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Search results 1 to 100 out of 982 for Ripk1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Lalaoui N
Year: 2020
Journal: Nature
Title: Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease.
Volume: 577
Issue: 7788
Pages: 103-108
Publication
First Author: Lin J
Year: 2016
Journal: Nature
Title: RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation.
Volume: 540
Issue: 7631
Pages: 124-128
Publication
First Author: Newton K
Year: 2016
Journal: Nature
Title: RIPK1 inhibits ZBP1-driven necroptosis during development.
Volume: 540
Issue: 7631
Pages: 129-133
Publication
First Author: Filliol A
Year: 2017
Journal: Sci Rep
Title: RIPK1 protects hepatocytes from death in Fas-induced hepatitis.
Volume: 7
Issue: 1
Pages: 9205
Publication
First Author: Najafov A
Year: 2021
Journal: Mol Cell
Title: RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.
Volume: 81
Issue: 2
Pages: 370-385.e7
Publication
First Author: Jaco I
Year: 2017
Journal: Mol Cell
Title: MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death.
Volume: 66
Issue: 5
Pages: 698-710.e5
Publication
First Author: Imanishi T
Year: 2023
Journal: Sci Adv
Title: RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-8.
Volume: 9
Issue: 4
Pages: eadd6097
Publication
First Author: Schneider AT
Year: 2017
Journal: Cancer Cell
Title: RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer.
Volume: 31
Issue: 1
Pages: 94-109
Publication
First Author: Rickard JA
Year: 2014
Journal: Cell
Title: RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
Volume: 157
Issue: 5
Pages: 1175-88
Publication
First Author: Dondelinger Y
Year: 2017
Journal: Nat Cell Biol
Title: MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death.
Volume: 19
Issue: 10
Pages: 1237-1247
Publication
First Author: Filliol A
Year: 2016
Journal: Cell Death Dis
Title: RIPK1 protects from TNF-α-mediated liver damage during hepatitis.
Volume: 7
Issue: 11
Pages: e2462
Publication
First Author: Wong J
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-κB Activation.
Volume: 9
Issue: 2
Pages: 295-312
Publication
First Author: Dannappel M
Year: 2014
Journal: Nature
Title: RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis.
Volume: 513
Issue: 7516
Pages: 90-4
Publication
First Author: Menon MB
Year: 2017
Journal: Nat Cell Biol
Title: p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection.
Volume: 19
Issue: 10
Pages: 1248-1259
Publication
First Author: Dillon CP
Year: 2014
Journal: Cell
Title: RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3.
Volume: 157
Issue: 5
Pages: 1189-202
Publication
First Author: Wei R
Year: 2017
Journal: Genes Dev
Title: SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.
Volume: 31
Issue: 11
Pages: 1162-1176
Publication
First Author: Wong WW
Year: 2010
Journal: Cell Death Differ
Title: RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.
Volume: 17
Issue: 3
Pages: 482-7
Publication
First Author: Van TM
Year: 2017
Journal: J Clin Invest
Title: Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis.
Volume: 127
Issue: 7
Pages: 2662-2677
Publication
First Author: Takahashi N
Year: 2014
Journal: Nature
Title: RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.
Volume: 513
Issue: 7516
Pages: 95-9
Publication
First Author: Lafont E
Year: 2018
Journal: Nat Cell Biol
Title: TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation.
Volume: 20
Issue: 12
Pages: 1389-1399
Publication
First Author: Anderton H
Year: 2019
Journal: Cell Death Differ
Title: RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development.
Volume: 26
Issue: 5
Pages: 877-889
Publication
First Author: Ofengeim D
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: RIPK1 mediates a disease-associated microglial response in Alzheimer's disease.
Volume: 114
Issue: 41
Pages: E8788-E8797
Publication
First Author: Zhang X
Year: 2019
Journal: Nat Commun
Title: Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis.
Volume: 10
Issue: 1
Pages: 4158
Publication
First Author: Meng H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis.
Volume: 115
Issue: 9
Pages: E2001-E2009
Publication
First Author: Du J
Year: 2021
Journal: Nat Commun
Title: RIPK1 dephosphorylation and kinase activation by PPP1R3G/PP1γ promote apoptosis and necroptosis.
Volume: 12
Issue: 1
Pages: 7067
Publication
First Author: Zhang X
Year: 2019
Journal: Cell Death Dis
Title: RIPK1 can mediate apoptosis in addition to necroptosis during embryonic development.
Volume: 10
Issue: 3
Pages: 245
Publication
First Author: Tan H
Year: 2018
Journal: Cell Physiol Biochem
Title: MicroRNA-24-3p Attenuates Myocardial Ischemia/Reperfusion Injury by Suppressing RIPK1 Expression in Mice.
Volume: 51
Issue: 1
Pages: 46-62
Gene
Type: gene
Organism: human
Publication  
First Author: Hägglöf T
Year: 2023
Journal: Front Immunol
Title: RIPK1 deficiency prevents thymic NK1.1 expression and subsequent iNKT cell development.
Volume: 14
Pages: 1103591
Publication
First Author: Kearney CJ
Year: 2014
Journal: FEBS J
Title: RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis.
Volume: 281
Issue: 21
Pages: 4921-34
Publication
First Author: O'Donnell JA
Year: 2018
Journal: J Immunol
Title: Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
Volume: 200
Issue: 2
Pages: 737-748
Publication
First Author: Najjar M
Year: 2016
Journal: Immunity
Title: RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4.
Volume: 45
Issue: 1
Pages: 46-59
Publication
First Author: Moriwaki K
Year: 2022
Journal: Mucosal Immunol
Title: The scaffold-dependent function of RIPK1 in dendritic cells promotes injury-induced colitis.
Volume: 15
Issue: 1
Pages: 84-95
Publication  
First Author: Coornaert I
Year: 2021
Journal: Atherosclerosis
Title: Impact of myeloid RIPK1 gene deletion on atherogenesis in ApoE-deficient mice.
Volume: 322
Pages: 51-60
Publication
First Author: Schorn F
Year: 2023
Journal: EMBO J
Title: cIAPs control RIPK1 kinase activity-dependent and -independent cell death and tissue inflammation.
Volume: 42
Issue: 22
Pages: e113614
Publication      
First Author: Tu H
Year: 2021
Journal: J Immunol
Title: Linear Ubiquitination of RIPK1 on Lys 612 Regulates Systemic Inflammation via Preventing Cell Death.
Publication
First Author: Farooq M
Year: 2019
Journal: Cell Death Dis
Title: Depletion of RIPK1 in hepatocytes exacerbates liver damage in fulminant viral hepatitis.
Volume: 10
Issue: 1
Pages: 12
Publication
First Author: Geng J
Year: 2017
Journal: Nat Commun
Title: Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.
Volume: 8
Issue: 1
Pages: 359
Publication
First Author: Wang H
Year: 2021
Journal: Nat Commun
Title: NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation.
Volume: 12
Issue: 1
Pages: 4826
Publication
First Author: Cucolo L
Year: 2022
Journal: Immunity
Title: The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade.
Volume: 55
Issue: 4
Pages: 671-685.e10
Publication
First Author: Wang Y
Year: 2022
Journal: Cell Rep
Title: Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation.
Volume: 41
Issue: 1
Pages: 111434
Publication
First Author: Polykratis A
Year: 2014
Journal: J Immunol
Title: Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo.
Volume: 193
Issue: 4
Pages: 1539-1543
Publication
First Author: Dondelinger Y
Year: 2019
Journal: Nat Commun
Title: Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation.
Volume: 10
Issue: 1
Pages: 1729
Publication
First Author: Lule S
Year: 2021
Journal: J Cereb Blood Flow Metab
Title: Cell-specific activation of RIPK1 and MLKL after intracerebral hemorrhage in mice.
Volume: 41
Issue: 7
Pages: 1623-1633
Publication
First Author: Dowling JP
Year: 2019
Journal: Nat Commun
Title: TRADD regulates perinatal development and adulthood survival in mice lacking RIPK1 and RIPK3.
Volume: 10
Issue: 1
Pages: 705
Publication
First Author: Liccardi G
Year: 2019
Journal: Mol Cell
Title: RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation.
Volume: 73
Issue: 3
Pages: 413-428.e7
Publication
First Author: Newton K
Year: 2019
Journal: Nature
Title: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
Volume: 574
Issue: 7778
Pages: 428-431
Publication
First Author: Roderick JE
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis.
Volume: 111
Issue: 40
Pages: 14436-41
Publication  
First Author: Snyder AG
Year: 2019
Journal: Sci Immunol
Title: Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity.
Volume: 4
Issue: 36
Publication
First Author: Zhang T
Year: 2023
Journal: Nat Cell Biol
Title: Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Volume: 25
Issue: 7
Pages: 950-962
Publication
First Author: Li X
Year: 2020
Journal: Nat Commun
Title: Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners.
Volume: 11
Issue: 1
Pages: 6364
Publication
First Author: Cachón-González MB
Year: 2021
Journal: Hum Mol Genet
Title: Expression of Ripk1 and DAM genes correlates with severity and progression of Krabbe disease.
Volume: 30
Issue: 22
Pages: 2082-2099
Publication
First Author: Tan S
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Hepatocyte-specific TAK1 deficiency drives RIPK1 kinase-dependent inflammation to promote liver fibrosis and hepatocellular carcinoma.
Volume: 117
Issue: 25
Pages: 14231-14242
Publication    
First Author: Iorga A
Year: 2021
Journal: J Biol Chem
Title: Interaction of RIPK1 and A20 modulates MAPK signaling in murine acetaminophen toxicity.
Pages: 100300
Publication
First Author: Di Grazia A
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: The Fragile X Mental Retardation Protein Regulates RIPK1 and Colorectal Cancer Resistance to Necroptosis.
Volume: 11
Issue: 2
Pages: 639-658
Publication
First Author: Yatim N
Year: 2015
Journal: Science
Title: RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.
Volume: 350
Issue: 6258
Pages: 328-34
Publication
First Author: Kondylis V
Year: 2015
Journal: Cancer Cell
Title: NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis.
Volume: 28
Issue: 5
Pages: 582-598
Publication
First Author: Dziedzic SA
Year: 2018
Journal: Nat Cell Biol
Title: ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC.
Volume: 20
Issue: 1
Pages: 58-68
Publication  
First Author: Chen KW
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling.
Volume: 118
Issue: 28
Publication
First Author: Tang Y
Year: 2019
Journal: Nat Commun
Title: K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation.
Volume: 10
Issue: 1
Pages: 4157
Publication
First Author: Karunakaran D
Year: 2020
Journal: Nat Metab
Title: RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice.
Volume: 2
Issue: 10
Pages: 1113-1125
Publication
First Author: Saleh D
Year: 2017
Journal: J Immunol
Title: Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide.
Volume: 198
Issue: 11
Pages: 4435-4447
Publication
First Author: Kist M
Year: 2021
Journal: Cell Death Differ
Title: Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death.
Volume: 28
Issue: 3
Pages: 985-1000
Publication  
First Author: Müller K
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging.
Volume: 118
Issue: 12
Publication
First Author: Webb LV
Year: 2019
Journal: Immunity
Title: Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB.
Volume: 50
Issue: 2
Pages: 348-361.e4
Publication  
First Author: Qin X
Year: 2020
Journal: Biochem Pharmacol
Title: The Bcr-Abl inhibitor GNF-7 inhibits necroptosis and ameliorates acute kidney injury by targeting RIPK1 and RIPK3 kinases.
Volume: 177
Pages: 113947
Publication
First Author: Zhang Y
Year: 2021
Journal: PLoS Biol
Title: A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5.
Volume: 19
Issue: 8
Pages: e3001304
Publication
First Author: Shutinoski B
Year: 2016
Journal: Cell Death Differ
Title: K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.
Volume: 23
Issue: 10
Pages: 1628-37
Publication  
First Author: Malireddi RKS
Year: 2020
Journal: J Exp Med
Title: Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease.
Volume: 217
Issue: 3
Publication
First Author: Liu S
Year: 2018
Journal: Cell Death Dis
Title: Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis.
Volume: 9
Issue: 5
Pages: 476
Publication
First Author: Lee CS
Year: 2023
Journal: Cell Death Differ
Title: IKK-mediated TRAF6 and RIPK1 interaction stifles cell death complex assembly leading to the suppression of TNF-α-induced cell death.
Volume: 30
Issue: 6
Pages: 1575-1584
Publication
First Author: Krishna-Subramanian S
Year: 2019
Journal: Cell Death Differ
Title: RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury.
Volume: 26
Issue: 12
Pages: 2710-2726
Publication
First Author: Amin P
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis.
Volume: 115
Issue: 26
Pages: E5944-E5953
Publication
First Author: Martin-Sanchez D
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: TWEAK and RIPK1 mediate a second wave of cell death during AKI.
Volume: 115
Issue: 16
Pages: 4182-4187
Publication
First Author: Verboom L
Year: 2020
Journal: Cell Rep
Title: OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis.
Volume: 30
Issue: 7
Pages: 2237-2247.e6
Publication
First Author: Wehn AC
Year: 2021
Journal: Acta Neuropathol Commun
Title: RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury.
Volume: 9
Issue: 1
Pages: 138
Publication
First Author: Hofmann K
Year: 1999
Journal: Cell Mol Life Sci
Title: The modular nature of apoptotic signaling proteins.
Volume: 55
Issue: 8-9
Pages: 1113-28
Publication
First Author: Peterson LW
Year: 2017
Journal: J Exp Med
Title: RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense.
Volume: 214
Issue: 11
Pages: 3171-3182
Publication
First Author: Zhang T
Year: 2023
Journal: Science
Title: Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1.
Volume: 380
Issue: 6652
Pages: 1372-1380
Publication
First Author: Zelic M
Year: 2018
Journal: J Clin Invest
Title: RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome.
Volume: 128
Issue: 5
Pages: 2064-2075
Publication
First Author: Lule S
Year: 2017
Journal: Stroke
Title: Genetic Inhibition of Receptor Interacting Protein Kinase-1 Reduces Cell Death and Improves Functional Outcome After Intracerebral Hemorrhage in Mice.
Volume: 48
Issue: 9
Pages: 2549-2556
Publication    
First Author: Li D
Year: 2017
Journal: Elife
Title: RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system.
Volume: 6
Publication
First Author: Hoste E
Year: 2019
Journal: Cell Rep
Title: Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation.
Volume: 29
Issue: 9
Pages: 2689-2701.e4
Publication
First Author: Laurien L
Year: 2020
Journal: Nat Commun
Title: Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation.
Volume: 11
Issue: 1
Pages: 1747
Publication
First Author: Kesavardhana S
Year: 2020
Journal: J Biol Chem
Title: The Zα2 domain of ZBP1 is a molecular switch regulating influenza-induced PANoptosis and perinatal lethality during development.
Volume: 295
Issue: 24
Pages: 8325-8330
Publication
First Author: Li X
Year: 2022
Journal: Cell Death Differ
Title: Caspase-8 auto-cleavage regulates programmed cell death and collaborates with RIPK3/MLKL to prevent lymphopenia.
Volume: 29
Issue: 8
Pages: 1500-1512
Publication
First Author: Hou S
Year: 2024
Journal: Mol Cell
Title: PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis.
Volume: 84
Issue: 5
Pages: 938-954.e8
Publication  
First Author: Mifflin L
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis.
Volume: 118
Issue: 13
Publication  
First Author: Devos M
Year: 2020
Journal: J Exp Med
Title: Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation.
Volume: 217
Issue: 7
Publication
First Author: Tummers B
Year: 2020
Journal: Immunity
Title: Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis.
Volume: 52
Issue: 6
Pages: 994-1006.e8
Publication
First Author: Speir M
Year: 2020
Journal: Nat Immunol
Title: Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.
Volume: 21
Issue: 1
Pages: 54-64