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Search results 1 to 100 out of 117 for Rhbdf2

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Geesala R
Year: 2019
Journal: J Leukoc Biol
Title: Loss of RHBDF2 results in an early-onset spontaneous murine colitis.
Volume: 105
Issue: 4
Pages: 767-781
Publication
First Author: Levy R
Year: 2020
Journal: Sci Rep
Title: A genome-wide association study in mice reveals a role for Rhbdf2 in skeletal homeostasis.
Volume: 10
Issue: 1
Pages: 3286
Publication
First Author: Hosur V
Year: 2017
Journal: BMC Res Notes
Title: Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease.
Volume: 10
Issue: 1
Pages: 573
Publication
First Author: Hosur V
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.
Volume: 111
Issue: 21
Pages: E2200-9
Publication
First Author: Hosur V
Year: 2017
Journal: Biol Open
Title: Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis.
Volume: 6
Issue: 8
Pages: 1174-1179
Publication  
First Author: Maruthappu T
Year: 2017
Journal: Nat Commun
Title: Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16.
Volume: 8
Pages: 14174
Publication
First Author: Arcidiacono P
Year: 2018
Journal: Nat Commun
Title: p63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response.
Volume: 9
Issue: 1
Pages: 1021
Publication
First Author: Siggs OM
Year: 2014
Journal: Biol Open
Title: Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.
Volume: 3
Issue: 12
Pages: 1151-7
Publication
First Author: Li X
Year: 2017
Journal: J Cell Sci
Title: Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.
Volume: 130
Issue: 5
Pages: 868-878
Publication
First Author: Issuree PD
Year: 2013
Journal: J Clin Invest
Title: iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.
Volume: 123
Issue: 2
Pages: 928-32
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: Zhang Z
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for LosTNF2 (Last updated March 25, 2015)
Publication      
First Author: Zhang Z
Year: 2014
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for LosTNF
Publication  
First Author: Badenes M
Year: 2020
Journal: Mol Metab
Title: Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis.
Volume: 31
Pages: 67-84
Publication
First Author: Kim JH
Year: 2018
Journal: Sci Rep
Title: Role of iRhom2 in intestinal ischemia-reperfusion-mediated acute lung injury.
Volume: 8
Issue: 1
Pages: 3797
Publication
First Author: Luo WW
Year: 2017
Journal: PLoS Pathog
Title: iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA.
Volume: 13
Issue: 11
Pages: e1006693
Publication  
First Author: Skurski J
Year: 2020
Journal: Metabolism
Title: Loss of iRhom2 accelerates fat gain and insulin resistance in diet-induced obesity despite reduced adipose tissue inflammation.
Volume: 106
Pages: 154194
Publication  
First Author: Sundaram B
Year: 2019
Journal: Sci Signal
Title: iRhom2 inhibits bile duct obstruction-induced liver fibrosis.
Volume: 12
Issue: 605
Publication
First Author: Chaohui C
Year: 2018
Journal: Biochem Biophys Res Commun
Title: iRhom2 promotes atherosclerosis through macrophage inflammation and induction of oxidative stress.
Volume: 503
Issue: 3
Pages: 1897-1904
Publication  
First Author: Xu M
Year: 2020
Journal: Mol Metab
Title: Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation.
Volume: 34
Pages: 112-123
GXD Expression    
Probe: MGI:5705736
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705765
Age: postnatal
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5705736
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705765
Age: postnatal
Image: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5705737
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705766
Age: postnatal
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5705737
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705766
Age: postnatal
Image: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5705738
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705767
Age: postnatal
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5705738
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705767
Age: postnatal
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5705739
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705768
Age: postnatal
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5705739
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705768
Age: postnatal
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5705740
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705769
Age: postnatal
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5705740
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705769
Age: postnatal
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5705741
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705770
Age: postnatal
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5705741
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705770
Age: postnatal
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5705742
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705773
Age: postnatal
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5705742
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705773
Age: postnatal
Image: 2
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3649828
Stage: TS28
Assay Id: MGI:5705763
Age: postnatal week 2
Image: 3B (right)
Detected: false
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5705763
Age: embryonic day 18.5
Image: 3B (left)
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3279328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5705763
Age: postnatal week 2
Image: 3B (right)
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3279228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5705763
Age: postnatal week 2
Image: 3B (right)
Detected: true
Specimen Num: 2
Publication
First Author: Zettl M
Year: 2011
Journal: Cell
Title: Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling.
Volume: 145
Issue: 1
Pages: 79-91
Publication
First Author: Christova Y
Year: 2013
Journal: EMBO Rep
Title: Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation.
Volume: 14
Issue: 10
Pages: 884-90
Publication
First Author: Cavadas M
Year: 2017
Journal: Cell Rep
Title: Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE.
Volume: 21
Issue: 3
Pages: 745-757
Publication
First Author: Hosur V
Year: 2020
Journal: Genome Biol
Title: Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation.
Volume: 21
Issue: 1
Pages: 168
Publication
First Author: Luo WW
Year: 2016
Journal: Nat Immunol
Title: iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.
Volume: 17
Issue: 9
Pages: 1057-66
Publication    
First Author: Lora J
Year: 2021
Journal: J Biol Chem
Title: Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.
Pages: 100733
Publication
First Author: Qing X
Year: 2018
Journal: J Clin Invest
Title: iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.
Volume: 128
Issue: 4
Pages: 1397-1412
Publication
First Author: Tang B
Year: 2020
Journal: FASEB J
Title: Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
Volume: 34
Issue: 4
Pages: 4956-4969
Publication    
First Author: Künzel U
Year: 2018
Journal: Elife
Title: FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.
Volume: 7
Publication    
First Author: Oikonomidi I
Year: 2018
Journal: Elife
Title: iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.
Volume: 7
Publication
First Author: Ge CX
Year: 2017
Journal: Biochem Biophys Res Commun
Title: iRhom2 deficiency relieves TNF-α associated hepatic dyslipidemia in long-term PM2.5-exposed mice.
Volume: 493
Issue: 4
Pages: 1402-1409
Publication
First Author: Maretzky T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
Volume: 110
Issue: 28
Pages: 11433-8
Publication  
First Author: Fang R
Year: 2020
Journal: Int J Mol Sci
Title: Role of iRhoms 1 and 2 in Endochondral Ossification.
Volume: 21
Issue: 22
Publication
First Author: Adrain C
Year: 2012
Journal: Science
Title: Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE.
Volume: 335
Issue: 6065
Pages: 225-8
Publication    
First Author: Grieve AG
Year: 2017
Journal: Elife
Title: Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.
Volume: 6
Publication
First Author: McIlwain DR
Year: 2012
Journal: Science
Title: iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.
Volume: 335
Issue: 6065
Pages: 229-32
Publication
First Author: Qing X
Year: 2016
Journal: Eur J Immunol
Title: iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.
Volume: 46
Issue: 12
Pages: 2737-2748
Publication
First Author: Weskamp G
Year: 2020
Journal: J Biol Chem
Title: ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).
Volume: 295
Issue: 13
Pages: 4350-4358
Publication
First Author: Haxaire C
Year: 2018
Journal: Blood
Title: Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.
Volume: 132
Issue: 10
Pages: 1064-1074
Publication
First Author: Siggs OM
Year: 2012
Journal: Blood
Title: iRhom2 is required for the secretion of mouse TNFα.
Volume: 119
Issue: 24
Pages: 5769-71
Publication
First Author: Li X
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Volume: 112
Issue: 19
Pages: 6080-5
Publication
First Author: Johnson KR
Year: 2003
Journal: Genomics
Title: Curly bare (cub), a new mouse mutation on chromosome 11 causing skin and hair abnormalities, and a modifier gene (mcub) on chromosome 5.
Volume: 81
Issue: 1
Pages: 6-14
Publication
First Author: Leilei Y
Year: 2014
Journal: PLoS One
Title: iRhom2 mutation leads to aberrant hair follicle differentiation in mice.
Volume: 9
Issue: 12
Pages: e115114
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort