Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
RING finger protein 152 (RNF152) has E3 ligase activity involved in lysosome-related apoptosis []. It is a negative regulator of the mTORC1 pathway by targeting RagA for K63-linked ubiquitination []. |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Deng L |
Year: |
2015 |
Journal: |
Mol Cell |
Title: |
The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation. |
Volume: |
58 |
Issue: |
5 |
Pages: |
804-18 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
203
|
Fragment?: |
false |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 12.5 |
Image: |
Rnf152 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Rnf152 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 14.5 |
Image: |
Rnf152 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Rnf152 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271220 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 12.5 |
Image: |
Rnf152 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Rnf152 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271222 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 14.5 |
Image: |
Rnf152 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Rnf152 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754320 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 12.5 |
Image: |
Rnf152 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Rnf152 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754322 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 14.5 |
Image: |
Rnf152 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Rnf152 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753720 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 12.5 |
Image: |
Rnf152 - E12.5 |
Note: |
There is strong staining in the MZ of the AVH, moderate staining in the PVH nucleus and weak staining in the ventral POA. Staining is either absent or ubiquitous in the MZ of the dorsal POA, the VMH and ARH nuclei and anterior and posterior IDs. |
Specimen Label: |
Rnf152 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753722 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 14.5 |
Image: |
Rnf152 - E14.5 |
Note: |
There is weak staining in the mantle zone of the PVH and VMH nuclei. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the ARH nucleus, the AVH and anterior and posterior IDs. |
Specimen Label: |
Rnf152 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691319 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 11.5 |
Image: |
Rnf152 - E11.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex and the ganglionic eminences. |
Specimen Label: |
Rnf152 - E11.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271820 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 12.5 |
Image: |
Rnf152 - E12.5 |
Note: |
There is weak staining in the mantle zone of the supramam zone. Staining is either absent or ubiquitous in the mantle zone of the premam and mam zones and the TT. |
Specimen Label: |
Rnf152 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271824 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 16.5 |
Image: |
Rnf152 - E16.5 |
Note: |
There is moderate staining in the mantle zone of the mam zone and weak staining in the supramam zone. Staining is either absent or ubiquitous in the mantle zone of the premam zone. |
Specimen Label: |
Rnf152 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1690819 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 11.5 |
Image: |
Rnf152 - E11.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT. |
Specimen Label: |
Rnf152 - E11.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753922 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 14.5 |
Image: |
Rnf152 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Rnf152 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753924 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 16.5 |
Image: |
Rnf152 - E16.5 |
Note: |
There is weak staining in the ventricular zone of the DMH and VMH nuclei. Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, SCH and ARH nuclei, the AVH, the DAH and the PH. |
Specimen Label: |
Rnf152 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754720 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 12.5 |
Image: |
Rnf152 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Rnf152 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 14.5 |
Image: |
Rnf152 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Rnf152 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271020 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 12.5 |
Image: |
Rnf152 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT. |
Specimen Label: |
Rnf152 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271022 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 14.5 |
Image: |
Rnf152 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT. |
Specimen Label: |
Rnf152 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266520 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 12.5 |
Image: |
Rnf152 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences. |
Specimen Label: |
Rnf152 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266522 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 14.5 |
Image: |
Rnf152 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences. |
Specimen Label: |
Rnf152 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1690619 |
Pattern: |
Non-Uniform |
Stage: |
TS19 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 11.5 |
Image: |
Rnf152 - E11.5 |
Note: |
There is moderate staining in the MZ of the prethalamus. Staining is either absent or ubiquitous in the MZ of the dorsal thalamus, dorsal & ventral POAs, the PVH, VMH & ARH nuclei, the AVH, anterior & posterior IDs, premam, mam & supramam zones & the TT. |
Specimen Label: |
Rnf152 - E11.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754120 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 12.5 |
Image: |
Rnf152 - E12.5 |
Note: |
There is strong staining in the mantle zone of the dorsal thalamus and weak staining in the prethalamus. |
Specimen Label: |
Rnf152 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754124 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 16.5 |
Image: |
Rnf152 - E16.5 |
Note: |
There is moderate staining in the mantle zone of the dorsal thalamus and weak staining in the prethalamus. |
Specimen Label: |
Rnf152 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271124 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 16.5 |
Image: |
Rnf152 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Rnf152 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271224 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 16.5 |
Image: |
Rnf152 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Rnf152 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754324 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 16.5 |
Image: |
Rnf152 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Rnf152 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753724 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 16.5 |
Image: |
Rnf152 - E16.5 |
Note: |
There is weak staining in the mantle zone of the dorsal and ventral POAs, the AVH, the DAH and the VMH nucleus. Staining is either absent or ubiquitous in the mantle zone of the PVH, SCH, DMH and ARH nuclei and the PH. |
Specimen Label: |
Rnf152 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271822 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 14.5 |
Image: |
Rnf152 - E14.5 |
Note: |
There is weak staining in the mantle zone of the supramam zone. Staining is either absent or ubiquitous in the mantle zone of the premam and mam zones and the TT. |
Specimen Label: |
Rnf152 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753920 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 12.5 |
Image: |
Rnf152 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Rnf152 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691119 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 11.5 |
Image: |
Rnf152 - E11.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences. |
Specimen Label: |
Rnf152 - E11.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754724 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 16.5 |
Image: |
Rnf152 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Rnf152 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271024 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 16.5 |
Image: |
Rnf152 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones. |
Specimen Label: |
Rnf152 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266524 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 16.5 |
Image: |
Rnf152 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences. |
Specimen Label: |
Rnf152 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442685 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754122 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450832 |
Age: |
embryonic day 14.5 |
Image: |
Rnf152 - E14.5 |
Note: |
There is strong staining in the mantle zone of the dorsal thalamus and weak staining in the prethalamus. |
Specimen Label: |
Rnf152 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang S |
Year: |
2010 |
Journal: |
Protein Cell |
Title: |
RNF152, a novel lysosome localized E3 ligase with pro-apoptotic activities. |
Volume: |
1 |
Issue: |
7 |
Pages: |
656-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiong MG |
Year: |
2020 |
Journal: |
EMBO Rep |
Title: |
RNF152 positively regulates TLR/IL-1R signaling by enhancing MyD88 oligomerization. |
Volume: |
21 |
Issue: |
3 |
Pages: |
e48860 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu Y |
Year: |
2018 |
Journal: |
PLoS One |
Title: |
Sec16A, a key protein in COPII vesicle formation, regulates the stability and localization of the novel ubiquitin ligase RNF183. |
Volume: |
13 |
Issue: |
1 |
Pages: |
e0190407 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Publication |
First Author: |
Deng L |
Year: |
2019 |
Journal: |
Cell Res |
Title: |
Ubiquitination of Rheb governs growth factor-induced mTORC1 activation. |
Volume: |
29 |
Issue: |
2 |
Pages: |
136-150 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Shimogori T |
Year: |
2010 |
Journal: |
Nat Neurosci |
Title: |
A genomic atlas of mouse hypothalamic development. |
Volume: |
13 |
Issue: |
6 |
Pages: |
767-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
E3 ubiquitin-protein ligase RNF152 |
Type: |
chain |
End: |
203 |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
RNF152 positively regulates TLR/IL-1R signaling by enhancing MyD88 oligomerization. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the C-terminal domain of the E3 ubiquitin ligase RNF152. This hydrophobic transmembrane domain is responsible for the lysosomal localisation of the protein as well as its ubiquitination activity. RNF152 polyubiquitinates several proteins and itself, which leads to proteasome degradation. It has been shown that this protein has also pro-apoptotic activity, dependent on its RING finger and transmembrane domains []. In addition, the transmembrane domain of RNF152 is necessary for negative regulation of the mTORC1 pathway in an amino-acid-sensitive manner, as it mediates RNF152-RagA interaction and RagA ubiquitination []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Kadoya M |
Year: |
2019 |
Journal: |
Front Neurosci |
Title: |
Negative Regulation of mTOR Signaling Restricts Cell Proliferation in the Floor Plate. |
Volume: |
13 |
|
Pages: |
1022 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|