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Search results 1 to 100 out of 148 for Rab15

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Hits by Strain

Type Details Score
Protein Domain
IPR041826 | Rab15
Type: Family
Description: Rab15 colocalizes with the transferrin receptor in early endosome compartments, but not with late endosomal markers. It codistributes with Rab4 and Rab5 on early/sorting endosomes, and with Rab11 on pericentriolar recycling endosomes. It is believed to function as an inhibitory GTPase that regulates distinct steps in early endocytic trafficking [, ]. Rabs are regulated by GTPase activating proteins (GAPs), which interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP. Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization. Most Rab GTPases contain a lipid modification site at the C terminus, with sequence motifs CC, CXC, or CCX. Lipid binding is essential for membrane attachment, a key feature of most Rab proteins [, ].
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Protein
Q0PD40
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
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Gene
376267 | RAB15
Type: gene
Organism: human
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Gene
549126 | rab15
Type: gene
Organism: frog, western clawed
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Gene
106999457 | RAB15
Type: gene
Organism: macaque, rhesus
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Gene
299156 | Rab15
Type: gene
Organism: rat
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Gene
611466 | RAB15
Type: gene
Organism: dog, domestic
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Gene
467484 | RAB15
Type: gene
Organism: chimpanzee
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Gene
614507 | RAB15
Type: gene
Organism: cattle
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Gene
429955 | RAB15
Type: gene
Organism: chicken
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Gene
436590 | rab15
Type: gene
Organism: zebrafish
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Protein Coding Gene
MGI:1916865 | Rab15
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10837464 | -
First Author: Zuk PA
Year: 2000
Journal: J Biol Chem
Title: Rab15 differentially regulates early endocytic trafficking.
Volume: 275
Issue: 35
Pages: 26754-64
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Publication
10428799 | -
First Author: Zuk PA
Year: 1999
Journal: J Biol Chem
Title: Rab15 mediates an early endocytic event in Chinese hamster ovary cells.
Volume: 274
Issue: 32
Pages: 22303-12
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Protein
Q91YW0
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Gene
387849 | REP15
Type: gene
Organism: human
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Protein
Q3TYH2
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
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Protein
Q8K386
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
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Protein
Q3TYB1
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
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Publication
10196122 | -
First Author: Dumas JJ
Year: 1999
Journal: Structure
Title: Structural basis of activation and GTP hydrolysis in Rab proteins.
Volume: 7
Issue: 4
Pages: 413-23
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Publication
11387043 | -
First Author: Stenmark H
Year: 2001
Journal: Genome Biol
Title: The Rab GTPase family.
Volume: 2
Issue: 5
Pages: REVIEWS3007
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Protein
Q9D7T1
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
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Publication
16195351 | -
First Author: Strick DJ
Year: 2005
Journal: Mol Biol Cell
Title: Rab15 effector protein: a novel protein for receptor recycling from the endocytic recycling compartment.
Volume: 16
Issue: 12
Pages: 5699-709
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Publication
21795538 | J:174506
First Author: Lai HC
Year: 2011
Journal: J Neurosci
Title: In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord.
Volume: 31
Issue: 30
Pages: 10859-71
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Protein Coding Gene
MGP_CAROLIEiJ_G0017873 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019866 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019799 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019803 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1916865 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020255 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019160 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019579 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019695 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019682 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019767 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019721 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020291 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018926 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019212 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029630 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018720 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:7529958
Assay Type: RT-PCR
Annotation Date: 2023-09-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684623
Stage: TS23
Assay Id: MGI:7529979
Age: embryonic day 15.5
Image: S4
Specimen Label: FL (E15.5)
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7529958
Assay Type: RT-PCR
Annotation Date: 2023-09-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:7529979
Age: embryonic day 17.5
Image: S4
Specimen Label: FL (E17.5)
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7529958
Assay Type: RT-PCR
Annotation Date: 2023-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283427
Stage: TS27
Assay Id: MGI:7529979
Age: postnatal newborn
Image: S4
Specimen Label: S.I.
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7529958
Assay Type: RT-PCR
Annotation Date: 2023-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529979
Age: postnatal adult
Image: S4
Specimen Label: Adult brain
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4845011
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1611817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848771
Age: embryonic day 10.5
Note: Staining is present in the mandibular arch.
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5824399
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752924
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5824501
Age: embryonic day 16.5
Image: 2E wt
Note: Expression in Merkel cells of vibrissa.
Specimen Label: 2E wt
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:5824399
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752924
Stage: TS24
Assay Id: MGI:5824501
Age: embryonic day 16.5
Image: 2E -/-
Note: Expression is lost in the mutant mouse.
Specimen Label: 2E -/-
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:5824399
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5824501
Age: embryonic day 16.5
Image: 2D wt
Note: Authors report expression in developing hair cells.
Specimen Label: 2D wt
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5824399
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619424
Stage: TS24
Assay Id: MGI:5824501
Age: embryonic day 16.5
Image: 2D -/-
Note: Expression is lost in the mutant mouse.
Specimen Label: 2D -/-
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:5824399
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5824501
Age: postnatal day 0
Image: 2C wt
Specimen Label: 2C wt
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5824399
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3521627
Stage: TS27
Assay Id: MGI:5824501
Age: postnatal day 0
Image: 2C -/-
Specimen Label: 2C -/-
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5824399
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616417
Stage: TS17
Assay Id: MGI:5824501
Age: embryonic day 10.5
Image: 2A -/-
Note: No expression in dorsal part of neural tube.
Specimen Label: 2A -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5824399
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5824501
Age: embryonic day 10.5
Image: 2A wt
Note: Expression in dorsal part of neural tube.
Specimen Label: 2A wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3718617
Assay Type: RNA in situ
Annotation Date: 2007-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606212
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:3718653
Age: embryonic day 8.25
Image: S5-left
Note: Expression was highly enriched in endoderm.
Specimen Label: S5-left
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3718617
Assay Type: RNA in situ
Annotation Date: 2007-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606215
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3718653
Age: embryonic day 9.5
Image: S5-right
Note: Expression was highly enriched in endoderm.
Specimen Label: S5-right
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4845011
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1638817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848771
Age: embryonic day 10.5
Note: Staining is present in the maxillary process.
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 1
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Publication
12578829 | J:83108
First Author: Fukuda M
Year: 2003
Journal: J Biol Chem
Title: Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.
Volume: 278
Issue: 17
Pages: 15373-80
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Publication
37042948 | J:340074
First Author: Wu J
Year: 2023
Journal: Blood Adv
Title: EHBP1L1, an apicobasal polarity regulator, is critical for nuclear polarization during enucleation of erythroblasts.
Volume: 7
Issue: 14
Pages: 3382-3394
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Publication
21377456 | J:169829
First Author: Pyrgaki C
Year: 2011
Journal: Dev Biol
Title: Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion.
Volume: 353
Issue: 1
Pages: 38-49
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Publication
25758223 | J:220468
First Author: Walentin K
Year: 2015
Journal: Development
Title: A Grhl2-dependent gene network controls trophoblast branching morphogenesis.
Volume: 142
Issue: 6
Pages: 1125-36
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Publication
17328885 | J:122516
First Author: Sherwood RI
Year: 2007
Journal: Dev Biol
Title: Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
Volume: 304
Issue: 2
Pages: 541-55
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:342609
       
First Author: UniProt
Year: 2021
Title: Electronic Gene Ontology annotations created by ARBA machine learning models
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Protein Coding Gene
MGI:1913782 | Rep15
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
500366 | Rep15
Type: gene
Organism: rat
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Gene
738255 | REP15
Type: gene
Organism: chimpanzee
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Gene
614599 | REP15
Type: gene
Organism: cattle
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Gene
100686017 | REP15
Type: gene
Organism: dog, domestic
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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