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Search results 1 to 100 out of 1321 for Rb1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Gonzalez-Vasconcellos I
Year: 2013
Journal: Cancer Res
Title: Rb1 haploinsufficiency promotes telomere attrition and radiation-induced genomic instability.
Volume: 73
Issue: 14
Pages: 4247-55
Publication
First Author: Hosoyama T
Year: 2011
Journal: J Biol Chem
Title: Rb1 gene inactivation expands satellite cell and postnatal myoblast pools.
Volume: 286
Issue: 22
Pages: 19556-64
Publication
First Author: Andreeva V
Year: 2012
Journal: Gene Expr Patterns
Title: Rb1 mRNA expression in developing mouse teeth.
Volume: 12
Issue: 3-4
Pages: 130-5
Publication
First Author: Sun H
Year: 2006
Journal: Mol Cell Biol
Title: An E2F binding-deficient Rb1 protein partially rescues developmental defects associated with Rb1 nullizygosity.
Volume: 26
Issue: 4
Pages: 1527-37
Publication
First Author: Jones RA
Year: 2016
Journal: J Clin Invest
Title: RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation.
Volume: 126
Issue: 10
Pages: 3739-3757
Publication
First Author: Zacksenhaus E
Year: 1993
Journal: Oncogene
Title: Molecular cloning and characterization of the mouse RB1 promoter.
Volume: 8
Issue: 9
Pages: 2343-51
Publication
First Author: Sun H
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: E2f binding-deficient Rb1 protein suppresses prostate tumor progression in vivo.
Volume: 108
Issue: 2
Pages: 704-9
Publication  
First Author: Gonzalez-Vasconcellos I
Year: 2017
Journal: Sci Rep
Title: The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression.
Volume: 7
Pages: 42056
Publication
First Author: Flesken-Nikitin A
Year: 2003
Journal: Cancer Res
Title: Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium.
Volume: 63
Issue: 13
Pages: 3459-63
Publication
First Author: Freytsis M
Year: 2018
Journal: PLoS One
Title: Conditional deletion of RB1 in the Tie2 lineage leads to aortic valve regurgitation.
Volume: 13
Issue: 1
Pages: e0190623
Publication
First Author: Liu Y
Year: 2009
Journal: Cell Stem Cell
Title: Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype.
Volume: 4
Issue: 4
Pages: 336-47
Publication
First Author: Donovan SL
Year: 2012
Journal: Mol Biol Cell
Title: Retinal horizontal cells lacking Rb1 sustain persistent DNA damage and survive as polyploid giant cells.
Volume: 23
Issue: 22
Pages: 4362-72
Publication
First Author: Chinnam M
Year: 2016
Journal: Mol Cell Biol
Title: Evaluating Effects of Hypomorphic Thoc1 Alleles on Embryonic Development in Rb1 Null Mice.
Volume: 36
Issue: 11
Pages: 1621-7
Publication
First Author: Watanabe R
Year: 2005
Journal: Virchows Arch
Title: Rb1cc1 is critical for myoblast differentiation through Rb1 regulation.
Volume: 447
Issue: 3
Pages: 643-8
Publication
First Author: Harlander S
Year: 2017
Journal: Nat Med
Title: Combined mutation in Vhl, Trp53 and Rb1 causes clear cell renal cell carcinoma in mice.
Volume: 23
Issue: 7
Pages: 869-877
Publication
First Author: Meuwissen R
Year: 2003
Journal: Cancer Cell
Title: Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model.
Volume: 4
Issue: 3
Pages: 181-9
Publication
First Author: Cochrane CR
Year: 2020
Journal: J Clin Invest
Title: Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling.
Volume: 130
Issue: 8
Pages: 4006-4018
Publication
First Author: Ku SY
Year: 2017
Journal: Science
Title: Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance.
Volume: 355
Issue: 6320
Pages: 78-83
Publication
First Author: Carreira S
Year: 2005
Journal: Nature
Title: Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression.
Volume: 433
Issue: 7027
Pages: 764-9
Publication
First Author: Kucherlapati MH
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.
Volume: 105
Issue: 40
Pages: 15493-8
Publication
First Author: Sutherland KD
Year: 2011
Journal: Cancer Cell
Title: Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.
Volume: 19
Issue: 6
Pages: 754-64
Publication
First Author: Xiao H
Year: 2010
Journal: Genesis
Title: Construction of a dual affinity tagged allele of the Rb1 tumor suppressor gene in the mouse.
Volume: 48
Issue: 2
Pages: 121-6
Publication  
First Author: Rosemann M
Year: 2014
Journal: Mol Cancer
Title: A Rb1 promoter variant with reduced activity contributes to osteosarcoma susceptibility in irradiated mice.
Volume: 13
Pages: 182
Publication
First Author: Loffler KA
Year: 2007
Journal: Oncogene
Title: Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice.
Volume: 26
Issue: 27
Pages: 4009-17
Publication
First Author: Tonks ID
Year: 2010
Journal: Neoplasia
Title: Dual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.
Volume: 12
Issue: 3
Pages: 235-43
Publication
First Author: Filtz EA
Year: 2015
Journal: PLoS One
Title: Rb1 and Pten Co-Deletion in Osteoblast Precursor Cells Causes Rapid Lipoma Formation in Mice.
Volume: 10
Issue: 8
Pages: e0136729
Publication
First Author: Pratt CH
Year: 2011
Journal: PLoS One
Title: Mitotic defects lead to pervasive aneuploidy and accompany loss of RB1 activity in mouse LmnaDhe dermal fibroblasts.
Volume: 6
Issue: 3
Pages: e18065
Publication
First Author: Lin W
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1.
Volume: 108
Issue: 33
Pages: 13379-86
Publication
First Author: Oser MG
Year: 2019
Journal: Cancer Discov
Title: Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival.
Volume: 9
Issue: 2
Pages: 230-247
Publication
First Author: Zhao H
Year: 2015
Journal: J Biol Chem
Title: Substituting threonine 187 with alanine in p27Kip1 prevents pituitary tumorigenesis by two-hit loss of Rb1 and enhances humoral immunity in old age.
Volume: 290
Issue: 9
Pages: 5797-809
Publication
First Author: El-Naggar S
Year: 2009
Journal: Mol Cell Biol
Title: Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation.
Volume: 29
Issue: 21
Pages: 5710-7
Publication
First Author: McBrayer SK
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase.
Volume: 115
Issue: 16
Pages: E3741-E3748
Publication
First Author: Zacksenhaus E
Year: 1996
Journal: Genes Dev
Title: pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis.
Volume: 10
Issue: 23
Pages: 3051-64
Publication
First Author: te Riele H
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs.
Volume: 89
Issue: 11
Pages: 5128-32
Publication
First Author: Xiao H
Year: 2005
Journal: Oncogene
Title: The retinoblastoma tumor suppressor protein is required for efficient processing and repair of trapped topoisomerase II-DNA-cleavable complexes.
Volume: 24
Issue: 55
Pages: 8105-13
Publication
First Author: Jiang Z
Year: 1997
Journal: Oncogene
Title: The retinoblastoma gene family is differentially expressed during embryogenesis.
Volume: 14
Issue: 15
Pages: 1789-97
Publication
First Author: Takahashi C
Year: 2006
Journal: Nat Genet
Title: Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor.
Volume: 38
Issue: 1
Pages: 118-23
Publication
First Author: Clarke AR
Year: 1992
Journal: Nature
Title: Requirement for a functional Rb-1 gene in murine development.
Volume: 359
Issue: 6393
Pages: 328-30
Publication
First Author: Ciavarra G
Year: 2010
Journal: J Cell Biol
Title: Rescue of myogenic defects in Rb-deficient cells by inhibition of autophagy or by hypoxia-induced glycolytic shift.
Volume: 191
Issue: 2
Pages: 291-301
Publication  
First Author: Costa C
Year: 2012
Journal: Sci Rep
Title: A novel tumor suppressor network in squamous malignancies.
Volume: 2
Pages: 828
Publication
First Author: Dooley AL
Year: 2011
Journal: Genes Dev
Title: Nuclear factor I/B is an oncogene in small cell lung cancer.
Volume: 25
Issue: 14
Pages: 1470-5
Publication
First Author: Williams BO
Year: 1994
Journal: EMBO J
Title: Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences.
Volume: 13
Issue: 18
Pages: 4251-9
Publication
First Author: Gutierrez GM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice.
Volume: 105
Issue: 47
Pages: 18402-7
Publication
First Author: Yang QE
Year: 2015
Journal: PLoS Genet
Title: Inactivation of Retinoblastoma Protein (Rb1) in the Oocyte: Evidence That Dysregulated Follicle Growth Drives Ovarian Teratoma Formation in Mice.
Volume: 11
Issue: 7
Pages: e1005355
Publication
First Author: Fu M
Year: 2013
Journal: J Clin Invest
Title: Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction.
Volume: 123
Issue: 12
Pages: 5152-64
Publication
First Author: Váraljai R
Year: 2015
Journal: Genes Dev
Title: Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells.
Volume: 29
Issue: 17
Pages: 1817-34
Publication
First Author: Xu XL
Year: 2017
Journal: Cancer Res
Title: SKP2 Activation by Thyroid Hormone Receptor β2 Bypasses Rb-Dependent Proliferation in Rb-Deficient Cells.
Volume: 77
Issue: 24
Pages: 6838-6850
Publication
First Author: Jacks T
Year: 1992
Journal: Nature
Title: Effects of an Rb mutation in the mouse.
Volume: 359
Issue: 6393
Pages: 295-300
Publication
First Author: Leung SW
Year: 2004
Journal: Oncogene
Title: A dynamic switch in Rb+/- mediated neuroendocrine tumorigenesis.
Volume: 23
Issue: 19
Pages: 3296-307
Publication
First Author: Petrov PD
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: Improved metabolic regulation is associated with retinoblastoma protein gene haploinsufficiency in mice.
Volume: 308
Issue: 2
Pages: E172-83
Publication
First Author: Choi YS
Year: 2005
Journal: Mech Ageing Dev
Title: Generation of reversible Rb-knockdown mice.
Volume: 126
Issue: 11
Pages: 1164-9
Publication
First Author: Clark AJ
Year: 2004
Journal: Blood
Title: Cell-intrinsic requirement for pRb in erythropoiesis.
Volume: 104
Issue: 5
Pages: 1324-6
Publication
First Author: Zhou Z
Year: 2005
Journal: Cancer Res
Title: Suppression of melanotroph carcinogenesis leads to accelerated progression of pituitary anterior lobe tumors and medullary thyroid carcinomas in Rb+/- mice.
Volume: 65
Issue: 3
Pages: 787-96
Publication
First Author: Seoane M
Year: 2017
Journal: Sci Rep
Title: Uncoupling Oncogene-Induced Senescence (OIS) and DNA Damage Response (DDR) triggered by DNA hyper-replication: lessons from primary mouse embryo astrocytes (MEA).
Volume: 7
Issue: 1
Pages: 12991
Publication
First Author: Bignon YJ
Year: 1993
Journal: Genes Dev
Title: Expression of a retinoblastoma transgene results in dwarf mice.
Volume: 7
Issue: 9
Pages: 1654-62
Publication
First Author: Wang Y
Year: 2000
Journal: Cancer Res
Title: Sex hormone-induced carcinogenesis in Rb-deficient prostate tissue.
Volume: 60
Issue: 21
Pages: 6008-17
Publication
First Author: Zhou C
Year: 2009
Journal: Mol Endocrinol
Title: E2F1 induces pituitary tumor transforming gene (PTTG1) expression in human pituitary tumors.
Volume: 23
Issue: 12
Pages: 2000-12
Publication
First Author: Yang H
Year: 2002
Journal: Mol Cell Biol
Title: Tumor suppression by a severely truncated species of retinoblastoma protein.
Volume: 22
Issue: 9
Pages: 3103-10
Publication
First Author: Donangelo I
Year: 2006
Journal: Endocrinology
Title: Pituitary tumor transforming gene overexpression facilitates pituitary tumor development.
Volume: 147
Issue: 10
Pages: 4781-91
Publication
First Author: Mercader J
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Haploinsufficiency of the retinoblastoma protein gene reduces diet-induced obesity, insulin resistance, and hepatosteatosis in mice.
Volume: 297
Issue: 1
Pages: E184-93
Publication
First Author: Sage C
Year: 2005
Journal: Science
Title: Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein.
Volume: 307
Issue: 5712
Pages: 1114-8
Publication
First Author: Zhang J
Year: 2004
Journal: Nat Genet
Title: Rb regulates proliferation and rod photoreceptor development in the mouse retina.
Volume: 36
Issue: 4
Pages: 351-60
Publication
First Author: Chow LM
Year: 2011
Journal: Cancer Cell
Title: Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain.
Volume: 19
Issue: 3
Pages: 305-16
Publication
First Author: Wang H
Year: 2010
Journal: Nat Genet
Title: Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice.
Volume: 42
Issue: 1
Pages: 83-8
Publication
First Author: Costa C
Year: 2013
Journal: Oncogene
Title: E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis.
Volume: 32
Issue: 24
Pages: 2937-51
Publication
First Author: Maandag EC
Year: 1994
Journal: EMBO J
Title: Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice.
Volume: 13
Issue: 18
Pages: 4260-8
Publication
First Author: Rubin BP
Year: 2011
Journal: Cancer Cell
Title: Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma.
Volume: 19
Issue: 2
Pages: 177-91
Publication
First Author: Tanaka T
Year: 2015
Journal: J Reprod Dev
Title: The CDKN1B-RB1-E2F1 pathway protects mouse spermatogonial stem cells from genomic damage.
Volume: 61
Issue: 4
Pages: 305-16
Publication
First Author: Chung PED
Year: 2020
Journal: Nat Commun
Title: Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy.
Volume: 11
Issue: 1
Pages: 1825
Publication  
First Author: Calbó J
Year: 2005
Journal: Cold Spring Harb Symp Quant Biol
Title: Genotype-phenotype relationships in a mouse model for human small-cell lung cancer.
Volume: 70
Pages: 225-32
Publication
First Author: He F
Year: 2009
Journal: Cancer Res
Title: Deficiency of pRb family proteins and p53 in invasive urothelial tumorigenesis.
Volume: 69
Issue: 24
Pages: 9413-21
Publication
First Author: Akaeda S
Year: 2021
Journal: EMBO Rep
Title: Retinoblastoma protein promotes uterine epithelial cell cycle arrest and necroptosis for embryo invasion.
Volume: 22
Issue: 2
Pages: e50927
Publication
First Author: Gündüz V
Year: 2012
Journal: Mol Cell Biol
Title: Loss of the retinoblastoma tumor suppressor protein in murine calvaria facilitates immortalization of osteoblast-adipocyte bipotent progenitor cells characterized by low expression of N-cadherin.
Volume: 32
Issue: 13
Pages: 2561-9
Publication
First Author: Wikenheiser-Brokamp KA
Year: 2004
Journal: Development
Title: Rb family proteins differentially regulate distinct cell lineages during epithelial development.
Volume: 131
Issue: 17
Pages: 4299-310
Publication
First Author: Yang QE
Year: 2013
Journal: Biol Reprod
Title: Retinoblastoma protein (RB1) controls fate determination in stem cells and progenitors of the mouse male germline.
Volume: 89
Issue: 5
Pages: 113
Publication
First Author: Serra R
Year: 1995
Journal: Development
Title: pRb is necessary for inhibition of N-myc expression by TGF-beta 1 in embryonic lung organ cultures.
Volume: 121
Issue: 9
Pages: 3057-66
Publication
First Author: Armstrong JF
Year: 1998
Journal: Br J Cancer
Title: Inbreeding abolishes the effect of parental origin of a mutant Rb-1 allele on pituitary tumorigenesis in mice.
Volume: 78
Issue: 4
Pages: 484-5
Publication
First Author: Kalitsis P
Year: 2005
Journal: Genes Chromosomes Cancer
Title: Increased chromosome instability but not cancer predisposition in haploinsufficient Bub3 mice.
Volume: 44
Issue: 1
Pages: 29-36
Publication
First Author: Zhao H
Year: 2020
Journal: Cancer Res
Title: Targeted Inhibition of the E3 Ligase SCFSkp2/Cks1 Has Antitumor Activity in RB1-Deficient Human and Mouse Small-Cell Lung Cancer.
Volume: 80
Issue: 11
Pages: 2355-2367
Publication
First Author: Weiss WA
Year: 1997
Journal: EMBO J
Title: Targeted expression of MYCN causes neuroblastoma in transgenic mice.
Volume: 16
Issue: 11
Pages: 2985-95
Publication
First Author: Novitch BG
Year: 1999
Journal: Curr Biol
Title: pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation.
Volume: 9
Issue: 9
Pages: 449-59
Publication
First Author: Takahashi C
Year: 2004
Journal: Mol Cell Biol
Title: Genetic interaction between Rb and K-ras in the control of differentiation and tumor suppression.
Volume: 24
Issue: 23
Pages: 10406-15
Publication
First Author: Kim YC
Year: 2011
Journal: EMBO J
Title: RB regulates pancreas development by stabilizing Pdx1.
Volume: 30
Issue: 8
Pages: 1563-76
Publication
First Author: Davis JN
Year: 2005
Journal: Cancer Res
Title: Disruption of Rb/E2F pathway results in increased cyclooxygenase-2 expression and activity in prostate epithelial cells.
Volume: 65
Issue: 9
Pages: 3633-42
Publication
First Author: Eason DD
Year: 2003
Journal: Oncogene
Title: Development of CD30+ lymphoproliferative disease in mice lacking interferon regulatory factor-1.
Volume: 22
Issue: 40
Pages: 6166-76
Publication
First Author: Kansara M
Year: 2013
Journal: J Clin Invest
Title: Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation.
Volume: 123
Issue: 12
Pages: 5351-60
Publication
First Author: Zhai Y
Year: 2017
Journal: J Pathol
Title: High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease.
Volume: 243
Issue: 1
Pages: 16-25
Publication
First Author: Zoumpoulidou G
Year: 2012
Journal: J Natl Cancer Inst
Title: Role of the tripartite motif protein 27 in cancer development.
Volume: 104
Issue: 12
Pages: 941-52
Publication
First Author: Guo Z
Year: 2001
Journal: Cancer Res
Title: Inactivation of the retinoblastoma tumor suppressor induces apoptosis protease-activating factor-1 dependent and independent apoptotic pathways during embryogenesis.
Volume: 61
Issue: 23
Pages: 8395-400
Publication
First Author: Zhao H
Year: 2016
Journal: J Biol Chem
Title: Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis.
Volume: 291
Issue: 19
Pages: 10201-9
Publication
First Author: Tracy K
Year: 2007
Journal: Mol Cell Biol
Title: BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.
Volume: 27
Issue: 17
Pages: 6229-42
Publication
First Author: Laurie NA
Year: 2006
Journal: Nature
Title: Inactivation of the p53 pathway in retinoblastoma.
Volume: 444
Issue: 7115
Pages: 61-6
Publication
First Author: Semenova EA
Year: 2016
Journal: Cell Rep
Title: Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients.
Volume: 16
Issue: 3
Pages: 631-43