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Search results 1 to 100 out of 167 for Rd3

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: In humans, Retinal degeneration protein 3 (RD3) is found preferentially expressed in the retina []. Mutations in RD3 causes Leber Congenital Amaurosis type 12 ,which is a severe dystrophy of the retina, typically becoming evident in the first years of life [].
Publication
First Author: Friedman JS
Year: 2006
Journal: Am J Hum Genet
Title: Premature truncation of a novel protein, RD3, exhibiting subnuclear localization is associated with retinal degeneration.
Volume: 79
Issue: 6
Pages: 1059-70
Gene
Type: gene
Organism: human
Publication
First Author: Lavorgna G
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Identification and characterization of C1orf36, a transcript highly expressed in photoreceptor cells, and mutation analysis in retinitis pigmentosa.
Volume: 308
Issue: 3
Pages: 414-21
Protein
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: false
Publication  
First Author: Cheng CL
Year: 2013
Journal: Mol Vis
Title: Changes in gene expression associated with retinal degeneration in the rd3 mouse.
Volume: 19
Pages: 955-69
Publication
First Author: Peshenko IV
Year: 2016
Journal: J Biol Chem
Title: Functional Study and Mapping Sites for Interaction with the Target Enzyme in Retinal Degeneration 3 (RD3) Protein.
Volume: 291
Issue: 37
Pages: 19713-23
Publication
First Author: Molday LL
Year: 2013
Journal: Hum Mol Genet
Title: RD3 gene delivery restores guanylate cyclase localization and rescues photoreceptors in the Rd3 mouse model of Leber congenital amaurosis 12.
Volume: 22
Issue: 19
Pages: 3894-905
Publication
First Author: Danciger M
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Genetic modifiers of retinal degeneration in the rd3 mouse.
Volume: 49
Issue: 7
Pages: 2863-9
Publication
First Author: Chang B
Year: 1993
Journal: Genomics
Title: New mouse primary retinal degeneration (rd-3).
Volume: 16
Issue: 1
Pages: 45-9
Publication
First Author: Azadi S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: RD3, the protein associated with Leber congenital amaurosis type 12, is required for guanylate cyclase trafficking in photoreceptor cells.
Volume: 107
Issue: 49
Pages: 21158-63
Publication
First Author: Danciger JS
Year: 1999
Journal: Mamm Genome
Title: Genetic and physical maps of the mouse rd3 locus; exclusion of the ortholog of USH2A.
Volume: 10
Issue: 7
Pages: 657-61
Publication
First Author: Plana-Bonamaisó A
Year: 2020
Journal: Cell Death Dis
Title: GCAP neuronal calcium sensor proteins mediate photoreceptor cell death in the rd3 mouse model of LCA12 congenital blindness by involving endoplasmic reticulum stress.
Volume: 11
Issue: 1
Pages: 62
Publication  
First Author: Wimberg H
Year: 2018
Journal: Front Mol Neurosci
Title: Control of the Nucleotide Cycle in Photoreceptor Cell Extracts by Retinal Degeneration Protein 3.
Volume: 11
Pages: 52
Protein
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 132  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false
Publication
First Author: Dizhoor AM
Year: 2019
Journal: J Biol Chem
Title: Retinal guanylyl cyclase activation by calcium sensor proteins mediates photoreceptor degeneration in an rd3 mouse model of congenital human blindness.
Volume: 294
Issue: 37
Pages: 13729-13739
Publication
First Author: Pieke-Dahl S
Year: 1997
Journal: Hear Res
Title: Hearing loss in the RBF/DnJ mouse, a proposed animal model of Usher syndrome type IIa.
Volume: 112
Issue: 1-2
Pages: 1-12
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Publication    
First Author: Dizhoor AM
Year: 2021
Journal: J Biol Chem
Title: Retinal degeneration-3 protein promotes photoreceptor survival by suppressing activation of guanylyl cyclase rather than accelerating GMP recycling.
Pages: 100362
Publication
First Author: Tomarev SI
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Characterization of the mouse Prox1 gene.
Volume: 248
Issue: 3
Pages: 684-9
Publication
First Author: Inoue S
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains.
Volume: 268
Issue: 2
Pages: 553-61
Publication
First Author: Zulliger R
Year: 2015
Journal: J Biol Chem
Title: Impaired association of retinal degeneration-3 with guanylate cyclase-1 and guanylate cyclase-activating protein-1 leads to leber congenital amaurosis-1.
Volume: 290
Issue: 6
Pages: 3488-99
Publication  
First Author: Chen Y
Year: 2022
Journal: Front Mol Neurosci
Title: Retinal degeneration protein 3 controls membrane guanylate cyclase activities in brain tissue.
Volume: 15
Pages: 1076430
UniProt Feature
Begin: 1
Description: Protein RD3
Type: chain
End: 195
Publication
First Author: Heckenlively JR
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Mouse model for Usher syndrome: linkage mapping suggests homology to Usher type I reported at human chromosome 11p15.
Volume: 92
Issue: 24
Pages: 11100-4
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_07
Specimen Label: euxassay_007914_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_08
Specimen Label: euxassay_007914_08
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_09
Specimen Label: euxassay_007914_09
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_10
Specimen Label: euxassay_007914_10
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_11
Specimen Label: euxassay_007914_11
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_12
Specimen Label: euxassay_007914_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_13
Specimen Label: euxassay_007914_13
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_14
Specimen Label: euxassay_007914_14
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_15
Specimen Label: euxassay_007914_15
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_16
Specimen Label: euxassay_007914_16
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_17
Specimen Label: euxassay_007914_17
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:3584588
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585293
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3584588
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647028
Stage: TS28
Assay Id: MGI:3585293
Age: postnatal day 6
Specimen Label: CNS
Detected: false
Specimen Num: 5
GXD Expression
Probe: MGI:3584588
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585293
Age: postnatal day 2-3
Image: P2/3
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3584588
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585293
Age: postnatal day 4-5
Image: P4/5
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3584588
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585293
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3584588
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585293
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_03
Specimen Label: euxassay_007914_03
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_04
Specimen Label: euxassay_007914_04
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_05
Specimen Label: euxassay_007914_05
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_06
Specimen Label: euxassay_007914_06
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_07
Specimen Label: euxassay_007914_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_08
Specimen Label: euxassay_007914_08
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_09
Specimen Label: euxassay_007914_09
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_10
Specimen Label: euxassay_007914_10
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_11
Specimen Label: euxassay_007914_11
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_12
Specimen Label: euxassay_007914_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_13
Specimen Label: euxassay_007914_13
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_14
Specimen Label: euxassay_007914_14
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_15
Specimen Label: euxassay_007914_15
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_16
Specimen Label: euxassay_007914_16
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_17
Specimen Label: euxassay_007914_17
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_18
Specimen Label: euxassay_007914_18
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_19
Specimen Label: euxassay_007914_19
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4422756
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827672
Age: embryonic day 14.5
Image: euxassay_007914_20
Specimen Label: euxassay_007914_20
Detected: true
Specimen Num: 18