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Search results 1 to 93 out of 93 for Rasgrp3

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Hits by Strain

Type Details Score
Protein
Q2PHE9
Organism: Mus musculus/domesticus
Length: 691  
Fragment?: false
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Gene
25780 | RASGRP3
Type: gene
Organism: human
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Gene
100487452 | rasgrp3
Type: gene
Organism: frog, western clawed
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Gene
313874 | Rasgrp3
Type: gene
Organism: rat
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Gene
611329 | RASGRP3
Type: gene
Organism: dog, domestic
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Gene
470348 | RASGRP3
Type: gene
Organism: chimpanzee
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Gene
523745 | RASGRP3
Type: gene
Organism: cattle
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Gene
421460 | RASGRP3
Type: gene
Organism: chicken
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Gene
563441 | rasgrp3
Type: gene
Organism: zebrafish
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Gene
707225 | RASGRP3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:3028579 | Rasgrp3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR029645 | RASGRP3
Type: Family
Description: Guanine nucleotide exchange factors (GEFs) couple extracellular stimuli to Ras protein activation []. Rasguanyl-releasing protein 3 (RasGRP3) is an activator for H-Ras, R-Ras and Ras-associated protein-1/2 []. Its expression has been linked to several cancers [, , ].
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Gene
105374454 | RASGRP3-AS1
Type: gene
Organism: human
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Publication
27465532 | J:299351
First Author: Golec DP
Year: 2016
Journal: J Immunol
Title: RasGRP1 and RasGRP3 Are Required for Efficient Generation of Early Thymic Progenitors.
Volume: 197
Issue: 5
Pages: 1743-53
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Publication
21474816 | J:185701
First Author: Randhawa PK
Year: 2011
Journal: Circ Res
Title: The Ras activator RasGRP3 mediates diabetes-induced embryonic defects and affects endothelial cell migration.
Volume: 108
Issue: 10
Pages: 1199-208
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Publication
15545601 | J:94466
First Author: Aiba Y
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation.
Volume: 101
Issue: 47
Pages: 16612-7
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Publication
29490280 | J:271104
First Author: Moore AR
Year: 2018
Journal: Cell Rep
Title: GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma.
Volume: 22
Issue: 9
Pages: 2455-2468
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Publication
16301621 | J:108677
First Author: Coughlin JJ
Year: 2005
Journal: J Immunol
Title: RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling.
Volume: 175
Issue: 11
Pages: 7179-84
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Publication
15572660 | J:95118
First Author: Roberts DM
Year: 2004
Journal: Mol Cell Biol
Title: A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters.
Volume: 24
Issue: 24
Pages: 10515-28
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Publication
24779681 | -
 
First Author: Nagy Z
Year: 2014
Journal: Mol Cancer
Title: Function of RasGRP3 in the formation and progression of human breast cancer.
Volume: 13
Pages: 96
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Publication
20876802 | -
First Author: Yang D
Year: 2010
Journal: Cancer Res
Title: RasGRP3 contributes to formation and maintenance of the prostate cancer phenotype.
Volume: 70
Issue: 20
Pages: 7905-17
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Protein
Q6NZH9
Organism: Mus musculus/domesticus
Length: 691  
Fragment?: false
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Protein
Q69ZX7
Organism: Mus musculus/domesticus
Length: 693  
Fragment?: true
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Protein
A0A3Q4EC09
Organism: Mus musculus/domesticus
Length: 56  
Fragment?: true
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Protein
A0A3Q4EG32
Organism: Mus musculus/domesticus
Length: 69  
Fragment?: true
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Publication
10934204 | -
First Author: Rebhun JF
Year: 2000
Journal: J Biol Chem
Title: Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction.
Volume: 275
Issue: 45
Pages: 34901-8
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Publication
21602881 | -
First Author: Yang D
Year: 2011
Journal: Oncogene
Title: RasGRP3, a Ras activator, contributes to signaling and the tumorigenic phenotype in human melanoma.
Volume: 30
Issue: 45
Pages: 4590-4600
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Allele
Rasgrp3<em2Smoc> | MGI:7786928
Name: RAS, guanyl releasing protein 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
15894621 | J:99817
First Author: Regier DS
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Diacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signaling.
Volume: 102
Issue: 21
Pages: 7595-600
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Publication
16530850 | J:144136
First Author: Coughlin JJ
Year: 2006
Journal: Immunol Lett
Title: The role of RasGRPs in regulation of lymphocyte proliferation.
Volume: 105
Issue: 1
Pages: 77-82
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Publication
23308188 | J:195716
First Author: Golec DP
Year: 2013
Journal: PLoS One
Title: RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4.
Volume: 8
Issue: 1
Pages: e53300
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Publication
18172297 | J:131036
First Author: Ikuta S
Year: 2008
Journal: Cancer Res
Title: Crucial role of phospholipase C epsilon in skin inflammation induced by tumor-promoting phorbol ester.
Volume: 68
Issue: 1
Pages: 64-72
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Protein Coding Gene
MGP_CAROLIEiJ_G0021882 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024034 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023991 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023960 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023993 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023757 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3028579 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024438 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023237 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023731 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023860 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023826 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022983 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023304 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020869 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022794 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
       
Probe: MGI:3776271
Assay Type: RT-PCR
Annotation Date: 2008-04-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3776288
Age: embryonic day 13.0
Specimen Label: E13
Specimen Num: 3
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GXD Expression
GXD Expression
       
Probe: MGI:3776271
Assay Type: RT-PCR
Annotation Date: 2008-04-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3776288
Age: embryonic day 17.0
Specimen Label: E17
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:2304826
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827630
Age: embryonic day 14.5
Image: euxassay_006926_11
Specimen Label: euxassay_006926_11
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:2304826
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827630
Age: embryonic day 14.5
Image: euxassay_006926_12
Specimen Label: euxassay_006926_12
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2304826
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827630
Age: embryonic day 14.5
Image: euxassay_006926_13
Specimen Label: euxassay_006926_13
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:2304826
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4827630
Age: embryonic day 14.5
Image: euxassay_006926_14
Specimen Label: euxassay_006926_14
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6220388
Assay Type: RNA in situ
Annotation Date: 2024-07-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7666089
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
19100522 | J:146564
First Author: Stang SL
Year: 2009
Journal: Exp Hematol
Title: A proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells.
Volume: 37
Issue: 1
Pages: 122-134
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Publication
21822279 | J:176969
First Author: Costello I
Year: 2011
Journal: Nat Cell Biol
Title: The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation.
Volume: 13
Issue: 9
Pages: 1084-91
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Strain
MGI:7788773 | C57BL/6JSmoc-Rasgrp3<em2Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
26851222 | J:299348
First Author: Guo B
Year: 2016
Journal: J Immunol
Title: RasGRP1 Is an Essential Signaling Molecule for Development of B1a Cells with Autoantigen Receptors.
Volume: 196
Issue: 6
Pages: 2583-90
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Publication
23991094 | J:299167
First Author: Song X
Year: 2013
Journal: PLoS One
Title: RasGRPs are targets of the anti-cancer agent ingenol-3-angelate.
Volume: 8
Issue: 8
Pages: e72331
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Publication
22262848 | J:299313
First Author: Zhu M
Year: 2012
Journal: J Biol Chem
Title: The role of Ras guanine nucleotide releasing protein 4 in Fc epsilonRI-mediated signaling, mast cell function, and T cell development.
Volume: 287
Issue: 11
Pages: 8135-43
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Publication
17523924 | J:354164
First Author: Johnson JE
Year: 2007
Journal: Biochem J
Title: Differential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs.
Volume: 406
Issue: 2
Pages: 223-36
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Publication
22687285 | J:315062
First Author: Martínez-López N
Year: 2012
Journal: Gastroenterology
Title: Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.
Volume: 143
Issue: 3
Pages: 787-798.e13
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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