Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Boekhout M |
Year: |
2019 |
Journal: |
Mol Cell |
Title: |
REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks. |
Volume: |
74 |
Issue: |
5 |
Pages: |
1053-1068.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar R |
Year: |
2018 |
Journal: |
Life Sci Alliance |
Title: |
Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4. |
Volume: |
1 |
Issue: |
6 |
Pages: |
e201800259 |
|
•
•
•
•
•
|
Publication |
First Author: |
Papanikos F |
Year: |
2019 |
Journal: |
Mol Cell |
Title: |
Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes. |
Volume: |
74 |
Issue: |
5 |
Pages: |
1069-1085.e11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar R |
Year: |
2010 |
Journal: |
Genes Dev |
Title: |
Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice. |
Volume: |
24 |
Issue: |
12 |
Pages: |
1266-80 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3703337 |
Assay Type: |
RT-PCR |
Annotation Date: |
2007-04-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160415 |
|
Stage: |
TS05 |
Assay Id: |
MGI:3703365 |
Age: |
embryonic day 4.5 |
Image: |
5 |
|
Specimen Label: |
-/-, 4.5dpc |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3703337 |
Assay Type: |
RT-PCR |
Annotation Date: |
2007-04-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160414 |
|
Stage: |
TS04 |
Assay Id: |
MGI:3703365 |
Age: |
embryonic day 3.5 |
Image: |
5 |
|
Specimen Label: |
+/?, 3.5dpc |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6370151 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-11-08 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796220 |
|
Stage: |
TS20 |
Assay Id: |
MGI:6370156 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
E12 ovary |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6370151 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-11-08 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796225 |
|
Stage: |
TS25 |
Assay Id: |
MGI:6370156 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
E17 ovary |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6370151 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-11-08 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6370156 |
Age: |
postnatal day 5 |
|
|
Specimen Label: |
D5 ovary |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6370151 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-11-08 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3570528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6370156 |
Age: |
postnatal day 25 |
|
|
Specimen Label: |
25dpp GV |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3703337 |
Assay Type: |
RT-PCR |
Annotation Date: |
2007-04-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160414 |
|
Stage: |
TS04 |
Assay Id: |
MGI:3703365 |
Age: |
embryonic day 3.5 |
Image: |
5 |
|
Specimen Label: |
-/-, 3.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3703337 |
Assay Type: |
RT-PCR |
Annotation Date: |
2007-04-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160415 |
|
Stage: |
TS05 |
Assay Id: |
MGI:3703365 |
Age: |
embryonic day 4.5 |
Image: |
5 |
|
Specimen Label: |
+/?, 4.5dpc |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6370151 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-11-08 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796227 |
|
Stage: |
TS27 |
Assay Id: |
MGI:6370156 |
Age: |
postnatal newborn |
|
|
Specimen Label: |
NB ovary |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6370151 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-11-08 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3575528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6370156 |
Age: |
postnatal day 25 |
|
|
Specimen Label: |
25dpp MII |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stanzione M |
Year: |
2016 |
Journal: |
Nat Cell Biol |
Title: |
Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice. |
Volume: |
18 |
Issue: |
11 |
Pages: |
1208-1220 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu J |
Year: |
2023 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Essential roles of the ANKRD31-REC114 interaction in meiotic recombination and mouse spermatogenesis. |
Volume: |
120 |
Issue: |
47 |
Pages: |
e2310951120 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nore A |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
TOPOVIBL-REC114 interaction regulates meiotic DNA double-strand breaks. |
Volume: |
13 |
Issue: |
1 |
Pages: |
7048 |
|
•
•
•
•
•
|
Publication |
First Author: |
Malone RE |
Year: |
1997 |
Journal: |
Mol Gen Genet |
Title: |
Examination of the intron in the meiosis-specific recombination gene REC114 in Saccharomyces. |
Volume: |
255 |
Issue: |
4 |
Pages: |
410-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nguyen NMP |
Year: |
2018 |
Journal: |
Am J Hum Genet |
Title: |
Causative Mutations and Mechanism of Androgenetic Hydatidiform Moles. |
Volume: |
103 |
Issue: |
5 |
Pages: |
740-751 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bishop DK |
Year: |
1999 |
Journal: |
Genes Cells |
Title: |
High copy number suppression of the meiotic arrest caused by a dmc1 mutation: REC114 imposes an early recombination block and RAD54 promotes a DMC1-independent DSB repair pathway. |
Volume: |
4 |
Issue: |
8 |
Pages: |
425-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sabik OL |
Year: |
2017 |
Journal: |
G3 (Bethesda) |
Title: |
Genetic Dissection of a QTL Affecting Bone Geometry. |
Volume: |
7 |
Issue: |
3 |
Pages: |
865-870 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guan Y |
Year: |
2022 |
Journal: |
Nucleic Acids Res |
Title: |
SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. |
Volume: |
50 |
Issue: |
9 |
Pages: |
5129-5144 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaji K |
Year: |
2007 |
Journal: |
Development |
Title: |
Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. |
Volume: |
134 |
Issue: |
6 |
Pages: |
1123-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
Journal: |
Database Download |
Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Function or Process or Component Unknown following Literature Review |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Pittman D |
Year: |
1993 |
Journal: |
Curr Genet |
Title: |
Genetic and molecular analysis of REC114, an early meiotic recombination gene in yeast. |
Volume: |
23 |
Issue: |
4 |
Pages: |
295-304 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin Y |
Year: |
1992 |
Journal: |
Genetics |
Title: |
Meiotically induced rec7 and rec8 genes of Schizosaccharomyces pombe. |
Volume: |
132 |
Issue: |
1 |
Pages: |
75-85 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry includes budding yeast Rec114 protein and its homologue, Rec7, from S. pombe. They are required for meiotic intragenic recombination but not for mitotic recombination [, ]. REC114 is one of 10 genes required for initiation of meiotic recombination in Saccharomyces cerevisiae []. Located on chromosome XIII, it is transcribed only in meiosis and has no detectable function in mitosis []. REC114 has been shown to possess an intron and is one of only three genes in yeast with 3' introns []. The 3' splice site utilised in REC114 is a very rare AAG sequence - only three other genes in yeast use this non-consensus sequence []. It appears that the intron is not essential for expression of REC114 and is not absolutely required for meiotic function. Nevertheless, it is conserved in evolution - two other species of yeast contain an intron at the same location in their REC114 genes []. |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Meiotic recombination protein REC114 |
Type: |
chain |
End: |
259 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
259
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
11
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
119
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Allele |
Name: |
REC114 meiotic recombination protein; wild type |
Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
Allele |
Name: |
REC114 meiotic recombination protein; gene trap OST199612, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
REC114 meiotic recombination protein; gene trap OST232024, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
REC114 meiotic recombination protein; targeted mutation 1, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
REC114 meiotic recombination protein; targeted mutation 1.2, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2006 |
Journal: |
Genetics |
Title: |
Saccharomyces cerevisiae Mer2, Mei4 and Rec114 form a complex required for meiotic double-strand break formation. |
Volume: |
173 |
Issue: |
4 |
Pages: |
1969-81 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rec114/Rec114 |
Background: |
involves: C57BL/6N |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rec114/Rec114 |
Background: |
involves: C57BL/6N |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
|
•
•
•
•
•
|