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Search results 1 to 100 out of 505 for Rpe65

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Type Details Score
Gene
6121 | RPE65
Type: gene
Organism: human
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Gene
282043 | RPE65
Type: gene
Organism: cattle
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Gene
701764 | RPE65
Type: gene
Organism: macaque, rhesus
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Gene
89826 | Rpe65
Type: gene
Organism: rat
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Gene
403803 | RPE65
Type: gene
Organism: dog, domestic
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Gene
744567 | RPE65
Type: gene
Organism: chimpanzee
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Gene
395700 | RPE65
Type: gene
Organism: chicken
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Gene
100145692 | rpe65
Type: gene
Organism: frog, western clawed
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Protein Coding Gene
MGI:98001 | Rpe65
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30242264 | J:279145
First Author: Kolesnikov AV
Year: 2018
Journal: Sci Rep
Title: Examining the Role of Cone-expressed RPE65 in Mouse Cone Function.
Volume: 8
Issue: 1
Pages: 14201
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Publication
23778877 | J:214189
First Author: Wright CB
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Complementation test of Rpe65 knockout and tvrm148.
Volume: 54
Issue: 7
Pages: 5111-22
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Publication
- | J:88921
   
First Author: Chang B
Year: 2001
Journal: GenBank Submission
Title: Mus musculus RPE65 (Rpe65) mRNA, complete cds
Pages: AF410461
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Publication
11150319 | J:66951
First Author: Wenzel A
Year: 2001
Journal: J Neurosci
Title: The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration.
Volume: 21
Issue: 1
Pages: 53-8
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Publication
11980880 | J:119273
First Author: Znoiko SL
Year: 2002
Journal: Invest Ophthalmol Vis Sci
Title: Identification of the RPE65 protein in mammalian cone photoreceptors.
Volume: 43
Issue: 5
Pages: 1604-9
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Publication
16519667 | J:107147
First Author: Samardzija M
Year: 2006
Journal: Eur J Neurosci
Title: Rpe65 as a modifier gene for inherited retinal degeneration.
Volume: 23
Issue: 4
Pages: 1028-34
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Publication
27768794 | J:254685
First Author: Zhong X
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Fundus Camera-Delivered Light-Induced Retinal Degeneration in Mice With the RPE65 Leu450Met Variant is Associated With Oxidative Stress and Apoptosis.
Volume: 57
Issue: 13
Pages: 5558-5567
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Publication
24644049 | J:229806
First Author: Wright CB
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: The Rpe65 rd12 allele exerts a semidominant negative effect on vision in mice.
Volume: 55
Issue: 4
Pages: 2500-15
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Publication
28500718 | J:250439
First Author: Sheridan C
Year: 2017
Journal: Photochem Photobiol
Title: RPE65 and the Accumulation of Retinyl Esters in Mouse Retinal Pigment Epithelium.
Volume: 93
Issue: 3
Pages: 844-848
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Publication
21169527 | J:171546
First Author: Li X
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Gene therapy rescues cone structure and function in the 3-month-old rd12 mouse: a model for midcourse RPE65 leber congenital amaurosis.
Volume: 52
Issue: 1
Pages: 7-15
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Publication
14578454 | J:86548
First Author: Fan J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Isorhodopsin rather than rhodopsin mediates rod function in RPE65 knock-out mice.
Volume: 100
Issue: 23
Pages: 13662-7
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Publication
21551411 | J:181416
First Author: Hu Y
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Comparison of ocular pathologies in vitamin A-deficient mice and RPE65 gene knockout mice.
Volume: 52
Issue: 8
Pages: 5507-14
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Publication
15837919 | J:98215
First Author: Jacobson SG
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success.
Volume: 102
Issue: 17
Pages: 6177-82
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Publication
16505056 | J:108379
First Author: Chen Y
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice.
Volume: 47
Issue: 3
Pages: 1177-84
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Publication
20484585 | J:171404
First Author: Caruso RC
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Retinal disease in Rpe65-deficient mice: comparison to human leber congenital amaurosis due to RPE65 mutations.
Volume: 51
Issue: 10
Pages: 5304-13
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Publication
16714237 | J:119871
First Author: Lu Z
Year: 2006
Journal: Curr Eye Res
Title: Identification of a KRAB-zinc finger protein binding to the Rpe65 gene promoter.
Volume: 31
Issue: 5
Pages: 457-66
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Publication
11687551 | J:72925
First Author: Katz ML
Year: 2001
Journal: Invest Ophthalmol Vis Sci
Title: Effect of Rpe65 knockout on accumulation of lipofuscin fluorophores in the retinal pigment epithelium.
Volume: 42
Issue: 12
Pages: 3023-30
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Publication
9843205 | J:51293
First Author: Redmond TM
Year: 1998
Journal: Nat Genet
Title: Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.
Volume: 20
Issue: 4
Pages: 344-51
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Publication
18326740 | J:133023
First Author: Feathers KL
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Nrl-knockout mice deficient in Rpe65 fail to synthesize 11-cis retinal and cone outer segments.
Volume: 49
Issue: 3
Pages: 1126-35
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Publication
- | J:94549
First Author: Chang B
Year: 2002
Journal: Invest Ophthalmol Vis Sci
Title: A point mutation in the Rpe65 gene causes retinal degeneration (rd12) in mice. (The Association for Research in Vision & Ophthalmology Annual Meeting Abstract)
Volume: 43
Issue: 13
Pages: 3670
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Publication
17251447 | J:123283
First Author: Wenzel A
Year: 2007
Journal: Invest Ophthalmol Vis Sci
Title: RPE65 is essential for the function of cone photoreceptors in NRL-deficient mice.
Volume: 48
Issue: 2
Pages: 534-42
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Publication
15722110 | J:98275
First Author: Katz ML
Year: 2005
Journal: Mech Ageing Dev
Title: RPE65 gene mutation prevents development of autofluorescence in retinal pigment epithelial phagosomes.
Volume: 126
Issue: 4
Pages: 513-21
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Publication
11483174 | J:102672
First Author: Ekesten B
Year: 2001
Journal: Vision Res
Title: Ultraviolet and middle wavelength sensitive cone responses in the electroretinogram (ERG) of normal and Rpe65 -/- mice.
Volume: 41
Issue: 19
Pages: 2425-33
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Publication
17933883 | J:130076
First Author: Samardzija M
Year: 2008
Journal: Hum Mol Genet
Title: R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal.
Volume: 17
Issue: 2
Pages: 281-92
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Publication
15277666 | J:99461
First Author: Kim SR
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E.
Volume: 101
Issue: 32
Pages: 11668-72
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Publication
- | J:94351
First Author: Pang JJ
Year: 2004
Journal: Invest Ophthalmol Vis Sci
Title: Gene therapy restores vision in a natural model of RPE65 Leber congenital amaurosis: The rd12 mouse (The Association for Research in Vision & Ophthalmology Annual Meeting Abstracts)
Volume: 45
Issue: 13
Pages: 3486
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Publication
32841098 | J:302963
First Author: Harrison KR
Year: 2021
Journal: Curr Eye Res
Title: Prolonged Melanopsin-based Photoresponses Depend in Part on RPE65 and Cellular Retinaldehyde-binding Protein (CRALBP).
Volume: 46
Issue: 4
Pages: 515-523
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Publication
8034329 | J:17610
First Author: Hamel CP
Year: 1994
Journal: Genomics
Title: The gene for the retinal pigment epithelium-specific protein RPE65 is localized to human 1p31 and mouse 3.
Volume: 20
Issue: 3
Pages: 509-12
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Publication
29038159 | J:253672
 
First Author: Pyakurel A
Year: 2017
Journal: Mol Cell Biol
Title: Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration.
Volume: 37
Issue: 24
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Publication
16788070 | J:111699
First Author: Doyle SE
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Nonvisual light responses in the Rpe65 knockout mouse: rod loss restores sensitivity to the melanopsin system.
Volume: 103
Issue: 27
Pages: 10432-7
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Publication
15112105 | J:89728
First Author: Danciger M
Year: 2004
Journal: Mamm Genome
Title: New retinal light damage QTL in mice with the light-sensitive RPE65 LEU variant.
Volume: 15
Issue: 4
Pages: 277-83
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Publication
20876139 | J:165400
First Author: Moiseyev G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease.
Volume: 107
Issue: 41
Pages: 17551-6
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Publication
33257550 | J:301332
First Author: Li S
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Inverse correlation between fatty acid transport protein 4 and vision in Leber congenital amaurosis associated with RPE65 mutation.
Volume: 117
Issue: 50
Pages: 32114-32123
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Publication
30628748 | J:292577
First Author: Li Y
Year: 2019
Journal: Hum Mutat
Title: Aberrant RNA splicing is the major pathogenic effect in a knock-in mouse model of the dominantly inherited c.1430A>G human RPE65 mutation.
Volume: 40
Issue: 4
Pages: 426-443
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Publication
25972377 | J:223999
First Author: Li Y
Year: 2015
Journal: Hum Mol Genet
Title: Mouse model of human RPE65 P25L hypomorph resembles wild type under normal light rearing but is fully resistant to acute light damage.
Volume: 24
Issue: 15
Pages: 4417-28
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Publication
10896939 | J:65017
First Author: Boulanger A
Year: 2000
Journal: J Biol Chem
Title: The upstream region of the Rpe65 gene confers retinal pigment epithelium-specific expression in vivo and in vitro and contains critical octamer and E-box binding sites.
Volume: 275
Issue: 40
Pages: 31274-82
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Publication
11528395 | J:71529
First Author: Seeliger MW
Year: 2001
Journal: Nat Genet
Title: New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis.
Volume: 29
Issue: 1
Pages: 70-4
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Publication
31692906 | J:285429
First Author: Jo DH
Year: 2019
Journal: Sci Adv
Title: CRISPR-Cas9-mediated therapeutic editing of Rpe65 ameliorates the disease phenotypes in a mouse model of Leber congenital amaurosis.
Volume: 5
Issue: 10
Pages: eaax1210
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Publication
14550405 | J:86186
First Author: Nusinowitz S
Year: 2003
Journal: Exp Eye Res
Title: Electroretinographic evidence for altered phototransduction gain and slowed recovery from photobleaches in albino mice with a MET450 variant in RPE65.
Volume: 77
Issue: 5
Pages: 627-38
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Gene
100002865 | rpe65b
Type: gene
Organism: zebrafish
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Gene
100004076 | rpe65c
Type: gene
Organism: zebrafish
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Gene
393724 | rpe65a
Type: gene
Organism: zebrafish
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Publication
10818205 | J:62583
First Author: Danciger M
Year: 2000
Journal: Mamm Genome
Title: A QTL on distal chromosome 3 that influences the severity of light-induced damage to mouse photoreceptors.
Volume: 11
Issue: 6
Pages: 422-7
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Publication
23274583 | J:210431
 
First Author: Bai S
Year: 2013
Journal: Exp Eye Res
Title: NAD(+) maintenance attenuates light induced photoreceptor degeneration.
Volume: 108
Pages: 76-83
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Publication
19060264 | J:146669
First Author: Berkowitz BA
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Quantitative mapping of ion channel regulation by visual cycle activity in rodent photoreceptors in vivo.
Volume: 50
Issue: 4
Pages: 1880-5
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Publication
22953002 | J:191645
First Author: Zheng Q
Year: 2012
Journal: PLoS One
Title: Differential proteomics and functional research following gene therapy in a mouse model of Leber congenital amaurosis.
Volume: 7
Issue: 8
Pages: e44855
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Publication
30115683 | J:272883
First Author: Li S
Year: 2018
Journal: J Biol Chem
Title: Ciliary neurotrophic factor (CNTF) protects retinal cone and rod photoreceptors by suppressing excessive formation of the visual pigments.
Volume: 293
Issue: 39
Pages: 15256-15268
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Publication
17130236 | J:118293
First Author: Kurth I
Year: 2007
Journal: Mol Cell Biol
Title: Targeted disruption of the murine retinal dehydrogenase gene Rdh12 does not limit visual cycle function.
Volume: 27
Issue: 4
Pages: 1370-9
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Publication
15765048 | J:104924
 
First Author: Pang JJ
Year: 2005
Journal: Mol Vis
Title: Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA).
Volume: 11
Pages: 152-62
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Publication
30042155 | J:265177
 
First Author: Dannhausen K
Year: 2018
Journal: Dis Model Mech
Title: Immunomodulation with minocycline rescues retinal degeneration in juvenile neuronal ceroid lipofuscinosis mice highly susceptible to light damage.
Volume: 11
Issue: 9
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Publication
12766089 | J:119424
First Author: Wenzel A
Year: 2003
Journal: Invest Ophthalmol Vis Sci
Title: The genetic modifier Rpe65Leu(450): effect on light damage susceptibility in c-Fos-deficient mice.
Volume: 44
Issue: 6
Pages: 2798-802
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Publication
32188692 | J:298575
First Author: Lima de Carvalho JR Jr
Year: 2020
Journal: J Biol Chem
Title: Effects of deficiency in the RLBP1-encoded visual cycle protein CRALBP on visual dysfunction in humans and mice.
Volume: 295
Issue: 19
Pages: 6767-6780
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Publication
24576873 | J:229504
First Author: Wu L
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Light damage in Abca4 and Rpe65rd12 mice.
Volume: 55
Issue: 3
Pages: 1910-8
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Publication
32958638 | J:296454
First Author: Kim HJ
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Vitamin A aldehyde-taurine adduct and the visual cycle.
Volume: 117
Issue: 40
Pages: 24867-24875
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Publication
23274584 | J:210430
 
First Author: Bai S
Year: 2013
Journal: Exp Eye Res
Title: A reduced zinc diet or zinc transporter 3 knockout attenuate light induced zinc accumulation and retinal degeneration.
Volume: 108
Pages: 59-67
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Publication
19193895 | J:144944
First Author: Jin M
Year: 2009
Journal: J Neurosci
Title: The role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptors.
Volume: 29
Issue: 5
Pages: 1486-95
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Publication
30352873 | J:272819
First Author: Zhao J
Year: 2018
Journal: J Biol Chem
Title: Bisretinoids mediate light sensitivity resulting in photoreceptor cell degeneration in mice lacking the receptor tyrosine kinase Mer.
Volume: 293
Issue: 50
Pages: 19400-19410
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Publication
23009755 | J:197502
 
First Author: Braunger BM
Year: 2013
Journal: Neurobiol Dis
Title: Constitutive overexpression of Norrin activates Wnt/β-catenin and endothelin-2 signaling to protect photoreceptors from light damage.
Volume: 50
Pages: 1-12
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Publication
34582935 | J:331188
 
First Author: Dai X
Year: 2021
Journal: Exp Eye Res
Title: Intraperitoneal chromophore injections delay early-onset and rapid retinal cone degeneration in a mouse model of Leber congenital amaurosis.
Volume: 212
Pages: 108776
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Publication
27225770 | J:327035
First Author: Li S
Year: 2016
Journal: J Neurosci
Title: Pharmacological Amelioration of Cone Survival and Vision in a Mouse Model for Leber Congenital Amaurosis.
Volume: 36
Issue: 21
Pages: 5808-19
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Publication
20007830 | J:160802
First Author: Brunner S
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Cone versus rod disease in a mutant Rpgr mouse caused by different genetic backgrounds.
Volume: 51
Issue: 2
Pages: 1106-15
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Publication
21493626 | J:173770
First Author: Lopes VS
Year: 2011
Journal: Hum Mol Genet
Title: The Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65.
Volume: 20
Issue: 13
Pages: 2560-70
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Publication
18515598 | J:137044
First Author: Thompson S
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Divergent phenotypes of vision and accessory visual function in mice with visual cycle dysfunction (Rpe65 rd12) or retinal degeneration (rd/rd).
Volume: 49
Issue: 6
Pages: 2737-42
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Publication
25706871 | J:226302
First Author: Dai X
Year: 2015
Journal: PLoS One
Title: The frequency-response electroretinogram distinguishes cone and abnormal rod function in rd12 mice.
Volume: 10
Issue: 2
Pages: e0117570
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Publication
22886305 | J:191429
First Author: Han Z
Year: 2012
Journal: J Clin Invest
Title: DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice.
Volume: 122
Issue: 9
Pages: 3221-6
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Publication
29847651 | J:281937
First Author: Paavo M
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Mutations in GPR143/OA1 and ABCA4 Inform Interpretations of Short-Wavelength and Near-Infrared Fundus Autofluorescence.
Volume: 59
Issue: 6
Pages: 2459-2469
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Publication
21464132 | J:173786
First Author: Radu RA
Year: 2011
Journal: J Biol Chem
Title: Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration.
Volume: 286
Issue: 21
Pages: 18593-601
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Publication
29871924 | J:267104
First Author: Racz B
Year: 2018
Journal: J Biol Chem
Title: A non-retinoid antagonist of retinol-binding protein 4 rescues phenotype in a model of Stargardt disease without inhibiting the visual cycle.
Volume: 293
Issue: 29
Pages: 11574-11588
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Publication
22786896 | J:213974
First Author: Secondi R
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Fundus autofluorescence findings in a mouse model of retinal detachment.
Volume: 53
Issue: 9
Pages: 5190-7
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Publication
27503804 | J:279794
 
First Author: Hasegawa T
Year: 2016
Journal: Sci Rep
Title: Neuoroprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration.
Volume: 6
Pages: 31184
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Publication
18644591 | J:141999
First Author: Guerin K
Year: 2008
Journal: Exp Eye Res
Title: Systemic aminoglycoside treatment in rodent models of retinitis pigmentosa.
Volume: 87
Issue: 3
Pages: 197-207
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Publication
19506076 | J:153181
First Author: Chrispell JD
Year: 2009
Journal: J Biol Chem
Title: Rdh12 activity and effects on retinoid processing in the murine retina.
Volume: 284
Issue: 32
Pages: 21468-77
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Publication
10869443 | J:63407
First Author: Van Hooser JP
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness.
Volume: 97
Issue: 15
Pages: 8623-8
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Publication
29773803 | J:262864
First Author: Chen Y
Year: 2018
Journal: Nat Commun
Title: A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.
Volume: 9
Issue: 1
Pages: 1976
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Publication
19494204 | J:154536
First Author: Maeda T
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance.
Volume: 50
Issue: 10
Pages: 4917-25
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Publication
29401616 | J:267644
First Author: Schur RM
Year: 2018
Journal: FASEB J
Title: New GABA modulators protect photoreceptor cells from light-induced degeneration in mouse models.
Volume: 32
Issue: 6
Pages: 3289-3300
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Publication
27274068 | J:234295
First Author: Ueda K
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Photodegradation of retinal bisretinoids in mouse models and implications for macular degeneration.
Volume: 113
Issue: 25
Pages: 6904-9
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Publication
22039245 | J:191397
First Author: Yamamoto K
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: A novel bisretinoid of retina is an adduct on glycerophosphoethanolamine.
Volume: 52
Issue: 12
Pages: 9084-90
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Publication
28348233 | J:242022
First Author: Lenis TL
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease.
Volume: 114
Issue: 15
Pages: 3987-3992
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Publication
37659708 | J:341373
 
First Author: Ramachandra Rao S
Year: 2023
Journal: Exp Eye Res
Title: A simple, rapid fluorescent reporter-based method for detection of ectopic cre recombinase expression in presumed retinal cell type-targeted mouse lines.
Volume: 235
Pages: 109637
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Publication
33299105 | J:301483
First Author: Nagai N
Year: 2020
Journal: Commun Biol
Title: Renin-angiotensin system impairs macrophage lipid metabolism to promote age-related macular degeneration in mouse models.
Volume: 3
Issue: 1
Pages: 767
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Publication
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