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Search results 1 to 100 out of 426 for Rac2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Gu Y
Year: 2003
Journal: Science
Title: Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases.
Volume: 302
Issue: 5644
Pages: 445-9
Publication
First Author: Abdel-Latif D
Year: 2004
Journal: Blood
Title: Rac2 is critical for neutrophil primary granule exocytosis.
Volume: 104
Issue: 3
Pages: 832-9
Publication
First Author: Koh AL
Year: 2005
Journal: Cell Immunol
Title: The role of Rac1 and Rac2 in bacterial killing.
Volume: 235
Issue: 2
Pages: 92-7
Publication
First Author: Yu H
Year: 2001
Journal: J Exp Med
Title: Deficiency of small GTPase Rac2 affects T cell activation.
Volume: 194
Issue: 7
Pages: 915-26
Publication
First Author: Hsu AP
Year: 2019
Journal: Blood
Title: Dominant activating RAC2 mutation with lymphopenia, immunodeficiency, and cytoskeletal defects.
Volume: 133
Issue: 18
Pages: 1977-1988
Publication
First Author: Ou X
Year: 1999
Journal: DNA Cell Biol
Title: Identification and functional characterization of the murine Rac2 gene promoter.
Volume: 18
Issue: 3
Pages: 253-63
Publication
First Author: Lim MB
Year: 2011
Journal: J Leukoc Biol
Title: Rac2 is required for the formation of neutrophil extracellular traps.
Volume: 90
Issue: 4
Pages: 771-6
Publication
First Author: Ceneri N
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production.
Volume: 37
Issue: 2
Pages: 328-340
Publication
First Author: Wang Y
Year: 2008
Journal: J Bone Miner Res
Title: Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.
Volume: 23
Issue: 2
Pages: 260-70
Publication
First Author: Li B
Year: 2000
Journal: Science
Title: Role of the guanosine triphosphatase Rac2 in T helper 1 cell differentiation.
Volume: 288
Issue: 5474
Pages: 2219-22
Publication
First Author: Sengupta A
Year: 2010
Journal: Blood
Title: Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo.
Volume: 116
Issue: 1
Pages: 81-4
Publication
First Author: Tao W
Year: 2002
Journal: Blood
Title: The TRQQKRP motif located near the C-terminus of Rac2 is essential for Rac2 biologic functions and intracellular localization.
Volume: 100
Issue: 5
Pages: 1679-88
Publication
First Author: Joshi S
Year: 2014
Journal: PLoS One
Title: Rac2 controls tumor growth, metastasis and M1-M2 macrophage differentiation in vivo.
Volume: 9
Issue: 4
Pages: e95893
Publication
First Author: Pradip D
Year: 2003
Journal: J Biol Chem
Title: Rac2 specificity in macrophage integrin signaling: potential role for Syk kinase.
Volume: 278
Issue: 43
Pages: 41661-9
Publication
First Author: Savina A
Year: 2009
Journal: Immunity
Title: The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells.
Volume: 30
Issue: 4
Pages: 544-55
Publication  
First Author: Baptista MA
Year: 2016
Journal: Nat Commun
Title: Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells.
Volume: 7
Pages: 12175
Publication
First Author: Dooley JL
Year: 2009
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Regulation of inflammation by Rac2 in immune complex-mediated acute lung injury.
Volume: 297
Issue: 6
Pages: L1091-102
Publication
First Author: Wheeler AP
Year: 2006
Journal: J Cell Sci
Title: Rac1 and Rac2 regulate macrophage morphology but are not essential for migration.
Volume: 119
Issue: Pt 13
Pages: 2749-57
Publication
First Author: Ojha N
Year: 2008
Journal: Free Radic Biol Med
Title: Assessment of wound-site redox environment and the significance of Rac2 in cutaneous healing.
Volume: 44
Issue: 4
Pages: 682-91
Publication
First Author: Yang FC
Year: 2000
Journal: Immunity
Title: Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells.
Volume: 12
Issue: 5
Pages: 557-68
Publication
First Author: Filippi MD
Year: 2004
Journal: Nat Immunol
Title: Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.
Volume: 5
Issue: 7
Pages: 744-51
Publication
First Author: Joshi S
Year: 2017
Journal: PLoS One
Title: Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype.
Volume: 12
Issue: 8
Pages: e0182851
Publication
First Author: Guo F
Year: 2008
Journal: Blood
Title: Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development.
Volume: 112
Issue: 5
Pages: 1767-75
Publication
First Author: Azim AC
Year: 2007
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Regulation of cyclooxygenase-2 expression by small GTPase Rac2 in bone marrow macrophages.
Volume: 293
Issue: 3
Pages: L668-73
Publication
First Author: Gomez JC
Year: 2008
Journal: Am J Pathol
Title: The role of Rac2 in regulating neutrophil production in the bone marrow and circulating neutrophil counts.
Volume: 173
Issue: 2
Pages: 507-17
Publication
First Author: Carstanjen D
Year: 2005
Journal: J Immunol
Title: Rac2 regulates neutrophil chemotaxis, superoxide production, and myeloid colony formation through multiple distinct effector pathways.
Volume: 174
Issue: 8
Pages: 4613-20
Publication
First Author: Roberts AW
Year: 1999
Journal: Immunity
Title: Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense.
Volume: 10
Issue: 2
Pages: 183-96
GXD Expression      
Probe: MGI:6181824
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191183
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Rac2
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6181824
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191183
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Rac2
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6181824
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6191183
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Rac2
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6181824
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6191183
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Rac2
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6181824
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191183
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Rac2
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6181824
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191183
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Rac2
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6181824
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191183
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Rac2
Detected: false
Specimen Num: 7
Publication
First Author: Peng HJ
Year: 2011
Journal: Mol Cell Biol
Title: The dual effect of Rac2 on phospholipase D2 regulation that explains both the onset and termination of chemotaxis.
Volume: 31
Issue: 11
Pages: 2227-40
Publication
First Author: Kim C
Year: 2001
Journal: J Immunol
Title: Rac2 is an essential regulator of neutrophil nicotinamide adenine dinucleotide phosphate oxidase activation in response to specific signaling pathways.
Volume: 166
Issue: 2
Pages: 1223-32
Publication
First Author: Li S
Year: 2002
Journal: J Immunol
Title: Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions.
Volume: 169
Issue: 9
Pages: 5043-51
Publication
First Author: Kalfa TA
Year: 2010
Journal: Haematologica
Title: Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen.
Volume: 95
Issue: 1
Pages: 27-35
Publication
First Author: Kang IS
Year: 2020
Journal: Sci Rep
Title: Opposing roles of hematopoietic-specific small GTPase Rac2 and the guanine nucleotide exchange factor Vav1 in osteoclast differentiation.
Volume: 10
Issue: 1
Pages: 7024
Publication
First Author: Arana E
Year: 2008
Journal: Immunity
Title: Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation.
Volume: 28
Issue: 1
Pages: 88-99
Publication
First Author: Walmsley MJ
Year: 2003
Journal: Science
Title: Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling.
Volume: 302
Issue: 5644
Pages: 459-62
Publication
First Author: Zhang J
Year: 2022
Journal: Arterioscler Thromb Vasc Biol
Title: Macrophage ALDH2 (Aldehyde Dehydrogenase 2) Stabilizing Rac2 Is Required for Efferocytosis Internalization and Reduction of Atherosclerosis Development.
Volume: 42
Issue: 6
Pages: 700-716
Publication
First Author: Croker BA
Year: 2002
Journal: J Immunol
Title: The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes.
Volume: 168
Issue: 7
Pages: 3376-86
Publication
First Author: Munugalavadla V
Year: 2007
Journal: Blood
Title: Genetic and pharmacologic evidence implicating the p85 alpha, but not p85 beta, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis.
Volume: 110
Issue: 5
Pages: 1612-20
Publication
First Author: Croker BA
Year: 2002
Journal: Immunol Cell Biol
Title: Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in T(H)1 responses.
Volume: 80
Issue: 3
Pages: 231-40
Publication
First Author: Thomas EK
Year: 2007
Journal: Cancer Cell
Title: Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease.
Volume: 12
Issue: 5
Pages: 467-78
Publication
First Author: Ramaswamy M
Year: 2007
Journal: J Immunol
Title: Cutting edge: Rac GTPases sensitize activated T cells to die via Fas.
Volume: 179
Issue: 10
Pages: 6384-8
Publication
First Author: Glogauer M
Year: 2003
Journal: J Immunol
Title: Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions.
Volume: 170
Issue: 11
Pages: 5652-7
Publication
First Author: Kim C
Year: 2006
Journal: J Leukoc Biol
Title: Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid.
Volume: 79
Issue: 1
Pages: 223-34
Publication
First Author: Mahankali M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2.
Volume: 108
Issue: 49
Pages: 19617-22
Publication
First Author: Faroudi M
Year: 2010
Journal: Blood
Title: Critical roles for Rac GTPases in T-cell migration to and within lymph nodes.
Volume: 116
Issue: 25
Pages: 5536-47
Publication
First Author: Mizukawa B
Year: 2011
Journal: Blood
Title: Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.
Volume: 118
Issue: 19
Pages: 5235-45
Publication
First Author: Cancelas JA
Year: 2005
Journal: Nat Med
Title: Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization.
Volume: 11
Issue: 8
Pages: 886-91
Publication
First Author: Kalfa TA
Year: 2006
Journal: Blood
Title: Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton.
Volume: 108
Issue: 12
Pages: 3637-45
Publication
First Author: Yamauchi A
Year: 2005
Journal: J Biol Chem
Title: Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain.
Volume: 280
Issue: 2
Pages: 953-64
Publication
First Author: Fattouh R
Year: 2013
Journal: PLoS One
Title: Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infection.
Volume: 8
Issue: 4
Pages: e61629
Publication
First Author: Yamauchi A
Year: 2004
Journal: J Immunol
Title: Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles.
Volume: 173
Issue: 10
Pages: 5971-9
Publication
First Author: Yao HY
Year: 2011
Journal: Biochim Biophys Acta
Title: Inhibition of Rac activity alleviates lipopolysaccharide-induced acute pulmonary injury in mice.
Volume: 1810
Issue: 7
Pages: 666-74
Publication
First Author: Dumont C
Year: 2009
Journal: Blood
Title: Rac GTPases play critical roles in early T-cell development.
Volume: 113
Issue: 17
Pages: 3990-8
Publication
First Author: Hall AB
Year: 2006
Journal: Immunity
Title: Requirements for Vav guanine nucleotide exchange factors and Rho GTPases in FcgammaR- and complement-mediated phagocytosis.
Volume: 24
Issue: 3
Pages: 305-16
Publication
First Author: Zhang H
Year: 2009
Journal: J Immunol
Title: Human neutrophils coordinate chemotaxis by differential activation of Rac1 and Rac2.
Volume: 183
Issue: 4
Pages: 2718-28
Publication
First Author: Goldberg SR
Year: 2012
Journal: Bone
Title: A 3D scanning confocal imaging method measures pit volume and captures the role of Rac in osteoclast function.
Volume: 51
Issue: 1
Pages: 145-52
Publication
First Author: Konstantinidis DG
Year: 2012
Journal: Blood
Title: Signaling and cytoskeletal requirements in erythroblast enucleation.
Volume: 119
Issue: 25
Pages: 6118-27
Publication
First Author: Sun CX
Year: 2004
Journal: Blood
Title: Rac1 is the small GTPase responsible for regulating the neutrophil chemotaxis compass.
Volume: 104
Issue: 12
Pages: 3758-65
Publication
First Author: Ji P
Year: 2008
Journal: Nat Cell Biol
Title: Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2.
Volume: 10
Issue: 3
Pages: 314-21
Publication
First Author: Ueyama T
Year: 2005
Journal: J Immunol
Title: Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome.
Volume: 175
Issue: 4
Pages: 2381-90
Publication
First Author: Distasi MR
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growth.
Volume: 296
Issue: 3
Pages: H877-86
Publication
First Author: Chang KH
Year: 2012
Journal: Blood
Title: Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival.
Volume: 120
Issue: 4
Pages: 800-11
Publication
First Author: Leung R
Year: 2011
Journal: Blood
Title: Sbds is required for Rac2-mediated monocyte migration and signaling downstream of RANK during osteoclastogenesis.
Volume: 117
Issue: 6
Pages: 2044-53
Publication
First Author: Speranza FJ
Year: 2013
Journal: J Leukoc Biol
Title: Macrophage migration arrest due to a winning balance of Rac2/Sp1 repression over β-catenin-induced PLD expression.
Volume: 94
Issue: 5
Pages: 953-62
Publication
First Author: Kogler M
Year: 2020
Journal: Cancer Res
Title: HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.
Volume: 80
Issue: 14
Pages: 3009-3022
Publication
First Author: Utomo A
Year: 2006
Journal: J Immunol
Title: Vav proteins in neutrophils are required for FcgammaR-mediated signaling to Rac GTPases and nicotinamide adenine dinucleotide phosphate oxidase component p40(phox).
Volume: 177
Issue: 9
Pages: 6388-97
Publication
First Author: Wang L
Year: 2006
Journal: Blood
Title: Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment.
Volume: 107
Issue: 1
Pages: 98-105
Publication
First Author: Morrison AR
Year: 2014
Journal: J Exp Med
Title: Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis.
Volume: 211
Issue: 10
Pages: 1957-68
Publication
First Author: Martin H
Year: 2013
Journal: J Clin Invest
Title: Pak and Rac GTPases promote oncogenic KIT-induced neoplasms.
Volume: 123
Issue: 10
Pages: 4449-63
Publication
First Author: Henderson RB
Year: 2010
Journal: J Exp Med
Title: A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival.
Volume: 207
Issue: 4
Pages: 837-53
Publication
First Author: Ramgolam VS
Year: 2010
Journal: PLoS One
Title: T cell LFA-1 engagement induces HuR-dependent cytokine mRNA stabilization through a Vav-1, Rac1/2, p38MAPK and MKK3 signaling cascade.
Volume: 5
Issue: 12
Pages: e14450
Publication
First Author: Ingram DA
Year: 2001
Journal: J Exp Med
Title: Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro.
Volume: 194
Issue: 1
Pages: 57-69
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory