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Search results 1 to 100 out of 295 for Rap1a

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Domain
Description: The structures of the immunity protein Rap1a , responsible for the inhibition and neutralization of Ssp1 endopeptidase, revealed two distinct folds. The structure of the Ssp1-Rap1a complex revealed a tightly bound heteromeric assembly with two effector molecules flanking a Rap1a dimer. The Rap1a subunit displays a compact globular structure constructed from five α-helices that assemble to form the highly stable symmetric dimer [].
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Srikannathasan V
Year: 2013
Journal: Acta Crystallogr D Biol Crystallogr
Title: Structural basis for type VI secreted peptidoglycan DL-endopeptidase function, specificity and neutralization in Serratia marcescens.
Volume: 69
Issue: Pt 12
Pages: 2468-82
Publication
First Author: Wang Y
Year: 2022
Journal: Cell Rep
Title: Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia.
Volume: 40
Issue: 8
Pages: 111259
Publication
First Author: Li Y
Year: 2007
Journal: J Immunol
Title: Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins.
Volume: 179
Issue: 12
Pages: 8322-31
Publication
First Author: Li L
Year: 2010
Journal: Cell Immunol
Title: Rap1A regulates generation of T regulatory cells via LFA-1-dependent and LFA-1-independent mechanisms.
Volume: 266
Issue: 1
Pages: 7-13
Protein
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
Publication
First Author: Stadtmann A
Year: 2011
Journal: Eur J Immunol
Title: Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin-dependent slow leukocyte rolling.
Volume: 41
Issue: 7
Pages: 2074-85
Publication
First Author: Huk DJ
Year: 2018
Journal: Thyroid
Title: Deletion of Rap1b, but not Rap1a or Epac1, Reduces Protein Kinase A-Mediated Thyroid Cancer.
Volume: 28
Issue: 9
Pages: 1153-1161
Publication
First Author: Dorn A
Year: 2012
Journal: Cell Immunol
Title: Rap1a deficiency modifies cytokine responses and MAPK-signaling in vitro and impairs the in vivo inflammatory response.
Volume: 276
Issue: 1-2
Pages: 187-95
Publication
First Author: Yan J
Year: 2008
Journal: Mol Cell Biol
Title: Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions.
Volume: 28
Issue: 18
Pages: 5803-10
Publication
First Author: Duchniewicz M
Year: 2006
Journal: Mol Cell Biol
Title: Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion.
Volume: 26
Issue: 2
Pages: 643-53
Publication
First Author: Jeyaraj SC
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells.
Volume: 303
Issue: 5
Pages: C499-511
Publication
First Author: Pan BX
Year: 2008
Journal: J Neurosci
Title: Enhanced cortico-amygdala efficacy and suppressed fear in absence of Rap1.
Volume: 28
Issue: 9
Pages: 2089-98
Publication
First Author: Awasthi A
Year: 2010
Journal: J Exp Med
Title: Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes.
Volume: 207
Issue: 9
Pages: 1923-38
Publication
First Author: Wang JC
Year: 2017
Journal: J Cell Sci
Title: The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse.
Volume: 130
Issue: 6
Pages: 1094-1109
Publication  
First Author: Lakshmikanthan S
Year: 2018
Journal: J Cell Sci
Title: Rap1B promotes VEGF-induced endothelial permeability and is required for dynamic regulation of the endothelial barrier.
Volume: 131
Issue: 1
Publication
First Author: Carmona G
Year: 2009
Journal: Blood
Title: Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis.
Volume: 113
Issue: 2
Pages: 488-97
Publication
First Author: Su W
Year: 2015
Journal: Blood
Title: Rap1 and its effector RIAM are required for lymphocyte trafficking.
Volume: 126
Issue: 25
Pages: 2695-703
Publication
First Author: Potla U
Year: 2014
Journal: J Clin Invest
Title: Podocyte-specific RAP1GAP expression contributes to focal segmental glomerulosclerosis-associated glomerular injury.
Volume: 124
Issue: 4
Pages: 1757-69
Publication
First Author: Wittchen ES
Year: 2013
Journal: PLoS One
Title: Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo.
Volume: 8
Issue: 9
Pages: e73070
Publication
First Author: Chrzanowska-Wodnicka M
Year: 2015
Journal: PLoS One
Title: Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature.
Volume: 10
Issue: 12
Pages: e0145689
Publication
First Author: Dower NA
Year: 1992
Journal: Mamm Genome
Title: Organization and chromosomal locations of Rap1a/Krev sequences in the mouse.
Volume: 3
Issue: 3
Pages: 162-7
Publication
First Author: Mediero A
Year: 2014
Journal: FASEB J
Title: Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements.
Volume: 28
Issue: 11
Pages: 4901-13
Publication
First Author: Stefanini L
Year: 2018
Journal: Blood
Title: Functional redundancy between RAP1 isoforms in murine platelet production and function.
Volume: 132
Issue: 18
Pages: 1951-1962
Publication
First Author: Xu W
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Small GTPase Rap1A/B Is Required for Lymphatic Development and Adrenomedullin-Induced Stabilization of Lymphatic Endothelial Junctions.
Volume: 38
Issue: 10
Pages: 2410-2422
Publication
First Author: Lakshmikanthan S
Year: 2011
Journal: Blood
Title: Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ₃.
Volume: 118
Issue: 7
Pages: 2015-26
Publication
First Author: Maddala R
Year: 2015
Journal: Dev Biol
Title: Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis.
Volume: 406
Issue: 1
Pages: 74-91
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Birukova AA
Year: 2015
Journal: Biochim Biophys Acta
Title: Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1.
Volume: 1852
Issue: 5
Pages: 778-91
Publication
First Author: Kitayama H
Year: 1989
Journal: Cell
Title: A ras-related gene with transformation suppressor activity.
Volume: 56
Issue: 1
Pages: 77-84
Publication
First Author: Wang Z
Year: 2006
Journal: Mol Cell Biol
Title: Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation.
Volume: 26
Issue: 6
Pages: 2130-45
Publication
First Author: Freeman SA
Year: 2017
Journal: J Cell Sci
Title: Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor.
Volume: 130
Issue: 1
Pages: 152-163
Publication
First Author: Khattar E
Year: 2019
Journal: Nat Commun
Title: Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy.
Volume: 10
Issue: 1
Pages: 5349
Publication
First Author: Salinas GF
Year: 2012
Journal: J Neuroimmunol
Title: Sustained Rap1 activation in autoantigen-specific T lymphocytes attenuates experimental autoimmune encephalomyelitis.
Volume: 250
Issue: 1-2
Pages: 35-43
GXD Expression      
Probe: MGI:4429596
Assay Type: Western blot
Annotation Date: 2010-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4429597
Age: postnatal
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4429596
Assay Type: Western blot
Annotation Date: 2010-02-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4429597
Age: postnatal
Specimen Label: -/-
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:4429596
Assay Type: Western blot
Annotation Date: 2010-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:4429597
Age: postnatal
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4429596
Assay Type: Western blot
Annotation Date: 2010-02-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:4429597
Age: postnatal
Specimen Label: -/-
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:5006824
Assay Type: RT-PCR
Annotation Date: 2011-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:5007476
Age: embryonic day 0.5
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5006824
Assay Type: RT-PCR
Annotation Date: 2011-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:5007476
Age: embryonic day 2.0
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5006824
Assay Type: RT-PCR
Annotation Date: 2011-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5007476
Age: embryonic day 3.5
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5910737
Assay Type: Western blot
Annotation Date: 2017-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:5910911
Age: embryonic day 16.0
Specimen Label: 5A WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5910737
Assay Type: Western blot
Annotation Date: 2017-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:5910911
Age: embryonic day 16.0
Specimen Label: 5A KD
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5910737
Assay Type: Western blot
Annotation Date: 2017-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:5910916
Age: embryonic day 16.0
Specimen Label: 5A WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5910737
Assay Type: Western blot
Annotation Date: 2017-10-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:5910916
Age: embryonic day 16.0
Specimen Label: 5A KD
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5006824
Assay Type: RT-PCR
Annotation Date: 2011-06-14
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:5007476
Age: postnatal
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5006824
Assay Type: RT-PCR
Annotation Date: 2011-06-14
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:5007476
Age: postnatal
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:7449120
Age: embryonic day 9.5
Specimen Label: Control
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:7449120
Age: embryonic day 9.5
Specimen Label: Control
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:7449120
Age: embryonic day 9.5
Specimen Label: Control
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:7449120
Age: embryonic day 9.5
Specimen Label: Cre/+
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:7449120
Age: embryonic day 9.5
Specimen Label: Cre/+
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:7449120
Age: embryonic day 9.5
Specimen Label: Cre/+
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:7449121
Age: embryonic day 10.5
Specimen Label: Control
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:7449121
Age: embryonic day 10.5
Specimen Label: Control
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:7449121
Age: embryonic day 10.5
Specimen Label: Control
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:7449121
Age: embryonic day 10.5
Specimen Label: Cre/+
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:7449121
Age: embryonic day 10.5
Specimen Label: Cre/+
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:7449121
Age: embryonic day 10.5
Specimen Label: Cre/+
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7449123
Age: embryonic day 12.5
Specimen Label: E12.5 Control
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7449123
Age: embryonic day 12.5
Specimen Label: E12.5 Control
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7449123
Age: embryonic day 12.5
Specimen Label: E12.5 Cre/+
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7449123
Age: embryonic day 12.5
Specimen Label: E12.5 Cre/+
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7449123
Age: embryonic day 13.5
Specimen Label: E13.5 Control
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7449123
Age: embryonic day 13.5
Specimen Label: E13.5 Control
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7449123
Age: embryonic day 13.5
Specimen Label: E13.5 Cre/+
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:7449123
Age: embryonic day 13.5
Specimen Label: E13.5 Cre/+
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610519
Stage: TS19
Assay Id: MGI:7449123
Age: embryonic day 11.5
Specimen Label: E11.5 Control
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610519
Stage: TS19
Assay Id: MGI:7449123
Age: embryonic day 11.5
Specimen Label: E11.5 Control
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610519
Stage: TS19
Assay Id: MGI:7449123
Age: embryonic day 11.5
Specimen Label: E11.5 Cre/+
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:7448891
Assay Type: Western blot
Annotation Date: 2023-03-31
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610519
Stage: TS19
Assay Id: MGI:7449123
Age: embryonic day 11.5
Specimen Label: E11.5 Cre/+
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:7464606
Assay Type: RT-PCR
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783827
Stage: TS27
Assay Id: MGI:7464632
Age: postnatal day 2
Image: 1
Specimen Label: P2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7464606
Assay Type: RT-PCR
Annotation Date: 2023-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7464632
Age: postnatal day 24
Image: 1
Specimen Label: P24
Detected: true
Specimen Num: 2