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Search results 1 to 93 out of 93 for Rassf3

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
283349 | RASSF3
Type: gene
Organism: human
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Gene
743444 | RASSF3
Type: gene
Organism: chimpanzee
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Gene
536808 | RASSF3
Type: gene
Organism: cattle
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Gene
417828 | RASSF3
Type: gene
Organism: chicken
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Gene
792539 | rassf3
Type: gene
Organism: zebrafish
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Gene
715339 | RASSF3
Type: gene
Organism: macaque, rhesus
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Gene
448113 | rassf3
Type: gene
Organism: frog, western clawed
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Gene
362886 | Rassf3
Type: gene
Organism: rat
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Gene
608312 | RASSF3
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:2179722 | Rassf3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR033619 | RASSF3
Type: Family
Description: The Ras association domain (RASSF) proteins are named due to the presence of a Ras association (RA) domain in their N or C terminus that can potentially interact with the Ras GTPase family of proteins. These GTPases control a variety of cellular processes, such as membrane trafficking,apoptosis, and proliferation. RASSF proteins contain several other functional domains that modulate associations with other proteins. RASSF proteins with the RA domain at the C terminus (which are termed C-terminal or classical RASSF) usually also include a Salvador-RASSF-Hippo (SARAH) domain involved in several protein-protein interactions and for homo- and heterodimerisation of RASSF isoforms. N-terminal RASSF proteins (with the RA domain in the N terminus) do not usually contain a SARAH domain [].At least 10 RASSF family members have been characterised (with multiple splice variants), many of which have been shown to play a role in tumour suppression. RASSF proteins also act as scaffolding agents in microtubule stability, regulate mitotic cell division, control cell migration and cell adhesion, and modulate NF-KB activity and the duration of inflammation. Loss of RASSF expression through promoter methylation has been shown in numerous types of cancer, including leukemia, melanoma, breast and prostate cancer [].RASSF3 is one of the C-terminal (also known as classical) RASSF proteins, characterised by an RA domain in the C terminus. It has been suggested to function as a tumour suppressor through stabilisation of p53, and resultant regulation of apoptosis [].
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Gene
105369804 | RASSF3-DT
Type: gene
Organism: human
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Publication
22593196 | -
First Author: Kudo T
Year: 2012
Journal: Cancer Res
Title: The RASSF3 candidate tumor suppressor induces apoptosis and G1-S cell-cycle arrest via p53.
Volume: 72
Issue: 11
Pages: 2901-11
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Publication
11965544 | J:76151
First Author: Tommasi S
Year: 2002
Journal: Oncogene
Title: RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1.
Volume: 21
Issue: 17
Pages: 2713-20
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Protein
Q99P51
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: false
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Publication
24607545 | J:212135
First Author: Volodko N
Year: 2014
Journal: FEBS Lett
Title: RASSF tumor suppressor gene family: biological functions and regulation.
Volume: 588
Issue: 16
Pages: 2671-84
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Publication
23357313 | -
First Author: Chan JJ
Year: 2013
Journal: Adv Biol Regul
Title: Comparative analysis of interactions of RASSF1-10.
Volume: 53
Issue: 2
Pages: 190-201
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Protein Coding Gene
MGP_CAROLIEiJ_G0015856 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017782 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017757 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017720 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017721 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017545 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2179722 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018176 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017514 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017620 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017615 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017694 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017644 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018216 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016890 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017166 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031230 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016681 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_01
Specimen Label: euxassay_002334_01
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_02
Specimen Label: euxassay_002334_02
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_03
Specimen Label: euxassay_002334_03
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_04
Specimen Label: euxassay_002334_04
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_05
Specimen Label: euxassay_002334_05
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_06
Specimen Label: euxassay_002334_06
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_07
Specimen Label: euxassay_002334_07
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_08
Specimen Label: euxassay_002334_08
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_10
Specimen Label: euxassay_002334_10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_11
Specimen Label: euxassay_002334_11
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_12
Specimen Label: euxassay_002334_12
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_13
Specimen Label: euxassay_002334_13
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_14
Specimen Label: euxassay_002334_14
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_15
Specimen Label: euxassay_002334_15
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_16
Specimen Label: euxassay_002334_16
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_17
Specimen Label: euxassay_002334_17
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_18
Specimen Label: euxassay_002334_18
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_19
Specimen Label: euxassay_002334_19
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_20
Specimen Label: euxassay_002334_20
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_21
Specimen Label: euxassay_002334_21
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_22
Specimen Label: euxassay_002334_22
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3596123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_23
Specimen Label: euxassay_002334_23
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1718523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_09
Specimen Label: euxassay_002334_09
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1718523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_10
Specimen Label: euxassay_002334_10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1718523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_11
Specimen Label: euxassay_002334_11
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1718523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_12
Specimen Label: euxassay_002334_12
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1718523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_13
Specimen Label: euxassay_002334_13
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:1054012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1718523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827634
Age: embryonic day 14.5
Image: euxassay_002334_14
Specimen Label: euxassay_002334_14
Detected: true
Specimen Num: 14
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Publication
- | J:76590
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, clone MGC: 19436 IMAGE: 3495833, mRNA, complete cds
Pages: BC011511
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
19148488 | J:156981
First Author: Jacquemart IC
Year: 2009
Journal: Int J Oncol
Title: Rassf3 is responsible in part for resistance to mammary tumor development in neu transgenic mice.
Volume: 34
Issue: 2
Pages: 517-28
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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