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Search results 1 to 95 out of 95 for Rgs13

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Hits by Strain

Type Details Score
Gene
6003 | RGS13
Type: gene
Organism: human
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Gene
100486196 | rgs13
Type: gene
Organism: frog, western clawed
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Gene
498246 | Rgs13
Type: gene
Organism: rat
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Gene
612789 | RGS13
Type: gene
Organism: dog, domestic
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Gene
745173 | RGS13
Type: gene
Organism: chimpanzee
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Gene
506654 | RGS13
Type: gene
Organism: cattle
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Gene
429059 | RGS13
Type: gene
Organism: chicken
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Gene
712688 | RGS13
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2180585 | Rgs13
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR034954 | RGS13
Type: Family
Description: RGS13 is a member of R4 subfamily of RGS family, a diverse group of multifunctional proteins that regulate cellular signaling events downstream of G-protein coupled receptors (GPCRs) []. Signaling is initiated when GPCRs bind to their ligands, triggering the replacement of GDP bound to the G-alpha subunits of heterotrimeric G proteins with GTP. RGSs inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. This activity defines them as GTPase activating proteins (GAPs).RGS13 exhibits relatively restricted tissue expression in T and B lymphocytes, as well as mast cells (MCs). RGS13 acts together with RGS1 to regulate chemokine receptor signaling in germinal centre B lymphocytes [, ]. In MCs, it inhibits G protein-coupled receptor signaling and suppresses IgE-antigen-induced MC degranulation and anaphylaxis [].
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Publication
12193720 | J:78572
First Author: Shi GX
Year: 2002
Journal: J Immunol
Title: RGS13 regulates germinal center B lymphocytes responsiveness to CXC chemokine ligand (CXCL)12 and CXCL13.
Volume: 169
Issue: 5
Pages: 2507-15
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Protein
Q8K443
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
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Publication
18026105 | J:130209
First Author: Bansal G
Year: 2008
Journal: Nat Immunol
Title: Suppression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13.
Volume: 9
Issue: 1
Pages: 73-80
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Publication
18775326 | J:138772
First Author: Xie Z
Year: 2008
Journal: Mol Cell
Title: RGS13 acts as a nuclear repressor of CREB.
Volume: 31
Issue: 5
Pages: 660-70
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Publication
21531726 | J:174815
First Author: Iwaki S
Year: 2011
Journal: J Biol Chem
Title: p53 negatively regulates RGS13 protein expression in immune cells.
Volume: 286
Issue: 25
Pages: 22219-26
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Publication
16565322 | -
First Author: Han JI
Year: 2006
Journal: J Leukoc Biol
Title: RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization.
Volume: 79
Issue: 6
Pages: 1357-68
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Publication
23533672 | J:199530
First Author: Hwang IY
Year: 2013
Journal: PLoS One
Title: Rgs13 constrains early B cell responses and limits germinal center sizes.
Volume: 8
Issue: 3
Pages: e60139
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Publication
16226429 | -
First Author: Abramow-Newerly M
Year: 2006
Journal: Cell Signal
Title: RGS proteins have a signalling complex: interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins.
Volume: 18
Issue: 5
Pages: 579-91
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Protein Coding Gene
MGP_CAROLIEiJ_G0014679 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016566 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016549 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016514 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016509 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016334 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2180585 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016970 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015913 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016308 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016414 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016412 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016485 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016438 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017006 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015699 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015976 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027915 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015486 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4420988
Age: postnatal
Specimen Label: Heart
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4420988
Age: postnatal
Specimen Label: Brain
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:4420988
Age: postnatal
Specimen Label: Spleeen
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:4420988
Age: postnatal
Specimen Label: Lung
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4420988
Age: postnatal
Specimen Label: Liver
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:4420988
Age: postnatal
Specimen Label: Skeletal muscle
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4420988
Age: postnatal
Specimen Label: Kidney
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4420988
Age: postnatal
Specimen Label: Testis
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:4420989
Age: postnatal
Specimen Label: Stomach
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:4420989
Age: postnatal
Specimen Label: Small Intestine
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:4420989
Age: postnatal
Specimen Label: Skeletal Muscle
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4420989
Age: postnatal
Specimen Label: Testis
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:4420989
Age: postnatal
Specimen Label: Un-Pregnant Uterus
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:4420989
Age: embryonic day 17.5
Specimen Label: Placenta (17.5 dpc)
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1604225
Stage: TS25
Assay Id: MGI:4420989
Age: embryonic day 17.5
Specimen Label: Placenta (17.5 dpc)
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:4420989
Age: postnatal
Specimen Label: Thymus
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:4420990
Age: embryonic day 7.0
Specimen Label: 7
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:4420990
Age: embryonic day 11.0
Specimen Label: 11
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:4420990
Age: embryonic day 15.0
Specimen Label: 15
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4420967
Assay Type: Northern blot
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:4420990
Age: embryonic day 17.0
Specimen Label: 17
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4420994
Assay Type: RT-PCR
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:4421012
Age: postnatal
Specimen Label: Unfx.
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:4420968
Assay Type: RNA in situ
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:4421032
Age: postnatal
Specimen Label: 3C
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4420968
Assay Type: RNA in situ
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4421032
Age: postnatal
Note: Peyer's patches in the ileum.
Specimen Label: 3J
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4420968
Assay Type: RNA in situ
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4421032
Age: postnatal
Note: Peyer's patches in the ileum.
Specimen Label: 3K
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:4420968
Assay Type: RNA in situ
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2576527
Stage: TS27
Assay Id: MGI:4421032
Age: postnatal newborn
Note: The authors state in the text that they did not see any expression upon examining sagittal sections of newborn mice.
Specimen Label: not shown newborn
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:4420965
Assay Type: Immunohistochemistry
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1930528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4421030
Age: postnatal
Specimen Label: 3O
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4420968
Assay Type: RNA in situ
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1930528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4421032
Age: postnatal
Note: Expression is in the epithelial cells in the medullary region of the thymus.
Specimen Label: 3L
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4420968
Assay Type: RNA in situ
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1930528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4421032
Age: postnatal
Note: Expression is in the epithelial cells in the medullary region of the thymus.
Specimen Label: 3M
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:4420968
Assay Type: RNA in situ
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:4421032
Age: embryonic day 12.5
Note: The authors state that they did not see any expression by in situ hybridization upon examining sagittal sections.
Specimen Label: not shown e12.5
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4420968
Assay Type: RNA in situ
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:4421032
Age: embryonic day 14.5
Note: The authors state that they did not see any expression by in situ hybridization upon examining sagittal sections.
Specimen Label: not shown e14.5
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4420968
Assay Type: RNA in situ
Annotation Date: 2010-02-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:4421032
Age: embryonic day 17.5
Note: The authors state that they did not see any expression by in situ hybridization upon examining sagittal sections.
Specimen Label: not shown e17.5
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4420965
Assay Type: Immunohistochemistry
Annotation Date: 2010-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3580928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4421030
Age: postnatal
Note: Expression is in the germinal center.
Specimen Label: 3I
Detected: true
Specimen Num: 1
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Publication
15489855 | J:93903
First Author: Yalcin B
Year: 2004
Journal: Nat Genet
Title: Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice.
Volume: 36
Issue: 11
Pages: 1197-202
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Publication
11829488 | J:74612
First Author: Sierra DA
Year: 2002
Journal: Genomics
Title: Evolution of the regulators of G-protein signaling multigene family in mouse and human.
Volume: 79
Issue: 2
Pages: 177-85
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Publication
15102471 | J:114108
First Author: Papin J
Year: 2004
Journal: Curr Opin Biotechnol
Title: Bioinformatics and cellular signaling.
Volume: 15
Issue: 1
Pages: 78-81
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Allele
Rgs13<em1Smoc> | MGI:7292040
Name: regulator of G-protein signaling 13; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Shi GX (2002)
Description: RGS13 regulates germinal center B lymphocytes responsiveness to CXC chemokine ligand (CXCL)12 and CXCL13.
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Strain
MGI:6476173 | C57BL/6JSmoc-Rgs13<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
18157131 | J:131634
First Author: Hsu HC
Year: 2008
Journal: Nat Immunol
Title: Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice.
Volume: 9
Issue: 2
Pages: 166-75
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Publication
31747599 | J:298891
First Author: Ly A
Year: 2019
Journal: Cell Rep
Title: Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria.
Volume: 29
Issue: 8
Pages: 2257-2269.e6
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