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Search results 1 to 100 out of 422 for Rbl1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: This entry represents the retinoblastoma-like protein 1 (RBL1, also known as p107). Members of this family contain a conserved domain named the 'pocket' that interacts with the LXCXE motif found in viral proteins, such as SV40 large T antigen []. RBL1 is a component of the DREAM complex, which represses cell cycle-dependent genes in quiescent cells and plays a role in the cell cycle-dependent activation of G2/M genes [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein
Organism: Mus musculus
Length: 682  
Fragment?: true
Publication  
First Author: Dick FA
Year: 2007
Journal: Cell Div
Title: Structure-function analysis of the retinoblastoma tumor suppressor protein - is the whole a sum of its parts?
Volume: 2
Pages: 26
Protein
Organism: Mus musculus
Length: 817  
Fragment?: false
Protein
Organism: Mus musculus
Length: 594  
Fragment?: false
Publication
First Author: Litovchick L
Year: 2007
Journal: Mol Cell
Title: Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence.
Volume: 26
Issue: 4
Pages: 539-51
Publication
First Author: Schmit F
Year: 2007
Journal: Cell Cycle
Title: LINC, a human complex that is related to pRB-containing complexes in invertebrates regulates the expression of G2/M genes.
Volume: 6
Issue: 15
Pages: 1903-13
Protein
Organism: Mus musculus
Length: 1063  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1063  
Fragment?: false
Publication
First Author: Sindermann JR
Year: 2003
Journal: Am J Physiol Heart Circ Physiol
Title: Vascular ligation response is independent of p107: stressing the role of the related p130.
Volume: 285
Issue: 2
Pages: H915-8
Publication
First Author: Scimè A
Year: 2010
Journal: J Cell Biol
Title: Oxidative status of muscle is determined by p107 regulation of PGC-1alpha.
Volume: 190
Issue: 4
Pages: 651-62
Publication
First Author: LeCouter JE
Year: 1998
Journal: Mol Cell Biol
Title: Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene.
Volume: 18
Issue: 12
Pages: 7455-65
Publication  
First Author: Tarangelo A
Year: 2015
Journal: Nat Commun
Title: Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.
Volume: 6
Pages: 10028
Publication
First Author: Scimè A
Year: 2005
Journal: Cell Metab
Title: Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1alpha.
Volume: 2
Issue: 5
Pages: 283-95
Publication
First Author: Lara MF
Year: 2008
Journal: Mol Carcinog
Title: p107 acts as a tumor suppressor in pRb-deficient epidermis.
Volume: 47
Issue: 2
Pages: 105-13
Publication
First Author: Wu N
Year: 2017
Journal: J Clin Invest
Title: A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence.
Volume: 127
Issue: 3
Pages: 888-898
Publication
First Author: Vanderluit JL
Year: 2007
Journal: J Cell Biol
Title: The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate.
Volume: 178
Issue: 1
Pages: 129-39
Publication
First Author: Cobrinik D
Year: 1996
Journal: Genes Dev
Title: Shared role of the pRB-related p130 and p107 proteins in limb development.
Volume: 10
Issue: 13
Pages: 1633-44
Publication
First Author: Mulligan GJ
Year: 1998
Journal: Mol Cell Biol
Title: p130 is dispensable in peripheral T lymphocytes: evidence for functional compensation by p107 and pRB.
Volume: 18
Issue: 1
Pages: 206-20
Publication
First Author: Vanderluit JL
Year: 2004
Journal: J Cell Biol
Title: p107 regulates neural precursor cells in the mammalian brain.
Volume: 166
Issue: 6
Pages: 853-63
Publication
First Author: Robanus-Maandag E
Year: 1998
Journal: Genes Dev
Title: p107 is a suppressor of retinoblastoma development in pRb-deficient mice.
Volume: 12
Issue: 11
Pages: 1599-609
Publication
First Author: Viatour P
Year: 2008
Journal: Cell Stem Cell
Title: Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family.
Volume: 3
Issue: 4
Pages: 416-28
Publication
First Author: Yeh N
Year: 2007
Journal: Mol Cell Biol
Title: Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130.
Volume: 27
Issue: 14
Pages: 5161-71
Publication
First Author: Ruiz S
Year: 2004
Journal: Dev Dyn
Title: Functional link between retinoblastoma family of proteins and the Wnt signaling pathway in mouse epidermis.
Volume: 230
Issue: 3
Pages: 410-8
Publication
First Author: Santos M
Year: 2014
Journal: Cancer Res
Title: In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer.
Volume: 74
Issue: 22
Pages: 6565-6577
Publication
First Author: Lee MH
Year: 1996
Journal: Genes Dev
Title: Targeted disruption of p107: functional overlap between p107 and Rb.
Volume: 10
Issue: 13
Pages: 1621-32
Publication
First Author: Kim E
Year: 2017
Journal: J Exp Med
Title: Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression.
Volume: 214
Issue: 7
Pages: 1901-1912
Publication
First Author: Nair RM
Year: 2013
Journal: Saudi J Ophthalmol
Title: Animal models in retinoblastoma research.
Volume: 27
Issue: 3
Pages: 141-6
Publication
First Author: Dannenberg JH
Year: 2004
Journal: Genes Dev
Title: Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130.
Volume: 18
Issue: 23
Pages: 2952-62
Publication
First Author: Chen D
Year: 2004
Journal: Cancer Cell
Title: Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma.
Volume: 5
Issue: 6
Pages: 539-51
Publication
First Author: MacLean HE
Year: 2004
Journal: J Clin Invest
Title: The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes.
Volume: 113
Issue: 9
Pages: 1334-43
Publication
First Author: Wirt SE
Year: 2010
Journal: J Cell Biol
Title: G1 arrest and differentiation can occur independently of Rb family function.
Volume: 191
Issue: 4
Pages: 809-25
Publication
First Author: Rossi F
Year: 2002
Journal: Dev Biol
Title: p107 and p130 Coordinately regulate proliferation, Cbfa1 expression, and hypertrophic differentiation during endochondral bone development.
Volume: 247
Issue: 2
Pages: 271-85
Publication
First Author: Sangwan M
Year: 2012
Journal: Oncogene
Title: Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation.
Volume: 31
Issue: 48
Pages: 5019-28
Publication
First Author: Ruiz S
Year: 2003
Journal: Development
Title: Abnormal epidermal differentiation and impaired epithelial-mesenchymal tissue interactions in mice lacking the retinoblastoma relatives p107 and p130.
Volume: 130
Issue: 11
Pages: 2341-53
Publication
First Author: Brennan RC
Year: 2011
Journal: Cancer Res
Title: Targeting the p53 pathway in retinoblastoma with subconjunctival Nutlin-3a.
Volume: 71
Issue: 12
Pages: 4205-13
Publication
First Author: Laurie N
Year: 2009
Journal: Mol Cell Biol
Title: Changes in retinoblastoma cell adhesion associated with optic nerve invasion.
Volume: 29
Issue: 23
Pages: 6268-82
Publication
First Author: Simpson DS
Year: 2009
Journal: Cancer Res
Title: Retinoblastoma family proteins have distinct functions in pulmonary epithelial cells in vivo critical for suppressing cell growth and tumorigenesis.
Volume: 69
Issue: 22
Pages: 8733-41
Publication
First Author: Harrington EA
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: pRB plays an essential role in cell cycle arrest induced by DNA damage.
Volume: 95
Issue: 20
Pages: 11945-50
Publication
First Author: Garcia MA
Year: 2009
Journal: PLoS One
Title: Activation of NF-kB pathway by virus infection requires Rb expression.
Volume: 4
Issue: 7
Pages: e6422
Publication
First Author: Liu Y
Year: 2009
Journal: Cell Stem Cell
Title: Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype.
Volume: 4
Issue: 4
Pages: 336-47
Publication
First Author: Reed CA
Year: 2010
Journal: J Biol Chem
Title: Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control.
Volume: 285
Issue: 2
Pages: 1089-96
Publication
First Author: Hurford RK Jr
Year: 1997
Journal: Genes Dev
Title: pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.
Volume: 11
Issue: 11
Pages: 1447-63
Publication
First Author: Harb G
Year: 2009
Journal: Diabetes
Title: The retinoblastoma protein and its homolog p130 regulate the G1/S transition in pancreatic beta-cells.
Volume: 58
Issue: 8
Pages: 1852-62
Publication
First Author: Shin MK
Year: 2012
Journal: Cancer Res
Title: Inactivating all three rb family pocket proteins is insufficient to initiate cervical cancer.
Volume: 72
Issue: 20
Pages: 5418-27
Publication
First Author: Filtz EA
Year: 2015
Journal: PLoS One
Title: Rb1 and Pten Co-Deletion in Osteoblast Precursor Cells Causes Rapid Lipoma Formation in Mice.
Volume: 10
Issue: 8
Pages: e0136729
Publication
First Author: Benavente CA
Year: 2013
Journal: Oncotarget
Title: Cross-species genomic and epigenomic landscape of retinoblastoma.
Volume: 4
Issue: 6
Pages: 844-59
Publication
First Author: Wang Y
Year: 2007
Journal: Dev Biol
Title: The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression.
Volume: 311
Issue: 2
Pages: 478-86
Publication
First Author: MacPherson D
Year: 2007
Journal: EMBO J
Title: Murine bilateral retinoblastoma exhibiting rapid-onset, metastatic progression and N-myc gene amplification.
Volume: 26
Issue: 3
Pages: 784-94
Publication
First Author: Conkrite K
Year: 2012
Journal: J Clin Invest
Title: Cooperation between Rb and Arf in suppressing mouse retinoblastoma.
Volume: 122
Issue: 5
Pages: 1726-33
Publication
First Author: Viatour P
Year: 2011
Journal: J Exp Med
Title: Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.
Volume: 208
Issue: 10
Pages: 1963-76
Publication
First Author: Oshikawa M
Year: 2017
Journal: Development
Title: Dnmt1-dependent Chk1 pathway suppression is protective against neuron division.
Volume: 144
Issue: 18
Pages: 3303-3314
Publication
First Author: Garfin PM
Year: 2013
Journal: J Exp Med
Title: Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression.
Volume: 210
Issue: 6
Pages: 1087-97
Publication
First Author: García-Cao M
Year: 2002
Journal: Nat Genet
Title: A role for the Rb family of proteins in controlling telomere length.
Volume: 32
Issue: 3
Pages: 415-9
Publication
First Author: Johnson DA
Year: 2007
Journal: Cancer Res
Title: Neuronal differentiation and synaptogenesis in retinoblastoma.
Volume: 67
Issue: 6
Pages: 2701-11
Publication
First Author: Zhang J
Year: 2004
Journal: Cell Cycle
Title: The first knockout mouse model of retinoblastoma.
Volume: 3
Issue: 7
Pages: 952-9
Publication
First Author: Laurie NA
Year: 2006
Journal: Nature
Title: Inactivation of the p53 pathway in retinoblastoma.
Volume: 444
Issue: 7115
Pages: 61-6
Publication
First Author: Shin MK
Year: 2012
Journal: Cancer Res
Title: Pocket proteins suppress head and neck cancer.
Volume: 72
Issue: 5
Pages: 1280-9
Publication
First Author: Ajioka I
Year: 2007
Journal: Cell
Title: Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice.
Volume: 131
Issue: 2
Pages: 378-90
Publication
First Author: Lambertz I
Year: 2010
Journal: Cell Death Differ
Title: Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo.
Volume: 17
Issue: 4
Pages: 633-41
Publication
First Author: Oshikawa M
Year: 2013
Journal: Development
Title: Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner.
Volume: 140
Issue: 11
Pages: 2310-20
Publication
First Author: McClellan KA
Year: 2009
Journal: Mol Cell Biol
Title: The p107/E2F pathway regulates fibroblast growth factor 2 responsiveness in neural precursor cells.
Volume: 29
Issue: 17
Pages: 4701-13
Publication
First Author: Svoboda DS
Year: 2013
Journal: Dev Biol
Title: Pocket proteins pRb and p107 are required for cortical lamination independent of apoptosis.
Volume: 384
Issue: 1
Pages: 101-13
Publication
First Author: McEvoy J
Year: 2011
Journal: Cancer Cell
Title: Coexpression of normally incompatible developmental pathways in retinoblastoma genesis.
Volume: 20
Issue: 2
Pages: 260-75
Publication
First Author: Park JW
Year: 2014
Journal: Oncogene
Title: High incidence of female reproductive tract cancers in FA-deficient HPV16-transgenic mice correlates with E7's induction of DNA damage response, an activity mediated by E7's inactivation of pocket proteins.
Volume: 33
Issue: 26
Pages: 3383-91
Publication
First Author: Berman SD
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects.
Volume: 106
Issue: 35
Pages: 14932-6
Publication
First Author: Park DS
Year: 2013
Journal: Biol Open
Title: Pocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system.
Volume: 2
Issue: 9
Pages: 968-78
Publication
First Author: Chen D
Year: 2013
Journal: Cell Death Differ
Title: E2f2 induces cone photoreceptor apoptosis independent of E2f1 and E2f3.
Volume: 20
Issue: 7
Pages: 931-40
Publication
First Author: Walters BJ
Year: 2017
Journal: Cell Rep
Title: In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice.
Volume: 19
Issue: 2
Pages: 307-320
Publication
First Author: Nittner D
Year: 2012
Journal: Nat Cell Biol
Title: Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation.
Volume: 14
Issue: 9
Pages: 958-65
Publication
First Author: Landman AS
Year: 2013
Journal: Oncogene
Title: Loss of pRB and p107 disrupts cartilage development and promotes enchondroma formation.
Volume: 32
Issue: 40
Pages: 4798-805
Publication
First Author: Jiang Z
Year: 2010
Journal: J Clin Invest
Title: Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status.
Volume: 120
Issue: 9
Pages: 3296-309
Publication
First Author: Wikenheiser-Brokamp KA
Year: 2006
Journal: Cell Mol Life Sci
Title: Retinoblastoma family proteins: insights gained through genetic manipulation of mice.
Volume: 63
Issue: 7-8
Pages: 767-80
Publication
First Author: Ruiz S
Year: 2004
Journal: Development
Title: Unique and overlapping functions of pRb and p107 in the control of proliferation and differentiation in epidermis.
Volume: 131
Issue: 11
Pages: 2737-48
Publication
First Author: MacPherson D
Year: 2004
Journal: Genes Dev
Title: Cell type-specific effects of Rb deletion in the murine retina.
Volume: 18
Issue: 14
Pages: 1681-94
Publication
First Author: Conkrite K
Year: 2011
Journal: Genes Dev
Title: miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma.
Volume: 25
Issue: 16
Pages: 1734-45
Publication
First Author: Park JW
Year: 2013
Journal: PLoS One
Title: High incidence of HPV-associated head and neck cancers in FA deficient mice is associated with E7's induction of DNA damage through its inactivation of pocket proteins.
Volume: 8
Issue: 9
Pages: e75056
Publication
First Author: Lipinski MM
Year: 1999
Journal: Oncogene
Title: The retinoblastoma gene family in differentiation and development.
Volume: 18
Issue: 55
Pages: 7873-82
Publication  
First Author: Donovan SL
Year: 2006
Journal: BMC Biol
Title: Compensation by tumor suppressor genes during retinal development in mice and humans.
Volume: 4
Pages: 14
Publication
First Author: Spiller CM
Year: 2010
Journal: Biol Reprod
Title: Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice.
Volume: 82
Issue: 2
Pages: 433-43
Publication
First Author: Aldiri I
Year: 2015
Journal: Development
Title: Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma.
Volume: 142
Issue: 23
Pages: 4092-106
Publication
First Author: Ehmer U
Year: 2014
Journal: Cell Rep
Title: Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo.
Volume: 8
Issue: 2
Pages: 371-81
Publication
First Author: Chen H
Year: 2011
Journal: Nature
Title: PDGF signalling controls age-dependent proliferation in pancreatic β-cells.
Volume: 478
Issue: 7369
Pages: 349-55
Publication
First Author: Marino S
Year: 2003
Journal: Development
Title: Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence.
Volume: 130
Issue: 15
Pages: 3359-68
Publication
First Author: Vooijs M
Year: 2002
Journal: Oncogene
Title: Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells.
Volume: 21
Issue: 30
Pages: 4635-45
Publication
First Author: Kratochvill F
Year: 2015
Journal: Cell Rep
Title: TNF Counterbalances the Emergence of M2 Tumor Macrophages.
Volume: 12
Issue: 11
Pages: 1902-14
Publication
First Author: Chen D
Year: 2007
Journal: PLoS Biol
Title: Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a.
Volume: 5
Issue: 7
Pages: e179
Publication
First Author: Remy E
Year: 2015
Journal: Cancer Res
Title: A Modeling Approach to Explain Mutually Exclusive and Co-Occurring Genetic Alterations in Bladder Tumorigenesis.
Volume: 75
Issue: 19
Pages: 4042-52
Publication
First Author: Kobayashi T
Year: 2015
Journal: Nat Rev Cancer
Title: Modelling bladder cancer in mice: opportunities and challenges.
Volume: 15
Issue: 1
Pages: 42-54
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus