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Search results 1 to 100 out of 20164 for Rest

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Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: The Repressor Element-1 (RE-1) Silencing Transcription (REST) factor is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells [, ]. REST is involved in neural differentiation and in preservation of the neural phenotype. REST also plays a role in proliferation, although its effect differs depending on the cell type [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chong JA
Year: 1995
Journal: Cell
Title: REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons.
Volume: 80
Issue: 6
Pages: 949-57
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Ballas N
Year: 2005
Journal: Cell
Title: REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.
Volume: 121
Issue: 4
Pages: 645-57
Publication
First Author: Ravanpay AC
Year: 2010
Journal: Mol Cell Neurosci
Title: Transcriptional inhibition of REST by NeuroD2 during neuronal differentiation.
Volume: 44
Issue: 2
Pages: 178-89
Publication
First Author: van der Rest M
Year: 1991
Journal: FASEB J
Title: Collagen family of proteins.
Volume: 5
Issue: 13
Pages: 2814-23
Publication
First Author: Negrini S
Year: 2013
Journal: Trends Cell Biol
Title: REST: an oncogene or a tumor suppressor?
Volume: 23
Issue: 6
Pages: 289-95
Publication
First Author: Lunyak VV
Year: 2002
Journal: Science
Title: Corepressor-dependent silencing of chromosomal regions encoding neuronal genes.
Volume: 298
Issue: 5599
Pages: 1747-52
Publication
First Author: Buckley NJ
Year: 2009
Journal: Nature
Title: Is REST a regulator of pluripotency?
Volume: 457
Issue: 7233
Pages: E5-6; discussion E7
Publication
First Author: Jørgensen HF
Year: 2009
Journal: Nature
Title: Is REST required for ESC pluripotency?
Volume: 457
Issue: 7233
Pages: E4-5; discussion E7
Protein
Organism: Mus musculus/domesticus
Length: 1082  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 328  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 522  
Fragment?: true
Publication
First Author: Lee M
Year: 2014
Journal: J Cell Sci
Title: p120-catenin regulates REST and CoREST, and modulates mouse embryonic stem cell differentiation.
Volume: 127
Issue: Pt 18
Pages: 4037-51
Publication
First Author: Monaghan CE
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain.
Volume: 114
Issue: 3
Pages: E406-E415
Publication
First Author: Lu T
Year: 2014
Journal: Nature
Title: REST and stress resistance in ageing and Alzheimer's disease.
Volume: 507
Issue: 7493
Pages: 448-54
Publication
First Author: Singh SK
Year: 2008
Journal: Nature
Title: REST maintains self-renewal and pluripotency of embryonic stem cells.
Volume: 453
Issue: 7192
Pages: 223-7
Publication
First Author: Nakano Y
Year: 2018
Journal: Cell
Title: Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness.
Volume: 174
Issue: 3
Pages: 536-548.e21
Publication  
First Author: Mukherjee S
Year: 2016
Journal: Nat Commun
Title: REST regulation of gene networks in adult neural stem cells.
Volume: 7
Pages: 13360
Publication
First Author: Westbrook TF
Year: 2008
Journal: Nature
Title: SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation.
Volume: 452
Issue: 7185
Pages: 370-4
Publication
First Author: Singh SK
Year: 2012
Journal: PLoS One
Title: Dynamic status of REST in the mouse ESC pluripotency network.
Volume: 7
Issue: 8
Pages: e43659
Publication
First Author: Zhang D
Year: 2017
Journal: Nat Commun
Title: REST regulates the cell cycle for cardiac development and regeneration.
Volume: 8
Issue: 1
Pages: 1979
Publication
First Author: Martin D
Year: 2015
Journal: Dev Biol
Title: REST represses a subset of the pancreatic endocrine differentiation program.
Volume: 405
Issue: 2
Pages: 316-27
Publication  
First Author: Nechiporuk T
Year: 2016
Journal: Elife
Title: The REST remodeling complex protects genomic integrity during embryonic neurogenesis.
Volume: 5
Pages: e09584
Publication
First Author: Conaco C
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Reciprocal actions of REST and a microRNA promote neuronal identity.
Volume: 103
Issue: 7
Pages: 2422-7
Publication
First Author: Grimes JA
Year: 2000
Journal: J Biol Chem
Title: The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex.
Volume: 275
Issue: 13
Pages: 9461-7
Publication
First Author: Kohyama J
Year: 2010
Journal: J Cell Biol
Title: BMP-induced REST regulates the establishment and maintenance of astrocytic identity.
Volume: 189
Issue: 1
Pages: 159-70
Publication
First Author: Johnson R
Year: 2008
Journal: PLoS Biol
Title: REST regulates distinct transcriptional networks in embryonic and neural stem cells.
Volume: 6
Issue: 10
Pages: e256
Publication
First Author: Tint GS
Year: 2014
Journal: Dev Neurosci
Title: Desmosterol in brain is elevated because DHCR24 needs REST for Robust Expression but REST is poorly expressed.
Volume: 36
Issue: 2
Pages: 132-42
Publication
First Author: Bersten DC
Year: 2014
Journal: Biochim Biophys Acta
Title: Regulation of the neuronal transcription factor NPAS4 by REST and microRNAs.
Volume: 1839
Issue: 1
Pages: 13-24
Publication
First Author: Rovira M
Year: 2021
Journal: Genes Dev
Title: REST is a major negative regulator of endocrine differentiation during pancreas organogenesis.
Volume: 35
Issue: 17-18
Pages: 1229-1242
Publication
First Author: Okamura D
Year: 2012
Journal: Dev Biol
Title: REST and its downstream molecule Mek5 regulate survival of primordial germ cells.
Volume: 372
Issue: 2
Pages: 190-202
Publication
First Author: Sun YM
Year: 2005
Journal: Mol Biol Cell
Title: Distinct profiles of REST interactions with its target genes at different stages of neuronal development.
Volume: 16
Issue: 12
Pages: 5630-8
DO Term
Publication
First Author: Aoki H
Year: 2021
Journal: Genes Cells
Title: Induced genetic ablation of Rest leads to the alteration of stimulus-induced response of the vagal nerve.
Volume: 26
Issue: 2
Pages: 45-55
Publication
First Author: Masserdotti G
Year: 2015
Journal: Cell Stem Cell
Title: Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes.
Volume: 17
Issue: 1
Pages: 74-88
Publication
First Author: Nesti E
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: C-terminal domain small phosphatase 1 and MAP kinase reciprocally control REST stability and neuronal differentiation.
Volume: 111
Issue: 37
Pages: E3929-36
Publication
First Author: Kim HJ
Year: 2015
Journal: J Neurosci
Title: REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II.
Volume: 35
Issue: 44
Pages: 14872-84
Publication
First Author: Li H
Year: 2022
Journal: Cell Death Dis
Title: Downregulation of REST in the cochlea contributes to age-related hearing loss via the p53 apoptosis pathway.
Volume: 13
Issue: 4
Pages: 343
Publication
First Author: Jørgensen HF
Year: 2009
Journal: Development
Title: REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells.
Volume: 136
Issue: 5
Pages: 715-21
Publication
First Author: Zhang D
Year: 2017
Journal: Nucleic Acids Res
Title: Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.
Volume: 45
Issue: 6
Pages: 3102-3115
Publication
First Author: Cloud AS
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesis.
Volume: 119
Issue: 44
Pages: e2205524119
Publication
First Author: Aoki H
Year: 2012
Journal: Development
Title: Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis.
Volume: 139
Issue: 4
Pages: 667-77
Publication
First Author: Mao CA
Year: 2011
Journal: Dev Biol
Title: Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development.
Volume: 349
Issue: 1
Pages: 90-9
Publication
First Author: Seki M
Year: 2014
Journal: PLoS One
Title: A comparison of the rest complex binding patterns in embryonic stem cells and epiblast stem cells.
Volume: 9
Issue: 4
Pages: e95374
Publication
First Author: Ren X
Year: 2011
Journal: Mol Cell Biol
Title: REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elements.
Volume: 31
Issue: 10
Pages: 2100-10
Publication
First Author: Kimura R
Year: 2022
Journal: Dev Dyn
Title: Detection of REST expression in the testis using epitope-tag knock-in mice generated by genome editing.
Volume: 251
Issue: 3
Pages: 525-535
Publication  
First Author: Tuomainen T
Year: 2022
Journal: Cells
Title: PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes.
Volume: 11
Issue: 19
Publication
First Author: Martin D
Year: 2012
Journal: PLoS One
Title: Specific silencing of the REST target genes in insulin-secreting cells uncovers their participation in beta cell survival.
Volume: 7
Issue: 9
Pages: e45844
Publication
First Author: Kim M
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Regulation of REST levels overcomes dysregulation of neural stem cell differentiation caused by disruption of polyubiquitin gene Ubb.
Volume: 486
Issue: 1
Pages: 171-177
Publication
First Author: Pajarillo E
Year: 2020
Journal: J Biol Chem
Title: The transcription factor REST up-regulates tyrosine hydroxylase and antiapoptotic genes and protects dopaminergic neurons against manganese toxicity.
Volume: 295
Issue: 10
Pages: 3040-3054
Publication
First Author: Aoki H
Year: 2015
Journal: Genes Cells
Title: White spotting phenotype induced by targeted REST disruption during neural crest specification to a melanocyte cell lineage.
Volume: 20
Issue: 5
Pages: 439-49
Publication
First Author: Ryan BJ
Year: 2021
Journal: J Neurosci
Title: REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model.
Volume: 41
Issue: 16
Pages: 3731-3746
GXD Expression    
Probe: MGI:6182116
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191201
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Rest
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6182116
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191201
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Rest
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6182116
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191201
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Rest
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6182116
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191201
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Rest
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6182116
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191201
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Rest
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6182116
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191201
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Rest
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6182116
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191201
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Rest
Detected: true
Specimen Num: 7
Publication
First Author: Yamada Y
Year: 2010
Journal: Cell Stem Cell
Title: Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance.
Volume: 6
Issue: 1
Pages: 10-5
Publication
First Author: Aoki H
Year: 2014
Journal: Genes Cells
Title: Neonatal lethality of neural crest cell-specific Rest knockout mice is associated with gastrointestinal distension caused by aberrations of myenteric plexus.
Volume: 19
Issue: 10
Pages: 723-42
Publication
First Author: Aoki H
Year: 2016
Journal: PLoS One
Title: Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells.
Volume: 11
Issue: 9
Pages: e0163042
Publication
First Author: van der Rest ME
Year: 2000
Journal: J Bacteriol
Title: Functions of the membrane-associated and cytoplasmic malate dehydrogenases in the citric acid cycle of Escherichia coli.
Volume: 182
Issue: 24
Pages: 6892-9
Publication
First Author: Li J
Year: 2022
Journal: Nucleic Acids Res
Title: The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity.
Volume: 50
Issue: 18
Pages: 10343-10359
Protein Domain
Type: Homologous_superfamily
Description: Telomere resolvase ResT (protelomerase) catalyses the conversion of linear double-stranded DNA into hairpin telomeres [].
Protein Domain
Type: Family
Description: Telomere resolvase ResT (protelomerase) catalyses the conversion of linear double-stranded DNA into hairpin telomeres [].
Publication
First Author: Volvert ML
Year: 2014
Journal: Cell Rep
Title: MicroRNA targeting of CoREST controls polarization of migrating cortical neurons.
Volume: 7
Issue: 4
Pages: 1168-83
GO Term
Publication  
First Author: Nakano Y
Year: 2020
Journal: Life Sci Alliance
Title: Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse.
Volume: 3
Issue: 12
Publication  
First Author: Elsen GE
Year: 2018
Journal: Front Neurosci
Title: The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.
Volume: 12
Pages: 571
Publication
First Author: Jørgensen HF
Year: 2010
Journal: Nature
Title: Can controversies be put to REST?
Volume: 467
Issue: 7311
Pages: E3-4; discussion E5
Publication    
First Author: Giusti SA
Year: 2014
Journal: Elife
Title: MicroRNA-9 controls dendritic development by targeting REST.
Volume: 3
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chimpanzee