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Search results 1 to 87 out of 87 for Rasgrp4

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
115727 | RASGRP4
Type: gene
Organism: human
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Gene
529375 | RASGRP4
Type: gene
Organism: cattle
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Gene
558453 | rasgrp4
Type: gene
Organism: zebrafish
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Gene
719595 | RASGRP4
Type: gene
Organism: macaque, rhesus
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Gene
100496432 | rasgrp4
Type: gene
Organism: frog, western clawed
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Gene
170668 | Rasgrp4
Type: gene
Organism: rat
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Gene
484528 | RASGRP4
Type: gene
Organism: dog, domestic
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Gene
468867 | RASGRP4
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2386851 | Rasgrp4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
16605128 | J:108836
 
First Author: Stevens RL
Year: 2005
Journal: Novartis Found Symp
Title: RasGRP4 in mast cell signalling and disease susceptibility.
Volume: 271
Pages: 54-68; discussion 68-77, 95-9
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Publication
26982501 | J:301609
First Author: Zhou S
Year: 2016
Journal: PLoS One
Title: CD117+ Dendritic and Mast Cells Are Dependent on RasGRP4 to Function as Accessory Cells for Optimal Natural Killer Cell-Mediated Responses to Lipopolysaccharide.
Volume: 11
Issue: 3
Pages: e0151638
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Publication
11956218 | J:77824
First Author: Yang Y
Year: 2002
Journal: J Biol Chem
Title: RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function.
Volume: 277
Issue: 28
Pages: 25756-74
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Publication
22511759 | J:186519
First Author: Adachi R
Year: 2012
Journal: J Biol Chem
Title: Ras guanine nucleotide-releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis.
Volume: 287
Issue: 24
Pages: 20047-55
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Publication
22728827 | J:186412
First Author: Suire S
Year: 2012
Journal: EMBO J
Title: GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4.
Volume: 31
Issue: 14
Pages: 3118-29
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Publication
22262848 | J:299313
First Author: Zhu M
Year: 2012
Journal: J Biol Chem
Title: The role of Ras guanine nucleotide releasing protein 4 in Fc epsilonRI-mediated signaling, mast cell function, and T cell development.
Volume: 287
Issue: 11
Pages: 8135-43
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Publication
12817022 | J:84006
First Author: Li L
Year: 2003
Journal: J Immunol
Title: Mast cells in airway hyporesponsive C3H/HeJ mice express a unique isoform of the signaling protein Ras guanine nucleotide releasing protein 4 that is unresponsive to diacylglycerol and phorbol esters.
Volume: 171
Issue: 1
Pages: 390-7
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Publication
30720883 | J:280858
First Author: Suire S
Year: 2019
Journal: J Leukoc Biol
Title: Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses.
Volume: 106
Issue: 4
Pages: 815-822
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Protein Coding Gene
MGP_CAROLIEiJ_G0029472 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031971 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031949 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031881 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031675 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2386851 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032420 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031641 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031793 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031750 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031873 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031786 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032450 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030735 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031119 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012706 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030568 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
       
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2008-04-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3776289
Age: embryonic day 13.0
Specimen Label: E13
Specimen Num: 3
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GXD Expression
GXD Expression
       
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2008-04-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3776289
Age: embryonic day 17.0
Specimen Label: E17
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6111383
Age: postnatal
Specimen Label: Balb/c Mouse
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1613828
Stage: TS28
Assay Id: MGI:6111384
Age: postnatal week 8-12
Specimen Label: Peritoneal cells
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6111384
Age: postnatal week 8-12
Specimen Label: Heart
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6111384
Age: postnatal week 8-12
Specimen Label: Brain
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6111384
Age: postnatal week 8-12
Specimen Label: Spleen
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6111384
Age: postnatal week 8-12
Specimen Label: Lung
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6111384
Age: postnatal week 8-12
Specimen Label: Liver
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6111384
Age: postnatal week 8-12
Specimen Label: Sk. muscle
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6111384
Age: postnatal week 8-12
Specimen Label: Kidney
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6111384
Age: postnatal week 8-12
Specimen Label: Testis
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6111384
Age: embryonic day 7.0
Specimen Label: 7-day embryo
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6111384
Age: embryonic day 11.0
Specimen Label: 11-day embryo
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6111384
Age: embryonic day 15.0
Specimen Label: 15-day embryo
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:3776272
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:6111384
Age: embryonic day 17.0
Specimen Label: 17-day embryo
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
     
Probe: MGI:6111388
Assay Type: Western blot
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1613828
Stage: TS28
Assay Id: MGI:6111391
Age: postnatal
Specimen Label: Peritoneal cells
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6111388
Assay Type: Immunohistochemistry
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718528
Pattern: Single cells
Stage: TS28
Assay Id: MGI:6111389
Age: postnatal
Note: Expression is in mast cells.
Specimen Label: 3b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6111388
Assay Type: Immunohistochemistry
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1613828
Pattern: Single cells
Stage: TS28
Assay Id: MGI:6111389
Age: postnatal
Note: Expression is in mast cells.
Specimen Label: 3f
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6111388
Assay Type: Immunohistochemistry
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Pattern: Single cells
Stage: TS28
Assay Id: MGI:6111389
Age: postnatal
Note: Expression is in mast cells.
Specimen Label: 3d
Detected: true
Specimen Num: 2
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Publication
18172297 | J:131036
First Author: Ikuta S
Year: 2008
Journal: Cancer Res
Title: Crucial role of phospholipase C epsilon in skin inflammation induced by tumor-promoting phorbol ester.
Volume: 68
Issue: 1
Pages: 64-72
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Publication
24692514 | J:299344
First Author: Fischl AM
Year: 2014
Journal: Chem Senses
Title: Activity-dependent genes in mouse olfactory sensory neurons.
Volume: 39
Issue: 5
Pages: 439-49
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Rasgrp4<em1Smoc> | MGI:7291981
Name: RAS guanyl releasing protein 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
19727076 | J:152381
First Author: Lauchle JO
Year: 2009
Journal: Nature
Title: Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras.
Volume: 461
Issue: 7262
Pages: 411-4
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom