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Search results 1 to 100 out of 141 for Ro60

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Hits by Strain

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Type Details Score
Gene
6738 | RO60
Type: gene
Organism: human
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Gene
745289 | RO60
Type: gene
Organism: chimpanzee
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Gene
518830 | RO60
Type: gene
Organism: cattle
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Gene
568429 | ro60
Type: gene
Organism: zebrafish
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Gene
715194 | RO60
Type: gene
Organism: macaque, rhesus
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Gene
100497068 | ro60
Type: gene
Organism: frog, western clawed
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Gene
304833 | Ro60
Type: gene
Organism: rat
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Gene
478957 | RO60
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:106652 | Ro60
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23698747 | J:205377
First Author: Reed JH
Year: 2013
Journal: J Immunol
Title: Ro60 requires Y3 RNA for cell surface exposure and inflammation associated with cardiac manifestations of neonatal lupus.
Volume: 191
Issue: 1
Pages: 110-6
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Publication
9112230 | J:40092
First Author: Wang D
Year: 1996
Journal: Mol Biol Rep
Title: Cloning and expression of mouse 60 kDa ribonucleoprotein SS-A/Ro.
Volume: 23
Issue: 3-4
Pages: 205-10
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Publication
10323459 | J:65311
First Author: Scofield RH
Year: 1999
Journal: Arthritis Rheum
Title: Immunization of mice with human 60-kd Ro peptides results in epitope spreading if the peptides are highly homologous between human and mouse.
Volume: 42
Issue: 5
Pages: 1017-24
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Publication
21289087 | J:182871
First Author: Lai CK
Year: 2011
Journal: Mol Biol Cell
Title: Functional characterization of putative cilia genes by high-content analysis.
Volume: 22
Issue: 7
Pages: 1104-19
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Publication
26382853 | -
First Author: Hung T
Year: 2015
Journal: Science
Title: The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression.
Volume: 350
Issue: 6259
Pages: 455-9
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Protein
O08848
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0014676 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016563 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016546 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016511 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016506 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016331 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_106652 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015910 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016305 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016411 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016409 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016435 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017003 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015696 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015973 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027912 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015483 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12788971 | J:84627
First Author: Xue D
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen.
Volume: 100
Issue: 13
Pages: 7503-8
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Publication
14680639 | J:203110
First Author: Chen X
Year: 2003
Journal: Curr Biol
Title: The Ro autoantigen binds misfolded U2 small nuclear RNAs and assists mammalian cell survival after UV irradiation.
Volume: 13
Issue: 24
Pages: 2206-11
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GXD Expression
GXD Expression
 
Probe: MGI:3065858
Assay Type: RNA in situ
Annotation Date: 2009-01-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1603911
Pattern: Ubiquitous
Stage: TS11
Assay Id: MGI:3828805
Age: embryonic day 7.5
Image: E7.5
Specimen Label: E7.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3065858
Assay Type: RNA in situ
Annotation Date: 2009-01-23
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:3828805
Age: embryonic day 8.5
Image: E8.5
Note: Expression is weak to non-existent.
Specimen Label: E8.5
Specimen Num: 2
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Publication
- | J:65312
   
First Author: Kaufman KM
Year: 1999
Journal: GenBank Submission
Title: Mus musculus 60 kDa ribonucleoprotein SSA/Ro gene, complete cds
Pages: AF065398
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Publication
8625517 | J:32812
First Author: Keech CL
Year: 1996
Journal: Clin Exp Immunol
Title: Structural differences between the human and mouse 52-kD Ro autoantigens associated with poorly conserved autoantibody activity across species.
Volume: 104
Issue: 2
Pages: 255-63
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Publication
16365832 | J:109577
First Author: Fullerton J
Year: 2006
Journal: Behav Genet
Title: New approaches to the genetic analysis of neuroticism and anxiety.
Volume: 36
Issue: 1
Pages: 147-61
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Publication
21048919 | J:166694
First Author: Al-Shami A
Year: 2010
Journal: PLoS One
Title: Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development.
Volume: 5
Issue: 10
Pages: e13654
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Publication
15489855 | J:93903
First Author: Yalcin B
Year: 2004
Journal: Nat Genet
Title: Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice.
Volume: 36
Issue: 11
Pages: 1197-202
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Publication
26951610 | J:233532
First Author: Scekic-Zahirovic J
Year: 2016
Journal: EMBO J
Title: Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
Volume: 35
Issue: 10
Pages: 1077-97
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Publication
34323105 | J:321251
First Author: Yang N
Year: 2022
Journal: J Dent Res
Title: Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.
Volume: 101
Issue: 2
Pages: 226-234
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18973680 | J:141291
 
First Author: Tamplin OJ
Year: 2008
Journal: BMC Genomics
Title: Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Volume: 9
Pages: 511
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: RNA-binding protein Ro60
Type: chain
End: 538
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Publication
18056422 | -
First Author: Hogg JR
Year: 2007
Journal: Genes Dev
Title: Human Y5 RNA specializes a Ro ribonucleoprotein for 5S ribosomal RNA quality control.
Volume: 21
Issue: 23
Pages: 3067-72
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Protein Domain
IPR040322 | TROVE2
Type: Family
Description: Proteins in this family contain a TROVE (Telomerase, Ro and Vault) domain and include RNA-binding protein RO60 (TROVE2), an RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs [, ].
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Publication
11196703 | -
First Author: Kaufman KM
Year: 2000
Journal: Genes Immun
Title: Characterization and genomic sequence of the murine 60 kD Ro gene.
Volume: 1
Issue: 4
Pages: 265-70
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Allele
Ro60<em1Smoc> | MGI:7292095
Name: Ro60, Y RNA binding protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein
Q8R562
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
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Protein
Q80W12
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
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Protein
Q3TJ75
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
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SO Term
SO:0000405 | Y_RNA
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Publication
12657529 | J:82259
First Author: Laderach D
Year: 2003
Journal: J Autoimmun
Title: Concomitant early appearance of anti-ribonucleoprotein and anti-nucleosome antibodies in lupus prone mice.
Volume: 20
Issue: 2
Pages: 161-70
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Publication
9933452 | J:52595
First Author: Kinoshita G
Year: 1999
Journal: Clin Exp Immunol
Title: Molecular chaperones are targets of autoimmunity in Ro(SS-A) immune mice.
Volume: 115
Issue: 2
Pages: 268-74
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Protein
A0A2R8VHW8
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: false
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Protein
Q497V3
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
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Protein Domain
IPR045180 | La_dom_prot
Type: Family
Description: Human Ro ribonucleoproteins (RNPs) are composed of one of the four small Y RNAs and at least two proteins, Ro60 and La. The La protein is a 47kDa polypeptide that frequently acts as an autoantigen in systemic lupus erythematosus and Sjogren's syndrome []. In the nucleus, La acts as a RNA polymerase III (RNAP III) transcription factor, while in the cytoplasm, La acts as a translation factor []. In the nucleus, La binds to the 3'UTR of nascent RNAP III transcripts to assist in folding and maturation []. In the cytoplasm, La recognises specific classes of mRNAs that contain a 5'-terminal oligopyrimidine (5'TOP) motif known to control protein synthesis []. The specific recognition is mediated by the N-terminal domain of La, which comprises a La motif and a RNA recognition motif (RRM). The La motif adopts an alpha/beta fold that comprises a winged-helix motif [].Homologous La domain-containing proteins have been identified in a wide range of organisms except Archaea, bacteria and viruses [].
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Protein Domain
IPR037214 | TROVE_dom_sf
Type: Homologous_superfamily
Description: The TROVE (Telomerase, Ro and Vault) domain is a module of ~300-500 residues that is found in TEP1 and Ro60 the protein components of three ribonucleoprotein particles. It is also found in bacterial ribonucleoproteins suggesting an ancient origin of these ribonucleoproteins. It can be found associated with other domains, such as the VWFA domain, the TEP1 N-terminal domain, the NACHT-NTPase domain, and WD-40 repeats. This domain may be involved in binding the RNA components of the three RNPs, which are telomerase RNA, Y RNA and vault RNA [].The TROVE domain contains a few absolutely conserved residues. As none of these conserved residues are the polar type of amino acids found in active sites, it seems unlikely that this region has an enzymatic function [].Structurally, the TROVE domain consist of two superhelical sections arranged like a horse-shoe.
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Protein Domain
IPR008858 | TROVE_dom
Type: Domain
Description: The TROVE (Telomerase, Ro and Vault) domain is a module of ~300-500 residues that is found in TEP1 and Ro60 the protein components of three ribonucleoprotein particles. It is also found in bacterial ribonucleoproteins suggesting an ancient origin of these ribonucleoproteins. It can be found associated with other domains, such as the VWFA domain, the TEP1 N-terminal domain, the NACHT-NTPase domain, and WD-40 repeats. This domain may be involved in binding the RNA components of the three RNPs, which are telomerase RNA, Y RNA and vault RNA [].The TROVE domain contains a few absolutely conserved residues. As none of these conserved residues are the polar type of amino acids found in active sites, it seems unlikely that this region has an enzymatic function [].
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Publication
14563212 | -
 
First Author: Bateman A
Year: 2003
Journal: BMC Bioinformatics
Title: The TROVE module: a common element in Telomerase, Ro and Vault ribonucleoproteins.
Volume: 4
Pages: 49
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Publication
7799435 | -
First Author: Lin-Marq N
Year: 1995
Journal: J Mol Biol
Title: A yeast RNA binding protein that resembles the human autoantigen La.
Volume: 245
Issue: 2
Pages: 81-5
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Publication
15048103 | -
First Author: Kenan DJ
Year: 2004
Journal: Nat Struct Mol Biol
Title: La gets its wings.
Volume: 11
Issue: 4
Pages: 303-5
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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