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  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
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Search results 1 to 80 out of 80 for Rnls

0.045s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
55328 | RNLS
Type: gene
Organism: human
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Gene
361751 | Rnls
Type: gene
Organism: rat
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Gene
450581 | RNLS
Type: gene
Organism: chimpanzee
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Gene
610448 | RNLS
Type: gene
Organism: dog, domestic
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Gene
534778 | RNLS
Type: gene
Organism: cattle
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Gene
423674 | RNLS
Type: gene
Organism: chicken
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Gene
436880 | rnls
Type: gene
Organism: zebrafish
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Gene
708585 | RNLS
Type: gene
Organism: macaque, rhesus
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Gene
100037883 | rnls
Type: gene
Organism: frog, western clawed
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Polymorphic Pseudogene
MGI:1915045 | Rnls
Type: polymorphic_pseudogene
Organism: mouse, laboratory
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Protein Domain
IPR040174 | RNLS
Type: Family
Description: Renalase is a FAD-dependent amine oxidase that catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)+, activity that functions as an intracellular detoxification mechanism which alleviates inhibition of dehydrogenases by these compounds [, ]. In humans it is highly expressed in the kidneys and heart. It has been linked to chronic kidney disease and cardiovascular disease, and may serve as a potential drug target [].
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Protein
A7RDN6
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
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Protein
E9Q243
Organism: Mus musculus/domesticus
Length: 182  
Fragment?: false
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Protein
A0A0R4J156
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: false
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Publication
17385068 | -
First Author: Boomsma F
Year: 2007
Journal: J Neural Transm (Vienna)
Title: Renalase, a catecholamine-metabolising enzyme?
Volume: 114
Issue: 6
Pages: 775-6
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Publication
32916539 | -
 
First Author: Li Y
Year: 2020
Journal: Biomed Pharmacother
Title: Roles and mechanisms of renalase in cardiovascular disease: A promising therapeutic target.
Volume: 131
Pages: 110712
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Publication
28558965 | -
 
First Author: Moran GR
Year: 2017
Journal: Arch Biochem Biophys
Title: The enzyme: Renalase.
Volume: 632
Pages: 66-76
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Publication
36588579 | J:340675
 
First Author: Wang Y
Year: 2022
Journal: Front Cardiovasc Med
Title: Cardiac-specific renalase overexpression alleviates CKD-induced pathological cardiac remodeling in mice.
Volume: 9
Pages: 1061146
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Publication
27197188 | J:232785
First Author: Hollander L
Year: 2016
Journal: Cancer Res
Title: Renalase Expression by Melanoma and Tumor-Associated Macrophages Promotes Tumor Growth through a STAT3-Mediated Mechanism.
Volume: 76
Issue: 13
Pages: 3884-94
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Publication
35219026 | J:334039
 
First Author: Guo X
Year: 2022
Journal: Eur J Cancer
Title: Inhibition of renalase drives tumour rejection by promoting T cell activation.
Volume: 165
Pages: 81-96
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Protein Coding Gene
MGP_CAROLIEiJ_G0022880 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025044 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025021 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024989 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025020 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024776 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Polymorphic Pseudogene
MGI_C57BL6J_1915045 | -
Type: polymorphic_pseudogene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025461 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024247 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0024754 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024886 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024848 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024971 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025516 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023995 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024313 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014373 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023799 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
21178975 | J:186878
First Author: Wu Y
Year: 2011
Journal: Kidney Int
Title: Renalase deficiency aggravates ischemic myocardial damage.
Volume: 79
Issue: 8
Pages: 853-60
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Publication
23863468 | J:200928
First Author: Sizova D
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Renalase regulates renal dopamine and phosphate metabolism.
Volume: 305
Issue: 6
Pages: F839-44
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Publication
25411385 | J:280080
First Author: Quelhas-Santos J
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Renalase regulates peripheral and central dopaminergic activities.
Volume: 308
Issue: 2
Pages: F84-91
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Publication
33495844 | J:309508
 
First Author: Tokinoya K
Year: 2021
Journal: Mol Med Rep
Title: Effects of renalase deficiency on liver fibrosis markers in a nonalcoholic steatohepatitis mouse model.
Volume: 23
Issue: 3
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Publication
32741114 | J:313540
First Author: Tokinoya K
Year: 2020
Journal: Physiol Rep
Title: Denervation-induced muscle atrophy suppression in renalase-deficient mice via increased protein synthesis.
Volume: 8
Issue: 15
Pages: e14475
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Publication
25295465 | J:218301
First Author: Sonawane PJ
Year: 2014
Journal: Biochemistry
Title: Transcriptional regulation of the novel monoamine oxidase renalase: Crucial roles of transcription factors Sp1, STAT3, and ZBP89.
Volume: 53
Issue: 44
Pages: 6878-92
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Publication
25497549 | J:250934
First Author: Du M
Year: 2015
Journal: Cardiovasc Res
Title: Renalase is a novel target gene of hypoxia-inducible factor-1 in protection against cardiac ischaemia-reperfusion injury.
Volume: 105
Issue: 2
Pages: 182-91
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Allele
Rnls<em1Smoc> | MGI:7292093
Name: renalase, FAD-dependent amine oxidase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6476195 | C57BL/6-Rnls<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
26197969 | J:225639
First Author: Walker AK
Year: 2015
Journal: Acta Neuropathol
Title: Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43.
Volume: 130
Issue: 5
Pages: 643-60
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Publication
37118836 | J:335444
First Author: Swanson MEV
Year: 2023
Journal: Acta Neuropathol Commun
Title: Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain.
Volume: 11
Issue: 1
Pages: 69
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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