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Search results 1 to 100 out of 271 for Rgs1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
5996 | RGS1
Type: gene
Organism: human
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Gene
496714 | rgs1
Type: gene
Organism: frog, western clawed
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Gene
54289 | Rgs1
Type: gene
Organism: rat
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Gene
488585 | RGS1
Type: gene
Organism: dog, domestic
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Gene
457594 | RGS1
Type: gene
Organism: chimpanzee
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Gene
540836 | RGS1
Type: gene
Organism: cattle
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Gene
424360 | RGS1
Type: gene
Organism: chicken
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Gene
556179 | rgs1
Type: gene
Organism: zebrafish
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Gene
712754 | RGS1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1354694 | Rgs1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR030409 | RGS1
Type: Family
Description: RGS1 belongs to the the Regulators of G protein Signaling (RGS) protein family, whose members control the activity of G proteins through the acceleration of GTPase activity of the alpha subunits of G proteins []. RGS1 may be involved in the regulation of B-cell activation and proliferation []. The genetic variants in the RGS gene have been linked to susceptibility to coeliac disease (CD), an autoimmune disorder of the small intestine [].
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Protein
Q9JL25
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: false
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Publication
20555355 | -
First Author: International Multiple Sclerosis Genetics Conssortium (IMSGC).
Year: 2010
Journal: Genes Immun
Title: IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci.
Volume: 11
Issue: 5
Pages: 397-405
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Publication
27029527 | J:315448
First Author: Caballero-Franco C
Year: 2016
Journal: Genes Immun
Title: The autoimmunity-associated gene RGS1 affects the frequency of T follicular helper cells.
Volume: 17
Issue: 4
Pages: 228-38
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Publication
25782711 | J:221876
 
First Author: Patel J
Year: 2015
Journal: Nat Commun
Title: RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling.
Volume: 6
Pages: 6614
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Publication
15780991 | J:97001
First Author: Han SB
Year: 2005
Journal: Immunity
Title: Rgs1 and Gnai2 regulate the entrance of B lymphocytes into lymph nodes and B cell motility within lymph node follicles.
Volume: 22
Issue: 3
Pages: 343-54
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Publication
20508603 | J:186899
First Author: Hwang IY
Year: 2010
Journal: Genes Immun
Title: Variations in Gnai2 and Rgs1 expression affect chemokine receptor signaling and the organization of secondary lymphoid organs.
Volume: 11
Issue: 5
Pages: 384-96
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Protein
A0A0A0MQN0
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: false
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Publication
8473738 | -
First Author: Hong JX
Year: 1993
Journal: J Immunol
Title: Isolation and characterization of a novel B cell activation gene.
Volume: 150
Issue: 9
Pages: 3895-904
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Publication
23464602 | -
First Author: Sethakorn N
Year: 2013
Journal: J Recept Signal Transduct Res
Title: RGS expression in cancer: oncomining the cancer microarray data.
Volume: 33
Issue: 3
Pages: 166-71
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Protein
A0A087WS51
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: true
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Publication
21795595 | J:179138
First Author: Gibbons DL
Year: 2011
Journal: J Immunol
Title: Cutting Edge: Regulator of G protein signaling-1 selectively regulates gut T cell trafficking and colitic potential.
Volume: 187
Issue: 5
Pages: 2067-71
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Publication
15100254 | J:89680
First Author: Shi GX
Year: 2004
Journal: J Immunol
Title: Toll-like receptor signaling alters the expression of regulator of G protein signaling proteins in dendritic cells: implications for G protein-coupled receptor signaling.
Volume: 172
Issue: 9
Pages: 5175-84
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Publication
37153600 | J:340990
 
First Author: von Werdt D
Year: 2023
Journal: Front Immunol
Title: Regulator of G-protein signaling 1 critically supports CD8(+) T(RM) cell-mediated intestinal immunity.
Volume: 14
Pages: 1085895
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Publication
29654907 | J:324517
 
First Author: Patel J
Year: 2018
Journal: Vascul Pharmacol
Title: Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II-mediated blood pressure control.
Volume: 108
Pages: 15-22
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Protein Coding Gene
MGP_CAROLIEiJ_G0014680 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016567 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016550 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016515 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016510 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016335 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1354694 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016971 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015914 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016309 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016415 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016413 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016486 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016439 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017007 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015700 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015977 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027916 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015487 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15199133 | J:90780
First Author: Moratz C
Year: 2004
Journal: Mol Cell Biol
Title: Abnormal B-cell responses to chemokines, disturbed plasma cell localization, and distorted immune tissue architecture in Rgs1-/- mice.
Volume: 24
Issue: 13
Pages: 5767-75
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Publication
- | J:61058
   
First Author: Reif K
Year: 2000
Journal: GenBank Submission
Title: Mus musculus regulator of G-protein signaling 1 mRNA, complete cds
Pages: AF215667
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Publication
16365832 | J:109577
First Author: Fullerton J
Year: 2006
Journal: Behav Genet
Title: New approaches to the genetic analysis of neuroticism and anxiety.
Volume: 36
Issue: 1
Pages: 147-61
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Publication
30683698 | J:272934
First Author: Vural A
Year: 2019
Journal: J Immunol
Title: Gαi2 Signaling Regulates Inflammasome Priming and Cytokine Production by Biasing Macrophage Phenotype Determination.
Volume: 202
Issue: 5
Pages: 1510-1520
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Publication
15489855 | J:93903
First Author: Yalcin B
Year: 2004
Journal: Nat Genet
Title: Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice.
Volume: 36
Issue: 11
Pages: 1197-202
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Publication
11342430 | J:69278
First Author: Nagata Y
Year: 2001
Journal: Blood
Title: A novel regulator of G-protein signaling bearing GAP activity for Galphai and Galphaq in megakaryocytes.
Volume: 97
Issue: 10
Pages: 3051-60
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Publication
11829488 | J:74612
First Author: Sierra DA
Year: 2002
Journal: Genomics
Title: Evolution of the regulators of G-protein signaling multigene family in mouse and human.
Volume: 79
Issue: 2
Pages: 177-85
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Publication
21308776 | J:233118
First Author: Abdallah BM
Year: 2011
Journal: J Bone Miner Res
Title: DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Volume: 26
Issue: 7
Pages: 1457-71
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Publication
23012479 | J:190322
First Author: Archambaud C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Impact of lactobacilli on orally acquired listeriosis.
Volume: 109
Issue: 41
Pages: 16684-9
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Publication
- | J:29505
     
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q9JL25-2
Organism: Mus musculus/domesticus
Length: 162  
Fragment?: false
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Allele
Rgs1<em1Smoc> | MGI:7292037
Name: regulator of G-protein signaling 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6476171 | C57BL/6JSmoc-Rgs1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
16565322 | -
First Author: Han JI
Year: 2006
Journal: J Leukoc Biol
Title: RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization.
Volume: 79
Issue: 6
Pages: 1357-68
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Publication
26528314 | -
 
First Author: Huang JP
Year: 2015
Journal: Front Plant Sci
Title: Cooperative control between AtRGS1 and AtHXK1 in a WD40-repeat protein pathway in Arabidopsis thaliana.
Volume: 6
Pages: 851
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Protein Domain
IPR016803 | RHIP1
Type: Family
Description: RHIP1 provides a physical connection between the glucose signaling sensors RGS1 and HXK1, and is required for some glucose-regulated gene expression in plants [].
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Publication
12193720 | J:78572
First Author: Shi GX
Year: 2002
Journal: J Immunol
Title: RGS13 regulates germinal center B lymphocytes responsiveness to CXC chemokine ligand (CXCL)12 and CXCL13.
Volume: 169
Issue: 5
Pages: 2507-15
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Publication
18624922 | J:138851
First Author: Cervia D
Year: 2008
Journal: J Neurochem
Title: Modulation of the neuronal response to ischaemia by somatostatin analogues in wild-type and knock-out mouse retinas.
Volume: 106
Issue: 5
Pages: 2224-35
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Publication
10364456 | J:55700
First Author: Panetta R
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Regulators of G-protein signaling (RGS) 1 and 16 are induced in response to bacterial lipopolysaccharide and stimulate c-fos promoter expression.
Volume: 259
Issue: 3
Pages: 550-6
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Publication
35982907 | J:345871
First Author: Ko DS
Year: 2022
Journal: Int J Biol Sci
Title: Role of PCK2 in the proliferation of vascular smooth muscle cells in neointimal hyperplasia.
Volume: 18
Issue: 13
Pages: 5154-5167
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Publication
27561966 | J:356030
First Author: Moreno-Viedma V
Year: 2016
Journal: Cardiovasc Diabetol
Title: Common dysregulated pathways in obese adipose tissue and atherosclerosis.
Volume: 15
Issue: 1
Pages: 120
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Publication
18026105 | J:130209
First Author: Bansal G
Year: 2008
Journal: Nat Immunol
Title: Suppression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13.
Volume: 9
Issue: 1
Pages: 73-80
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Protein Domain
IPR034954 | RGS13
Type: Family
Description: RGS13 is a member of R4 subfamily of RGS family, a diverse group of multifunctional proteins that regulate cellular signaling events downstream of G-protein coupled receptors (GPCRs) []. Signaling is initiated when GPCRs bind to their ligands, triggering the replacement of GDP bound to the G-alpha subunits of heterotrimeric G proteins with GTP. RGSs inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. This activity defines them as GTPase activating proteins (GAPs).RGS13 exhibits relatively restricted tissue expression in T and B lymphocytes, as well as mast cells (MCs). RGS13 acts together with RGS1 to regulate chemokine receptor signaling in germinal centre B lymphocytes [, ]. In MCs, it inhibits G protein-coupled receptor signaling and suppresses IgE-antigen-induced MC degranulation and anaphylaxis [].
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Protein
G3UX14
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: true
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Protein
A0A0G2JEW1
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: false
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Protein
F6Y9P3
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: true
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Publication
10811618 | -
First Author: Spink KE
Year: 2000
Journal: EMBO J
Title: Structural basis of the Axin-adenomatous polyposis coli interaction.
Volume: 19
Issue: 10
Pages: 2270-9
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Publication
10452897 | -
First Author: de Alba E
Year: 1999
Journal: J Mol Biol
Title: Solution structure of human GAIP (Galpha interacting protein): a regulator of G protein signaling.
Volume: 291
Issue: 4
Pages: 927-39
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Publication
11234020 | -
First Author: Slep KC
Year: 2001
Journal: Nature
Title: Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
Volume: 409
Issue: 6823
Pages: 1071-7
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Publication
12764189 | -
First Author: Lodowski DT
Year: 2003
Journal: Science
Title: Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma.
Volume: 300
Issue: 5623
Pages: 1256-62
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Publication
10836135 | -
 
First Author: De Vries L
Year: 2000
Journal: Annu Rev Pharmacol Toxicol
Title: The regulator of G protein signaling family.
Volume: 40
Pages: 235-71
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Publication
15090201 | -
First Author: Chasse SA
Year: 2003
Journal: Assay Drug Dev Technol
Title: RGS proteins: G protein-coupled receptors meet their match.
Volume: 1
Issue: 2
Pages: 357-64
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Publication
18434541 | -
First Author: Soundararajan M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Volume: 105
Issue: 17
Pages: 6457-62
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Publication
23900842 | -
First Author: Croft W
Year: 2013
Journal: J Biol Chem
Title: A physiologically required G protein-coupled receptor (GPCR)-regulator of G protein signaling (RGS) interaction that compartmentalizes RGS activity.
Volume: 288
Issue: 38
Pages: 27327-42
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Protein
P97428
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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