Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Hakem A |
Year: |
2005 |
Journal: |
Genes Dev |
Title: |
RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis. |
Volume: |
19 |
Issue: |
17 |
Pages: |
1974-9 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, targeted mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Reid T |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain. |
Volume: |
271 |
Issue: |
23 |
Pages: |
13556-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wallace SW |
Year: |
2011 |
Journal: |
Mol Cell Biol |
Title: |
The Rho target PRK2 regulates apical junction formation in human bronchial epithelial cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
81-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Segade F |
Year: |
1995 |
Journal: |
J Immunol |
Title: |
Isolation of nine gene sequences induced by silica in murine macrophages. |
Volume: |
154 |
Issue: |
5 |
Pages: |
2384-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Melendez J |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts. |
Volume: |
286 |
Issue: |
17 |
Pages: |
15132-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao B |
Year: |
2016 |
Journal: |
Elife |
Title: |
Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zandvakili I |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice. |
Volume: |
10 |
Issue: |
6 |
Pages: |
e0127923 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6115515 |
Assay Type: |
Western blot |
Annotation Date: |
2018-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6115528 |
Age: |
postnatal adult |
|
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6115515 |
Assay Type: |
Western blot |
Annotation Date: |
2018-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6115528 |
Age: |
postnatal adult |
|
|
Specimen Label: |
HET |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6115515 |
Assay Type: |
Western blot |
Annotation Date: |
2018-02-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6115528 |
Age: |
postnatal adult |
|
|
Specimen Label: |
KO |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7718468 |
Assay Type: |
Western blot |
Annotation Date: |
2024-09-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666820 |
|
Stage: |
TS20 |
Assay Id: |
MGI:7718483 |
Age: |
embryonic day 12.5 |
Image: |
8 |
|
Specimen Label: |
control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7718468 |
Assay Type: |
Western blot |
Annotation Date: |
2024-09-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666820 |
|
Stage: |
TS20 |
Assay Id: |
MGI:7718483 |
Age: |
embryonic day 12.5 |
Image: |
8 |
|
Specimen Label: |
RhoAf/f;Wnt1-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Madaule P |
Year: |
1995 |
Journal: |
FEBS Lett |
Title: |
A novel partner for the GTP-bound forms of rho and rac. |
Volume: |
377 |
Issue: |
2 |
Pages: |
243-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakamura Y |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
Modulation of Both Intrinsic and Extrinsic Factors Additively Promotes Rewiring of Corticospinal Circuits after Spinal Cord Injury. |
Volume: |
41 |
Issue: |
50 |
Pages: |
10247-10260 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yonemura S |
Year: |
2004 |
Journal: |
Exp Cell Res |
Title: |
Rho localization in cells and tissues. |
Volume: |
295 |
Issue: |
2 |
Pages: |
300-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watanabe N |
Year: |
1999 |
Journal: |
Nat Cell Biol |
Title: |
Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. |
Volume: |
1 |
Issue: |
3 |
Pages: |
136-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miki T |
Year: |
1993 |
Journal: |
Nature |
Title: |
Oncogene ect2 is related to regulators of small GTP-binding proteins. |
Volume: |
362 |
Issue: |
6419 |
Pages: |
462-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Charles JF |
Year: |
2012 |
Journal: |
Bone |
Title: |
The collection of NFATc1-dependent transcripts in the osteoclast includes numerous genes non-essential to physiologic bone resorption. |
Volume: |
51 |
Issue: |
5 |
Pages: |
902-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hall A |
Year: |
1994 |
Journal: |
Annu Rev Cell Biol |
Title: |
Small GTP-binding proteins and the regulation of the actin cytoskeleton. |
Volume: |
10 |
|
Pages: |
31-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hall A |
Year: |
1998 |
Journal: |
Science |
Title: |
Rho GTPases and the actin cytoskeleton. |
Volume: |
279 |
Issue: |
5350 |
Pages: |
509-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Babbin BA |
Year: |
2009 |
Journal: |
Am J Pathol |
Title: |
The bacterial virulence factor lymphostatin compromises intestinal epithelial barrier function by modulating rho GTPases. |
Volume: |
174 |
Issue: |
4 |
Pages: |
1347-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Causeret F |
Year: |
2004 |
Journal: |
Development |
Title: |
Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1. |
Volume: |
131 |
Issue: |
12 |
Pages: |
2841-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Escamilla CO |
Year: |
2017 |
Journal: |
Nature |
Title: |
Kctd13 deletion reduces synaptic transmission via increased RhoA. |
Volume: |
551 |
Issue: |
7679 |
Pages: |
227-231 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leslie JR |
Year: |
2012 |
Journal: |
Front Mol Neurosci |
Title: |
RhoA is dispensable for axon guidance of sensory neurons in the mouse dorsal root ganglia. |
Volume: |
5 |
|
Pages: |
67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Katayama K |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation. |
Volume: |
108 |
Issue: |
18 |
Pages: |
7607-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bertol JW |
Year: |
2022 |
Journal: |
Development |
Title: |
TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells. |
Volume: |
149 |
Issue: |
15 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Copeland NG |
Year: |
1999 |
Journal: |
Database Release |
Title: |
Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Rho-related GTP-binding protein RhoC |
Type: |
chain |
End: |
190 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
193
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Vega FM |
Year: |
2011 |
Journal: |
J Cell Biol |
Title: |
RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. |
Volume: |
193 |
Issue: |
4 |
Pages: |
655-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Giang Ho TT |
Year: |
2011 |
Journal: |
Mol Biol Cell |
Title: |
RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis. |
Volume: |
22 |
Issue: |
17 |
Pages: |
3263-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Coleman PR |
Year: |
2020 |
Journal: |
Cell Commun Signal |
Title: |
YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment. |
Volume: |
18 |
Issue: |
1 |
Pages: |
18 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
118
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
149
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Pathway |
|
•
•
•
•
•
|
Publication |
First Author: |
Unsal-Kacmaz K |
Year: |
2012 |
Journal: |
Mol Oncol |
Title: |
The interaction of PKN3 with RhoC promotes malignant growth. |
Volume: |
6 |
Issue: |
3 |
Pages: |
284-98 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|