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Search results 1 to 97 out of 97 for Rin1

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
9610 | RIN1
Type: gene
Organism: human
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Gene
466675 | RIN1
Type: gene
Organism: chimpanzee
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Gene
509295 | RIN1
Type: gene
Organism: cattle
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Gene
714321 | RIN1
Type: gene
Organism: macaque, rhesus
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Gene
100495483 | rin1
Type: gene
Organism: frog, western clawed
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Gene
207119 | Rin1
Type: gene
Organism: rat
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Gene
611928 | RIN1
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:2385695 | Rin1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
12574403 | J:81922
First Author: Dhaka A
Year: 2003
Journal: J Neurosci
Title: The RAS effector RIN1 modulates the formation of aversive memories.
Volume: 23
Issue: 3
Pages: 748-57
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Publication
19837165 | J:158323
First Author: Dzudzor B
Year: 2010
Journal: Mol Cell Neurosci
Title: Regulated expression of the Ras effector Rin1 in forebrain neurons.
Volume: 43
Issue: 1
Pages: 108-16
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Publication
19830836 | J:162182
First Author: Bliss JM
Year: 2010
Journal: J Neurosci Res
Title: Fear learning and extinction are linked to neuronal plasticity through Rin1 signaling.
Volume: 88
Issue: 4
Pages: 917-26
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Publication
18723684 | J:248205
First Author: Deininger K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neurons.
Volume: 105
Issue: 34
Pages: 12539-44
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Publication
21102429 | J:168490
First Author: Thai M
Year: 2011
Journal: Leukemia
Title: ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.
Volume: 25
Issue: 2
Pages: 290-300
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Protein Coding Gene
MGP_CAROLIEiJ_G0022531 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024688 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024654 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024627 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024654 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024422 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2385695 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025101 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023894 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0024393 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024521 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024488 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024607 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025149 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023640 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014028 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023445 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521246
Specimen Label: MRC Harwell_1521246
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521249
Specimen Label: MRC Harwell_1521249
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521246
Specimen Label: MRC Harwell_1521246
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521248
Specimen Label: MRC Harwell_1521248
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521249
Specimen Label: MRC Harwell_1521249
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1706828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521251
Specimen Label: MRC Harwell_1521251
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1753628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521246
Specimen Label: MRC Harwell_1521246
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1753628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521249
Specimen Label: MRC Harwell_1521249
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521246
Specimen Label: MRC Harwell_1521246
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521248
Specimen Label: MRC Harwell_1521248
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521249
Specimen Label: MRC Harwell_1521249
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521246
Specimen Label: MRC Harwell_1521246
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521248
Specimen Label: MRC Harwell_1521248
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521249
Specimen Label: MRC Harwell_1521249
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521250
Specimen Label: MRC Harwell_1521250
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521246
Specimen Label: MRC Harwell_1521246
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521248
Specimen Label: MRC Harwell_1521248
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521249
Specimen Label: MRC Harwell_1521249
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692563
Age: postnatal adult
Image: MRC Harwell_1521247
Specimen Label: MRC Harwell_1521247
Detected: true
Specimen Num: 2
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Publication
15525528 | J:94519
First Author: de Napoles M
Year: 2004
Journal: Dev Cell
Title: Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.
Volume: 7
Issue: 5
Pages: 663-76
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
11784866 | -
First Author: Wang Y
Year: 2002
Journal: Mol Cell Biol
Title: The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.
Volume: 22
Issue: 3
Pages: 916-26
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Publication
17403676 | -
First Author: Kong C
Year: 2007
Journal: J Biol Chem
Title: Rin1 interacts with signal-transducing adaptor molecule (STAM) and mediates epidermal growth factor receptor trafficking and degradation.
Volume: 282
Issue: 20
Pages: 15294-301
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Publication
24265854 | -
First Author: Balaji K
Year: 2013
Journal: Commun Integr Biol
Title: RIN1 regulates cell migration through RAB5 GTPases and ABL tyrosine kinases.
Volume: 6
Issue: 5
Pages: e25421
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Interaction Experiment
Han L (1997)
Description: Protein binding and signaling properties of RIN1 suggest a unique effector function.
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Publication
9144171 | -
First Author: Han L
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Protein binding and signaling properties of RIN1 suggest a unique effector function.
Volume: 94
Issue: 10
Pages: 4954-9
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Protein Domain
IPR035867 | RIN1_SH2
Type: Domain
Description: RIN1, a member of the RIN (AKA Ras interaction/interference) family, have multifunctional domains including SH2 and proline-rich (PR) domains in the N-terminal region, and RIN-family homology (RH), VPS9 and Ras-association (RA) domains in the C-terminal region. RIN proteins function as Rab5-GEFs []. Previous studies showed that RIN1 interacts with EGF receptors via its SH2 domain and regulates trafficking and degradation of EGF receptors via its interaction with STAM, indicating a vital role for RIN1 in regulating endosomal trafficking of receptor tyrosine kinases (RTKs) []. RIN1 was first identified as a Ras-binding protein that suppresses the activated RAS2 allele in S. cerevisiae. RIN1 binds to the activated Ras through its carboxyl-terminal domain and this Ras-binding domain also binds to 14-3-3 proteins as Raf-1 does [].The SH2 domain of RIN1 are thought to interact with the phosphotyrosine-containing proteins, but the physiological partners for this domain are unknown. The proline-rich domain in RIN1 is similar to the consensus SH3 binding regions.
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Publication
12787502 | -
First Author: Prag G
Year: 2003
Journal: Cell
Title: Mechanism of ubiquitin recognition by the CUE domain of Vps9p.
Volume: 113
Issue: 5
Pages: 609-20
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Publication
8628304 | -
First Author: Burd CG
Year: 1996
Journal: Mol Cell Biol
Title: A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins.
Volume: 16
Issue: 5
Pages: 2369-77
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Protein Domain
IPR041804 | Vps9_CUE
Type: Domain
Description: Vps9 is a cytosolic yeast protein required for localization of vacuolar proteins, such as the soluble vacuolar hydrolases CPY and PrA []. It may bind and act as an effector of a Rab GTPase and plays a role in vacuolar protein sorting (VPS) pathway. Vps9 contains a region called GBH domain that is related to mammalian Ras-binding proteins, Rin1 and JC265, and may negatively regulate Ras-mediated signaling in yeast Saccharomyces cerevisiae. This entry represents the N-terminal CUE domain that interacts specifically with monoubiquitin and regulates intramolecular monoubiquitylation [, ].
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Publication
11774238 | J:73314
First Author: Samant RS
Year: 2002
Journal: Int J Cancer
Title: Identification and characterization of the murine ortholog (brms1) of breast-cancer metastasis suppressor 1 (BRMS1).
Volume: 97
Issue: 1
Pages: 15-20
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Publication
33531372 | J:305587
First Author: Sutcliffe MD
Year: 2021
Journal: Cancer Res
Title: Premalignant Oligodendrocyte Precursor Cells Stall in a Heterogeneous State of Replication Stress Prior to Gliomagenesis.
Volume: 81
Issue: 7
Pages: 1868-1882
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Publication
16650848 | J:111384
First Author: Wainszelbaum MJ
Year: 2006
Journal: Exp Cell Res
Title: IL4/PGE2 induction of an enlarged early endosomal compartment in mouse macrophages is Rab5-dependent.
Volume: 312
Issue: 12
Pages: 2238-51
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Publication
12628920 | -
First Author: Shih SC
Year: 2003
Journal: EMBO J
Title: A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain.
Volume: 22
Issue: 6
Pages: 1273-81
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Protein
Q921Q7
Organism: Mus musculus/domesticus
Length: 763  
Fragment?: false
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Protein
A0A2C9F2A2
Organism: Mus musculus/domesticus
Length: 774  
Fragment?: false
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