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Search results 1 to 100 out of 780 for Ripk3

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Daniels BP
Year: 2017
Journal: Cell
Title: RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation.
Volume: 169
Issue: 2
Pages: 301-313.e11
Publication
First Author: Amini P
Year: 2016
Journal: Eur J Immunol
Title: NET formation can occur independently of RIPK3 and MLKL signaling.
Volume: 46
Issue: 1
Pages: 178-84
Publication  
First Author: Imamura M
Year: 2018
Journal: JCI Insight
Title: RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase.
Volume: 3
Issue: 3
Publication  
First Author: Sureshbabu A
Year: 2018
Journal: JCI Insight
Title: RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction.
Volume: 3
Issue: 11
Publication
First Author: Vitner EB
Year: 2014
Journal: Nat Med
Title: RIPK3 as a potential therapeutic target for Gaucher's disease.
Volume: 20
Issue: 2
Pages: 204-8
Publication
First Author: Bozec D
Year: 2016
Journal: Oncotarget
Title: Critical function of the necroptosis adaptor RIPK3 in protecting from intestinal tumorigenesis.
Volume: 7
Issue: 29
Pages: 46384-46400
Publication
First Author: Gao S
Year: 2021
Journal: Angiogenesis
Title: RIPK3 modulates growth factor receptor expression in endothelial cells to support angiogenesis.
Volume: 24
Issue: 3
Pages: 519-531
Publication
First Author: Lindman M
Year: 2023
Journal: PLoS Pathog
Title: RIPK3 promotes brain region-specific interferon signaling and restriction of tick-borne flavivirus infection.
Volume: 19
Issue: 11
Pages: e1011813
Publication
First Author: Moriwaki K
Year: 2014
Journal: Immunity
Title: The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair.
Volume: 41
Issue: 4
Pages: 567-78
Publication  
First Author: Gautheron J
Year: 2016
Journal: Nat Commun
Title: The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance.
Volume: 7
Pages: 11869
Publication
First Author: Zhao Q
Year: 2017
Journal: Cell Rep
Title: RIPK3 Mediates Necroptosis during Embryonic Development and Postnatal Inflammation in Fadd-Deficient Mice.
Volume: 19
Issue: 4
Pages: 798-808
Publication
First Author: Patton T
Year: 2023
Journal: Cell Death Dis
Title: RIPK3 controls MAIT cell accumulation during development but not during infection.
Volume: 14
Issue: 2
Pages: 111
Publication
First Author: Shi Y
Year: 2020
Journal: Sci Rep
Title: RIPK3 blockade attenuates tubulointerstitial fibrosis in a mouse model of diabetic nephropathy.
Volume: 10
Issue: 1
Pages: 10458
Publication
First Author: Cao M
Year: 2019
Journal: Cell Death Differ
Title: Dectin-1-induced RIPK1 and RIPK3 activation protects host against Candida albicans infection.
Volume: 26
Issue: 12
Pages: 2622-2636
Publication
First Author: Wu XL
Year: 2021
Journal: Nat Commun
Title: The amyloid structure of mouse RIPK3 (receptor interacting protein kinase 3) in cell necroptosis.
Volume: 12
Issue: 1
Pages: 1627
Publication
First Author: Shutinoski B
Year: 2020
Journal: Microbes Infect
Title: Ripk3 licenced protection against microbial infection in the absence of Caspase1-11 inflammasome.
Volume: 22
Issue: 1
Pages: 40-45
Publication
First Author: Najjar M
Year: 2016
Journal: Immunity
Title: RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4.
Volume: 45
Issue: 1
Pages: 46-59
Publication
First Author: Newton K
Year: 2014
Journal: Science
Title: Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis.
Volume: 343
Issue: 6177
Pages: 1357-60
Publication
First Author: Liu Z
Year: 2021
Journal: Immunity
Title: A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation.
Volume: 54
Issue: 2
Pages: 247-258.e7
Publication
First Author: Shi Y
Year: 2020
Journal: FASEB J
Title: RIPK3 blockade attenuates kidney fibrosis in a folic acid model of renal injury.
Volume: 34
Issue: 8
Pages: 10286-10298
Publication  
First Author: Zhang J
Year: 2022
Journal: Oxid Med Cell Longev
Title: Ca2+/Calmodulin-Dependent Protein Kinase II Regulation by Inhibitor of RIPK3 Protects against Cardiac Hypertrophy.
Volume: 2022
Pages: 7941374
Publication
First Author: Nogusa S
Year: 2016
Journal: Cell Host Microbe
Title: RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.
Volume: 20
Issue: 1
Pages: 13-24
Publication
First Author: Sai K
Year: 2019
Journal: J Cell Biol
Title: Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing.
Volume: 218
Issue: 6
Pages: 1994-2005
Publication
First Author: Moriwaki K
Year: 2017
Journal: Cell Rep
Title: Distinct Kinase-Independent Role of RIPK3 in CD11c+ Mononuclear Phagocytes in Cytokine-Induced Tissue Repair.
Volume: 18
Issue: 10
Pages: 2441-2451
Publication
First Author: Onizawa M
Year: 2015
Journal: Nat Immunol
Title: The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis.
Volume: 16
Issue: 6
Pages: 618-27
Publication  
First Author: Moerke C
Year: 2019
Journal: Front Cell Dev Biol
Title: Combined Knockout of RIPK3 and MLKL Reveals Unexpected Outcome in Tissue Injury and Inflammation.
Volume: 7
Pages: 19
Publication    
First Author: Li D
Year: 2021
Journal: Elife
Title: A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2α-induced corpus luteum regression.
Volume: 10
Publication
First Author: Matsuzawa Y
Year: 2015
Journal: Biochem Biophys Res Commun
Title: RIPK3 regulates p62-LC3 complex formation via the caspase-8-dependent cleavage of p62.
Volume: 456
Issue: 1
Pages: 298-304
Publication  
First Author: Snyder AG
Year: 2019
Journal: Sci Immunol
Title: Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity.
Volume: 4
Issue: 36
Publication  
First Author: Zhu P
Year: 2018
Journal: Redox Biol
Title: Ripk3 promotes ER stress-induced necroptosis in cardiac IR injury: A mechanism involving calcium overload/XO/ROS/mPTP pathway.
Volume: 16
Pages: 157-168
Publication
First Author: Wu L
Year: 2021
Journal: Cell Death Dis
Title: Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosis.
Volume: 12
Issue: 11
Pages: 1064
Publication
First Author: Höckendorf U
Year: 2016
Journal: Cancer Cell
Title: RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells.
Volume: 30
Issue: 1
Pages: 75-91
Publication
First Author: Günther C
Year: 2016
Journal: J Clin Invest
Title: The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis.
Volume: 126
Issue: 11
Pages: 4346-4360
Publication  
First Author: Colijn S
Year: 2020
Journal: Dis Model Mech
Title: Cell-specific and athero-protective roles for RIPK3 in a murine model of atherosclerosis.
Volume: 13
Issue: 1
Publication
First Author: Downey J
Year: 2017
Journal: PLoS Pathog
Title: RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection.
Volume: 13
Issue: 4
Pages: e1006326
Publication
First Author: Colijn S
Year: 2020
Journal: Cell Death Differ
Title: The NuRD chromatin-remodeling complex enzyme CHD4 prevents hypoxia-induced endothelial Ripk3 transcription and murine embryonic vascular rupture.
Volume: 27
Issue: 2
Pages: 618-631
Publication  
First Author: Lawlor KE
Year: 2015
Journal: Nat Commun
Title: RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.
Volume: 6
Pages: 6282
Publication
First Author: Saleh D
Year: 2017
Journal: J Immunol
Title: Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide.
Volume: 198
Issue: 11
Pages: 4435-4447
Publication
First Author: Someda M
Year: 2020
Journal: Cell Death Differ
Title: Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis.
Volume: 27
Issue: 5
Pages: 1539-1553
Publication  
First Author: Qin X
Year: 2020
Journal: Biochem Pharmacol
Title: The Bcr-Abl inhibitor GNF-7 inhibits necroptosis and ameliorates acute kidney injury by targeting RIPK1 and RIPK3 kinases.
Volume: 177
Pages: 113947
Publication
First Author: Sharma D
Year: 2020
Journal: J Immunol
Title: RIPK3 Promotes Mefv Expression and Pyrin Inflammasome Activation via Modulation of mTOR Signaling.
Volume: 205
Issue: 10
Pages: 2778-2785
Publication  
First Author: Mukherjee N
Year: 2024
Journal: Mol Metab
Title: RIPK3 promotes islet amyloid-induced β-cell loss and glucose intolerance in a humanized mouse model of type 2 diabetes.
Volume: 80
Pages: 101877
Publication
First Author: Alvarez-Diaz S
Year: 2016
Journal: Immunity
Title: The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis.
Volume: 45
Issue: 3
Pages: 513-526
Publication
First Author: Thijssen R
Year: 2020
Journal: Cell Death Differ
Title: Loss of RIPK3 does not impact MYC-driven lymphomagenesis or chemotherapeutic drug-induced killing of malignant lymphoma cells.
Volume: 27
Issue: 8
Pages: 2531-2533
Publication
First Author: Nogusa S
Year: 2016
Journal: PLoS One
Title: RIPK3 Is Largely Dispensable for RIG-I-Like Receptor- and Type I Interferon-Driven Transcriptional Responses to Influenza A Virus in Murine Fibroblasts.
Volume: 11
Issue: 7
Pages: e0158774
Publication
First Author: Liu S
Year: 2018
Journal: Cell Death Dis
Title: Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis.
Volume: 9
Issue: 5
Pages: 476
Publication
First Author: Daniels BP
Year: 2019
Journal: Immunity
Title: The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons.
Volume: 50
Issue: 1
Pages: 64-76.e4
Publication
First Author: Newton K
Year: 2016
Journal: Cell Death Differ
Title: RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.
Volume: 23
Issue: 9
Pages: 1565-76
Publication
First Author: Wehn AC
Year: 2021
Journal: Acta Neuropathol Commun
Title: RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury.
Volume: 9
Issue: 1
Pages: 138
Publication  
First Author: Dermentzaki G
Year: 2019
Journal: eNeuro
Title: Deletion of Ripk3 Prevents Motor Neuron Death In Vitro but not In Vivo.
Volume: 6
Issue: 1
Publication
First Author: Ofengeim D
Year: 2015
Journal: Cell Rep
Title: Activation of necroptosis in multiple sclerosis.
Volume: 10
Issue: 11
Pages: 1836-49
Publication  
First Author: Zhu P
Year: 2022
Journal: Front Cardiovasc Med
Title: Receptor-Interacting Protein Kinase 3 Suppresses Mitophagy Activation via the Yes-Associated Protein/Transcription Factor EB Pathways in Septic Cardiomyopathy.
Volume: 9
Pages: 856041
Publication
First Author: Oka K
Year: 2022
Journal: Commun Biol
Title: Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats.
Volume: 5
Issue: 1
Pages: 287
Publication
First Author: Thapa RJ
Year: 2016
Journal: Cell Host Microbe
Title: DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death.
Volume: 20
Issue: 5
Pages: 674-681
Publication    
First Author: Li D
Year: 2020
Journal: Elife
Title: Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3.
Volume: 9
Publication
First Author: Jouan-Lanhouet S
Year: 2012
Journal: Cell Death Differ
Title: TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation.
Volume: 19
Issue: 12
Pages: 2003-14
Publication
First Author: Pavlosky A
Year: 2014
Journal: Am J Transplant
Title: RIPK3-mediated necroptosis regulates cardiac allograft rejection.
Volume: 14
Issue: 8
Pages: 1778-90
Publication  
First Author: Stutz MD
Year: 2018
Journal: Front Immunol
Title: Is Receptor-Interacting Protein Kinase 3 a Viable Therapeutic Target for Mycobacterium tuberculosis Infection?
Volume: 9
Pages: 1178
Publication
First Author: Yan G
Year: 2018
Journal: Cancer Res
Title: A RIPK3-PGE2 Circuit Mediates Myeloid-Derived Suppressor Cell-Potentiated Colorectal Carcinogenesis.
Volume: 78
Issue: 19
Pages: 5586-5599
Publication
First Author: Morgan JE
Year: 2018
Journal: Nat Commun
Title: Necroptosis mediates myofibre death in dystrophin-deficient mice.
Volume: 9
Issue: 1
Pages: 3655
Publication
First Author: Godwin A
Year: 2015
Journal: PLoS One
Title: Receptor-Interacting Protein Kinase 3 Deficiency Delays Cutaneous Wound Healing.
Volume: 10
Issue: 10
Pages: e0140514
Publication
First Author: Sharma A
Year: 2014
Journal: Crit Care
Title: Receptor-interacting protein kinase 3 deficiency inhibits immune cell infiltration and attenuates organ injury in sepsis.
Volume: 18
Issue: 4
Pages: R142
Publication  
First Author: Kang YJ
Year: 2015
Journal: Nat Commun
Title: Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.
Volume: 6
Pages: 8371
Publication
First Author: Torii S
Year: 2020
Journal: Nat Commun
Title: Identification of a phosphorylation site on Ulk1 required for genotoxic stress-induced alternative autophagy.
Volume: 11
Issue: 1
Pages: 1754
Publication
First Author: Duprez L
Year: 2011
Journal: Immunity
Title: RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome.
Volume: 35
Issue: 6
Pages: 908-18
Publication    
First Author: Li D
Year: 2017
Journal: Elife
Title: RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system.
Volume: 6
Publication
First Author: Desai J
Year: 2016
Journal: Eur J Immunol
Title: PMA and crystal-induced neutrophil extracellular trap formation involves RIPK1-RIPK3-MLKL signaling.
Volume: 46
Issue: 1
Pages: 223-9
Publication
First Author: Kitur K
Year: 2016
Journal: Cell Rep
Title: Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling.
Volume: 16
Issue: 8
Pages: 2219-2230
Publication
First Author: Wang S
Year: 2021
Journal: Stem Cell Reports
Title: Non-muscle myosin heavy chain 9 maintains intestinal homeostasis by preventing epithelium necroptosis and colitis adenoma formation.
Volume: 16
Issue: 5
Pages: 1290-1301
Publication
First Author: Zhang X
Year: 2016
Journal: Cell Rep
Title: MLKL and FADD Are Critical for Suppressing Progressive Lymphoproliferative Disease and Activating the NLRP3 Inflammasome.
Volume: 16
Issue: 12
Pages: 3247-3259
Publication
First Author: Tanzer MC
Year: 2015
Journal: Biochem J
Title: Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop.
Volume: 471
Issue: 2
Pages: 255-65
Publication
First Author: Seo J
Year: 2016
Journal: Nat Cell Biol
Title: CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3.
Volume: 18
Issue: 3
Pages: 291-302
Publication
First Author: Yang J
Year: 2018
Journal: Cereb Cortex
Title: RIPK3/MLKL-Mediated Neuronal Necroptosis Modulates the M1/M2 Polarization of Microglia/Macrophages in the Ischemic Cortex.
Volume: 28
Issue: 7
Pages: 2622-2635
Publication
First Author: Rodriguez DA
Year: 2016
Journal: Cell Death Differ
Title: Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis.
Volume: 23
Issue: 1
Pages: 76-88
Publication
First Author: Li X
Year: 2019
Journal: Immunity
Title: O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.
Volume: 50
Issue: 3
Pages: 576-590.e6
Publication
First Author: Pajuelo D
Year: 2018
Journal: Cell Rep
Title: NAD+ Depletion Triggers Macrophage Necroptosis, a Cell Death Pathway Exploited by Mycobacterium tuberculosis.
Volume: 24
Issue: 2
Pages: 429-440
Publication  
First Author: Mulay SR
Year: 2016
Journal: Nat Commun
Title: Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis.
Volume: 7
Pages: 10274
Publication
First Author: Patel R
Year: 2017
Journal: Cell Death Differ
Title: Culling of APCs by inflammatory cell death pathways restricts TIM3 and PD-1 expression and promotes the survival of primed CD8 T cells.
Volume: 24
Issue: 11
Pages: 1900-1911
Publication
First Author: Najafov A
Year: 2021
Journal: Mol Cell
Title: RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.
Volume: 81
Issue: 2
Pages: 370-385.e7
Publication
First Author: Naito MG
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke.
Volume: 117
Issue: 9
Pages: 4959-4970
Publication
First Author: Kang TB
Year: 2013
Journal: Immunity
Title: Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.
Volume: 38
Issue: 1
Pages: 27-40
Publication    
First Author: Kumari S
Year: 2014
Journal: Elife
Title: Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis.
Volume: 3
Publication
First Author: Boytard L
Year: 2020
Journal: Nat Commun
Title: Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages.
Volume: 11
Issue: 1
Pages: 4311
Publication
First Author: Guo H
Year: 2018
Journal: Cell Death Dis
Title: Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1.
Volume: 9
Issue: 8
Pages: 816
Publication
First Author: Feng Y
Year: 2018
Journal: J Immunol
Title: Remarkably Robust Antiviral Immune Response despite Combined Deficiency in Caspase-8 and RIPK3.
Volume: 201
Issue: 8
Pages: 2244-2255
Publication
First Author: Roderick JE
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis.
Volume: 111
Issue: 40
Pages: 14436-41
Publication
First Author: Petersen SL
Year: 2015
Journal: Cell Death Differ
Title: TRAF2 is a biologically important necroptosis suppressor.
Volume: 22
Issue: 11
Pages: 1846-57
Publication
First Author: Shutinoski B
Year: 2016
Journal: Cell Death Differ
Title: K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.
Volume: 23
Issue: 10
Pages: 1628-37
Publication
First Author: Tam VC
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: PPARα exacerbates necroptosis, leading to increased mortality in postinfluenza bacterial superinfection.
Volume: 117
Issue: 27
Pages: 15789-15798
Publication
First Author: Fuchslocher Chico J
Year: 2018
Journal: Oncotarget
Title: The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis.
Volume: 9
Issue: 16
Pages: 12941-12958