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Search results 1 to 95 out of 95 for Rec114

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Boekhout M
Year: 2019
Journal: Mol Cell
Title: REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks.
Volume: 74
Issue: 5
Pages: 1053-1068.e8
Publication
First Author: Kumar R
Year: 2018
Journal: Life Sci Alliance
Title: Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4.
Volume: 1
Issue: 6
Pages: e201800259
Publication
First Author: Papanikos F
Year: 2019
Journal: Mol Cell
Title: Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes.
Volume: 74
Issue: 5
Pages: 1069-1085.e11
Publication
First Author: Kumar R
Year: 2010
Journal: Genes Dev
Title: Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice.
Volume: 24
Issue: 12
Pages: 1266-80
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:3703337
Assay Type: RT-PCR
Annotation Date: 2007-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Stage: TS04
Assay Id: MGI:3703365
Age: embryonic day 3.5
Image: 5
Specimen Label: -/-, 3.5dpc
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3703337
Assay Type: RT-PCR
Annotation Date: 2007-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3703365
Age: embryonic day 4.5
Image: 5
Specimen Label: -/-, 4.5dpc
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3703337
Assay Type: RT-PCR
Annotation Date: 2007-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3703365
Age: embryonic day 4.5
Image: 5
Specimen Label: +/?, 4.5dpc
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6370151
Assay Type: RT-PCR
Annotation Date: 2019-11-08
Strength: Present
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:6370156
Age: embryonic day 12.5
Specimen Label: E12 ovary
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6370151
Assay Type: RT-PCR
Annotation Date: 2019-11-08
Strength: Present
Sex: Female
Emaps: EMAPS:1796227
Stage: TS27
Assay Id: MGI:6370156
Age: postnatal newborn
Specimen Label: NB ovary
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6370151
Assay Type: RT-PCR
Annotation Date: 2019-11-08
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:6370156
Age: postnatal day 5
Specimen Label: D5 ovary
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6370151
Assay Type: RT-PCR
Annotation Date: 2019-11-08
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:6370156
Age: postnatal day 25
Specimen Label: 25dpp MII
Detected: true
Specimen Num: 6
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
GXD Expression    
Probe: MGI:3703337
Assay Type: RT-PCR
Annotation Date: 2007-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Stage: TS04
Assay Id: MGI:3703365
Age: embryonic day 3.5
Image: 5
Specimen Label: +/?, 3.5dpc
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6370151
Assay Type: RT-PCR
Annotation Date: 2019-11-08
Strength: Present
Sex: Female
Emaps: EMAPS:1796225
Stage: TS25
Assay Id: MGI:6370156
Age: embryonic day 17.5
Specimen Label: E17 ovary
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6370151
Assay Type: RT-PCR
Annotation Date: 2019-11-08
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:6370156
Age: postnatal day 25
Specimen Label: 25dpp GV
Detected: true
Specimen Num: 5
Publication
First Author: Stanzione M
Year: 2016
Journal: Nat Cell Biol
Title: Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice.
Volume: 18
Issue: 11
Pages: 1208-1220
Publication
First Author: Xu J
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Essential roles of the ANKRD31-REC114 interaction in meiotic recombination and mouse spermatogenesis.
Volume: 120
Issue: 47
Pages: e2310951120
Publication
First Author: Nore A
Year: 2022
Journal: Nat Commun
Title: TOPOVIBL-REC114 interaction regulates meiotic DNA double-strand breaks.
Volume: 13
Issue: 1
Pages: 7048
Publication
First Author: Malone RE
Year: 1997
Journal: Mol Gen Genet
Title: Examination of the intron in the meiosis-specific recombination gene REC114 in Saccharomyces.
Volume: 255
Issue: 4
Pages: 410-9
Publication
First Author: Nguyen NMP
Year: 2018
Journal: Am J Hum Genet
Title: Causative Mutations and Mechanism of Androgenetic Hydatidiform Moles.
Volume: 103
Issue: 5
Pages: 740-751
Publication
First Author: Bishop DK
Year: 1999
Journal: Genes Cells
Title: High copy number suppression of the meiotic arrest caused by a dmc1 mutation: REC114 imposes an early recombination block and RAD54 promotes a DMC1-independent DSB repair pathway.
Volume: 4
Issue: 8
Pages: 425-44
Publication
First Author: Sabik OL
Year: 2017
Journal: G3 (Bethesda)
Title: Genetic Dissection of a QTL Affecting Bone Geometry.
Volume: 7
Issue: 3
Pages: 865-870
Publication
First Author: Kaji K
Year: 2007
Journal: Development
Title: Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.
Volume: 134
Issue: 6
Pages: 1123-32
Publication
First Author: Guan Y
Year: 2022
Journal: Nucleic Acids Res
Title: SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination.
Volume: 50
Issue: 9
Pages: 5129-5144
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication
First Author: Pittman D
Year: 1993
Journal: Curr Genet
Title: Genetic and molecular analysis of REC114, an early meiotic recombination gene in yeast.
Volume: 23
Issue: 4
Pages: 295-304
Publication
First Author: Lin Y
Year: 1992
Journal: Genetics
Title: Meiotically induced rec7 and rec8 genes of Schizosaccharomyces pombe.
Volume: 132
Issue: 1
Pages: 75-85
Protein Domain
Type: Family
Description: This entry includes budding yeast Rec114 protein and its homologue, Rec7, from S. pombe. They are required for meiotic intragenic recombination but not for mitotic recombination [, ]. REC114 is one of 10 genes required for initiation of meiotic recombination in Saccharomyces cerevisiae []. Located on chromosome XIII, it is transcribed only in meiosis and has no detectable function in mitosis []. REC114 has been shown to possess an intron and is one of only three genes in yeast with 3' introns []. The 3' splice site utilised in REC114 is a very rare AAG sequence - only three other genes in yeast use this non-consensus sequence []. It appears that the intron is not essential for expression of REC114 and is not absolutely required for meiotic function. Nevertheless, it is conserved in evolution - two other species of yeast contain an intron at the same location in their REC114 genes [].
UniProt Feature
Begin: 1
Description: Meiotic recombination protein REC114
Type: chain
End: 259
Protein
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 11  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
Allele  
Name: REC114 meiotic recombination protein; wild type
Allele Type: Not Specified
Allele  
Name: REC114 meiotic recombination protein; gene trap OST232024, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: REC114 meiotic recombination protein; gene trap OST199612, Lexicon Genetics
Allele Type: Gene trapped
Allele
Name: REC114 meiotic recombination protein; targeted mutation 1.2, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: REC114 meiotic recombination protein; targeted mutation 1, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Publication
First Author: Li J
Year: 2006
Journal: Genetics
Title: Saccharomyces cerevisiae Mer2, Mei4 and Rec114 form a complex required for meiotic double-strand break formation.
Volume: 173
Issue: 4
Pages: 1969-81
Genotype
Symbol: Rec114/Rec114
Background: involves: C57BL/6N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Rec114/Rec114
Background: involves: C57BL/6N
Zygosity: hm
Has Mutant Allele: true
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112