
Title: Identification of (CAG)(n) and (CGG)(n) repeat-binding proteins, CAGERs expressed in mature neurons of the mouse brain.
Volume: 251
Issue: 2
Pages: 388-400
Publication
First Author: Wortman MJ
Year: 2005
Journal: Biochim Biophys Acta
Title: Mechanism of DNA binding and localized strand separation by Pur alpha and comparison with Pur family member, Pur beta.
Volume: 1743
Issue: 1-2
Pages: 64-78
Publication
First Author: Rumora AE
Year: 2013
Journal: Biochemistry
Title: Structural basis of multisite single-stranded DNA recognition and ACTA2 repression by purine-rich element binding protein B (Purβ).
Volume: 52
Issue: 26
Pages: 4439-50
Publication
First Author: Rumora AE
Year: 2016
Journal: Biochemistry
Title: Electrostatic and Hydrophobic Interactions Mediate Single-Stranded DNA Recognition and Acta2 Repression by Purine-Rich Element-Binding Protein B.
Volume: 55
Issue: 19
Pages: 2794-805
Publication
First Author: Kelm RJ Jr
Year: 1999
Journal: J Biol Chem
Title: Molecular interactions between single-stranded DNA-binding proteins associated with an essential MCAT element in the mouse smooth muscle alpha-actin promoter.
Volume: 274
Issue: 20
Pages: 14238-45
Publication
First Author: Ferris LA
Year: 2021
Journal: Mol Cell Biochem
Title: Purine-rich element binding protein B attenuates the coactivator function of myocardin by a novel molecular mechanism of smooth muscle gene repression.
Volume: 476
Issue: 8
Pages: 2899-2916
Publication
First Author: Knapp AM
Year: 2006
Journal: J Biol Chem
Title: Nucleoprotein interactions governing cell type-dependent repression of the mouse smooth muscle alpha-actin promoter by single-stranded DNA-binding proteins Pur alpha and Pur beta.
Volume: 281
Issue: 12
Pages: 7907-18
Publication
First Author: Zhang A
Year: 2008
Journal: Am J Physiol Cell Physiol
Title: Serum response factor neutralizes Pur alpha- and Pur beta-mediated repression of the fetal vascular smooth muscle alpha-actin gene in stressed adult cardiomyocytes.
Volume: 294
Issue: 3
Pages: C702-14
Publication
First Author: van Rooij E
Year: 2009
Journal: Dev Cell
Title: A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance.
Volume: 17
Issue: 5
Pages: 662-73
Publication
First Author: Subramanian SV
Year: 2004
Journal: Mol Biol Cell
Title: Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators.
Volume: 15
Issue: 10
Pages: 4532-43
Publication
First Author: Tsika RW
Year: 2010
Journal: J Biol Chem
Title: TEAD-1 overexpression in the mouse heart promotes an age-dependent heart dysfunction.
Volume: 285
Issue: 18
Pages: 13721-35
Publication
First Author: Tkatchenko TV
Year: 2009
Journal: Physiol Genomics
Title: Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease.
Volume: 39
Issue: 3
Pages: 160-8
Publication      
First Author: The Jackson Laboratory DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX Interspecific Backcross BSS and BSB Public Mapping Data
Publication
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: He B
Year: 1992
Journal: J Bacteriol
Title: Escherichia coli purB gene: cloning, nucleotide sequence, and regulation by purR.
Volume: 174
Issue: 1
Pages: 130-6
Publication
First Author: Wong LJ
Year: 1995
Journal: Genomics
Title: Characterization of the cDNA and the gene encoding murine adenylosuccinate lyase.
Volume: 28
Issue: 2
Pages: 341-3
Protein Domain
Type: Domain
Description: This domain is found at the C terminus of adenylosuccinate lyase (ASL; PurB in Escherichia coli). It has been identified in bacteria, eukaryotes and archaea and is found together with the lyase domain . ASL catalyses the cleavage of succinylaminoimidazole carboxamide ribotide to aminoimidazole carboxamide ribotide and fumarate and the cleavage of adenylosuccinate to adenylate and fumarate [].
Publication
First Author: Sleiman D
Year: 2021
Journal: Science
Title: A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes.
Volume: 372
Issue: 6541
Pages: 516-520
Protein Domain
Type: Family
Description: This family includes N6-succino-2-amino-2'-deoxyadenylate synthase PurZ from phages. It is involved in the synthesis of the atypical nucleotide dZTP (2-amino-2'-deoxyadenosine-5'-triphosphate) and in the synthesis of N6-succino-2-amino-2'-deoxyadenylate, which undergoes defumarylation and phosphorylation respectively by host PurB and guanylate/nucleoside diphosphate kinases to give dZTP (2-amino-2'-deoxyadenosine-5'-triphosphate). dZTP is integrated into the viral genome instead of adenine by the viral polymerase. This Z-base probably completely replaces adenosine and forms a triple bond to the opposite T-base. The resulting non-standard viral DNA is called Z-genome. The chemically modified DNA is probably harder for the host bacteria to digest with nucleases or restriction enzymes [, ].
Publication
First Author: Yang Y
Year: 2023
Journal: Stem Cells
Title: LncCMRR Plays an Important Role in Cardiac Differentiation by Regulating the Purb/Flk1 Axis.
Volume: 41
Issue: 1
Pages: 11-25
Publication
First Author: Zhou Y
Year: 2021
Journal: Science
Title: A widespread pathway for substitution of adenine by diaminopurine in phage genomes.
Volume: 372
Issue: 6541
Pages: 512-516