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Search results 1 to 100 out of 112 for Rab14

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
51552 | RAB14
Type: gene
Organism: human
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Gene
493231 | rab14
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR030702 | Rab14
Type: Family
Description: Ras-related protein Rab14 is a small GTPase that mediates endocytic recycling and functions in phagosome maturation [, ]. Rab14 and its exchange factor FAM116 regulates the specific endocytic transport of ADAM10 and thereby N-cadherin shedding and cell motility [, ]. Rab14 regulates claudin-2 trafficking, which is required for epithelial morphogenesis []. It regulates apical targeting in polarised epithelial cells []. Rab14 also regulates the interaction of phagosomes with early endocytic compartments and the maturation of macrophage phagosomes containing the fungal pathogen Candida albicans []. Drosophila Rab14 mediates phagocytosis in the immune response to Staphylococcus aureus [].
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Gene
94197 | Rab14
Type: gene
Organism: rat
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Gene
474818 | RAB14
Type: gene
Organism: dog, domestic
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Gene
744531 | RAB14
Type: gene
Organism: chimpanzee
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Gene
539180 | RAB14
Type: gene
Organism: cattle
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Gene
417119 | RAB14
Type: gene
Organism: chicken
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Gene
373104 | rab14
Type: gene
Organism: zebrafish
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Gene
699837 | RAB14
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1915615 | Rab14
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25644001 | J:229649
First Author: Okai B
Year: 2015
Journal: Infect Immun
Title: Rab14 regulates maturation of macrophage phagosomes containing the fungal pathogen Candida albicans and outcome of the host-pathogen interaction.
Volume: 83
Issue: 4
Pages: 1523-35
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Protein
Q50HX0
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Protein
Q50HX2
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Protein
Q50HX4
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Publication
18429929 | -
First Author: Kitt KN
Year: 2008
Journal: Traffic
Title: Rab14 regulates apical targeting in polarized epithelial cells.
Volume: 9
Issue: 7
Pages: 1218-31
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Publication
24694596 | -
First Author: Lu R
Year: 2014
Journal: Mol Biol Cell
Title: Rab14 regulation of claudin-2 trafficking modulates epithelial permeability and lumen morphogenesis.
Volume: 25
Issue: 11
Pages: 1744-54
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Publication
24119134 | -
First Author: Garg A
Year: 2014
Journal: Cell Microbiol
Title: Drosophila Rab14 mediates phagocytosis in the immune response to Staphylococcus aureus.
Volume: 16
Issue: 2
Pages: 296-310
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Publication
22595666 | -
First Author: Prekeris R
Year: 2012
Journal: Dev Cell
Title: The art of "cut and run": the role of Rab14 GTPase in regulating N-cadherin shedding and cell motility.
Volume: 22
Issue: 5
Pages: 909-10
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Publication
22595670 | -
First Author: Linford A
Year: 2012
Journal: Dev Cell
Title: Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells.
Volume: 22
Issue: 5
Pages: 952-66
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Publication
22569897 | -
First Author: Thi EP
Year: 2012
Journal: J Leukoc Biol
Title: Phosphatidylinositol 3-kinases and their roles in phagosome maturation.
Volume: 92
Issue: 3
Pages: 553-66
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Protein
Q50HX1
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false
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Protein
Q91V41
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Protein
Q50HX3
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false
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Publication
21238925 | J:168572
First Author: Ueno H
Year: 2011
Journal: Dev Cell
Title: KIF16B/Rab14 molecular motor complex is critical for early embryonic development by transporting FGF receptor.
Volume: 20
Issue: 1
Pages: 60-71
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Protein Coding Gene
MGP_CAROLIEiJ_G0023477 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025650 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025627 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025597 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025384 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1915615 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026068 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024846 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025362 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025457 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025581 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025488 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026126 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024594 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024915 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024934 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024394 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
- | J:73573
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, clone MGC: 6512 IMAGE: 2649852, mRNA, complete cds
Pages: BC009085
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Publication
36379959 | J:346915
First Author: Tu X
Year: 2022
Journal: Nat Commun
Title: Interruption of post-Golgi STING trafficking activates tonic interferon signaling.
Volume: 13
Issue: 1
Pages: 6977
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Publication
- | J:29505
     
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q50HW9
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false
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Publication
19702578 | -
First Author: Kelly EE
Year: 2009
Journal: Biol Cell
Title: Class I Rab11-family interacting proteins are binding targets for the Rab14 GTPase.
Volume: 102
Issue: 1
Pages: 51-62
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Protein Domain
IPR024224 | DENND6
Type: Family
Description: The DENND6 family of proteins includes DENND6A and B. They act as guanine nucleotide exchange factors (GEF) for RAB14 [].
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Protein Domain
IPR018307 | ABL9/DENND6_dom
Type: Domain
Description: This domain is found in late secretory protein Avl9, which is required for the generation of secretory vesicles as well as for actin polarization and polarized growth. It is also found in DENND6 proteins, which act as guanine nucleotide exchange factors (GEF) for RAB14 [].
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Publication
22908308 | J:191891
First Author: Chen Y
Year: 2012
Journal: J Cell Biol
Title: Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes.
Volume: 198
Issue: 4
Pages: 545-60
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Publication
30257216 | J:271643
First Author: Weimershaus M
Year: 2018
Journal: Cell Rep
Title: Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation.
Volume: 24
Issue: 13
Pages: 3568-3581
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Publication
23333653 | J:193684
First Author: Gronemeyer T
Year: 2013
Journal: FEBS Lett
Title: Localization of Rab proteins to peroxisomes: a proteomics and immunofluorescence study.
Volume: 587
Issue: 4
Pages: 328-38
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Publication
22238454 | J:181198
First Author: Weimershaus M
Year: 2012
Journal: J Immunol
Title: Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation.
Volume: 188
Issue: 4
Pages: 1840-6
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Publication
29089333 | J:262149
First Author: Li Z
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: Electrical pulse stimulation induces GLUT4 translocation in C2C12 myotubes that depends on Rab8A, Rab13, and Rab14.
Volume: 314
Issue: 5
Pages: E478-E493
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Protein
Q9D9V7
Organism: Mus musculus/domesticus
Length: 585  
Fragment?: false
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Protein
Q8BH65
Organism: Mus musculus/domesticus
Length: 605  
Fragment?: false
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Publication
35819177 | J:329237
First Author: Rathan-Kumar S
Year: 2022
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Rab11FIP1-deficient mice develop spontaneous inflammation and show increased susceptibility to colon damage.
Volume: 323
Issue: 3
Pages: G239-G254
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Publication
15173169 | -
First Author: Junutula JR
Year: 2004
Journal: J Biol Chem
Title: Molecular characterization of Rab11 interactions with members of the family of Rab11-interacting proteins.
Volume: 279
Issue: 32
Pages: 33430-7
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Publication
14532427 | -
 
First Author: Prekeris R
Year: 2003
Journal: ScientificWorldJournal
Title: Rabs, Rips, FIPs, and endocytic membrane traffic.
Volume: 3
Pages: 870-80
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Protein Domain
IPR037789 | FIP_classI
Type: Family
Description: Rab GTPases recruit various effector proteins to organelles and vesicles. Rab11-family interacting proteins (FIPs) are involved in mediating the role of Rab11. FIPs can be divided into three classes: class I FIPs (Rip11/Rab11-FIP5, RCP/RAB11FIP1, and FIP2) which contain a C2 domain after N terminus of the protein, class II FIPs (FIP3 and FIP4) which contain two EF-hands and a proline rich region, and class III FIPs (FIP1) which exhibits no homology to known protein domains. All FIP proteins contain a highly conserved, 20-amino acid motif at the C terminus of the protein, known as Rab11/25 binding domain (RBD). Class I FIPs are thought to bind to endocytic membranes via their C2 domain, which interacts directly with phospholipids. Class II FIPs do not have any membrane binding domains leaving much to speculate about the mechanism involving FIP3 and FIP4 interactions with endocytic membranes []. Class I FIPs, but not the class II FIPs, also interact with Rab14 [].The exact function of the Rab11 and FIP interaction is unknown, but there is speculation that it involves the role of forming a targeting complex that recruits a group of proteins involved in membrane transport to organelles. Recent studies have identified several Rab11-FIP complex-binding proteins that regulate distinct membrane traffic pathways [].This family consist of class I FIPs.
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Protein
Q80U56
Organism: Mus musculus/domesticus
Length: 649  
Fragment?: false
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Protein
A0A286YDD5
Organism: Mus musculus/domesticus
Length: 255  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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