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Search results 1 to 100 out of 107 for Rgs6

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1.464s

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Hits by Category

Type Details Score
Gene
9628 | RGS6
Type: gene
Organism: human
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Gene
453009 | RGS6
Type: gene
Organism: chimpanzee
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Gene
517545 | RGS6
Type: gene
Organism: cattle
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Gene
395618 | RGS6
Type: gene
Organism: chicken
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Gene
562667 | rgs6
Type: gene
Organism: zebrafish
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Gene
694620 | RGS6
Type: gene
Organism: macaque, rhesus
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Gene
100486845 | rgs6
Type: gene
Organism: frog, western clawed
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Gene
54295 | Rgs6
Type: gene
Organism: rat
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Gene
480380 | RGS6
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1354730 | Rgs6
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
32755589 | J:316073
First Author: Gao Y
Year: 2020
Journal: Cell Rep
Title: RGS6 Mediates Effects of Voluntary Running on Adult Hippocampal Neurogenesis.
Volume: 32
Issue: 5
Pages: 107997
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Publication
23338613 | J:196894
First Author: Yang J
Year: 2013
Journal: Cancer Res
Title: G-protein inactivator RGS6 mediates myocardial cell apoptosis and cardiomyopathy caused by doxorubicin.
Volume: 73
Issue: 6
Pages: 1662-7
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Publication
25501001 | J:222655
First Author: Bifsha P
Year: 2014
Journal: PLoS Genet
Title: Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra.
Volume: 10
Issue: 12
Pages: e1004863
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Publication
32513692 | J:294115
First Author: Anderson A
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells.
Volume: 117
Issue: 25
Pages: 14522-14531
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Publication
27713144 | J:314298
First Author: Yang J
Year: 2016
Journal: Oncotarget
Title: RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation.
Volume: 7
Issue: 43
Pages: 69159-69172
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Publication
20864673 | J:178185
First Author: Yang J
Year: 2010
Journal: Circ Res
Title: RGS6, a modulator of parasympathetic activation in heart.
Volume: 107
Issue: 11
Pages: 1345-9
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Publication
31120439 | J:290016
   
First Author: Luo Z
Year: 2019
Journal: JCI Insight
Title: Age-dependent nigral dopaminergic neurodegeneration and α-synuclein accumulation in RGS6-deficient mice.
Volume: 5
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Publication
34880111 | J:327747
 
First Author: Ahlers-Dannen KE
Year: 2022
Journal: eNeuro
Title: Protein Profiling of RGS6, a Pleiotropic Gene Implicated in Numerous Neuropsychiatric Disorders, Reveals Multi-Isoformic Expression and a Novel Brain-Specific Isoform.
Volume: 9
Issue: 1
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Publication
25646431 | J:220008
First Author: Stewart A
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Regulator of G protein signaling 6 is a critical mediator of both reward-related behavioral and pathological responses to alcohol.
Volume: 112
Issue: 7
Pages: E786-95
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Publication
22179605 | J:182452
First Author: Maity B
Year: 2012
Journal: J Biol Chem
Title: Regulator of G protein signaling 6 (RGS6) protein ensures coordination of motor movement by modulating GABAB receptor signaling.
Volume: 287
Issue: 7
Pages: 4972-81
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Publication
23598467 | J:199490
First Author: Maity B
Year: 2013
Journal: Carcinogenesis
Title: Regulator of G protein signaling 6 is a novel suppressor of breast tumor initiation and progression.
Volume: 34
Issue: 8
Pages: 1747-55
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Publication
20884879 | J:178182
First Author: Posokhova E
Year: 2010
Journal: Circ Res
Title: RGS6/Gβ5 complex accelerates IKACh gating kinetics in atrial myocytes and modulates parasympathetic regulation of heart rate.
Volume: 107
Issue: 11
Pages: 1350-4
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Publication
24318880 | J:209527
First Author: Wydeven N
Year: 2014
Journal: J Biol Chem
Title: RGS6, but not RGS4, is the dominant regulator of G protein signaling (RGS) modulator of the parasympathetic regulation of mouse heart rate.
Volume: 289
Issue: 4
Pages: 2440-9
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Publication
29668674 | J:261949
First Author: Kulkarni K
Year: 2018
Journal: PLoS One
Title: The influences of the M2R-GIRK4-RGS6 dependent parasympathetic pathway on electrophysiological properties of the mouse heart.
Volume: 13
Issue: 4
Pages: e0193798
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Publication
22371490 | J:184922
First Author: Shim H
Year: 2012
Journal: J Biol Chem
Title: Defective retinal depolarizing bipolar cells in regulators of G protein signaling (RGS) 7 and 11 double null mice.
Volume: 287
Issue: 18
Pages: 14873-9
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Publication
24204714 | J:209181
First Author: Posokhova E
Year: 2013
Journal: PLoS One
Title: Essential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variability.
Volume: 8
Issue: 10
Pages: e76973
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Publication
24421401 | J:211611
First Author: Stewart A
Year: 2014
Journal: FASEB J
Title: Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis.
Volume: 28
Issue: 4
Pages: 1735-44
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Publication
29079565 | J:320799
 
First Author: Chakravarti B
Year: 2017
Journal: J Am Heart Assoc
Title: Essentiality of Regulator of G Protein Signaling 6 and Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II in Notch Signaling and Cardiovascular Development.
Volume: 6
Issue: 11
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Protein Coding Gene
MGP_CAROLIEiJ_G0017917 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019911 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019868 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019844 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019848 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019654 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1354730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019203 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019625 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019740 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019726 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019765 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020334 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019255 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029673 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018762 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6730172
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3515224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6730345
Age: embryonic day 16.5
Specimen Label: S8B
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6730172
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3542824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6730345
Age: embryonic day 16.5
Note: Expressed in transitional sinoatrial conduction pathways (Hcn4-/Rgs6+, or Hcn4+/Rgs6+).
Specimen Label: 8C-0
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6730172
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3542824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6730345
Age: embryonic day 16.5
Note: Expressed in transitional sinoatrial conduction pathways (Hcn4-/Rgs6+, or Hcn4+/Rgs6+).
Specimen Label: 8C-90
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6730172
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3542824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6730345
Age: embryonic day 16.5
Note: Expressed in transitional sinoatrial conduction pathways (Hcn4-/Rgs6+, or Hcn4+/Rgs6+).
Specimen Label: 8C-225
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6730172
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3577224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6730345
Age: embryonic day 16.5
Note: Coexpressed with Hcn4.
Specimen Label: 8C-0
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6730172
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3577224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6730345
Age: embryonic day 16.5
Note: Coexpressed with Hcn4.
Specimen Label: 8C-90
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6730172
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3577224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6730345
Age: embryonic day 16.5
Note: Coexpressed with Hcn4.
Specimen Label: 8C-225
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6730172
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3577224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6730370
Age: embryonic day 16.5
Note: Expressed in the compact sinoatrial node and transitional cells.
Specimen Label: S5D
Detected: true
Specimen Num: 1
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Publication
- | J:61056
   
First Author: He W
Year: 1998
Journal: GenBank Submission
Title: Mus musculus regulator of G-protein signaling 6 mRNA, partial cds
Pages: AF061933
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Publication
24755289 | J:213237
 
First Author: Ostrovskaya O
Year: 2014
Journal: Elife
Title: RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling.
Volume: 3
Pages: e02053
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Publication
29352184 | J:260122
First Author: Anderson A
Year: 2018
Journal: Sci Rep
Title: Expression and relevance of the G protein-gated K+ channel in the mouse ventricle.
Volume: 8
Issue: 1
Pages: 1192
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Publication
22689652 | J:185272
First Author: Orlandi C
Year: 2012
Journal: J Cell Biol
Title: GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes.
Volume: 197
Issue: 6
Pages: 711-9
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Publication
20616094 | J:163324
First Author: Villasenor A
Year: 2010
Journal: Dis Model Mech
Title: Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes.
Volume: 3
Issue: 9-10
Pages: 567-80
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Publication
15897264 | J:100172
First Author: Drenan RM
Year: 2005
Journal: J Cell Biol
Title: Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family.
Volume: 169
Issue: 4
Pages: 623-33
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Publication
31284824 | J:306155
First Author: Goodyer WR
Year: 2019
Journal: Circ Res
Title: Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution.
Volume: 125
Issue: 4
Pages: 379-397
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Publication
11342430 | J:69278
First Author: Nagata Y
Year: 2001
Journal: Blood
Title: A novel regulator of G-protein signaling bearing GAP activity for Galphai and Galphaq in megakaryocytes.
Volume: 97
Issue: 10
Pages: 3051-60
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Publication
27568557 | J:239022
First Author: Klein AD
Year: 2016
Journal: Cell Rep
Title: Identification of Modifier Genes in a Mouse Model of Gaucher Disease.
Volume: 16
Issue: 10
Pages: 2546-2553
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Publication
11829488 | J:74612
First Author: Sierra DA
Year: 2002
Journal: Genomics
Title: Evolution of the regulators of G-protein signaling multigene family in mouse and human.
Volume: 79
Issue: 2
Pages: 177-85
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Publication
- | J:29505
     
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
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Publication
19906978 | J:154739
First Author: Quina LA
Year: 2009
Journal: J Neurosci
Title: Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.
Volume: 29
Issue: 45
Pages: 14309-22
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
21873635 | J:265628
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Protein
Q9Z2H2
Organism: Mus musculus/domesticus
Length: 472  
Fragment?: false
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Publication
14734556 | -
First Author: Liu Z
Year: 2004
Journal: J Biol Chem
Title: RGS6 interacts with DMAP1 and DNMT1 and inhibits DMAP1 transcriptional repressor activity.
Volume: 279
Issue: 14
Pages: 14120-8
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Publication
12140291 | -
First Author: Liu Z
Year: 2002
Journal: J Biol Chem
Title: RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6.
Volume: 277
Issue: 40
Pages: 37832-9
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Publication
12761221 | -
First Author: Chatterjee TK
Year: 2003
Journal: J Biol Chem
Title: Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants.
Volume: 278
Issue: 32
Pages: 30261-71
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GO Term
GO:0070313 | RGS6-DNMT1-DMAP1 complex
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Publication
19521673 | -
First Author: Anderson GR
Year: 2009
Journal: Cell Biochem Biophys
Title: The R7 RGS protein family: multi-subunit regulators of neuronal G protein signaling.
Volume: 54
Issue: 1-3
Pages: 33-46
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Protein Domain
IPR037956 | RGS6_RGS
Type: Domain
Description: This entry represents the RGS domain of RGS6 (regulator of G-protein signaling 6). RGS6 is a member of the R7 RGS protein subfamily. Other members of the R7 subfamily (Neuronal RGS) include: RGS7, RGS9, and RGS11, all of which are expressed predominantly in the nervous system, form an obligatory complex with G-beta-5, and play important roles in the regulation of crucial neuronal processes such as vision and motor control []. RGS6 exists in multiple splice isoforms with identical RGS domains, but possess complete or incomplete GGL domains and distinct N- and C-terminal domains []. RGS6 interacts with SCG10, a neuronal growth-associated protein and therefore regulates neuronal differentiation []. Another RGS6-binding protein is DMAP1, a component of the Dnmt1 complex involved in repression of newly replicated genes [].
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Publication
21859827 | J:177050
First Author: Huang J
Year: 2011
Journal: Cancer Res
Title: Regulator of G protein signaling 6 mediates doxorubicin-induced ATM and p53 activation by a reactive oxygen species-dependent mechanism.
Volume: 71
Issue: 20
Pages: 6310-9
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Protein
A0A087WQG6
Organism: Mus musculus/domesticus
Length: 465  
Fragment?: false
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Protein
A0A087WSJ9
Organism: Mus musculus/domesticus
Length: 435  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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