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Search results 1 to 100 out of 450 for Rock2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Wei L
Year: 2020
Journal: FASEB J
Title: ROCK2 inhibition enhances the thermogenic program in white and brown fat tissue in mice.
Volume: 34
Issue: 1
Pages: 474-493
Publication
First Author: Singh RK
Year: 2014
Journal: Mol Cell
Title: Rbfox2-coordinated alternative splicing of Mef2d and Rock2 controls myoblast fusion during myogenesis.
Volume: 55
Issue: 4
Pages: 592-603
Publication  
First Author: Greathouse KM
Year: 2019
Journal: Behav Brain Res
Title: Fasudil or genetic depletion of ROCK1 or ROCK2 induces anxiety-like behaviors.
Volume: 373
Pages: 112083
Publication  
First Author: Shimizu T
Year: 2017
Journal: JCI Insight
Title: Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction.
Volume: 2
Issue: 13
Publication
First Author: Shimizu T
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Crucial role of ROCK2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice.
Volume: 33
Issue: 12
Pages: 2780-91
Publication
First Author: Ricker E
Year: 2020
Journal: J Clin Invest
Title: Serine-threonine kinase ROCK2 regulates germinal center B cell positioning and cholesterol biosynthesis.
Volume: 130
Issue: 7
Pages: 3654-3670
Publication
First Author: Soliman H
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: Partial deletion of ROCK2 protects mice from high-fat diet-induced cardiac insulin resistance and contractile dysfunction.
Volume: 309
Issue: 1
Pages: H70-81
Publication
First Author: Masre SF
Year: 2020
Journal: Carcinogenesis
Title: Epidermal ROCK2 induces AKT1/GSK3β/β-catenin, NFκB and dermal tenascin C; but enhanced differentiation and p53/p21 inhibit papilloma.
Volume: 41
Issue: 10
Pages: 1409-1420
Publication
First Author: McKerracher L
Year: 2020
Journal: Transl Stroke Res
Title: A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.
Volume: 11
Issue: 3
Pages: 365-376
Publication
First Author: Herskowitz JH
Year: 2013
Journal: J Neurosci
Title: Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model.
Volume: 33
Issue: 49
Pages: 19086-98
Publication
First Author: Zhou Z
Year: 2009
Journal: Neuropharmacology
Title: A critical role of Rho-kinase ROCK2 in the regulation of spine and synaptic function.
Volume: 56
Issue: 1
Pages: 81-9
Publication
First Author: Kasahara DI
Year: 2017
Journal: Clin Exp Allergy
Title: Role of ROCK2 in CD4+ cells in allergic airways responses in mice.
Volume: 47
Issue: 2
Pages: 224-235
Publication  
First Author: Shi J
Year: 2013
Journal: Cell Death Dis
Title: Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment.
Volume: 4
Pages: e483
Publication
First Author: Yan J
Year: 2019
Journal: Neurosci Bull
Title: Comparative Study of ROCK1 and ROCK2 in Hippocampal Spine Formation and Synaptic Function.
Volume: 35
Issue: 4
Pages: 649-660
Publication
First Author: Knipe RS
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.
Volume: 58
Issue: 4
Pages: 471-481
Publication
First Author: Pelosi M
Year: 2007
Journal: Mol Cell Biol
Title: ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program.
Volume: 27
Issue: 17
Pages: 6163-76
Publication
First Author: Weber AJ
Year: 2021
Journal: Mol Brain
Title: Conditional deletion of ROCK2 induces anxiety-like behaviors and alters dendritic spine density and morphology on CA1 pyramidal neurons.
Volume: 14
Issue: 1
Pages: 169
Publication
First Author: Ferrer I
Year: 2014
Journal: J Pathol
Title: Tubers from patients with tuberous sclerosis complex are characterized by changes in microtubule biology through ROCK2 signalling.
Volume: 233
Issue: 3
Pages: 247-57
Publication
First Author: Sunamura S
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Different roles of myocardial ROCK1 and ROCK2 in cardiac dysfunction and postcapillary pulmonary hypertension in mice.
Volume: 115
Issue: 30
Pages: E7129-E7138
GXD Expression      
Probe: MGI:6182413
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191221
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Rock2
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6182413
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191221
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Rock2
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6182413
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6191221
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Rock2
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6182413
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191221
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Rock2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6182413
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191221
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Rock2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6182413
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191221
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Rock2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6182413
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191221
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Rock2
Detected: true
Specimen Num: 7
Publication
First Author: Biswas PS
Year: 2010
Journal: J Clin Invest
Title: Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.
Volume: 120
Issue: 9
Pages: 3280-95
Publication
First Author: Shi J
Year: 2019
Journal: FASEB J
Title: Disruption of both ROCK1 and ROCK2 genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging.
Volume: 33
Issue: 6
Pages: 7348-7362
Publication
First Author: Greathouse KM
Year: 2018
Journal: Brain Struct Funct
Title: Distinct and complementary functions of rho kinase isoforms ROCK1 and ROCK2 in prefrontal cortex structural plasticity.
Volume: 223
Issue: 9
Pages: 4227-4241
Publication
First Author: Weiss JM
Year: 2016
Journal: Sci Signal
Title: ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings.
Volume: 9
Issue: 437
Pages: ra73
Publication
First Author: Samuel MS
Year: 2016
Journal: Genesis
Title: Tissue-selective expression of a conditionally-active ROCK2-estrogen receptor fusion protein.
Volume: 54
Issue: 12
Pages: 636-646
Publication
First Author: Samuel MS
Year: 2009
Journal: Genesis
Title: Tissue selective expression of conditionally-regulated ROCK by gene targeting to a defined locus.
Volume: 47
Issue: 7
Pages: 440-6
Publication
First Author: Matoba K
Year: 2022
Journal: Commun Biol
Title: ROCK2-induced metabolic rewiring in diabetic podocytopathy.
Volume: 5
Issue: 1
Pages: 341
Publication
First Author: Tanaka T
Year: 2006
Journal: J Biol Chem
Title: Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase.
Volume: 281
Issue: 22
Pages: 15320-9
Publication
First Author: Biswas PS
Year: 2011
Journal: Cell Immunol
Title: Aberrant ROCK activation promotes the development of type I diabetes in NOD mice.
Volume: 266
Issue: 2
Pages: 111-5
Publication
First Author: Sladojevic N
Year: 2017
Journal: Cardiovasc Res
Title: Decreased thromboembolic stroke but not atherosclerosis or vascular remodelling in mice with ROCK2-deficient platelets.
Volume: 113
Issue: 11
Pages: 1307-1317
Publication
First Author: Breyer J
Year: 2012
Journal: Biochem Pharmacol
Title: Inhibition of Rho kinases increases directional motility of microvascular endothelial cells.
Volume: 83
Issue: 5
Pages: 616-26
Publication  
First Author: Chen H
Year: 2020
Journal: Mol Immunol
Title: LncRNA THRIL aggravates sepsis-induced acute lung injury by regulating miR-424/ROCK2 axis.
Volume: 126
Pages: 111-119
Publication
First Author: Bobo-Jiménez V
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: APC/CCdh1-Rock2 pathway controls dendritic integrity and memory.
Volume: 114
Issue: 17
Pages: 4513-4518
Publication
First Author: Zheng K
Year: 2021
Journal: Nat Commun
Title: miR-135a-5p mediates memory and synaptic impairments via the Rock2/Adducin1 signaling pathway in a mouse model of Alzheimer's disease.
Volume: 12
Issue: 1
Pages: 1903
Publication
First Author: Saito T
Year: 2013
Journal: Circulation
Title: Pivotal role of Rho-associated kinase 2 in generating the intrinsic circadian rhythm of vascular contractility.
Volume: 127
Issue: 1
Pages: 104-14
Publication
First Author: Zhou Q
Year: 2012
Journal: Circulation
Title: Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased atherosclerosis.
Volume: 126
Issue: 18
Pages: 2236-47
Publication
First Author: Noma K
Year: 2008
Journal: J Clin Invest
Title: ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury.
Volume: 118
Issue: 5
Pages: 1632-44
Publication
First Author: Kasahara DI
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice.
Volume: 309
Issue: 7
Pages: L736-46
Publication
First Author: Yao L
Year: 2013
Journal: Cardiovasc Res
Title: Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout.
Volume: 97
Issue: 3
Pages: 509-19
Publication
First Author: Zhao Z
Year: 2004
Journal: Dev Biol
Title: Rho-associated kinases play a role in endocardial cell differentiation and migration.
Volume: 275
Issue: 1
Pages: 183-91
Publication
First Author: Mong PY
Year: 2009
Journal: J Immunol
Title: Activation of Rho kinase isoforms in lung endothelial cells during inflammation.
Volume: 182
Issue: 4
Pages: 2385-94
Publication
First Author: Vega FM
Year: 2011
Journal: J Cell Biol
Title: RhoA and RhoC have distinct roles in migration and invasion by acting through different targets.
Volume: 193
Issue: 4
Pages: 655-65
Publication
First Author: Leong SY
Year: 2011
Journal: Stem Cells
Title: The Rho kinase pathway regulates mouse adult neural precursor cell migration.
Volume: 29
Issue: 2
Pages: 332-43
Publication
First Author: Laeno AM
Year: 2013
Journal: Biol Reprod
Title: Rho-associated kinase activity is required for proper morphogenesis of the inner cell mass in the mouse blastocyst.
Volume: 89
Issue: 5
Pages: 122
Publication  
First Author: Kümper S
Year: 2016
Journal: Elife
Title: Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis.
Volume: 5
Pages: e12994
Publication
First Author: Okamoto R
Year: 2013
Journal: FASEB J
Title: FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2.
Volume: 27
Issue: 4
Pages: 1439-49
Publication
First Author: Whitlock NA
Year: 2009
Journal: J Ocul Pharmacol Ther
Title: Decreased intraocular pressure in mice following either pharmacological or genetic inhibition of ROCK.
Volume: 25
Issue: 3
Pages: 187-94
Publication
First Author: Gallo RM
Year: 2012
Journal: J Immunol
Title: Regulation of the actin cytoskeleton by Rho kinase controls antigen presentation by CD1d.
Volume: 189
Issue: 4
Pages: 1689-98
Publication
First Author: Han Y
Year: 2015
Journal: J Neurochem
Title: Noise-induced cochlear F-actin depolymerization is mediated via ROCK2/p-ERM signaling.
Volume: 133
Issue: 5
Pages: 617-28
Publication  
First Author: Harris SL
Year: 2017
Journal: Neuroscience
Title: Conditional deletion of pejvakin in adult outer hair cells causes progressive hearing loss in mice.
Volume: 344
Pages: 380-393
Publication
First Author: Rath N
Year: 2017
Journal: EMBO Mol Med
Title: ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth.
Volume: 9
Issue: 2
Pages: 198-218
Publication
First Author: Hiroi Y
Year: 2018
Journal: Circ J
Title: Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice.
Volume: 82
Issue: 4
Pages: 1195-1204
Publication
First Author: Sun S
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Lin28a protects against diabetic cardiomyopathy via the PKA/ROCK2 pathway.
Volume: 469
Issue: 1
Pages: 29-36
Publication
First Author: Flynn R
Year: 2016
Journal: Blood
Title: Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.
Volume: 127
Issue: 17
Pages: 2144-54
Publication    
First Author: Bailey KE
Year: 2019
Journal: JCI Insight
Title: Disruption of embryonic ROCK signaling reproduces the sarcomeric phenotype of hypertrophic cardiomyopathy.
Volume: 5
Publication
First Author: Phillips HM
Year: 2013
Journal: Cardiovasc Res
Title: Neural crest cells are required for correct positioning of the developing outflow cushions and pattern the arterial valve leaflets.
Volume: 99
Issue: 3
Pages: 452-60
Publication
First Author: Masre SF
Year: 2017
Journal: Oncogene
Title: ROCK2/rasHa co-operation induces malignant conversion via p53 loss, elevated NF-κB and tenascin C-associated rigidity, but p21 inhibits ROCK2/NF-κB-mediated progression.
Volume: 36
Issue: 18
Pages: 2529-2542
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Duffy P
Year: 2009
Journal: J Neurosci
Title: Rho-associated kinase II (ROCKII) limits axonal growth after trauma within the adult mouse spinal cord.
Volume: 29
Issue: 48
Pages: 15266-76
Publication
First Author: Katoh K
Year: 2007
Journal: Genes Cells
Title: Rho-kinase dependent organization of stress fibers and focal adhesions in cultured fibroblasts.
Volume: 12
Issue: 5
Pages: 623-38
Publication
First Author: Lee HH
Year: 2010
Journal: J Cell Sci
Title: Src-dependent phosphorylation of ROCK participates in regulation of focal adhesion dynamics.
Volume: 123
Issue: Pt 19
Pages: 3368-77
Publication
First Author: Meyer-Schwesinger C
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Rho-kinase inhibition prevents proteinuria in immune-complex-mediated antipodocyte nephritis.
Volume: 303
Issue: 7
Pages: F1015-25
GXD Expression    
Probe: MGI:3053195
Assay Type: Western blot
Annotation Date: 2004-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3053201
Age: embryonic day 18.5
Image: 3
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3053195
Assay Type: Western blot
Annotation Date: 2004-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3053201
Age: embryonic day 18.5
Image: 3
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3053195
Assay Type: Western blot
Annotation Date: 2004-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3053201
Age: embryonic day 18.5
Image: 3
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3804901
Assay Type: RT-PCR
Annotation Date: 2008-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1669615
Stage: TS15
Assay Id: MGI:3804903
Age: embryonic day 9.5
Image: 1
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3804901
Assay Type: RT-PCR
Annotation Date: 2008-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1669617
Stage: TS17
Assay Id: MGI:3804903
Age: embryonic day 10.5
Image: 1
Specimen Label: 2
Detected: true
Specimen Num: 2