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Search results 1 to 100 out of 269 for Rgs1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: RGS1 belongs to the the Regulators of G protein Signaling (RGS) protein family, whose members control the activity of G proteins through the acceleration of GTPase activity of the alpha subunits of G proteins []. RGS1 may be involved in the regulation of B-cell activation and proliferation []. The genetic variants in the RGS gene have been linked to susceptibility to coeliac disease (CD), an autoimmune disorder of the small intestine [].
Protein
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: false
Publication
First Author: International Multiple Sclerosis Genetics Conssortium (IMSGC).
Year: 2010
Journal: Genes Immun
Title: IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci.
Volume: 11
Issue: 5
Pages: 397-405
Publication
First Author: Caballero-Franco C
Year: 2016
Journal: Genes Immun
Title: The autoimmunity-associated gene RGS1 affects the frequency of T follicular helper cells.
Volume: 17
Issue: 4
Pages: 228-38
Publication  
First Author: Patel J
Year: 2015
Journal: Nat Commun
Title: RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling.
Volume: 6
Pages: 6614
Publication
First Author: Han SB
Year: 2005
Journal: Immunity
Title: Rgs1 and Gnai2 regulate the entrance of B lymphocytes into lymph nodes and B cell motility within lymph node follicles.
Volume: 22
Issue: 3
Pages: 343-54
Publication
First Author: Hwang IY
Year: 2010
Journal: Genes Immun
Title: Variations in Gnai2 and Rgs1 expression affect chemokine receptor signaling and the organization of secondary lymphoid organs.
Volume: 11
Issue: 5
Pages: 384-96
Protein
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: false
Publication
First Author: Hong JX
Year: 1993
Journal: J Immunol
Title: Isolation and characterization of a novel B cell activation gene.
Volume: 150
Issue: 9
Pages: 3895-904
Publication
First Author: Sethakorn N
Year: 2013
Journal: J Recept Signal Transduct Res
Title: RGS expression in cancer: oncomining the cancer microarray data.
Volume: 33
Issue: 3
Pages: 166-71
Protein
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: true
Publication
First Author: Gibbons DL
Year: 2011
Journal: J Immunol
Title: Cutting Edge: Regulator of G protein signaling-1 selectively regulates gut T cell trafficking and colitic potential.
Volume: 187
Issue: 5
Pages: 2067-71
Publication
First Author: Shi GX
Year: 2004
Journal: J Immunol
Title: Toll-like receptor signaling alters the expression of regulator of G protein signaling proteins in dendritic cells: implications for G protein-coupled receptor signaling.
Volume: 172
Issue: 9
Pages: 5175-84
Publication  
First Author: von Werdt D
Year: 2023
Journal: Front Immunol
Title: Regulator of G-protein signaling 1 critically supports CD8(+) T(RM) cell-mediated intestinal immunity.
Volume: 14
Pages: 1085895
Publication  
First Author: Patel J
Year: 2018
Journal: Vascul Pharmacol
Title: Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II-mediated blood pressure control.
Volume: 108
Pages: 15-22
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Moratz C
Year: 2004
Journal: Mol Cell Biol
Title: Abnormal B-cell responses to chemokines, disturbed plasma cell localization, and distorted immune tissue architecture in Rgs1-/- mice.
Volume: 24
Issue: 13
Pages: 5767-75
Publication    
First Author: Reif K
Year: 2000
Journal: GenBank Submission
Title: Mus musculus regulator of G-protein signaling 1 mRNA, complete cds
Pages: AF215667
Publication
First Author: Fullerton J
Year: 2006
Journal: Behav Genet
Title: New approaches to the genetic analysis of neuroticism and anxiety.
Volume: 36
Issue: 1
Pages: 147-61
Publication
First Author: Vural A
Year: 2019
Journal: J Immunol
Title: Gαi2 Signaling Regulates Inflammasome Priming and Cytokine Production by Biasing Macrophage Phenotype Determination.
Volume: 202
Issue: 5
Pages: 1510-1520
Publication
First Author: Yalcin B
Year: 2004
Journal: Nat Genet
Title: Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice.
Volume: 36
Issue: 11
Pages: 1197-202
Publication
First Author: Nagata Y
Year: 2001
Journal: Blood
Title: A novel regulator of G-protein signaling bearing GAP activity for Galphai and Galphaq in megakaryocytes.
Volume: 97
Issue: 10
Pages: 3051-60
Publication
First Author: Sierra DA
Year: 2002
Journal: Genomics
Title: Evolution of the regulators of G-protein signaling multigene family in mouse and human.
Volume: 79
Issue: 2
Pages: 177-85
Publication
First Author: Archambaud C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Impact of lactobacilli on orally acquired listeriosis.
Volume: 109
Issue: 41
Pages: 16684-9
Publication
First Author: Abdallah BM
Year: 2011
Journal: J Bone Miner Res
Title: DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Volume: 26
Issue: 7
Pages: 1457-71
Publication      
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 162  
Fragment?: false
Allele
Name: regulator of G-protein signaling 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Han JI
Year: 2006
Journal: J Leukoc Biol
Title: RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization.
Volume: 79
Issue: 6
Pages: 1357-68
Publication  
First Author: Huang JP
Year: 2015
Journal: Front Plant Sci
Title: Cooperative control between AtRGS1 and AtHXK1 in a WD40-repeat protein pathway in Arabidopsis thaliana.
Volume: 6
Pages: 851
Protein Domain
Type: Family
Description: RHIP1 provides a physical connection between the glucose signaling sensors RGS1 and HXK1, and is required for some glucose-regulated gene expression in plants [].
Publication
First Author: Shi GX
Year: 2002
Journal: J Immunol
Title: RGS13 regulates germinal center B lymphocytes responsiveness to CXC chemokine ligand (CXCL)12 and CXCL13.
Volume: 169
Issue: 5
Pages: 2507-15
Publication
First Author: Cervia D
Year: 2008
Journal: J Neurochem
Title: Modulation of the neuronal response to ischaemia by somatostatin analogues in wild-type and knock-out mouse retinas.
Volume: 106
Issue: 5
Pages: 2224-35
Publication
First Author: Panetta R
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Regulators of G-protein signaling (RGS) 1 and 16 are induced in response to bacterial lipopolysaccharide and stimulate c-fos promoter expression.
Volume: 259
Issue: 3
Pages: 550-6
Publication
First Author: Ko DS
Year: 2022
Journal: Int J Biol Sci
Title: Role of PCK2 in the proliferation of vascular smooth muscle cells in neointimal hyperplasia.
Volume: 18
Issue: 13
Pages: 5154-5167
Publication
First Author: Bansal G
Year: 2008
Journal: Nat Immunol
Title: Suppression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13.
Volume: 9
Issue: 1
Pages: 73-80
Protein Domain
Type: Family
Description: RGS13 is a member of R4 subfamily of RGS family, a diverse group of multifunctional proteins that regulate cellular signaling events downstream of G-protein coupled receptors (GPCRs) []. Signaling is initiated when GPCRs bind to their ligands, triggering the replacement of GDP bound to the G-alpha subunits of heterotrimeric G proteins with GTP. RGSs inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. This activity defines them as GTPase activating proteins (GAPs).RGS13 exhibits relatively restricted tissue expression in T and B lymphocytes, as well as mast cells (MCs). RGS13 acts together with RGS1 to regulate chemokine receptor signaling in germinal centre B lymphocytes [, ]. In MCs, it inhibits G protein-coupled receptor signaling and suppresses IgE-antigen-induced MC degranulation and anaphylaxis [].
Protein
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: true
Publication
First Author: Spink KE
Year: 2000
Journal: EMBO J
Title: Structural basis of the Axin-adenomatous polyposis coli interaction.
Volume: 19
Issue: 10
Pages: 2270-9
Publication
First Author: de Alba E
Year: 1999
Journal: J Mol Biol
Title: Solution structure of human GAIP (Galpha interacting protein): a regulator of G protein signaling.
Volume: 291
Issue: 4
Pages: 927-39
Publication
First Author: Slep KC
Year: 2001
Journal: Nature
Title: Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
Volume: 409
Issue: 6823
Pages: 1071-7
Publication
First Author: Lodowski DT
Year: 2003
Journal: Science
Title: Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma.
Volume: 300
Issue: 5623
Pages: 1256-62
Publication  
First Author: De Vries L
Year: 2000
Journal: Annu Rev Pharmacol Toxicol
Title: The regulator of G protein signaling family.
Volume: 40
Pages: 235-71
Publication
First Author: Chasse SA
Year: 2003
Journal: Assay Drug Dev Technol
Title: RGS proteins: G protein-coupled receptors meet their match.
Volume: 1
Issue: 2
Pages: 357-64
Publication
First Author: Soundararajan M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Volume: 105
Issue: 17
Pages: 6457-62
Publication
First Author: Croft W
Year: 2013
Journal: J Biol Chem
Title: A physiologically required G protein-coupled receptor (GPCR)-regulator of G protein signaling (RGS) interaction that compartmentalizes RGS activity.
Volume: 288
Issue: 38
Pages: 27327-42
Protein
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: false