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Search results 1 to 100 out of 308 for Rab7

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Hits by Pathway

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Hits by Strain

Type Details Score
Protein Coding Gene
MGI:105068 | Rab7
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:7482714
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Pattern: Punctate
Stage: TS01
Assay Id: MGI:7482802
Age: embryonic day 0.5
Image: 4a RAB7
Note: Punctate expression in periphery of cytoplasm near plasma membrane.
Specimen Label: 4a RAB7
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7482714
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Pattern: Regionally restricted
Stage: TS01
Assay Id: MGI:7482802
Age: embryonic day 0.5
Image: 4b RAB7
Note: Expression abnormally aggregated in cytoplasm, colocalized with actin.
Specimen Label: 4b RAB7
Detected: true
Specimen Num: 2
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Publication
8547311 | J:30549
First Author: Vitelli R
Year: 1995
Journal: Biochim Biophys Acta
Title: Cloning and expression analysis of the murine Rab7 cDNA.
Volume: 1264
Issue: 3
Pages: 268-70
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Publication
31932498 | J:285615
First Author: Yan H
Year: 2020
Journal: J Immunol
Title: B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-κB Activation for Antibody Class-Switching.
Volume: 204
Issue: 5
Pages: 1146-1157
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Publication
28860274 | J:247712
First Author: Liu K
Year: 2017
Journal: J Cell Biol
Title: WDR91 is a Rab7 effector required for neuronal development.
Volume: 216
Issue: 10
Pages: 3307-3321
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GXD Expression
GXD Expression
   
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:7464737
Age: embryonic day 6.2
Specimen Label: 6A rab7 WT
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:7464737
Age: embryonic day 6.2
Specimen Label: 6A rab7 mVam2-/-
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:7464737
Age: embryonic day 6.0
Specimen Label: S5A rab7 wild-type
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:7464737
Age: embryonic day 6.0
Specimen Label: S5A rab7 mVam2-/-
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Regionally restricted
Stage: TS08
Assay Id: MGI:7464737
Age: embryonic day 6.0
Note: Expression in visceral endoderm overlying extraembryonic ectoderm. Expression in apical vacuoles.
Specimen Label: S5C rab7 wild-type
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:7464561
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Regionally restricted
Stage: TS08
Assay Id: MGI:7464737
Age: embryonic day 6.0
Note: Expression in visceral endoderm overlying extraembryonic ectoderm. Expression in apical vacuoles.
Specimen Label: S5C rab7 mVam2-/-
Detected: true
Specimen Num: 10
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Publication
9585432 | J:47878
First Author: Chiariello M
Year: 1998
Journal: Mamm Genome
Title: Genetic mapping of the mouse Rab7 gene and pseudogene and of the human RAB7 homolog.
Volume: 9
Issue: 6
Pages: 448-52
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Publication
32229179 | J:299878
First Author: Roque NR
Year: 2020
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Rab7 controls lipid droplet-phagosome association during mycobacterial infection.
Volume: 1865
Issue: 8
Pages: 158703
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Protein
P51150
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
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Publication
38015641 | J:352242
 
First Author: Piper B
Year: 2024
Journal: J Clin Invest
Title: RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension.
Volume: 134
Issue: 3
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Publication
12972561 | J:163139
First Author: Mizuno K
Year: 2003
Journal: Mol Biol Cell
Title: Rabring7, a novel Rab7 target protein with a RING finger motif.
Volume: 14
Issue: 9
Pages: 3741-52
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Publication
23615463 | J:211733
First Author: Roy SG
Year: 2013
Journal: Autophagy
Title: Reciprocal effects of rab7 deletion in activated and neglected T cells.
Volume: 9
Issue: 7
Pages: 1009-23
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Publication
29712939 | J:278051
First Author: Matsumoto N
Year: 2018
Journal: Sci Rep
Title: Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment.
Volume: 8
Issue: 1
Pages: 6701
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Publication
8954989 | J:37577
First Author: Vitelli R
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Molecular cloning and expression analysis of the human Rab7 GTP-ase complementary deoxyribonucleic acid.
Volume: 229
Issue: 3
Pages: 887-90
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Publication
28588238 | J:270574
First Author: Takahashi K
Year: 2017
Journal: Sci Rep
Title: Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models.
Volume: 7
Issue: 1
Pages: 2817
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Publication
37878717 | J:346904
First Author: Wong YC
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Misregulation of mitochondria-lysosome contact dynamics in Charcot-Marie-Tooth Type 2B disease Rab7 mutant sensory peripheral neurons.
Volume: 120
Issue: 44
Pages: e2313010120
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Publication
12054610 | J:76385
First Author: Kim JY
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Rab7 gene is up-regulated by cholesterol-rich diet in the liver and artery.
Volume: 293
Issue: 1
Pages: 375-82
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Publication
16763563 | J:119021
First Author: Bhattacharya M
Year: 2006
Journal: EMBO J
Title: IL-6 and IL-12 specifically regulate the expression of Rab5 and Rab7 via distinct signaling pathways.
Volume: 25
Issue: 12
Pages: 2878-88
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Publication
25774384 | J:251546
First Author: Yan CH
Year: 2015
Journal: Biochim Biophys Acta
Title: CREG1 ameliorates myocardial fibrosis associated with autophagy activation and Rab7 expression.
Volume: 1852
Issue: 2
Pages: 353-64
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Publication
28465352 | J:246019
First Author: Zhang J
Year: 2017
Journal: J Biol Chem
Title: Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A.
Volume: 292
Issue: 25
Pages: 10328-10346
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Publication
25740947 | J:232623
First Author: Pone EJ
Year: 2015
Journal: J Immunol
Title: B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Volume: 194
Issue: 7
Pages: 3065-78
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Publication
38296463 | J:347159
First Author: Nakanishi-Matsui M
Year: 2024
Journal: Biol Pharm Bull
Title: Role of the Cytosolic Domain of the a3 Subunit of V-ATPase in the Interaction with Rab7 and Secretory Lysosome Trafficking in Osteoclasts.
Volume: 47
Issue: 1
Pages: 339-344
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Publication
30721447 | J:294776
First Author: Nian FS
Year: 2019
Journal: Mol Neurobiol
Title: Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B.
Volume: 56
Issue: 9
Pages: 6095-6105
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Publication
27777970 | J:236517
First Author: Fujiwara T
Year: 2016
Journal: JCI Insight
Title: PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.
Volume: 1
Issue: 17
Pages: e86330
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Publication
22990867 | J:187732
 
First Author: Kawamura N
Year: 2012
Journal: Nat Commun
Title: Delivery of endosomes to lysosomes via microautophagy in the visceral endoderm of mouse embryos.
Volume: 3
Pages: 1071
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Publication
37596294 | J:341086
First Author: Liang W
Year: 2023
Journal: Nat Commun
Title: Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired.
Volume: 14
Issue: 1
Pages: 5031
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Publication
32521258 | J:295945
First Author: Kawamura N
Year: 2020
Journal: Cell Rep
Title: Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism.
Volume: 31
Issue: 10
Pages: 107733
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Publication
19956673 | J:213901
First Author: Yamaguchi H
Year: 2009
Journal: PLoS Pathog
Title: An initial step of GAS-containing autophagosome-like vacuoles formation requires Rab7.
Volume: 5
Issue: 11
Pages: e1000670
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Publication
21683685 | J:174951
First Author: Sugaya K
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Mobility of late endosomal and lysosomal markers on phagosomes analyzed by fluorescence recovery after photobleaching.
Volume: 410
Issue: 2
Pages: 371-5
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Publication
38837607 | J:354515
First Author: Ke J
Year: 2024
Journal: Adv Sci (Weinh)
Title: Targeting Rab7-Rilp Mediated Microlipophagy Alleviates Lipid Toxicity in Diabetic Cardiomyopathy.
Volume: 11
Issue: 29
Pages: e2401676
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Publication
24549040 | J:206933
First Author: Farg MA
Year: 2014
Journal: Hum Mol Genet
Title: C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking.
Volume: 23
Issue: 13
Pages: 3579-95
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Publication
23708524 | J:224803
First Author: Lizaso A
Year: 2013
Journal: Autophagy
Title: β-adrenergic receptor-stimulated lipolysis requires the RAB7-mediated autolysosomal lipid degradation.
Volume: 9
Issue: 8
Pages: 1228-43
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Publication
38709385 | J:359059
First Author: Zierke L
Year: 2024
Journal: Cell Mol Life Sci
Title: Initiation of acute pancreatitis in mice is independent of fusion between lysosomes and zymogen granules.
Volume: 81
Issue: 1
Pages: 207
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Publication
33846297 | J:313840
First Author: Bai L
Year: 2021
Journal: Cell Death Dis
Title: Simvastatin accelerated motoneurons death in SOD1G93A mice through inhibiting Rab7-mediated maturation of late autophagic vacuoles.
Volume: 12
Issue: 4
Pages: 392
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Publication
29907658 | J:267235
First Author: Yap CC
Year: 2018
Journal: J Cell Biol
Title: Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes.
Volume: 217
Issue: 9
Pages: 3141-3159
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Publication
28264927 | J:249586
First Author: Li L
Year: 2017
Journal: J Cell Sci
Title: Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases.
Volume: 130
Issue: 8
Pages: 1475-1485
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Publication
38744829 | J:354513
First Author: Kim M
Year: 2024
Journal: Bone Res
Title: RUFY4 deletion prevents pathological bone loss by blocking endo-lysosomal trafficking of osteoclasts.
Volume: 12
Issue: 1
Pages: 29
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Publication
21248257 | J:169141
First Author: Sender V
Year: 2011
Journal: J Immunol
Title: Pulmonary surfactant protein A enhances endolysosomal trafficking in alveolar macrophages through regulation of Rab7.
Volume: 186
Issue: 4
Pages: 2397-411
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Protein Coding Gene
MGP_129S1SvImJ_G0031005 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030971 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030902 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030984 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030726 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_105068 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031441 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030093 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030668 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030777 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030901 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031468 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029808 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030174 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022362 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029636 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
25592972 | J:229208
First Author: Kizuka Y
Year: 2015
Journal: EMBO Mol Med
Title: An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease.
Volume: 7
Issue: 2
Pages: 175-89
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Publication
11172003 | J:79316
First Author: Cormont M
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic.
Volume: 98
Issue: 4
Pages: 1637-42
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Publication
19587007 | J:151709
First Author: Yao M
Year: 2009
Journal: J Immunol
Title: Late endosome/lysosome-localized Rab7b suppresses TLR9-initiated proinflammatory cytokine and type I IFN production in macrophages.
Volume: 183
Issue: 3
Pages: 1751-8
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Publication
22275436 | J:197308
First Author: Ohbayashi N
Year: 2012
Journal: J Cell Sci
Title: Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p150Glued complex in melanocytes.
Volume: 125
Issue: Pt 6
Pages: 1508-18
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Publication
17287360 | J:119738
First Author: Liu JJ
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport.
Volume: 104
Issue: 7
Pages: 2223-8
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Publication
25735755 | J:252004
First Author: Guo F
Year: 2015
Journal: J Cell Biochem
Title: Lyar Is a New Ligand for Retinal Pigment Epithelial Phagocytosis.
Volume: 116
Issue: 10
Pages: 2177-87
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Publication
30985297 | J:296116
First Author: Hirose T
Year: 2019
Journal: J Clin Invest
Title: ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.
Volume: 129
Issue: 5
Pages: 2145-2162
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Publication
27378698 | J:237861
First Author: Magalhaes J
Year: 2016
Journal: Hum Mol Genet
Title: Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease.
Volume: 25
Issue: 16
Pages: 3432-3445
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Publication
15588329 | J:95873
 
First Author: Fossale E
Year: 2004
Journal: BMC Neurosci
Title: Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis.
Volume: 5
Pages: 57
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Publication
15078902 | J:89488
First Author: Seaman MN
Year: 2004
Journal: J Cell Biol
Title: Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer.
Volume: 165
Issue: 1
Pages: 111-22
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
22854957 | J:186307
First Author: Peng C
Year: 2012
Journal: J Biol Chem
Title: Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.
Volume: 287
Issue: 39
Pages: 32861-73
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Publication
11042173 | J:67373
First Author: Bell AW
Year: 2001
Journal: J Biol Chem
Title: Proteomics characterization of abundant Golgi membrane proteins.
Volume: 276
Issue: 7
Pages: 5152-65
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Publication
23028046 | J:192731
First Author: Ha SD
Year: 2012
Journal: Mol Cell Biol
Title: Cellular adaptation to anthrax lethal toxin-induced mitochondrial cholesterol enrichment, hyperpolarization, and reactive oxygen species generation through downregulating MLN64 in macrophages.
Volume: 32
Issue: 23
Pages: 4846-60
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Publication
24334765 | J:209071
First Author: Qin Y
Year: 2014
Journal: Hum Mol Genet
Title: The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal function.
Volume: 23
Issue: 9
Pages: 2428-39
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
20152176 | J:157920
First Author: Zovein AC
Year: 2010
Journal: Dev Cell
Title: Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism.
Volume: 18
Issue: 1
Pages: 39-51
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
8521519 | J:30249
First Author: Carroll JM
Year: 1995
Journal: Cell
Title: Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis.
Volume: 83
Issue: 6
Pages: 957-68
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Publication
27294511 | J:238155
First Author: Safaiyan S
Year: 2016
Journal: Nat Neurosci
Title: Age-related myelin degradation burdens the clearance function of microglia during aging.
Volume: 19
Issue: 8
Pages: 995-8
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Publication
34588579 | J:312380
First Author: Sun-Wada GH
Year: 2021
Journal: Sci Rep
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