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Search results 1 to 100 out of 366 for Rab27a

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Hits by Strain

Type Details Score
Gene
5873 | RAB27A
Type: gene
Organism: human
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Gene
493339 | rab27a
Type: gene
Organism: frog, western clawed
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Gene
50645 | Rab27a
Type: gene
Organism: rat
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Gene
608699 | RAB27A
Type: gene
Organism: dog, domestic
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Gene
453455 | RAB27A
Type: gene
Organism: chimpanzee
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Gene
618035 | RAB27A
Type: gene
Organism: cattle
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Gene
415410 | RAB27A
Type: gene
Organism: chicken
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Gene
570907 | rab27a
Type: gene
Organism: zebrafish
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Gene
697741 | RAB27A
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1861441 | Rab27a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15690086 | J:95915
First Author: Kasai K
Year: 2005
Journal: J Clin Invest
Title: Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation.
Volume: 115
Issue: 2
Pages: 388-96
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Publication
32570938 | J:303286
 
First Author: Gross T
Year: 2020
Journal: Cells
Title: Rab27a Contributes to the Processing of Inflammatory Pain in Mice.
Volume: 9
Issue: 6
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Publication
14617806 | J:95342
First Author: Tolmachova T
Year: 2004
Journal: Mol Biol Cell
Title: A general role for Rab27a in secretory cells.
Volume: 15
Issue: 1
Pages: 332-44
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Publication
27733578 | J:331009
First Author: Ramadass M
Year: 2017
Journal: J Leukoc Biol
Title: Rab27a regulates GM-CSF-dependent priming of neutrophil exocytosis.
Volume: 101
Issue: 3
Pages: 693-702
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Publication
11266472 | J:67600
First Author: Stinchcombe JC
Year: 2001
Journal: J Cell Biol
Title: Rab27a is required for regulated secretion in cytotoxic T lymphocytes.
Volume: 152
Issue: 4
Pages: 825-34
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Publication
11266470 | J:67601
First Author: Hume AN
Year: 2001
Journal: J Cell Biol
Title: Rab27a regulates the peripheral distribution of melanosomes in melanocytes.
Volume: 152
Issue: 4
Pages: 795-808
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Publication
23986549 | J:209545
First Author: Kim JD
Year: 2013
Journal: J Leukoc Biol
Title: An essential role for Rab27a GTPase in eosinophil exocytosis.
Volume: 94
Issue: 6
Pages: 1265-74
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Publication
14722103 | J:166024
First Author: Fukuda M
Year: 2004
Journal: J Biol Chem
Title: Rabphilin and Noc2 are recruited to dense-core vesicles through specific interaction with Rab27A in PC12 cells.
Volume: 279
Issue: 13
Pages: 13065-75
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Publication
10859366 | J:63231
First Author: Wilson SM
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: A mutation in Rab27a causes the vesicle transport defects observed in ashen mice.
Volume: 97
Issue: 14
Pages: 7933-8
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Publication
17090228 | J:114299
First Author: Munafó DB
Year: 2007
Journal: Biochem J
Title: Rab27a is a key component of the secretory machinery of azurophilic granules in granulocytes.
Volume: 402
Issue: 2
Pages: 229-39
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Publication
25951179 | J:235344
First Author: Hou Y
Year: 2015
Journal: PLoS One
Title: Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion.
Volume: 10
Issue: 5
Pages: e0125596
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Publication
14978221 | J:91408
First Author: Futter CE
Year: 2004
Journal: Mol Biol Cell
Title: The role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cells.
Volume: 15
Issue: 5
Pages: 2264-75
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Publication
11228153 | J:134370
First Author: Wu X
Year: 2001
Journal: J Cell Sci
Title: Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle.
Volume: 114
Issue: Pt 6
Pages: 1091-100
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Publication
17351642 | J:126381
First Author: Jancic C
Year: 2007
Journal: Nat Cell Biol
Title: Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes.
Volume: 9
Issue: 4
Pages: 367-78
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Publication
37641131 | J:348898
First Author: Bastos N
Year: 2023
Journal: J Transl Med
Title: SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression.
Volume: 21
Issue: 1
Pages: 578
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Publication
32355248 | J:297787
First Author: Kren N
Year: 2020
Journal: Sci Rep
Title: Rab27a plays a dual role in metastatic propensity of pancreatic cancer.
Volume: 10
Issue: 1
Pages: 7390
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Publication
18940603 | J:155185
First Author: Chavas LM
Year: 2008
Journal: Structure
Title: Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a.
Volume: 16
Issue: 10
Pages: 1468-77
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Publication
12051743 | J:169802
First Author: Kuroda TS
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Synaptotagmin-like protein 5: a novel Rab27A effector with C-terminal tandem C2 domains.
Volume: 293
Issue: 3
Pages: 899-906
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Publication
11886590 | J:105323
First Author: Hume AN
Year: 2002
Journal: Traffic
Title: The leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytes.
Volume: 3
Issue: 3
Pages: 193-202
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Publication
12590134 | J:83162
First Author: Fukuda M
Year: 2003
Journal: J Biol Chem
Title: Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.
Volume: 278
Issue: 17
Pages: 15390-6
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Publication
18779337 | J:142540
First Author: Kim SH
Year: 2008
Journal: Infect Immun
Title: Recruitment of Rab27a to phagosomes controls microbial antigen cross-presentation by dendritic cells.
Volume: 76
Issue: 11
Pages: 5373-80
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Publication
18768935 | J:139663
First Author: Kimura T
Year: 2008
Journal: J Cell Sci
Title: The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines.
Volume: 121
Issue: Pt 18
Pages: 3092-8
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Publication
15572405 | J:94444
First Author: Gibbs D
Year: 2004
Journal: J Cell Sci
Title: Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes.
Volume: 117
Issue: Pt 26
Pages: 6473-83
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Publication
18559336 | J:140259
First Author: Figueiredo AC
Year: 2008
Journal: J Biol Chem
Title: Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes.
Volume: 283
Issue: 34
Pages: 23209-16
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Publication
20939018 | J:350164
First Author: Kariya Y
Year: 2011
Journal: J Bone Miner Res
Title: Rab27a and Rab27b are involved in stimulation-dependent RANKL release from secretory lysosomes in osteoblastic cells.
Volume: 26
Issue: 4
Pages: 689-703
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Publication
17698919 | J:128370
First Author: Hume AN
Year: 2007
Journal: J Cell Sci
Title: Rab27a and MyoVa are the primary Mlph interactors regulating melanosome transport in melanocytes.
Volume: 120
Issue: Pt 17
Pages: 3111-22
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Publication
20877725 | J:165107
First Author: Liu D
Year: 2010
Journal: PLoS One
Title: Distinct role of rab27a in granule movement at the plasma membrane and in the cytosol of NK cells.
Volume: 5
Issue: 9
Pages: e12870
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Publication
12070017 | J:77395
First Author: Novak EK
Year: 2002
Journal: Blood
Title: The regulation of platelet-dense granules by Rab27a in the ashen mouse, a model of Hermansky-Pudlak and Griscelli syndromes, is granule-specific and dependent on genetic background.
Volume: 100
Issue: 1
Pages: 128-35
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Publication
27927751 | J:246195
First Author: Matsunaga K
Year: 2017
Journal: J Cell Sci
Title: Rab2a and Rab27a cooperatively regulate the transition from granule maturation to exocytosis through the dual effector Noc2.
Volume: 130
Issue: 3
Pages: 541-550
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Publication
11773082 | J:75312
First Author: Kuroda TS
Year: 2002
Journal: J Biol Chem
Title: The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.
Volume: 277
Issue: 11
Pages: 9212-8
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Publication
18801842 | J:176566
First Author: Merrins MJ
Year: 2008
Journal: J Physiol
Title: Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic beta-cells.
Volume: 586
Issue: 22
Pages: 5367-81
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Publication
28589930 | J:250384
 
First Author: Boucher JM
Year: 2017
Journal: Nat Commun
Title: Dynamic alterations in decoy VEGF receptor-1 stability regulate angiogenesis.
Volume: 8
Pages: 15699
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Publication
27702998 | J:338771
First Author: Johnson JL
Year: 2016
Journal: J Biol Chem
Title: Identification of Neutrophil Exocytosis Inhibitors (Nexinhibs), Small Molecule Inhibitors of Neutrophil Exocytosis and Inflammation: DRUGGABILITY OF THE SMALL GTPase Rab27a.
Volume: 291
Issue: 50
Pages: 25965-25982
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Publication
22375060 | J:197700
First Author: Singh RK
Year: 2012
Journal: J Cell Sci
Title: Rab27a-mediated protease release regulates neutrophil recruitment by allowing uropod detachment.
Volume: 125
Issue: Pt 7
Pages: 1652-6
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Publication
21160031 | J:171174
First Author: Bolasco G
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Loss of Rab27 function results in abnormal lung epithelium structure in mice.
Volume: 300
Issue: 3
Pages: C466-76
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Publication
28978688 | J:251070
First Author: Alexander M
Year: 2017
Journal: J Immunol
Title: Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli.
Volume: 199
Issue: 10
Pages: 3559-3570
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Publication
18991284 | J:141404
First Author: Pachlopnik Schmid J
Year: 2008
Journal: Eur J Immunol
Title: A Griscelli syndrome type 2 murine model of hemophagocytic lymphohistiocytosis (HLH).
Volume: 38
Issue: 11
Pages: 3219-25
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Publication
27991490 | J:243452
 
First Author: Cheeseman LP
Year: 2016
Journal: Nat Commun
Title: Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes.
Volume: 7
Pages: 13726
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Publication
32240120 | J:313415
First Author: Okunishi K
Year: 2020
Journal: J Clin Invest
Title: Exophilin-5 regulates allergic airway inflammation by controlling IL-33-mediated Th2 responses.
Volume: 130
Issue: 7
Pages: 3919-3935
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Publication
17587407 | J:289015
First Author: Mizuno K
Year: 2007
Journal: Traffic
Title: Rab27b regulates mast cell granule dynamics and secretion.
Volume: 8
Issue: 7
Pages: 883-92
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Publication
17384153 | J:120307
First Author: Tolmachova T
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Rab27b regulates number and secretion of platelet dense granules.
Volume: 104
Issue: 14
Pages: 5872-7
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Protein
Q544U7
Organism: Mus musculus/domesticus
Length: 221  
Fragment?: false
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Publication
17761531 | J:145238
First Author: Gomi H
Year: 2007
Journal: Mol Biol Cell
Title: Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane.
Volume: 18
Issue: 11
Pages: 4377-86
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Publication
11266473 | J:111253
First Author: Haddad EK
Year: 2001
Journal: J Cell Biol
Title: Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice.
Volume: 152
Issue: 4
Pages: 835-42
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Publication
18266782 | J:150917
First Author: Holt O
Year: 2008
Journal: Traffic
Title: Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse.
Volume: 9
Issue: 4
Pages: 446-57
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Publication
21746860 | J:175690
First Author: Johnson JL
Year: 2011
Journal: Infect Immun
Title: Increased survival and reduced neutrophil infiltration of the liver in Rab27a- but not Munc13-4-deficient mice in lipopolysaccharide-induced systemic inflammation.
Volume: 79
Issue: 9
Pages: 3607-18
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Publication
- | J:24758
 
First Author: Lane PW
Year: 1977
Journal: Mouse News Lett
Title: New mutations and enzyme variants
Volume: 57
Pages: 18
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Publication
22042600 | J:179724
First Author: Chen G
Year: 2012
Journal: Glia
Title: Lysosomal exocytosis in Schwann cells contributes to axon remyelination.
Volume: 60
Issue: 2
Pages: 295-305
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Publication
6322428 | J:7366
First Author: Langdon WY
Year: 1984
Journal: Virology
Title: Relationship between a retroviral germ line reintegration and a new mutation at the ashen locus in B10.F mice. Retroviral integration and an ashen mutation.
Volume: 133
Issue: 1
Pages: 183-90
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Publication
18940604 | J:155184
First Author: Kukimoto-Niino M
Year: 2008
Journal: Structure
Title: Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases.
Volume: 16
Issue: 10
Pages: 1478-90
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Publication
12122117 | J:79756
First Author: Barral DC
Year: 2002
Journal: J Clin Invest
Title: Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome.
Volume: 110
Issue: 2
Pages: 247-57
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Publication
23403622 | J:196461
First Author: Jessen B
Year: 2013
Journal: Blood
Title: The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2.
Volume: 121
Issue: 15
Pages: 2943-51
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Publication
26864340 | J:232799
First Author: Sepulveda FE
Year: 2016
Journal: Blood
Title: Polygenic mutations in the cytotoxicity pathway increase susceptibility to develop HLH immunopathology in mice.
Volume: 127
Issue: 17
Pages: 2113-21
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Publication
23115246 | J:193760
First Author: Monfregola J
Year: 2012
Journal: J Biol Chem
Title: MUNC13-4 protein regulates the oxidative response and is essential for phagosomal maturation and bacterial killing in neutrophils.
Volume: 287
Issue: 53
Pages: 44603-18
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Publication
11887186 | J:75876
First Author: Wu XS
Year: 2002
Journal: Nat Cell Biol
Title: Identification of an organelle receptor for myosin-Va.
Volume: 4
Issue: 4
Pages: 271-8
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Publication
23671284 | J:202776
First Author: Hou Y
Year: 2013
Journal: J Biol Chem
Title: EPI64B acts as a GTPase-activating protein for Rab27B in pancreatic acinar cells.
Volume: 288
Issue: 27
Pages: 19548-57
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Publication
29074498 | J:259065
First Author: Truman-Rosentsvit M
Year: 2018
Journal: Blood
Title: Ferritin is secreted via 2 distinct nonclassical vesicular pathways.
Volume: 131
Issue: 3
Pages: 342-352
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Publication
- | J:4458
First Author: Lane PW
Year: 1979
Journal: J Hered
Title: Ashen, a new color mutation on chromosome 9 of the mouse.
Volume: 70
Issue: 2
Pages: 133-135
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Publication
12907454 | J:86678
First Author: Tiwari S
Year: 2003
Journal: Blood
Title: A role for Rab27b in NF-E2-dependent pathways of platelet formation.
Volume: 102
Issue: 12
Pages: 3970-9
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Publication
23160464 | J:193137
First Author: Sepulveda FE
Year: 2013
Journal: Blood
Title: Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11.
Volume: 121
Issue: 4
Pages: 595-603
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Publication
21525430 | J:175669
First Author: Chiang L
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Rab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland.
Volume: 301
Issue: 2
Pages: C507-21
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Publication
26845357 | J:234027
First Author: Hou Y
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Genetic deletion of Rab27B in pancreatic acinar cells affects granules size and has inhibitory effects on amylase secretion.
Volume: 471
Issue: 4
Pages: 610-5
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Publication
30042153 | J:265547
First Author: Binenbaum Y
Year: 2018
Journal: Cancer Res
Title: Transfer of miRNA in Macrophage-Derived Exosomes Induces Drug Resistance in Pancreatic Adenocarcinoma.
Volume: 78
Issue: 18
Pages: 5287-5299
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Publication
23281710 | J:211540
First Author: Singh RK
Year: 2013
Journal: FEBS J
Title: Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion.
Volume: 280
Issue: 3
Pages: 892-903
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Publication
36214220 | J:331542
 
First Author: Bauer KM
Year: 2022
Journal: JCI Insight
Title: CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis.
Volume: 7
Issue: 19
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Publication
17062724 | J:137593
First Author: Chintala S
Year: 2007
Journal: Blood
Title: The Slc35d3 gene, encoding an orphan nucleotide sugar transporter, regulates platelet-dense granules.
Volume: 109
Issue: 4
Pages: 1533-40
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Publication
23460904 | J:198276
First Author: Wavre-Shapton ST
Year: 2013
Journal: PLoS One
Title: Conditional ablation of the choroideremia gene causes age-related changes in mouse retinal pigment epithelium.
Volume: 8
Issue: 2
Pages: e57769
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Publication
20049711 | J:339189
First Author: Pachlopnik Schmid J
Year: 2009
Journal: EMBO Mol Med
Title: Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice.
Volume: 1
Issue: 2
Pages: 112-24
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Publication
18629000 | J:139279
First Author: Chan WT
Year: 2008
Journal: PLoS One
Title: Murine leukemia virus spreading in mice impaired in the biogenesis of secretory lysosomes and Ca2+-regulated exocytosis.
Volume: 3
Issue: 7
Pages: e2713
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Publication
27076615 | J:235681
First Author: Meng Z
Year: 2016
Journal: Am J Physiol Cell Physiol
Title: Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome.
Volume: 310
Issue: 11
Pages: C942-54
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Publication
26084661 | J:283026
 
First Author: Alexander M
Year: 2015
Journal: Nat Commun
Title: Exosome-delivered microRNAs modulate the inflammatory response to endotoxin.
Volume: 6
Pages: 7321
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Publication
30967557 | J:285941
First Author: Song L
Year: 2019
Journal: Nat Commun
Title: KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a.
Volume: 10
Issue: 1
Pages: 1639
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Publication
20138020 | J:158634
First Author: Kimura T
Year: 2010
Journal: Arch Biochem Biophys
Title: Actin assembly controlled by GDP-Rab27a is essential for endocytosis of the insulin secretory membrane.
Volume: 496
Issue: 1
Pages: 33-7
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Publication
20362548 | J:160347
First Author: Kimura T
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Glucose-induced translocation of coronin 3 regulates the retrograde transport of the secretory membrane in the pancreatic beta-cells.
Volume: 395
Issue: 3
Pages: 318-23
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Publication
28716933 | J:244659
First Author: Ritter AT
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Cortical actin recovery at the immunological synapse leads to termination of lytic granule secretion in cytotoxic T lymphocytes.
Volume: 114
Issue: 32
Pages: E6585-E6594
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Publication
11865063 | J:74984
First Author: Yi Z
Year: 2002
Journal: Mol Cell Biol
Title: The Rab27a/granuphilin complex regulates the exocytosis of insulin-containing dense-core granules.
Volume: 22
Issue: 6
Pages: 1858-67
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Publication
11964381 | J:76844
First Author: El-Amraoui A
Year: 2002
Journal: EMBO Rep
Title: MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes.
Volume: 3
Issue: 5
Pages: 463-70
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Publication
11178108 | J:67620
 
First Author: Ramalho JS
Year: 2001
Journal: BMC Genet
Title: Chromosomal mapping, gene structure and characterization of the human and murine RAB27B gene.
Volume: 2
Pages: 2
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Publication
23716592 | J:204576
First Author: Johnson JL
Year: 2013
Journal: Mol Cell Biol
Title: Upregulation of the Rab27a-dependent trafficking and secretory mechanisms improves lysosomal transport, alleviates endoplasmic reticulum stress, and reduces lysosome overload in cystinosis.
Volume: 33
Issue: 15
Pages: 2950-62
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Publication
26683831 | J:246573
First Author: Yamaoka M
Year: 2016
Journal: J Cell Sci
Title: PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a.
Volume: 129
Issue: 3
Pages: 637-49
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Publication
12401133 | J:132081
 
First Author: Ramalho JS
Year: 2002
Journal: BMC Cell Biol
Title: Rapid degradation of dominant-negative Rab27 proteins in vivo precludes their use in transgenic mouse models.
Volume: 3
Pages: 26
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Publication
28954823 | J:249191
First Author: Capece T
Year: 2017
Journal: J Cell Biol
Title: A novel intracellular pool of LFA-1 is critical for asymmetric CD8+ T cell activation and differentiation.
Volume: 216
Issue: 11
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